salih hamzah - Academia.edu (original) (raw)

Papers by salih hamzah

Research paper thumbnail of Association between Lipid Profiles and Renal Functions among Adults with Type 2 Diabetes

International journal of diabetes and metabolism, 2019

Introduction: Type 2 diabetes mellitus (T2DM) affects renal functions and lipid profiles of patie... more Introduction: Type 2 diabetes mellitus (T2DM) affects renal functions and lipid profiles of patients. Objectives: In this study, 100 patients (65 females, 35 males) with T2DM were evaluated to determine whether renal function characteristics and lipid profiles are associated with T2DM. Methods: Blood samples were collected from all patients with T2DM, and the levels of hemoglobin A 1c (HbA 1c), blood urea, serum creatinine, cholesterol, triglyceride (TGR), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very lowdensity lipoprotein (VLDL) were analyzed. Results: A direct correlation of blood sugar and HbA 1c was observed with blood urea, serum creatinine, serum cholesterol, serum TGR, HDL, LDL, and VLDL. The results revealed elevated TGR levels in patients administered medications for hyperglycemia. Furthermore, serum TGR levels were significantly correlated with blood sugar levels (p = 0.035). Blood urea levels were significantly correlated with glycated hemoglobin (p = 0.008). Blood urea, serum creatinine, and serum cholesterol levels were highly significantly correlated with HbA 1c (p = 0.008, 0.017, and 0.005, respectively), while HDL, LDL, and VLDL were not significantly correlated with HbA 1c. Conclusion: This study highlights the importance of serum TGR and serum creatinine measurement for guiding the treatment of T2DM.

Research paper thumbnail of Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels

Research paper thumbnail of Impact of Diabetes Mellitus Type 2 in the Activity of Glucose-6-Phosphate Dehydrogenase in Human Erythrocyte

Kurdistan journal of applied research, Jun 10, 2018

Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal... more Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal blood glucose poise. Glucose-6-phosphate dehydrogenase (G6PD) enzyme code (E.C.1.1.1.49) is an underlying enzyme in the phosphogluconate pathway. In this study, G6PD vitality in the mortal erythrocyte of male and female patients with type 2 diabetes mellitus was assessed utilizing a spectrophotometer at 340 nm. The activity of the enzyme increased with elevated glycated haemoglobin (HbA1C) levels. G6PD activity was found to be significantly associated with type 2 diabetes mellitus. The association between G6PD and diabetes mellitus was significant (P < 0.001). Moreover, G6PD was positively correlated with HbA1C levels (r = 0.572). The following mean ± standard deviation values were obtained:

Research paper thumbnail of Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels

Background and introduction Diabetes mellitus is a common systemic disease in nearly all countrie... more Background and introduction Diabetes mellitus is a common systemic disease in nearly all countries. Its prevalence has been increasing. Thus, early detection and control of this disorder are urgent tasks. The average blood glucose, salivary glucose, and glycosylated hemoglobin (HbA1c) levels must be estimated.

Research paper thumbnail of Impact of Diabetes Mellitus Type 2 in the Activity of Glucose-6-Phosphate Dehydrogenase in Human Erythrocyte

Kurdistan Journal of Applied Research, Jun 10, 2018

Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal... more Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal blood glucose poise. Glucose-6-phosphate dehydrogenase (G6PD) enzyme code (E.C.1.1.1.49) is an underlying enzyme in the phosphogluconate pathway. In this study, G6PD vitality in the mortal erythrocyte of male and female patients with type 2 diabetes mellitus was assessed utilizing a spectrophotometer at 340 nm. The activity of the enzyme increased with elevated glycated haemoglobin (HbA1C) levels. G6PD activity was found to be significantly associated with type 2 diabetes mellitus. The association between G6PD and diabetes mellitus was significant (P < 0.001). Moreover, G6PD was positively correlated with HbA1C levels (r = 0.572). The following mean ± standard deviation values were obtained:

Research paper thumbnail of Association between Lipid Profiles and Renal Functions among Adults with Type 2 Diabetes

