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Papers by rıdvan polat

Biyolojik Çeşitlilik ve Koruma, Dec 15, 2016

South African Journal of Botany, 2021

Abstract The lack of ethnoveterinary surveys in Turkey, results in losses in the veterinary phyto... more Abstract The lack of ethnoveterinary surveys in Turkey, results in losses in the veterinary phytopharmacology field. This is the first ethnoveterinary research in which statistical calculations about plants are done by informant consensus factor (ICF) method in the Blacksea Region of Turkey. To catalog, analyze, and disseminate the knowledge of plant use in ethnoveterinary practices in the province of Giresun (Turkey). Information was gathered through open and semi-structured interviews with local people, mainly elderly shepherds and farmers, in the Giresun province. The collected data was analyzed quantitatively using two indices, informant consensus factor (ICF). A total of 65 ethnoveterinary plants belonging to 38 families are used for the treatment of animal diseases. According to the local farmers, the most often mentioned species that used in the resarch area have high ethno-veterinary potential. Most of these plants are also used for some human conditions in the study area. There are large numbers of ethno-veterinary practices EVPs in southern Turkey with undocumented cumulative knowledge of the indigenous people. Unfortunately, some evidence of their slow disappearance has been found. The traditional knowledge in the treatment of livestock diseases of the Giresun districts needs further scientific evaluations by phytochemical and antimicrobial experimentation.

Process Biochemistry, 2021

Plants, 2021

Nepeta baytopii is a poorly studied, endemic Nepeta species (Lamiaceae) of Turkey. For the first ... more Nepeta baytopii is a poorly studied, endemic Nepeta species (Lamiaceae) of Turkey. For the first time, the biological activities (antioxidant, enzyme inhibition, and cytotoxicity properties) of the hexane, ethyl acetate, methanol, water/methanol, and water extracts and essential oil prepared from N. baytopii aerial parts were assessed. Hydro-methanol (41.25 mg gallic acid equivalent (GAE)/g) and water extracts (50.30 mg GAE/g), respectively showed the highest radical scavenging (94.40 and 129.22 mg Trolox equivalent (TE)/g, for 2,2-diphenyl-1-picrylhydrazyl radical and 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid radical scavenging assays) and reducing (229.37 and 129.55 mg TE/g, for ferric-reducing antioxidant power and cupric-reducing antioxidant capacity assays) capacities in vitro. An interestingly high inhibition was observed for ethyl acetate extract against butyrylcholinesterase (10.85 mg galantamine equivalent/g). The methanol extract showed high cytotoxicity (31.7%...

Edremit Korfezi, Biga yarimadasinin guneyinde konumlanmis onemli turizm merkezlerini ve Kazdaglar... more Edremit Korfezi, Biga yarimadasinin guneyinde konumlanmis onemli turizm merkezlerini ve Kazdaglarini (Ida) iceren bir korfezdir. Korfez, cografik olarak Ege Bolgesinin kuzeyini olusturmakla beraber, Canakkale ve Balikesir illerinin kiyilarindadir. Bu calismada Balikesir’in Edremit, Havran, Burhaniye ilcelerine bagli 21 koy gezilmis ve ari yetistiriciligi yapan 80 kisi ile gorusulmustur. Ari yetistiricilerinin kovanlarini biraktiklari yerlerde arilarin bal yapmak icin en fazla kondugu bitkiler hem ari yetistiricilerine sorulmus hem de arazide flora calismasi yapilarak tespit edilmistir. Sonuc olarak arilarin en fazla kondugu 34 bitki taksonu belirlenerek bal arilarinin en fazla ziyaret ettigi bitkilerin Asteraceae, Boraginaceae, Fabaceae, Lamiaceae ve Cistaceae familyalarina bagli taksonlar oldugu gorulmustur. Bu familyalardan ise bal arilarinin en cok, Echium plantagineum, Helianthus annuus, Origanum spp., Paliurus spina-christi, Vitex agnus-castus, Cistus spp., Trifolium spp. ve Ce...

