samuel coimbra - Academia.edu (original) (raw)
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Papers by samuel coimbra
Current Organic Chemistry, 2006
The preparation of steroids containing oxygenated functions in suitable positions of the steroid ... more The preparation of steroids containing oxygenated functions in suitable positions of the steroid nucleus is of great importance and can be achieved by means of several oxidative processes. In this paper allylic oxidation, -selective epoxidation, alcohol oxidation and remote functionalization reactions in steroid substrates are reviewed. Focus has been given to catalytic processes because of their major importance from the viewpoint of synthetic organic chemistry.
Tetrahedron, 2007
Various allylic and benzylic substrates were selectively oxidized to the corresponding enones in ... more Various allylic and benzylic substrates were selectively oxidized to the corresponding enones in good yields using sodium chlorite, either in combination with tert-butyl hydroperoxide in stoichiometric conditions, or associated with N-hydroxyphthalimide as catalyst. These oxidation reactions were effectively and economically performed under mild, transition-metal free conditions and therefore the dual challenge of cost effectiveness and benign nature of the processes was met with.
Current Organic Chemistry, 2006
The preparation of steroids containing oxygenated functions in suitable positions of the steroid ... more The preparation of steroids containing oxygenated functions in suitable positions of the steroid nucleus is of great importance and can be achieved by means of several oxidative processes. In this paper allylic oxidation, -selective epoxidation, alcohol oxidation and remote functionalization reactions in steroid substrates are reviewed. Focus has been given to catalytic processes because of their major importance from the viewpoint of synthetic organic chemistry.
Tetrahedron, 2007
Various allylic and benzylic substrates were selectively oxidized to the corresponding enones in ... more Various allylic and benzylic substrates were selectively oxidized to the corresponding enones in good yields using sodium chlorite, either in combination with tert-butyl hydroperoxide in stoichiometric conditions, or associated with N-hydroxyphthalimide as catalyst. These oxidation reactions were effectively and economically performed under mild, transition-metal free conditions and therefore the dual challenge of cost effectiveness and benign nature of the processes was met with.