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Research paper thumbnail of Effect of acarbose on glycemic control, serum lipids and lipoproteins in type 2 diabetes

JPMA. The Journal of …, 2000

OBJECTIVE: To assess the efficacy of acarbose monotherapy during 12-weeks treatment on the fastin... more OBJECTIVE: To assess the efficacy of acarbose monotherapy during 12-weeks treatment on the fasting glycemic level, lipid and lipoproteins profiles, in patients with type 2 diabetes mellitus. SETTING: Type 2 diabetics were selected from out patient department of Baqai ...

Research paper thumbnail of Evaluation of combined effect of verapamil and ranitidine on the volume and acidity of carbachol induced gastric secretion

Journal of Ayub Medical College

This study was conducted to observe the effect of H2-receptor antagonist Ranitidine and calcium c... more This study was conducted to observe the effect of H2-receptor antagonist Ranitidine and calcium channel blocker Verapamil on the volume, free and total acidity of carbachol induced gastric secretion. Twenty four albino rats of Sprangue Dawley strain weighing 150-200 grams were used. Animals were divided into Four groups. After fasting for 48 hours, pylorus of each animal was ligated, verapamil 10 mg/Kg, ranitidine 0.5 mg/Kg and carbachol 600 microg/Kg body weight were administered intraperitoneally. It was observed that ranitidine significantly reduced both the volume and acidity (p<0.001). Similarly Verapamil also significantly reduced the volume, free and total acidity when compared to carbachol alone. When verapamil was used in combination with ranitidine 15 minutes before carbachol, there was further inhibition of volume and acidity as compared to ranitidine alone. This reduction was statistically highly significant (p<0.001). Our study suggests that combined therapy of ve...

Research paper thumbnail of Neonatal factors predisposing to atopy

Journal of the College of Physicians and Surgeons, 2005

Research paper thumbnail of Neonatal factors predisposing to atopy

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2005

Research paper thumbnail of Evaluation of combined effect of verapamil and ranitidine on the volume and acidity of carbachol induced gastric secretion

Journal of Ayub Medical College, Abbottabad : JAMC, 2004

BACKGROUND This study was conducted to observe the effect of H2-receptor antagonist Ranitidine an... more BACKGROUND This study was conducted to observe the effect of H2-receptor antagonist Ranitidine and calcium channel blocker Verapamil on the volume, free and total acidity of carbachol induced gastric secretion. METHODS Twenty four albino rats of Sprangue Dawley strain weighing 150-200 grams were used. Animals were divided into Four groups. After fasting for 48 hours, pylorus of each animal was ligated, verapamil 10 mg/Kg, ranitidine 0.5 mg/Kg and carbachol 600 microg/Kg body weight were administered intraperitoneally. RESULTS It was observed that ranitidine significantly reduced both the volume and acidity (p<0.001). Similarly Verapamil also significantly reduced the volume, free and total acidity when compared to carbachol alone. When verapamil was used in combination with ranitidine 15 minutes before carbachol, there was further inhibition of volume and acidity as compared to ranitidine alone. This reduction was statistically highly significant (p<0.001). CONCLUSION Our stud...

Research paper thumbnail of Balanced Diet

Objective: Non-pharmacological intervention to manage the health by healthybalanced diet and life... more Objective: Non-pharmacological intervention to manage the health by healthybalanced diet and life style modifications. Study Design: Randomized Cross sectional Study.Place & Duration: Pakistan Council of Scientific and Industrial Research (PCSIR) laboratoryKarachi from March 2012 to June 2013. Material & Methods: In this study, 210 volunteers wereincluded (137 male and 73 female) aged between 25-60 years. The study was conducted withthe questionnaire being filled at PCSIR labs, Karachi. The study period included from March toMay 2012. One year later the same group of volunteers were re-examined from March to June2013, who managed to alter the diet and life style for one year. The questionnaire was filled by anexpert well versed in collecting the data from the patients who attended the OPD at PCSIR labs.Results: The results indicate that a lot of people in our population lead a sedentary life styleand do not take part in physical activity which leads to health problems due to compara...

Research paper thumbnail of Balanced Diet; Balanced Life

The Professional Medical Journal, 2015

Research paper thumbnail of Neonatal factors predisposing to atopy

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2005

Research paper thumbnail of Evaluation of combined effect of verapamil and ranitidine on the volume and acidity of carbachol induced gastric secretion

Journal of Ayub Medical College, Abbottabad : JAMC

This study was conducted to observe the effect of H2-receptor antagonist Ranitidine and calcium c... more This study was conducted to observe the effect of H2-receptor antagonist Ranitidine and calcium channel blocker Verapamil on the volume, free and total acidity of carbachol induced gastric secretion. Twenty four albino rats of Sprangue Dawley strain weighing 150-200 grams were used. Animals were divided into Four groups. After fasting for 48 hours, pylorus of each animal was ligated, verapamil 10 mg/Kg, ranitidine 0.5 mg/Kg and carbachol 600 microg/Kg body weight were administered intraperitoneally. It was observed that ranitidine significantly reduced both the volume and acidity (p<0.001). Similarly Verapamil also significantly reduced the volume, free and total acidity when compared to carbachol alone. When verapamil was used in combination with ranitidine 15 minutes before carbachol, there was further inhibition of volume and acidity as compared to ranitidine alone. This reduction was statistically highly significant (p<0.001). Our study suggests that combined therapy of ve...

