mahmoud rezaei - Academia.edu (original) (raw)
Papers by mahmoud rezaei
Background: Nowadays, anesthetic drugs are widely used in anesthesia and surgical procedures and ... more Background: Nowadays, anesthetic drugs are widely used in anesthesia and surgical procedures and their effects on memory have been the focus of attention for a very long time. The effects of these common drugs include Dexmedetomidine (DEX) and Etomidate (ETO), on memory are controversial. In this study, the effects of these two drugs, co-administrated with heights stress, were evaluated on short-term and long-term spatial memory. 48 male mice were divided into 6 experimental groups consisting of Control, Control+heightstress (H.S), ETO, ETO+H.S, DEX+H.S. Drugs were administered Intra-peritoneal with doses of 0.3-0.4 mg/kg and 11 mg/kg for DEX and ETO respectively, and spatial memory was assessed using the Barnes Model. Results: DEX improved acquisition and retention of spatial reference memory, whereas ETO showed no such effects. In addition, DEX and ETO showed excitatory effects on short-term spatial memory, however DEX was more effective than ETO. Conclusion: the results suggested the neuoprotective, synaptic plasticity and memory improving effects of DEX on spatial reference and working memory. However, the precise neuronal and molecular mechanisms of these effects and their relation to the anti-stress system is still unknown and requires further research. Background: Anesthetic drugs are widely used in anesthesia and surgical procedures and their effects on memory have been the focus of attention for a very long time. The experience of height stress may result in stressrelated psychiatric disorders such as Post-traumatic stress disorder (PTSD). Which is a psychiatric disease that occurs after serious accidents, anxiety and fright(1). The symptoms of PTSD include increased sensitivity to stress, intrusive memory, hyperarousal, and avoidance (1, 2). During recent years, improvement of behavioral tasks which assess spatial learning and memory in rodents has us comprehend the role of the hippocampus in these cognitive functions (3). Allocentric navigation involves different parts such as the hippocampus, entorhinal cortex, and its surrounding structures while in the human body this system encodes allocentric, semantic, and episodic memory. This form of memory is assessed in laboratory animals in many ways, but one form of assessment is the Barnes maze (4). The primary aim of the pharmacotherapeutic agents for PTSD is to disrupt the memory consolidation and the associated fear conditioning response after exposure to an event (5, 6). The risk of PTSD occurrence in patients exposed to stressful medical conditions associated with perioperative awareness or Intensive Care Unit (ICU) treatment is moderately high (7-9). Patients treated in ICU for life-threatening medical events have multiple traumatic experiences and often develop severe
Journal of Chest Surgery, 2021
Background: Subclavian vein (SV) catheterization is a method for the delivery of fluids, drugs, a... more Background: Subclavian vein (SV) catheterization is a method for the delivery of fluids, drugs, and blood products, venous blood sampling, and central vein pressure monitoring in cardiac surgery. Catheter occlusion is a serious complication of SV catheterization during cardiac surgery, especially after sternal retractor expansion. Methods: In this observational study, 303 patients who had successful right infraclavicular SV catheterization from September 2019 to April 2020 were enrolled to determine the incidence of catheter occlusion. After catheterization, the lumens of all catheters were checked for the ability to infuse and withdraw blood from the catheter before and after sternal retractor expansion. The patients' characteristics, cannulation approach, on-pump or off-pump technique, occlusion of the catheter and its lumens, and any associated complications were recorded. The data were analyzed using IBM SPSS ver. 22.0 (IBM Corp., Armonk, NY, USA). Results: Of the 303 patients studied, 205 were male (67.7%) and 98 were female (32.3%). Catheter occlusion occurred in 11 patients with on-pump cardiopulmonary bypass (CPB) (227 patients) and 4 patients with off-pump CPB (76 patients) (p=0.863). The incidence of catheter occlusion was 4.95% (15 of 303 patients) with no cases of simultaneous 3-lumen occlusion in a catheter. The most commonly occluded lumen was the distal lumen (57.92%). Simultaneous 2-lumen occlusion occurred in 4 patients. Catheter occlusion was found in 3 of 13 malpositioned catheters (23.07%). Conclusion: The current study showed that malpositioning of the catheter tip was a risk factor for catheter occlusion and that the distal lumen of a triple-lumen catheter was the most commonly occluded lumen.
Brazilian Journal of Anesthesiology (English Edition), 2021
Phenylketonuria is a rare disorder that increases the levels of phenylalanine in the blood. As th... more Phenylketonuria is a rare disorder that increases the levels of phenylalanine in the blood. As there are scant articles about anesthesia management in phenylketonuria patients, this encouraged us to report a short-time anesthesia management of a child with phenylketonuria for bone fracture. The anesthesia was induced with intravenous ketamine and midazolam. During procedure, he received 100% oxygen via a face mask throughout spontaneous breathing. The operation was uneventful, and he was completely awakened in the recovery room. This report emphasizes that in some situations, the combination of midazolam with ketamine could be used safely for short time anesthesia in phenylketonuria patients.