International Journal of Diabetes and Metabolism

Introduction: Type 2 diabetes mellitus (T2DM) affects renal functions and lipid profiles of patie... more Introduction: Type 2 diabetes mellitus (T2DM) affects renal functions and lipid profiles of patients. Objectives: In this study, 100 patients (65 females, 35 males) with T2DM were evaluated to determine whether renal function characteristics and lipid profiles are associated with T2DM. Methods: Blood samples were collected from all patients with T2DM, and the levels of hemoglobin A 1c (HbA 1c), blood urea, serum creatinine, cholesterol, triglyceride (TGR), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very lowdensity lipoprotein (VLDL) were analyzed. Results: A direct correlation of blood sugar and HbA 1c was observed with blood urea, serum creatinine, serum cholesterol, serum TGR, HDL, LDL, and VLDL. The results revealed elevated TGR levels in patients administered medications for hyperglycemia. Furthermore, serum TGR levels were significantly correlated with blood sugar levels (p = 0.035). Blood urea levels were significantly correlated with glycated hemoglobin (p = 0.008). Blood urea, serum creatinine, and serum cholesterol levels were highly significantly correlated with HbA 1c (p = 0.008, 0.017, and 0.005, respectively), while HDL, LDL, and VLDL were not significantly correlated with HbA 1c. Conclusion: This study highlights the importance of serum TGR and serum creatinine measurement for guiding the treatment of T2DM.

Research paper thumbnail of Impact of Diabetes Mellitus Type 2 in the Activity of Glucose-6-Phosphate Dehydrogenase in Human Erythrocyte

Kurdistan Journal of Applied Research

Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal... more Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal blood glucose poise. Glucose-6-phosphate dehydrogenase (G6PD) enzyme code (E.C.1.1.1.49) is an underlying enzyme in the phosphogluconate pathway. In this study, G6PD vitality in the mortal erythrocyte of male and female patients with type 2 diabetes mellitus was assessed utilizing a spectrophotometer at 340 nm. The activity of the enzyme increased with elevated glycated hemoglobin (HbA1C) levels. G6PD activity was found to be significantly associated with type 2 diabetes mellitus. The association between G6PD and diabetes mellitus was significant (P < 0.001). Moreover, G6PD was positively correlated with HbA1C levels (r = 0.572). The following mean ± standard deviation values were obtained: G6PD activity (IU/g Hb), 3.1103 ± 0.79349; HbA1C (%), 8.6600 ± 1.63120; Hb (g/dL), 13.4933 ± 1.38836; platelet count (103/µl), 283.4667 ± 58.59312; WBC (103/µl), 7.4890 ± 1.49842; HCT (%), 45.0100...

Research paper thumbnail of GLUTATYON REDÜKTAZ ENZİMİNİN HİNDİ KARACİĞERİNDEN SAFLAŞTIRILMASI VE KARAKTERİZASYONU

ERZURUM 2010 Her hakkı saklıdır i ÖZET Yüksek Lisans Tezi GLUTATYON REDÜKTAZ ENZİMİNİN HİNDİ KARA... more ERZURUM 2010 Her hakkı saklıdır i ÖZET Yüksek Lisans Tezi GLUTATYON REDÜKTAZ ENZİMİNİN HİNDİ KARACİĞERİNDEN SAFLAŞTIRILMASI VE KARAKTERİZASYONU Pınar TAŞER Atatürk Üniversitesi Fen Bilimleri Enstitüsü Kimya Anabilim Dalı Danışman: Prof. Dr. Mehmet ÇİFTCİ Glutatyon redüktaz (Glutatyon: NADP+, oksidoredüktaz, E.C 1.8.1.7.; GR) enzimi hindi karaciğerinden saflaştırıldı. Saflaştırma işlemi homojenatın hazırlanması ve 2',5'-ADP Sepharose 4B afinite kromatografisi olmak üzere 2 basamakta gerçekleştirildi. 606,67 EÜ/mg protein spesifik aktivitesine sahip olan GR enzimi %10,75 verimle, 2476 kat saflaştırıldı. Enzim aktivitesi spektrofotometrik olarak 340 nm'de Beutler metoduna göre ölçüldü.

