samrin shaikh - Academia.edu (original) (raw)

Papers by samrin shaikh

Research paper thumbnail of Direct Conversion of N-acetyl-d-glucosamine to N-containing Heterocyclic Compounds 3-Acetamidofuran and 3-Acetamido-5-acetyl Furan

Waste and Biomass Valorization

Research paper thumbnail of Cooperative Acid‐Base Sites of Solid Ba‐Zr Mixed Oxide Catalyst for Efficient Isomerization of Glucose to Fructose in Aqueous Medium

Research paper thumbnail of Direct Conversion of N-Acetyl-D-glucosamine to N- containing heterocyclic compounds 3-acetamidofuran and 3-acetamido-5-acetly furan

Research Square (Research Square), Nov 28, 2022

Effectual waste utilization from plant as well as marine biomass has gained tremendous importance... more Effectual waste utilization from plant as well as marine biomass has gained tremendous importance with reference to sustainability. The valorization of marine biomass produces value added compounds containing not only C, H, O but also renewable N atom in the skeleton which widens the scope for its exploration which may prove to be economically bene cial to the society. Heterogeneous catalytic transformation of marine biomass i.e. N-acetyl glucosamine (NAG) to N-substituted aromatic heterocyclic is reported for the very rst time. Cost effective and stable metal oxide catalysts were deployed for the transformation. Catalyst screening study showed that La 2 O 3 was found to be an excellent catalyst for N-acetyl glucosamine (NAG) dehydration which mainly produced 3-acetamidofuran (3AF). The physicochemical properties of the metal oxide catalyst were investigated by various techniques such as XRD, FTIR, MeOH-FTIR, TPD, SEM, N 2 sorption studies and HR-TEM analysis for structure activity relationship. The effect of various reaction parameters such as catalyst concentration, reaction temperature, reaction time and solvent effect on dehydration of N-acetyl glucosamine has been studied in detail for higher yields. The results revealed that the presence of weak basic sites which are Brønsted in nature and nano pores present on the surface were responsible for improved dehydration of the chitin biomass to selectively yield 3-acetamidofuran (3AF). La 2 O 3 catalyst showed optimum 50% 3AF yield from N-Acetyl glucosamine at 180 ºC in 3h. E cacious exploitation of marine biomass to value added chemicals using heterogeneous catalyst through simple route and easy separation of N-substituted heterocyclic aromatics is the most innovative aspect of the current study. Thus, utilization of heterogeneous catalyst and renewable biomass as a raw material indicates a transition towards more sustainable and greener approach. Statement Of Novelty As marine biomass is abundantly available on valorization widens its scope for production of value added products and platform chemicals. As far as sustainability and green synthesis is concerned we report for the rst time dehydration of NAG to renewable N-containing furan derivatives by heterogeneous catalyst without use of any additives, ionic liquids or boron compounds. The catalyst showed high stability, easy separation and excellent recyclability upto 5 cycles. The cooperative effect of Brønsted basicity and nanopores on the catalyst play vital role in (100 %) NAG conversion to yield 50 % 3AF and 20 % 3A5AF. 3AF and 3A5AF may nd application as precursors for the synthesis of naturally occurring antibiotic and antitumor drug proximycin A, B and C, amino sugars, pyridine derivatives etc.

Research paper thumbnail of Cooperative Acid‐Base Sites of Solid Ba‐Zr Mixed Oxide Catalyst for Efficient Isomerization of Glucose to Fructose in Aqueous Medium

Research paper thumbnail of Convenient semihydrogenation of azoarenes to hydrazoarenes using H2

Organic & Biomolecular Chemistry

Convenient and highly selective hydrogenation reaction of azoarenes using molecular hydrogen to a... more Convenient and highly selective hydrogenation reaction of azoarenes using molecular hydrogen to access diverse hydrazoarenes is reported.

Research paper thumbnail of Direct Conversion of N-acetyl-d-glucosamine to N-containing Heterocyclic Compounds 3-Acetamidofuran and 3-Acetamido-5-acetyl Furan

Waste and Biomass Valorization

Research paper thumbnail of Cooperative Acid‐Base Sites of Solid Ba‐Zr Mixed Oxide Catalyst for Efficient Isomerization of Glucose to Fructose in Aqueous Medium

Research paper thumbnail of Direct Conversion of N-Acetyl-D-glucosamine to N- containing heterocyclic compounds 3-acetamidofuran and 3-acetamido-5-acetly furan

Research Square (Research Square), Nov 28, 2022

Effectual waste utilization from plant as well as marine biomass has gained tremendous importance... more Effectual waste utilization from plant as well as marine biomass has gained tremendous importance with reference to sustainability. The valorization of marine biomass produces value added compounds containing not only C, H, O but also renewable N atom in the skeleton which widens the scope for its exploration which may prove to be economically bene cial to the society. Heterogeneous catalytic transformation of marine biomass i.e. N-acetyl glucosamine (NAG) to N-substituted aromatic heterocyclic is reported for the very rst time. Cost effective and stable metal oxide catalysts were deployed for the transformation. Catalyst screening study showed that La 2 O 3 was found to be an excellent catalyst for N-acetyl glucosamine (NAG) dehydration which mainly produced 3-acetamidofuran (3AF). The physicochemical properties of the metal oxide catalyst were investigated by various techniques such as XRD, FTIR, MeOH-FTIR, TPD, SEM, N 2 sorption studies and HR-TEM analysis for structure activity relationship. The effect of various reaction parameters such as catalyst concentration, reaction temperature, reaction time and solvent effect on dehydration of N-acetyl glucosamine has been studied in detail for higher yields. The results revealed that the presence of weak basic sites which are Brønsted in nature and nano pores present on the surface were responsible for improved dehydration of the chitin biomass to selectively yield 3-acetamidofuran (3AF). La 2 O 3 catalyst showed optimum 50% 3AF yield from N-Acetyl glucosamine at 180 ºC in 3h. E cacious exploitation of marine biomass to value added chemicals using heterogeneous catalyst through simple route and easy separation of N-substituted heterocyclic aromatics is the most innovative aspect of the current study. Thus, utilization of heterogeneous catalyst and renewable biomass as a raw material indicates a transition towards more sustainable and greener approach. Statement Of Novelty As marine biomass is abundantly available on valorization widens its scope for production of value added products and platform chemicals. As far as sustainability and green synthesis is concerned we report for the rst time dehydration of NAG to renewable N-containing furan derivatives by heterogeneous catalyst without use of any additives, ionic liquids or boron compounds. The catalyst showed high stability, easy separation and excellent recyclability upto 5 cycles. The cooperative effect of Brønsted basicity and nanopores on the catalyst play vital role in (100 %) NAG conversion to yield 50 % 3AF and 20 % 3A5AF. 3AF and 3A5AF may nd application as precursors for the synthesis of naturally occurring antibiotic and antitumor drug proximycin A, B and C, amino sugars, pyridine derivatives etc.

Research paper thumbnail of Cooperative Acid‐Base Sites of Solid Ba‐Zr Mixed Oxide Catalyst for Efficient Isomerization of Glucose to Fructose in Aqueous Medium

Research paper thumbnail of Convenient semihydrogenation of azoarenes to hydrazoarenes using H2

Organic & Biomolecular Chemistry

Convenient and highly selective hydrogenation reaction of azoarenes using molecular hydrogen to a... more Convenient and highly selective hydrogenation reaction of azoarenes using molecular hydrogen to access diverse hydrazoarenes is reported.