Bu calisma, 2007-2009 yillari arasinda Havran ve Burhaniye (Balikesir) yorelerinde gerceklestiril... more Bu calisma, 2007-2009 yillari arasinda Havran ve Burhaniye (Balikesir) yorelerinde gerceklestirilen tarimsal biyocesitlilik arastirmalari kapsaminda, ekimi yapilan zeytin cesitleri ile bunlarin kullanim alanlarini belirlemek amaciyla yapilmistir. Burhaniye ve Havran ilceleri; Kazdaglari ve Madra dagi arasindaki ovada yer alan ve tarim arazilerinin buyuk kismi zeytinliklerle kapli olan yerlesim birimleridir. Arastirma kapsaminda yorede 21 yerlesim birimi ve 8 yerel pazarda calismalar yapilmistir. Bu sure icinde arastirma alaninda 135 kisiyle sozlu gorusme yapilmistir. Ayrica yoredeki zeytin fabrikalari ve ilce tarim mudurluklerinde incelemelerde bulunulmustur. Arastirma sonunda, bolgede kullanimi belirlenen zeytin ve zeytin urunlerine ait yerel bilgiler toplanmistir. Zeytin bitkisinin gida olarak kullanimi basta olmak uzere, tibbi kullanim, el sanatlari, sabun yapimi, hayvan yemi, yakacak vb. bircok alanda kullanildigi belirlenmistir. Zeytin ve zeytinden elde edilen toplam 21 farkli ...

In this study, potential plant taxa with invasive character that spread in Bingol (Center) and su... more In this study, potential plant taxa with invasive character that spread in Bingol (Center) and surrounding areas were determined and EUNIS Habitat types were revealed according to the environment in which these taxa live. In addition, an invasive species inventory has been created in based on literature carried out in Bingol province As a result of the research; It has been observed that 107 genera and 158 taxa belonging to 27 families that spread in Bingol (Center) and surrounding areas can be included in the potential plants class with invasive characteristics. Among these, the families with the most taxa are; Fabaceae (36 taxa, 22.8%), Asteraceae (34 taxa, 21.5%) and Poaceae (26 taxa, 16.5%). The most taxa containing genera; Trifolium L. (15 taxa, 9.5%) followed by Centaurea L. Lathyrus L. Poa L. and Vicia L. with 4 taxa each, respectively. During the study, 11 different EUNIS habitat types where invasive taxa spread were identified. In the distribution of taxa according to EUNIS...

Phytochemical investigation of Stenotaenia macrocarpa Freyn & Sint. (Apiaceae) led to the isolati... more Phytochemical investigation of Stenotaenia macrocarpa Freyn & Sint. (Apiaceae) led to the isolation of ten known compounds: eight flavonoids (1–8) and two furanocoumarins (9–10). The chemical structures of the compounds were elucidated based on 1D and 2D NMR and MS spectra, as well as comparison with the relevant literature data. To the best of our knowledge, this is the first detailed phytochemical study about Stenotaenia macrocarpa and the first report on the isolation of all the compounds from the genus Stenotaenia, and manghaslin (2) and its methoxylated derivative typhaneoside (3) from Apiaceae. The chemotaxonomic significance of isolates was also discussed.

This study aims to record accumulation of knowledge on plants which are used as food by local peo... more This study aims to record accumulation of knowledge on plants which are used as food by local people of Elazog that has a rich culture and a very natural environment. Field study was carried out over a period of approximately two years (2010-2011). During this period, 92 vascular plant specimens were collected. The plants were pressed in the field and prepared for identification. A total of 62 food plants belonging to 28 families were identified in the region. There is no detailed information in the literature with regard to the use of brevipes for human nutrition. It is certained that wild plants being used for nutritional purposes by human beings are also used for medicinal purposes. Highlighting the importance of flora and ethnobotanical inventory studies in terms of the protection and use of plant sources, what is required is the cultivation of endangered plant species, establishment of seedbanks for these plants, recording of their natural habitat as well as conducting studies ...