Journal of Research in Urology, 2019
Background & Objective: Satisfaction is one of the health aspects of human. Without attention to ... more Background & Objective: Satisfaction is one of the health aspects of human. Without attention to people's satisfaction in the health services, the health system act contrary to its mission. The aim of this study is to evaluate the patient's satisfaction in the urology ward at Shahid Beheshti Hospital in Hamadan University of Medical Sciences in second half of 2018, for investigating the strengths and weaknesses with provide guidance and better quality treatments. Methods: In this cross-sectional study, 170 hospitalized patients in the Urology ward in shahid beheshti hospital during the second half of 2018 were studied. Data were analyzed with SPSS 16. Results: The results showed that the average satisfaction rate of all services was 77.25%. However, the highest satisfaction with nursing services is 80.8 and the lowest satisfaction with public services is 72.6. There were significant relationships between demographic variables such as age, sex and level of education with total satisfaction. Conclusions: From the viewpoint of patients at Shahid Beheshti Hospital in Hamadan, the total services and facilities that report, are to be desirable.
Natural Hazards, 2019
Flooding is one of the most problematic natural events affecting urban areas. In this regard, dev... more Flooding is one of the most problematic natural events affecting urban areas. In this regard, developing flooding models plays a crucial role in reducing flood-induced losses and assists city managers to determine flooding-prone areas (FPAs). The aim of this study is to investigate on the prediction capability of fuzzy analytical hierarchy process (FAHP) and Mamdani fuzzy inference system (MFIS) methods as two completely and semi-knowledgebased models to identify FPAs in Tehran, Iran. Six flooding conditioning factors including density of channel, distance from channel, land use, elevation, slope, and water discharge were extracted from various geo-spatial datasets. A total of 62 flooding locations were identified in the study area based on the existing reports and field surveys. Of these, 44 (70%) floods were randomly selected as training data and the remaining 18 (30%) cases were used for the validation purposes. After the data preparation step, data were processed by means of two statistical (FAHP) and soft computing (MFIS) methods. Unlike most statistical and soft computing approaches which use flooding inventory data for both training and evaluation of models, only conditioning factor was involved in data processing and inventory data were used in the current study to assess models prediction accuracy. Also, the efficiency of two approaches was evaluated by pixel matching (PM) and area under curve to validate the prediction capability of models. The prediction rate for MFIS and FAHP was 89% and 84%, respectively. Moreover, according to the results obtained from PM, it was found out that about 90% of known flooding locations fell in high-risk areas, whereas it was 83% for FAHP, indicating that flooding susceptibility map of MFIS has higher performance.
Background: Nowadays, anesthetic drugs are widely used in anesthesia and surgical procedures and ... more Background: Nowadays, anesthetic drugs are widely used in anesthesia and surgical procedures and their effects on memory have been the focus of attention for a very long time. The effects of these common drugs include Dexmedetomidine (DEX) and Etomidate (ETO), on memory are controversial. In this study, the effects of these two drugs, co-administrated with heights stress, were evaluated on short-term and long-term spatial memory. 48 male mice were divided into 6 experimental groups consisting of Control, Control+heightstress (H.S), ETO, ETO+H.S, DEX+H.S. Drugs were administered Intra-peritoneal with doses of 0.3-0.4 mg/kg and 11 mg/kg for DEX and ETO respectively, and spatial memory was assessed using the Barnes Model. Results: DEX improved acquisition and retention of spatial reference memory, whereas ETO showed no such effects. In addition, DEX and ETO showed excitatory effects on short-term spatial memory, however DEX was more effective than ETO. Conclusion: the results suggested the neuoprotective, synaptic plasticity and memory improving effects of DEX on spatial reference and working memory. However, the precise neuronal and molecular mechanisms of these effects and their relation to the anti-stress system is still unknown and requires further research. Background: Anesthetic drugs are widely used in anesthesia and surgical procedures and their effects on memory have been the focus of attention for a very long time. The experience of height stress may result in stressrelated psychiatric disorders such as Post-traumatic stress disorder (PTSD). Which is a psychiatric disease that occurs after serious accidents, anxiety and fright(1). The symptoms of PTSD include increased sensitivity to stress, intrusive memory, hyperarousal, and avoidance (1, 2). During recent years, improvement of behavioral tasks which assess spatial learning and memory in rodents has us comprehend the role of the hippocampus in these cognitive functions (3). Allocentric navigation involves different parts such as the hippocampus, entorhinal cortex, and its surrounding structures while in the human body this system encodes allocentric, semantic, and episodic memory. This form of memory is assessed in laboratory animals in many ways, but one form of assessment is the Barnes maze (4). The primary aim of the pharmacotherapeutic agents for PTSD is to disrupt the memory consolidation and the associated fear conditioning response after exposure to an event (5, 6). The risk of PTSD occurrence in patients exposed to stressful medical conditions associated with perioperative awareness or Intensive Care Unit (ICU) treatment is moderately high (7-9). Patients treated in ICU for life-threatening medical events have multiple traumatic experiences and often develop severe