Research paper thumbnail of Association between Lipid Profiles and Renal Functions among Adults with Type 2 Diabetes

International journal of diabetes and metabolism, 2019

Introduction: Type 2 diabetes mellitus (T2DM) affects renal functions and lipid profiles of patie... more Introduction: Type 2 diabetes mellitus (T2DM) affects renal functions and lipid profiles of patients. Objectives: In this study, 100 patients (65 females, 35 males) with T2DM were evaluated to determine whether renal function characteristics and lipid profiles are associated with T2DM. Methods: Blood samples were collected from all patients with T2DM, and the levels of hemoglobin A 1c (HbA 1c), blood urea, serum creatinine, cholesterol, triglyceride (TGR), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very lowdensity lipoprotein (VLDL) were analyzed. Results: A direct correlation of blood sugar and HbA 1c was observed with blood urea, serum creatinine, serum cholesterol, serum TGR, HDL, LDL, and VLDL. The results revealed elevated TGR levels in patients administered medications for hyperglycemia. Furthermore, serum TGR levels were significantly correlated with blood sugar levels (p = 0.035). Blood urea levels were significantly correlated with glycated hemoglobin (p = 0.008). Blood urea, serum creatinine, and serum cholesterol levels were highly significantly correlated with HbA 1c (p = 0.008, 0.017, and 0.005, respectively), while HDL, LDL, and VLDL were not significantly correlated with HbA 1c. Conclusion: This study highlights the importance of serum TGR and serum creatinine measurement for guiding the treatment of T2DM.

Research paper thumbnail of Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels

Research paper thumbnail of Impact of Diabetes Mellitus Type 2 in the Activity of Glucose-6-Phosphate Dehydrogenase in Human Erythrocyte

Kurdistan journal of applied research, Jun 10, 2018

Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal... more Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal blood glucose poise. Glucose-6-phosphate dehydrogenase (G6PD) enzyme code (E.C.1.1.1.49) is an underlying enzyme in the phosphogluconate pathway. In this study, G6PD vitality in the mortal erythrocyte of male and female patients with type 2 diabetes mellitus was assessed utilizing a spectrophotometer at 340 nm. The activity of the enzyme increased with elevated glycated haemoglobin (HbA1C) levels. G6PD activity was found to be significantly associated with type 2 diabetes mellitus. The association between G6PD and diabetes mellitus was significant (P < 0.001). Moreover, G6PD was positively correlated with HbA1C levels (r = 0.572). The following mean ± standard deviation values were obtained:

Research paper thumbnail of Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels

Background and introduction Diabetes mellitus is a common systemic disease in nearly all countrie... more Background and introduction Diabetes mellitus is a common systemic disease in nearly all countries. Its prevalence has been increasing. Thus, early detection and control of this disorder are urgent tasks. The average blood glucose, salivary glucose, and glycosylated hemoglobin (HbA1c) levels must be estimated.

Research paper thumbnail of Impact of Diabetes Mellitus Type 2 in the Activity of Glucose-6-Phosphate Dehydrogenase in Human Erythrocyte

Kurdistan Journal of Applied Research, Jun 10, 2018

Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal... more Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal blood glucose poise. Glucose-6-phosphate dehydrogenase (G6PD) enzyme code (E.C.1.1.1.49) is an underlying enzyme in the phosphogluconate pathway. In this study, G6PD vitality in the mortal erythrocyte of male and female patients with type 2 diabetes mellitus was assessed utilizing a spectrophotometer at 340 nm. The activity of the enzyme increased with elevated glycated haemoglobin (HbA1C) levels. G6PD activity was found to be significantly associated with type 2 diabetes mellitus. The association between G6PD and diabetes mellitus was significant (P < 0.001). Moreover, G6PD was positively correlated with HbA1C levels (r = 0.572). The following mean ± standard deviation values were obtained:

Research paper thumbnail of Association between Lipid Profiles and Renal Functions among Adults with Type 2 Diabetes

