samanta nunes - Academia.edu (original) (raw)
Papers by samanta nunes
Avaliação físico-química e biológica da eficácia de uma água mineral lipossomada na pele Physico-... more Avaliação físico-química e biológica da eficácia de uma água mineral lipossomada na pele Physico-chemical and biological effectiveness evaluation of a liposome-enhanced mineral water on the skin
Anais Brasileiros de Dermatologia
Background: Acne in women is often associated with anxiety and depression, and may persist from a... more Background: Acne in women is often associated with anxiety and depression, and may persist from adolescence as well as manifest for the first time in adulthood. Genetic and hormonal factors contribute to its etiopathogenesis, and maintenance treatment is required, usually for years, due to its clinical evolution. oBjective: To develop a guide for the clinical practice of adult female acne. Methods: A team of five experts with extensive experience in acne conducted a literature review of the main scientific evidence and met to discuss the best practices and personal experiences to develop a guide containing recommendations for the clinical practice of adult female acne. results: The group of specialists reached consensus on the main guidelines for clinical practice, providing detailed recommendations on clinical picture, etiopathogenesis, laboratory investigation and treatment of adult female acne. conclusion: Different from teenage acne, adult female acne presents some characteristics and multiple etiopathogenic factors that make its management more complex. This guide provides recommendations for best clinical practices and therapeutic decisions. However, the authors consider that additional studies are needed in order to provide more evidence for adult female acne to be better understood.
Diabetology & Metabolic Syndrome, 2016
Skin disorders, usually neglected and frequently underdiagnosed among diabetic patients, are comm... more Skin disorders, usually neglected and frequently underdiagnosed among diabetic patients, are common complications and encounter a broad spectrum of disorders in both type 1 and type 2 diabetes mellitus (DM)-e.g. cutaneous infection, dry skin, pruritus. Skin disorders are highly associated with increased risk of important outcomes, such as skin lesions, ulcerations and diabetic foot, which can lead to major complications and revolve around multifactorial factors besides hyperglycemia and advanced glycation end products. Although diabetic's skin disorders are consistent in the literature, there is limited data regarding early-stage skin disorders in DM patients. Disease control, early-stage treatment (e.g. skin hydration, orthotic devices) and awareness can reduce morbidity of DM patients. Thus, better understanding of the burden of skin disorders in DM patients may raise awareness on prevention and management. Therefore, the aim of this study is to perform a literature review to evaluate the main clinical characteristics and complications of skin disorders in diabetic's patients. Additionally, physiopathology early-stage skin disorders and dermocosmetic management were also reviewed.
Surgical Cosmetic Dermatology, 2012
Avaliação físico-química e biológica da eficácia de uma água mineral lipossomada na pele Physico-... more Avaliação físico-química e biológica da eficácia de uma água mineral lipossomada na pele Physico-chemical and biological effectiveness evaluation of a liposome-enhanced mineral water on the skin
Surgical Cosmetic Dermatology, 2012
Revisão histórica das águas termais A historical review of mineral water RESU MO A indústria fran... more Revisão histórica das águas termais A historical review of mineral water RESU MO A indústria francesa de cosméticos tem comercializado águas minerais termais com alguns efeitos biológicos. Tem sido demonstrado que elementos oligominerais têm propriedades hidratantes, antioxidantes e anti-inflamatórias. Este trabalho de revisão aborda estudos clínicos in vitro e in vivo com águas minerais termais disponíveis comercialmente, determinando seus efeitos na pele, assim como suas principais indicações. Também foram feitas a revisão histórica dos usos de águas minerais termais na dermatologia com foco na identificação de suas propriedades físicas e químicas, bem como a comparação entre a composição qualitativa dos oligoelementos dessas águas.
Diabetology & Metabolic Syndrome, 2015
Anais brasileiros de dermatologia
The use of topical antifungal agents in the treatment of onychomycosis is of great value in clini... more The use of topical antifungal agents in the treatment of onychomycosis is of great value in clinical practice as there are different limitations regarding the use of systemic treatment. To evaluate the efficacy and safety of a nail lacquer formulation containing ciclopirox 8% in two different posologies: the traditional regimen (3/2/1) and a regimen of weekly use. A blind, randomized, comparative trial which included 41 patients divided into 02 groups, with Group I using the nail lacquer once weekly and Group II using the traditional regimen (3/2/1). Both groups applied the medication for 06 months. The species most frequently found in groups I and II were Trichophyton rubrum (55% and 61.9%) and Trichophyton mentagrophytes (30% and 19%). There was a tendency to a higher level of treatment resistance by T. mentagrophytes infection in both groups, without any predilection for sex, age, proportion of the nail affected at the beginning of the study, duration of the clinical disease and ...
Introduction: The French cosmetics industry sells spring mineral waters that are advertised as ha... more Introduction: The French cosmetics industry sells spring mineral waters that are advertised as having biological benefits. Objective: This study analyzes, in vitro and in vivo, a Brazilian mineral water's oligominerals composition, as well as its physical and chemical characteristics and biological effects. Methods: Tests to evaluate physical chemical properties, cytotoxicity (viable cells) and irritability (het-cam test) were conducted. In vitro studies were performed to evaluate its capacity to induce the genic expression and immunohistochemical detection of filaggrin and aquaporin 3, nf-kb activity and fibroblast proliferation compared to Milli Q water. Results: This water was found to be non-cytotoxic and non-irritating. In addition, it presented a high content of strontium (0.61 mg/ml). The expression of filaggrin and its immunohistochemical tests were relevant. The aquaporin 3 increased 1.8 times and nf-kb decreased its activity by 47%. It was also capable of stimulating f...