Ethnobotany is a preliminary method of research, suitable for gathering information on the nutrit... more Ethnobotany is a preliminary method of research, suitable for gathering information on the nutritional use of plants. This paper aims to present the ethnobotanical field research data on food plants used in Manyas region. It provides a general perspective on their significance in past and present Manyas, and examines the concept of wild edible plants as medicinal plants. The information about the use of wild edible plants was collected from 4 different open-air-markets and 14 villages in the city over a period of two years (2009-2011), through unstructured interviews. In this study, a total of 58 wild food plant taxa belonging to 25 families were established and also plant parts used, ethnographic data related to vernacular names, traditional use were recorded. Family Lamiaceae is represented by the highest number of taxa (10), followed by Astaraceae (7), Rosaceae (6), Apiaceae (5). The most commonly used species in the region are Apium graveolens L. (kereviz), Oenanthe pimpinelloid...

Türk Doğa ve Fen Dergisi, 2020

Process Biochemistry, 2021

Abstract This study focused on the biological evaluation and chemical characterization of Centaur... more Abstract This study focused on the biological evaluation and chemical characterization of Centaurea bingoelensis, an endemic plant to Turkey. Different solvent extracts (hexane, dichloromethane (DCM), ethyl acetate (EA), methanol, hydro-methanol, and water extracts) were prepared. The antioxidant, enzyme inhibitory, antimicrobial and cytotoxic activities were investigated. The hydro-methanol extract, possessing high phenolic content (41.57 mg gallic acid equivalent (GAE)/g extract), showed highest reducing capacity (136.87 and 82.16 mg Trolox equivalent[TE]/g extract, for cupric reducing antioxidant capacity and ferric reducing antioxidant power, respectively) and radical scavenging potential (70.72 and 76.53 mg TE/g extract, against 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), respectively). Ultra performance liquid chromatography - tandem mass spectrometer (UHPLC/MS/MS) analysis revealed the presence of 67 and 62 compounds in the methanolic and water extracts, respectively. According to the broth microdilution results, DCM and EA extracts showed significant antimicrobial activity with Sarcina lutea being the most sensitive bacterium to the extracts (MIC = 0.19 (DCM) and 0.097 mg/mL (EA)). Most extracts showed promising antifungal activity against Candida albicans. The methanol extract was most toxic against human hepatocarcinoma (HepG2) cells, and also significantly reduced the cell viability of the non-tumoral murine bone marrow stromal (S17) cells. This study has provided valuable scientific data on this endemic plant which can be considered as a promising candidate for the development of novel phyto-pharmaceuticals.

Türk Doğa ve Fen Dergisi, 2020

Türk Doğa ve Fen Dergisi, 2020

Öz: Bingöl ili ülkemizin önemli arıcılık merkezlerinden biridir. Bu çalışmada; Solhan (Bingöl) yö... more Öz: Bingöl ili ülkemizin önemli arıcılık merkezlerinden biridir. Bu çalışmada; Solhan (Bingöl) yöresinde gerçekleştirilen arazi çalışmaları kapsamında arı konaklama alanları ve çevre alanlarda çok sayıda arazi gezisi düzenlenmiştir. Bu kapsamda arazide yapılan yoğun gözlemler ve bölgede arıcılık yapan kişilerle uygulanan anketler ışığında arıların nektar, polen ve diğer arı ürünleri için kaynak olarak kullandığı bitkiler kayıt altına alınmıştır. Araştırmalar sonucunda Solhan yöresinde arıcılık açısından önemli potansiyele sahip 25 bitki familyasına ait 100 bitki taksonu tespit edilmiştir. Bu taksonlardan 7'si endemiktir. En fazla taksona sahip familyalar; Asteraceae (31), Lamiaceae (15), Fabaceae (15), Rosaceae (4), Caprifoliaceae (3), Caryophyllaceae (3), Hypericaceae (3), Asparagaceae (2) şeklindedir. Ayrıca çalışmalar kapsamında arı bitkileri üzerine yapılan palinolojik değerlendirmelerle önemli bazı taksonların polen atlası hazırlanmıştır.