Journal of Chest Surgery, 2021
Background: Subclavian vein (SV) catheterization is a method for the delivery of fluids, drugs, a... more Background: Subclavian vein (SV) catheterization is a method for the delivery of fluids, drugs, and blood products, venous blood sampling, and central vein pressure monitoring in cardiac surgery. Catheter occlusion is a serious complication of SV catheterization during cardiac surgery, especially after sternal retractor expansion. Methods: In this observational study, 303 patients who had successful right infraclavicular SV catheterization from September 2019 to April 2020 were enrolled to determine the incidence of catheter occlusion. After catheterization, the lumens of all catheters were checked for the ability to infuse and withdraw blood from the catheter before and after sternal retractor expansion. The patients' characteristics, cannulation approach, on-pump or off-pump technique, occlusion of the catheter and its lumens, and any associated complications were recorded. The data were analyzed using IBM SPSS ver. 22.0 (IBM Corp., Armonk, NY, USA). Results: Of the 303 patients studied, 205 were male (67.7%) and 98 were female (32.3%). Catheter occlusion occurred in 11 patients with on-pump cardiopulmonary bypass (CPB) (227 patients) and 4 patients with off-pump CPB (76 patients) (p=0.863). The incidence of catheter occlusion was 4.95% (15 of 303 patients) with no cases of simultaneous 3-lumen occlusion in a catheter. The most commonly occluded lumen was the distal lumen (57.92%). Simultaneous 2-lumen occlusion occurred in 4 patients. Catheter occlusion was found in 3 of 13 malpositioned catheters (23.07%). Conclusion: The current study showed that malpositioning of the catheter tip was a risk factor for catheter occlusion and that the distal lumen of a triple-lumen catheter was the most commonly occluded lumen.
Brazilian Journal of Anesthesiology (English Edition), 2021
Phenylketonuria is a rare disorder that increases the levels of phenylalanine in the blood. As th... more Phenylketonuria is a rare disorder that increases the levels of phenylalanine in the blood. As there are scant articles about anesthesia management in phenylketonuria patients, this encouraged us to report a short-time anesthesia management of a child with phenylketonuria for bone fracture. The anesthesia was induced with intravenous ketamine and midazolam. During procedure, he received 100% oxygen via a face mask throughout spontaneous breathing. The operation was uneventful, and he was completely awakened in the recovery room. This report emphasizes that in some situations, the combination of midazolam with ketamine could be used safely for short time anesthesia in phenylketonuria patients.
Journal of Research in Urology, 2019
Background & Objective: Satisfaction is one of the health aspects of human. Without attention to ... more Background & Objective: Satisfaction is one of the health aspects of human. Without attention to people's satisfaction in the health services, the health system act contrary to its mission. The aim of this study is to evaluate the patient's satisfaction in the urology ward at Shahid Beheshti Hospital in Hamadan University of Medical Sciences in second half of 2018, for investigating the strengths and weaknesses with provide guidance and better quality treatments. Methods: In this cross-sectional study, 170 hospitalized patients in the Urology ward in shahid beheshti hospital during the second half of 2018 were studied. Data were analyzed with SPSS 16. Results: The results showed that the average satisfaction rate of all services was 77.25%. However, the highest satisfaction with nursing services is 80.8 and the lowest satisfaction with public services is 72.6. There were significant relationships between demographic variables such as age, sex and level of education with total satisfaction. Conclusions: From the viewpoint of patients at Shahid Beheshti Hospital in Hamadan, the total services and facilities that report, are to be desirable.
Natural Hazards, 2019
Flooding is one of the most problematic natural events affecting urban areas. In this regard, dev... more Flooding is one of the most problematic natural events affecting urban areas. In this regard, developing flooding models plays a crucial role in reducing flood-induced losses and assists city managers to determine flooding-prone areas (FPAs). The aim of this study is to investigate on the prediction capability of fuzzy analytical hierarchy process (FAHP) and Mamdani fuzzy inference system (MFIS) methods as two completely and semi-knowledgebased models to identify FPAs in Tehran, Iran. Six flooding conditioning factors including density of channel, distance from channel, land use, elevation, slope, and water discharge were extracted from various geo-spatial datasets. A total of 62 flooding locations were identified in the study area based on the existing reports and field surveys. Of these, 44 (70%) floods were randomly selected as training data and the remaining 18 (30%) cases were used for the validation purposes. After the data preparation step, data were processed by means of two statistical (FAHP) and soft computing (MFIS) methods. Unlike most statistical and soft computing approaches which use flooding inventory data for both training and evaluation of models, only conditioning factor was involved in data processing and inventory data were used in the current study to assess models prediction accuracy. Also, the efficiency of two approaches was evaluated by pixel matching (PM) and area under curve to validate the prediction capability of models. The prediction rate for MFIS and FAHP was 89% and 84%, respectively. Moreover, according to the results obtained from PM, it was found out that about 90% of known flooding locations fell in high-risk areas, whereas it was 83% for FAHP, indicating that flooding susceptibility map of MFIS has higher performance.