International Journal of Diabetes and Metabolism

Introduction: Type 2 diabetes mellitus (T2DM) affects renal functions and lipid profiles of patie... more Introduction: Type 2 diabetes mellitus (T2DM) affects renal functions and lipid profiles of patients. Objectives: In this study, 100 patients (65 females, 35 males) with T2DM were evaluated to determine whether renal function characteristics and lipid profiles are associated with T2DM. Methods: Blood samples were collected from all patients with T2DM, and the levels of hemoglobin A 1c (HbA 1c), blood urea, serum creatinine, cholesterol, triglyceride (TGR), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very lowdensity lipoprotein (VLDL) were analyzed. Results: A direct correlation of blood sugar and HbA 1c was observed with blood urea, serum creatinine, serum cholesterol, serum TGR, HDL, LDL, and VLDL. The results revealed elevated TGR levels in patients administered medications for hyperglycemia. Furthermore, serum TGR levels were significantly correlated with blood sugar levels (p = 0.035). Blood urea levels were significantly correlated with glycated hemoglobin (p = 0.008). Blood urea, serum creatinine, and serum cholesterol levels were highly significantly correlated with HbA 1c (p = 0.008, 0.017, and 0.005, respectively), while HDL, LDL, and VLDL were not significantly correlated with HbA 1c. Conclusion: This study highlights the importance of serum TGR and serum creatinine measurement for guiding the treatment of T2DM.

Research paper thumbnail of Impact of Diabetes Mellitus Type 2 in the Activity of Glucose-6-Phosphate Dehydrogenase in Human Erythrocyte

Kurdistan Journal of Applied Research

Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal... more Diabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal blood glucose poise. Glucose-6-phosphate dehydrogenase (G6PD) enzyme code (E.C.1.1.1.49) is an underlying enzyme in the phosphogluconate pathway. In this study, G6PD vitality in the mortal erythrocyte of male and female patients with type 2 diabetes mellitus was assessed utilizing a spectrophotometer at 340 nm. The activity of the enzyme increased with elevated glycated hemoglobin (HbA1C) levels. G6PD activity was found to be significantly associated with type 2 diabetes mellitus. The association between G6PD and diabetes mellitus was significant (P < 0.001). Moreover, G6PD was positively correlated with HbA1C levels (r = 0.572). The following mean ± standard deviation values were obtained: G6PD activity (IU/g Hb), 3.1103 ± 0.79349; HbA1C (%), 8.6600 ± 1.63120; Hb (g/dL), 13.4933 ± 1.38836; platelet count (103/µl), 283.4667 ± 58.59312; WBC (103/µl), 7.4890 ± 1.49842; HCT (%), 45.0100...

Research paper thumbnail of GLUTATYON REDÜKTAZ ENZİMİNİN HİNDİ KARACİĞERİNDEN SAFLAŞTIRILMASI VE KARAKTERİZASYONU

ERZURUM 2010 Her hakkı saklıdır i ÖZET Yüksek Lisans Tezi GLUTATYON REDÜKTAZ ENZİMİNİN HİNDİ KARA... more ERZURUM 2010 Her hakkı saklıdır i ÖZET Yüksek Lisans Tezi GLUTATYON REDÜKTAZ ENZİMİNİN HİNDİ KARACİĞERİNDEN SAFLAŞTIRILMASI VE KARAKTERİZASYONU Pınar TAŞER Atatürk Üniversitesi Fen Bilimleri Enstitüsü Kimya Anabilim Dalı Danışman: Prof. Dr. Mehmet ÇİFTCİ Glutatyon redüktaz (Glutatyon: NADP+, oksidoredüktaz, E.C 1.8.1.7.; GR) enzimi hindi karaciğerinden saflaştırıldı. Saflaştırma işlemi homojenatın hazırlanması ve 2',5'-ADP Sepharose 4B afinite kromatografisi olmak üzere 2 basamakta gerçekleştirildi. 606,67 EÜ/mg protein spesifik aktivitesine sahip olan GR enzimi %10,75 verimle, 2476 kat saflaştırıldı. Enzim aktivitesi spektrofotometrik olarak 340 nm'de Beutler metoduna göre ölçüldü.