Industrial Crops and Products, 2020

Abstract Several Cirsium species have been used in folk medicine for the management of human ailm... more Abstract Several Cirsium species have been used in folk medicine for the management of human ailments. However, there is a paucity of scientific data regarding their biological activity as in the case of the new species, C. yildizianum, from Anatolia, Turkey. The present study endeavours for the first time to appraise the antioxidant and enzyme inhibitory activity of C. yildizianum. The phytochemical profiles of C. yildizianum extracts obtained using homogeniser-assisted extraction (HAE), ultrasound-assisted extraction (UAE), Soxhlet extraction, maceration, decoction, and infusion, using methanol or water as extraction solvents, was determined by high-performance liquid chromatography with electrospray ionization mass spectrometric detection (HPLC–ESI-MSn) analysis. In all extracts, flavonoids were the most abundant compounds, particularly luteolin and apigenin glycosides. HAE methanol extract presented the highest phenolic (37.10 mg gallic acid equivalent/g) and flavonoid (46.78 mg rutin equivalent/g) contents. Likewise, HAE-methanol extract showed potent radical scavenging (40.76 and 68.13 mg Trolox equivalent [TE]/g, for DPPH and ABTS, respectively) and reducing properties (127.62 and 89.95 mg TE/g, for CUPRAC and FRAP, respectively). HAE-methanol extract showed inhibitory activity against acetylcholinesterase (AChE) (3.57 mg galantamine equivalent [GALAE]/g). UAE-methanol extract was a potent inhibitor of butrylcholinesterase (BChE) (2.72 mg GALAE/g) and tyrosinase (121.06 mg kojic acid equivalent/g) However, poor inhibition was recorded for enzymes targeted in the management of diabetes type II, namely α-amylase and α-glucosidase. On the other hand, potent metal chelating property was observed for water extracts. This study provides comprehensive scientific information on the phytochemical profile of C. yildizianum extracted using different procedures and extraction solvents, which might be considered as valuable baseline data for future bioproducts development.

Bangladesh Journal of Plant Taxonomy, 2019

Micromorphology and anatomy of six Onosma L. species, viz. O. argentata Hub.-Mor., O. neglecta Ri... more Micromorphology and anatomy of six Onosma L. species, viz. O. argentata Hub.-Mor., O. neglecta Riedl, O. proballanthera Rech. f., O. rechingeri Riedl, O. sericea Willd. and O. stenoloba Hausskn. ex Riedl from Turky were investigated. Stem anatomy revealed that cuticle layer ranged from 0.6 µm in O. argentata to 1.7 µm in O. proballanthera. Parenchymatous cells of O. neglecta and O. stenoloba possessed more intense starch than the other species studied. In leaf anatomy, the longest palisade parenchyma was found in O. neglecta, while the smallest was noted in O. argentata. Mesophyll structure of O. argentata, O. sericea and O. rechingeri was equifacial (isobilateral), while O. neglecta, O. proballanthera and O. stenoloba presented bifacial (dorsiventral) structure. Rugose nutlet ornamentation was observed in O. argentata, O. neglecta and O. sericea, whereas reticulate type was found in O. proballanthera, O. rechingeri and O. stenoloba. Onosma stenoloba could easily be distinguished fr...

Journal of Herbal Medicine, 2018

Abstract This paper illustrates the result of an ethnobotanical study carried out in the Bingol r... more Abstract This paper illustrates the result of an ethnobotanical study carried out in the Bingol region of Turkey. The aim of this study was to document the medicinal uses of plants in the district of Bingol province. The ethnobotanical results contain quantitative information on the diversity of medicinal plants documented in the region. This study, conducted between 2010 and 2012, gathered information on the medicinal plant species traditionally used in Bingol, Turkey and the local names of these plants. In the scope of the study, medicinal plant species and related information was collected; herbarium materials were prepared; and the specimens were labelled. The information was collected through semi-structured interviews, questionnaires and personal observations. Results were analysed using quantitative indices of information consent factor (ICF/FIC), fidelity level (FL) and use value (UV). A total of 93 medical plants belonging to 38 families were identified in the region. Among these, 80 species grew wild and 13 species were cultivated. The most common medicinal plant families were Asteraceae (14), Rosaceae (12), Lamiaceae (10) and Apiaceae (7). The most common preparations were infusion and decoction. A total of 220 medicinal uses (remedies) were recorded. The use of traditional medicine was still widespread among the people in Bingol. However, due to the increasing health service facilities in the area, herbal medicine seemed to be more related to health care and disease prevention than cure. There is a gradual loss of traditional knowledge regarding the use of medicinal plants by the younger generations.