Surgical & Cosmetic Dermatology
Avaliação físico-química e biológica da eficácia de uma água mineral lipossomada na pele Physico-... more Avaliação físico-química e biológica da eficácia de uma água mineral lipossomada na pele Physico-chemical and biological effectiveness evaluation of a liposome-enhanced mineral water on the skin
Anais Brasileiros de Dermatologia
Background: Acne in women is often associated with anxiety and depression, and may persist from a... more Background: Acne in women is often associated with anxiety and depression, and may persist from adolescence as well as manifest for the first time in adulthood. Genetic and hormonal factors contribute to its etiopathogenesis, and maintenance treatment is required, usually for years, due to its clinical evolution. oBjective: To develop a guide for the clinical practice of adult female acne. Methods: A team of five experts with extensive experience in acne conducted a literature review of the main scientific evidence and met to discuss the best practices and personal experiences to develop a guide containing recommendations for the clinical practice of adult female acne. results: The group of specialists reached consensus on the main guidelines for clinical practice, providing detailed recommendations on clinical picture, etiopathogenesis, laboratory investigation and treatment of adult female acne. conclusion: Different from teenage acne, adult female acne presents some characteristics and multiple etiopathogenic factors that make its management more complex. This guide provides recommendations for best clinical practices and therapeutic decisions. However, the authors consider that additional studies are needed in order to provide more evidence for adult female acne to be better understood.
Diabetology & Metabolic Syndrome, 2016
Skin disorders, usually neglected and frequently underdiagnosed among diabetic patients, are comm... more Skin disorders, usually neglected and frequently underdiagnosed among diabetic patients, are common complications and encounter a broad spectrum of disorders in both type 1 and type 2 diabetes mellitus (DM)-e.g. cutaneous infection, dry skin, pruritus. Skin disorders are highly associated with increased risk of important outcomes, such as skin lesions, ulcerations and diabetic foot, which can lead to major complications and revolve around multifactorial factors besides hyperglycemia and advanced glycation end products. Although diabetic's skin disorders are consistent in the literature, there is limited data regarding early-stage skin disorders in DM patients. Disease control, early-stage treatment (e.g. skin hydration, orthotic devices) and awareness can reduce morbidity of DM patients. Thus, better understanding of the burden of skin disorders in DM patients may raise awareness on prevention and management. Therefore, the aim of this study is to perform a literature review to evaluate the main clinical characteristics and complications of skin disorders in diabetic's patients. Additionally, physiopathology early-stage skin disorders and dermocosmetic management were also reviewed.
Surgical Cosmetic Dermatology, 2012
Avaliação físico-química e biológica da eficácia de uma água mineral lipossomada na pele Physico-... more Avaliação físico-química e biológica da eficácia de uma água mineral lipossomada na pele Physico-chemical and biological effectiveness evaluation of a liposome-enhanced mineral water on the skin
Surgical Cosmetic Dermatology, 2012
Revisão histórica das águas termais A historical review of mineral water RESU MO A indústria fran... more Revisão histórica das águas termais A historical review of mineral water RESU MO A indústria francesa de cosméticos tem comercializado águas minerais termais com alguns efeitos biológicos. Tem sido demonstrado que elementos oligominerais têm propriedades hidratantes, antioxidantes e anti-inflamatórias. Este trabalho de revisão aborda estudos clínicos in vitro e in vivo com águas minerais termais disponíveis comercialmente, determinando seus efeitos na pele, assim como suas principais indicações. Também foram feitas a revisão histórica dos usos de águas minerais termais na dermatologia com foco na identificação de suas propriedades físicas e químicas, bem como a comparação entre a composição qualitativa dos oligoelementos dessas águas.
Diabetology & Metabolic Syndrome, 2015
Anais brasileiros de dermatologia
The use of topical antifungal agents in the treatment of onychomycosis is of great value in clini... more The use of topical antifungal agents in the treatment of onychomycosis is of great value in clinical practice as there are different limitations regarding the use of systemic treatment. To evaluate the efficacy and safety of a nail lacquer formulation containing ciclopirox 8% in two different posologies: the traditional regimen (3/2/1) and a regimen of weekly use. A blind, randomized, comparative trial which included 41 patients divided into 02 groups, with Group I using the nail lacquer once weekly and Group II using the traditional regimen (3/2/1). Both groups applied the medication for 06 months. The species most frequently found in groups I and II were Trichophyton rubrum (55% and 61.9%) and Trichophyton mentagrophytes (30% and 19%). There was a tendency to a higher level of treatment resistance by T. mentagrophytes infection in both groups, without any predilection for sex, age, proportion of the nail affected at the beginning of the study, duration of the clinical disease and ...
Introduction: The French cosmetics industry sells spring mineral waters that are advertised as ha... more Introduction: The French cosmetics industry sells spring mineral waters that are advertised as having biological benefits. Objective: This study analyzes, in vitro and in vivo, a Brazilian mineral water's oligominerals composition, as well as its physical and chemical characteristics and biological effects. Methods: Tests to evaluate physical chemical properties, cytotoxicity (viable cells) and irritability (het-cam test) were conducted. In vitro studies were performed to evaluate its capacity to induce the genic expression and immunohistochemical detection of filaggrin and aquaporin 3, nf-kb activity and fibroblast proliferation compared to Milli Q water. Results: This water was found to be non-cytotoxic and non-irritating. In addition, it presented a high content of strontium (0.61 mg/ml). The expression of filaggrin and its immunohistochemical tests were relevant. The aquaporin 3 increased 1.8 times and nf-kb decreased its activity by 47%. It was also capable of stimulating f...
Surgical & Cosmetic Dermatology