Research paper thumbnail of Basic Pharmacology Drugs

Research paper thumbnail of Effect of acarbose on glycemic control, serum lipids and lipoproteins in type 2 diabetes

JPMA. The Journal of …, 2000

OBJECTIVE: To assess the efficacy of acarbose monotherapy during 12-weeks treatment on the fastin... more OBJECTIVE: To assess the efficacy of acarbose monotherapy during 12-weeks treatment on the fasting glycemic level, lipid and lipoproteins profiles, in patients with type 2 diabetes mellitus. SETTING: Type 2 diabetics were selected from out patient department of Baqai ...

Research paper thumbnail of Evaluation of combined effect of verapamil and ranitidine on the volume and acidity of carbachol induced gastric secretion

Journal of Ayub Medical College

This study was conducted to observe the effect of H2-receptor antagonist Ranitidine and calcium c... more This study was conducted to observe the effect of H2-receptor antagonist Ranitidine and calcium channel blocker Verapamil on the volume, free and total acidity of carbachol induced gastric secretion. Twenty four albino rats of Sprangue Dawley strain weighing 150-200 grams were used. Animals were divided into Four groups. After fasting for 48 hours, pylorus of each animal was ligated, verapamil 10 mg/Kg, ranitidine 0.5 mg/Kg and carbachol 600 microg/Kg body weight were administered intraperitoneally. It was observed that ranitidine significantly reduced both the volume and acidity (p<0.001). Similarly Verapamil also significantly reduced the volume, free and total acidity when compared to carbachol alone. When verapamil was used in combination with ranitidine 15 minutes before carbachol, there was further inhibition of volume and acidity as compared to ranitidine alone. This reduction was statistically highly significant (p<0.001). Our study suggests that combined therapy of ve...

Research paper thumbnail of Neonatal factors predisposing to atopy

Journal of the College of Physicians and Surgeons, 2005

Research paper thumbnail of Neonatal factors predisposing to atopy

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2005

Research paper thumbnail of Evaluation of combined effect of verapamil and ranitidine on the volume and acidity of carbachol induced gastric secretion

Journal of Ayub Medical College, Abbottabad : JAMC, 2004

BACKGROUND This study was conducted to observe the effect of H2-receptor antagonist Ranitidine an... more BACKGROUND This study was conducted to observe the effect of H2-receptor antagonist Ranitidine and calcium channel blocker Verapamil on the volume, free and total acidity of carbachol induced gastric secretion. METHODS Twenty four albino rats of Sprangue Dawley strain weighing 150-200 grams were used. Animals were divided into Four groups. After fasting for 48 hours, pylorus of each animal was ligated, verapamil 10 mg/Kg, ranitidine 0.5 mg/Kg and carbachol 600 microg/Kg body weight were administered intraperitoneally. RESULTS It was observed that ranitidine significantly reduced both the volume and acidity (p<0.001). Similarly Verapamil also significantly reduced the volume, free and total acidity when compared to carbachol alone. When verapamil was used in combination with ranitidine 15 minutes before carbachol, there was further inhibition of volume and acidity as compared to ranitidine alone. This reduction was statistically highly significant (p<0.001). CONCLUSION Our stud...

Research paper thumbnail of Balanced Diet

Objective: Non-pharmacological intervention to manage the health by healthybalanced diet and life... more Objective: Non-pharmacological intervention to manage the health by healthybalanced diet and life style modifications. Study Design: Randomized Cross sectional Study.Place & Duration: Pakistan Council of Scientific and Industrial Research (PCSIR) laboratoryKarachi from March 2012 to June 2013. Material & Methods: In this study, 210 volunteers wereincluded (137 male and 73 female) aged between 25-60 years. The study was conducted withthe questionnaire being filled at PCSIR labs, Karachi. The study period included from March toMay 2012. One year later the same group of volunteers were re-examined from March to June2013, who managed to alter the diet and life style for one year. The questionnaire was filled by anexpert well versed in collecting the data from the patients who attended the OPD at PCSIR labs.Results: The results indicate that a lot of people in our population lead a sedentary life styleand do not take part in physical activity which leads to health problems due to compara...

Research paper thumbnail of Balanced Diet; Balanced Life

The Professional Medical Journal, 2015

Research paper thumbnail of Neonatal factors predisposing to atopy

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2005

Research paper thumbnail of Evaluation of combined effect of verapamil and ranitidine on the volume and acidity of carbachol induced gastric secretion

Journal of Ayub Medical College, Abbottabad : JAMC

This study was conducted to observe the effect of H2-receptor antagonist Ranitidine and calcium c... more This study was conducted to observe the effect of H2-receptor antagonist Ranitidine and calcium channel blocker Verapamil on the volume, free and total acidity of carbachol induced gastric secretion. Twenty four albino rats of Sprangue Dawley strain weighing 150-200 grams were used. Animals were divided into Four groups. After fasting for 48 hours, pylorus of each animal was ligated, verapamil 10 mg/Kg, ranitidine 0.5 mg/Kg and carbachol 600 microg/Kg body weight were administered intraperitoneally. It was observed that ranitidine significantly reduced both the volume and acidity (p<0.001). Similarly Verapamil also significantly reduced the volume, free and total acidity when compared to carbachol alone. When verapamil was used in combination with ranitidine 15 minutes before carbachol, there was further inhibition of volume and acidity as compared to ranitidine alone. This reduction was statistically highly significant (p<0.001). Our study suggests that combined therapy of ve...

Research paper thumbnail of Basic Pharmacology Drugs