Biyolojik Çeşitlilik ve Koruma, Dec 15, 2016

South African Journal of Botany, 2021

Abstract The lack of ethnoveterinary surveys in Turkey, results in losses in the veterinary phyto... more Abstract The lack of ethnoveterinary surveys in Turkey, results in losses in the veterinary phytopharmacology field. This is the first ethnoveterinary research in which statistical calculations about plants are done by informant consensus factor (ICF) method in the Blacksea Region of Turkey. To catalog, analyze, and disseminate the knowledge of plant use in ethnoveterinary practices in the province of Giresun (Turkey). Information was gathered through open and semi-structured interviews with local people, mainly elderly shepherds and farmers, in the Giresun province. The collected data was analyzed quantitatively using two indices, informant consensus factor (ICF). A total of 65 ethnoveterinary plants belonging to 38 families are used for the treatment of animal diseases. According to the local farmers, the most often mentioned species that used in the resarch area have high ethno-veterinary potential. Most of these plants are also used for some human conditions in the study area. There are large numbers of ethno-veterinary practices EVPs in southern Turkey with undocumented cumulative knowledge of the indigenous people. Unfortunately, some evidence of their slow disappearance has been found. The traditional knowledge in the treatment of livestock diseases of the Giresun districts needs further scientific evaluations by phytochemical and antimicrobial experimentation.

Process Biochemistry, 2021

Plants, 2021

Nepeta baytopii is a poorly studied, endemic Nepeta species (Lamiaceae) of Turkey. For the first ... more Nepeta baytopii is a poorly studied, endemic Nepeta species (Lamiaceae) of Turkey. For the first time, the biological activities (antioxidant, enzyme inhibition, and cytotoxicity properties) of the hexane, ethyl acetate, methanol, water/methanol, and water extracts and essential oil prepared from N. baytopii aerial parts were assessed. Hydro-methanol (41.25 mg gallic acid equivalent (GAE)/g) and water extracts (50.30 mg GAE/g), respectively showed the highest radical scavenging (94.40 and 129.22 mg Trolox equivalent (TE)/g, for 2,2-diphenyl-1-picrylhydrazyl radical and 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid radical scavenging assays) and reducing (229.37 and 129.55 mg TE/g, for ferric-reducing antioxidant power and cupric-reducing antioxidant capacity assays) capacities in vitro. An interestingly high inhibition was observed for ethyl acetate extract against butyrylcholinesterase (10.85 mg galantamine equivalent/g). The methanol extract showed high cytotoxicity (31.7%...

Edremit Korfezi, Biga yarimadasinin guneyinde konumlanmis onemli turizm merkezlerini ve Kazdaglar... more Edremit Korfezi, Biga yarimadasinin guneyinde konumlanmis onemli turizm merkezlerini ve Kazdaglarini (Ida) iceren bir korfezdir. Korfez, cografik olarak Ege Bolgesinin kuzeyini olusturmakla beraber, Canakkale ve Balikesir illerinin kiyilarindadir. Bu calismada Balikesir’in Edremit, Havran, Burhaniye ilcelerine bagli 21 koy gezilmis ve ari yetistiriciligi yapan 80 kisi ile gorusulmustur. Ari yetistiricilerinin kovanlarini biraktiklari yerlerde arilarin bal yapmak icin en fazla kondugu bitkiler hem ari yetistiricilerine sorulmus hem de arazide flora calismasi yapilarak tespit edilmistir. Sonuc olarak arilarin en fazla kondugu 34 bitki taksonu belirlenerek bal arilarinin en fazla ziyaret ettigi bitkilerin Asteraceae, Boraginaceae, Fabaceae, Lamiaceae ve Cistaceae familyalarina bagli taksonlar oldugu gorulmustur. Bu familyalardan ise bal arilarinin en cok, Echium plantagineum, Helianthus annuus, Origanum spp., Paliurus spina-christi, Vitex agnus-castus, Cistus spp., Trifolium spp. ve Ce...

Bu calisma, 2007-2009 yillari arasinda Havran ve Burhaniye (Balikesir) yorelerinde gerceklestiril... more Bu calisma, 2007-2009 yillari arasinda Havran ve Burhaniye (Balikesir) yorelerinde gerceklestirilen tarimsal biyocesitlilik arastirmalari kapsaminda, ekimi yapilan zeytin cesitleri ile bunlarin kullanim alanlarini belirlemek amaciyla yapilmistir. Burhaniye ve Havran ilceleri; Kazdaglari ve Madra dagi arasindaki ovada yer alan ve tarim arazilerinin buyuk kismi zeytinliklerle kapli olan yerlesim birimleridir. Arastirma kapsaminda yorede 21 yerlesim birimi ve 8 yerel pazarda calismalar yapilmistir. Bu sure icinde arastirma alaninda 135 kisiyle sozlu gorusme yapilmistir. Ayrica yoredeki zeytin fabrikalari ve ilce tarim mudurluklerinde incelemelerde bulunulmustur. Arastirma sonunda, bolgede kullanimi belirlenen zeytin ve zeytin urunlerine ait yerel bilgiler toplanmistir. Zeytin bitkisinin gida olarak kullanimi basta olmak uzere, tibbi kullanim, el sanatlari, sabun yapimi, hayvan yemi, yakacak vb. bircok alanda kullanildigi belirlenmistir. Zeytin ve zeytinden elde edilen toplam 21 farkli ...

In this study, potential plant taxa with invasive character that spread in Bingol (Center) and su... more In this study, potential plant taxa with invasive character that spread in Bingol (Center) and surrounding areas were determined and EUNIS Habitat types were revealed according to the environment in which these taxa live. In addition, an invasive species inventory has been created in based on literature carried out in Bingol province As a result of the research; It has been observed that 107 genera and 158 taxa belonging to 27 families that spread in Bingol (Center) and surrounding areas can be included in the potential plants class with invasive characteristics. Among these, the families with the most taxa are; Fabaceae (36 taxa, 22.8%), Asteraceae (34 taxa, 21.5%) and Poaceae (26 taxa, 16.5%). The most taxa containing genera; Trifolium L. (15 taxa, 9.5%) followed by Centaurea L. Lathyrus L. Poa L. and Vicia L. with 4 taxa each, respectively. During the study, 11 different EUNIS habitat types where invasive taxa spread were identified. In the distribution of taxa according to EUNIS...

Phytochemical investigation of Stenotaenia macrocarpa Freyn & Sint. (Apiaceae) led to the isolati... more Phytochemical investigation of Stenotaenia macrocarpa Freyn & Sint. (Apiaceae) led to the isolation of ten known compounds: eight flavonoids (1–8) and two furanocoumarins (9–10). The chemical structures of the compounds were elucidated based on 1D and 2D NMR and MS spectra, as well as comparison with the relevant literature data. To the best of our knowledge, this is the first detailed phytochemical study about Stenotaenia macrocarpa and the first report on the isolation of all the compounds from the genus Stenotaenia, and manghaslin (2) and its methoxylated derivative typhaneoside (3) from Apiaceae. The chemotaxonomic significance of isolates was also discussed.

This study aims to record accumulation of knowledge on plants which are used as food by local peo... more This study aims to record accumulation of knowledge on plants which are used as food by local people of Elazog that has a rich culture and a very natural environment. Field study was carried out over a period of approximately two years (2010-2011). During this period, 92 vascular plant specimens were collected. The plants were pressed in the field and prepared for identification. A total of 62 food plants belonging to 28 families were identified in the region. There is no detailed information in the literature with regard to the use of brevipes for human nutrition. It is certained that wild plants being used for nutritional purposes by human beings are also used for medicinal purposes. Highlighting the importance of flora and ethnobotanical inventory studies in terms of the protection and use of plant sources, what is required is the cultivation of endangered plant species, establishment of seedbanks for these plants, recording of their natural habitat as well as conducting studies ...

Ethnobotany is a preliminary method of research, suitable for gathering information on the nutrit... more Ethnobotany is a preliminary method of research, suitable for gathering information on the nutritional use of plants. This paper aims to present the ethnobotanical field research data on food plants used in Manyas region. It provides a general perspective on their significance in past and present Manyas, and examines the concept of wild edible plants as medicinal plants. The information about the use of wild edible plants was collected from 4 different open-air-markets and 14 villages in the city over a period of two years (2009-2011), through unstructured interviews. In this study, a total of 58 wild food plant taxa belonging to 25 families were established and also plant parts used, ethnographic data related to vernacular names, traditional use were recorded. Family Lamiaceae is represented by the highest number of taxa (10), followed by Astaraceae (7), Rosaceae (6), Apiaceae (5). The most commonly used species in the region are Apium graveolens L. (kereviz), Oenanthe pimpinelloid...

Türk Doğa ve Fen Dergisi, 2020

Process Biochemistry, 2021

Abstract This study focused on the biological evaluation and chemical characterization of Centaur... more Abstract This study focused on the biological evaluation and chemical characterization of Centaurea bingoelensis, an endemic plant to Turkey. Different solvent extracts (hexane, dichloromethane (DCM), ethyl acetate (EA), methanol, hydro-methanol, and water extracts) were prepared. The antioxidant, enzyme inhibitory, antimicrobial and cytotoxic activities were investigated. The hydro-methanol extract, possessing high phenolic content (41.57 mg gallic acid equivalent (GAE)/g extract), showed highest reducing capacity (136.87 and 82.16 mg Trolox equivalent[TE]/g extract, for cupric reducing antioxidant capacity and ferric reducing antioxidant power, respectively) and radical scavenging potential (70.72 and 76.53 mg TE/g extract, against 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), respectively). Ultra performance liquid chromatography - tandem mass spectrometer (UHPLC/MS/MS) analysis revealed the presence of 67 and 62 compounds in the methanolic and water extracts, respectively. According to the broth microdilution results, DCM and EA extracts showed significant antimicrobial activity with Sarcina lutea being the most sensitive bacterium to the extracts (MIC = 0.19 (DCM) and 0.097 mg/mL (EA)). Most extracts showed promising antifungal activity against Candida albicans. The methanol extract was most toxic against human hepatocarcinoma (HepG2) cells, and also significantly reduced the cell viability of the non-tumoral murine bone marrow stromal (S17) cells. This study has provided valuable scientific data on this endemic plant which can be considered as a promising candidate for the development of novel phyto-pharmaceuticals.

Türk Doğa ve Fen Dergisi, 2020

Türk Doğa ve Fen Dergisi, 2020

Öz: Bingöl ili ülkemizin önemli arıcılık merkezlerinden biridir. Bu çalışmada; Solhan (Bingöl) yö... more Öz: Bingöl ili ülkemizin önemli arıcılık merkezlerinden biridir. Bu çalışmada; Solhan (Bingöl) yöresinde gerçekleştirilen arazi çalışmaları kapsamında arı konaklama alanları ve çevre alanlarda çok sayıda arazi gezisi düzenlenmiştir. Bu kapsamda arazide yapılan yoğun gözlemler ve bölgede arıcılık yapan kişilerle uygulanan anketler ışığında arıların nektar, polen ve diğer arı ürünleri için kaynak olarak kullandığı bitkiler kayıt altına alınmıştır. Araştırmalar sonucunda Solhan yöresinde arıcılık açısından önemli potansiyele sahip 25 bitki familyasına ait 100 bitki taksonu tespit edilmiştir. Bu taksonlardan 7'si endemiktir. En fazla taksona sahip familyalar; Asteraceae (31), Lamiaceae (15), Fabaceae (15), Rosaceae (4), Caprifoliaceae (3), Caryophyllaceae (3), Hypericaceae (3), Asparagaceae (2) şeklindedir. Ayrıca çalışmalar kapsamında arı bitkileri üzerine yapılan palinolojik değerlendirmelerle önemli bazı taksonların polen atlası hazırlanmıştır.

Industrial Crops and Products, 2020

Abstract Several Cirsium species have been used in folk medicine for the management of human ailm... more Abstract Several Cirsium species have been used in folk medicine for the management of human ailments. However, there is a paucity of scientific data regarding their biological activity as in the case of the new species, C. yildizianum, from Anatolia, Turkey. The present study endeavours for the first time to appraise the antioxidant and enzyme inhibitory activity of C. yildizianum. The phytochemical profiles of C. yildizianum extracts obtained using homogeniser-assisted extraction (HAE), ultrasound-assisted extraction (UAE), Soxhlet extraction, maceration, decoction, and infusion, using methanol or water as extraction solvents, was determined by high-performance liquid chromatography with electrospray ionization mass spectrometric detection (HPLC–ESI-MSn) analysis. In all extracts, flavonoids were the most abundant compounds, particularly luteolin and apigenin glycosides. HAE methanol extract presented the highest phenolic (37.10 mg gallic acid equivalent/g) and flavonoid (46.78 mg rutin equivalent/g) contents. Likewise, HAE-methanol extract showed potent radical scavenging (40.76 and 68.13 mg Trolox equivalent [TE]/g, for DPPH and ABTS, respectively) and reducing properties (127.62 and 89.95 mg TE/g, for CUPRAC and FRAP, respectively). HAE-methanol extract showed inhibitory activity against acetylcholinesterase (AChE) (3.57 mg galantamine equivalent [GALAE]/g). UAE-methanol extract was a potent inhibitor of butrylcholinesterase (BChE) (2.72 mg GALAE/g) and tyrosinase (121.06 mg kojic acid equivalent/g) However, poor inhibition was recorded for enzymes targeted in the management of diabetes type II, namely α-amylase and α-glucosidase. On the other hand, potent metal chelating property was observed for water extracts. This study provides comprehensive scientific information on the phytochemical profile of C. yildizianum extracted using different procedures and extraction solvents, which might be considered as valuable baseline data for future bioproducts development.

Bangladesh Journal of Plant Taxonomy, 2019

Micromorphology and anatomy of six Onosma L. species, viz. O. argentata Hub.-Mor., O. neglecta Ri... more Micromorphology and anatomy of six Onosma L. species, viz. O. argentata Hub.-Mor., O. neglecta Riedl, O. proballanthera Rech. f., O. rechingeri Riedl, O. sericea Willd. and O. stenoloba Hausskn. ex Riedl from Turky were investigated. Stem anatomy revealed that cuticle layer ranged from 0.6 µm in O. argentata to 1.7 µm in O. proballanthera. Parenchymatous cells of O. neglecta and O. stenoloba possessed more intense starch than the other species studied. In leaf anatomy, the longest palisade parenchyma was found in O. neglecta, while the smallest was noted in O. argentata. Mesophyll structure of O. argentata, O. sericea and O. rechingeri was equifacial (isobilateral), while O. neglecta, O. proballanthera and O. stenoloba presented bifacial (dorsiventral) structure. Rugose nutlet ornamentation was observed in O. argentata, O. neglecta and O. sericea, whereas reticulate type was found in O. proballanthera, O. rechingeri and O. stenoloba. Onosma stenoloba could easily be distinguished fr...

Journal of Herbal Medicine, 2018

Abstract This paper illustrates the result of an ethnobotanical study carried out in the Bingol r... more Abstract This paper illustrates the result of an ethnobotanical study carried out in the Bingol region of Turkey. The aim of this study was to document the medicinal uses of plants in the district of Bingol province. The ethnobotanical results contain quantitative information on the diversity of medicinal plants documented in the region. This study, conducted between 2010 and 2012, gathered information on the medicinal plant species traditionally used in Bingol, Turkey and the local names of these plants. In the scope of the study, medicinal plant species and related information was collected; herbarium materials were prepared; and the specimens were labelled. The information was collected through semi-structured interviews, questionnaires and personal observations. Results were analysed using quantitative indices of information consent factor (ICF/FIC), fidelity level (FL) and use value (UV). A total of 93 medical plants belonging to 38 families were identified in the region. Among these, 80 species grew wild and 13 species were cultivated. The most common medicinal plant families were Asteraceae (14), Rosaceae (12), Lamiaceae (10) and Apiaceae (7). The most common preparations were infusion and decoction. A total of 220 medicinal uses (remedies) were recorded. The use of traditional medicine was still widespread among the people in Bingol. However, due to the increasing health service facilities in the area, herbal medicine seemed to be more related to health care and disease prevention than cure. There is a gradual loss of traditional knowledge regarding the use of medicinal plants by the younger generations.