shahana Arshi - Academia.edu (original) (raw)

Papers by shahana Arshi

The Professional Medical Journal

Objective: To determine frequency and patterns of coronary artery disease in patients with glomer... more Objective: To determine frequency and patterns of coronary artery disease in patients with glomerular hyper filtration (GHF), presented with acute coronary syndrome (ACS). Study Design: Cross Sectional, Retrospective study. Setting: Tertiary Healthcare Centre, Karachi. Period: July 2018 to July 2021. Material & Methods: Twelve hundred and sixty seven patients undergone Coronary angiography (CAG) for ACS having estimated glomerular filtration rate (eGFR) calculated through Cockcroft-Gault equation >90ml/min were selected. They were divided into two groups on the basis of eGFR, group A with normal eGFR (90-120ml/min) and B with eGFR i-e >120ml/min with glomerular hyper filtration (GHF). Variables like age, gender, BMI, Diabetes mellitus (DM), Hypertension, Smoking, history of previous cardiovascular diseases (CVD) and family history of CVD and obesity were studied. Findings of CAG results from Cath lab were also noted down. All the relevant data was analyzed through SPSS 16. Res...

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2016

OBJECTIVE To determine the frequency of IgAnephropathy presenting at a tertiary care hospital. ST... more OBJECTIVE To determine the frequency of IgAnephropathy presenting at a tertiary care hospital. STUDY DESIGN Across sectional, observational study. PLACE AND DURATION OF STUDY Pakistan Institute of Medical Sciences, Islamabad and Shifa International Hospital, Islamabad, Pakistan, from November 2008 to November 2014. METHODOLOGY This was a retrospective analysis of renal biopsies for the diagnosis of nephropathy during the study period. Biopsies were stained with fluorescence isothyocyanate (FITC) labelled antibodies against IgG, IgA, IgM, C3, C4 and C1q for fluorescent microscopy. For histopathological examination, the specimens were stained with hematoxylin and eosin, Periodic acid Schiff and methanamine silver stains for light microscopy. RESULTS Out of total 1,658 renal biopsy cases, 142 (8.6%) were diagnosed as IgA nephropathy on light and immunofluorescence microscopy. Majority of IgAnephropathy patients were young (mean age = 33.2) and presented with proteinuria. The frequency ...

Objective: The objective of this study was to see echocardiographic findings of cardiac dysfuncti... more Objective: The objective of this study was to see echocardiographic findings of cardiac dysfunction in patients of chronic kidney disease (CKD) on hemodialysis. Study Design: Comparative cross sectional study. Place and Duration of Study: Department of nephrology, Pakistan Institute of Medical Sciences. Islamabad from September 2014 to February 2015. Patients and Methods: One hundred patients of either gender were included in this study. Fifty patients of chronic kidney disease stage V on hemodialysis were taken for echocardiography and fifty were normal. Echocardiography was done for cardiac dysfunction. Systolic function was measured by ejection fraction (EF) and fractional shortening (FS). Diastolic function was measured by E/A ratio. Results: Out of 100 patients included in the study, 50 patients were on hemodialysis and 50 were control. Left ventricular end systolic and end diastolic volumes were higher in patients on hemodialysis than controls as well as left atrial enlargemen...

The Professional Medical Journal, 2013

Objective: To see the frequency of diabetes mellitus and impaired fasting glucose levels in hyper... more Objective: To see the frequency of diabetes mellitus and impaired fasting glucose levels in hypertensive patients. Design:Descriptive study. Place of Study: OPD / Filter clinic. Pakistan Institute of Medical Sciences. Islamabad. Patients and Methods: Thisstudy was carried out on 116 hypertensive patients during the period from August to September '2008. Out of 116 patients, 64 werefemales and 52 were males with age group between 20 to 70 years. Secondary causes are ruled out on the basis of history and physicalexamination. Blood samples were sent to PIMS laboratory for fasting glucose. Data and results were analyzed in SPSS. Results:According to this study, out of 116 patients, there were18 patients who had diabetes mellitus while 33 had hypertension with impairedfasting glucose tolerance which is statistically significant. The females as compared to males were increased in number who had bothdiabetes mellitus and impaired fasting glucose. According to age diabetes mellitus incr...

The Professional Medical Journal, 2011

ABSTRACT…Objective: To evaluate association of hypertension with central obesity in low to middle... more ABSTRACT…Objective: To evaluate association of hypertension with central obesity in low to middle socioeconomic population. Study design: Descriptive study. Setting: OPD, Filter Clinic. Pakistan Institute of Medical Sciences. Islamabad. Period: June to September 2008. Methods: This study was carried out on 85 patients with history of hypertension. Out of total patients, 27 were males and 58 were females. The ages of the all patients were between 20 to 70 years. Parameters recorded included history, blood pressure, weight, height, waist circumference and hip circumference. The secondary causes were ruled out on the basis of history and physical examination. Data and results were analyzed in SPSS. Results: Out of 85 patients, 74 including 21 males and 53 females had increased Waist Hip Ratio (WHR), 66 including 14 males and 61 females had increased Waist Circumference (WC), while the Body Mass Index (BMI) of 33 including 6 males & 27 females were found obese. It also showed that the f...

from 17th July to 17th October 2010. Patients and Methods: One hundred consecutive hypertensive p... more from 17th July to 17th October 2010. Patients and Methods: One hundred consecutive hypertensive patients with stroke were analysed for this study. Results: Total of 100 cases, 52 cases were of ischemic stroke. Out of this, 50% had left middle cerebral artery, 42.30% right middle cerebral artery, 3.85% anterior cerebral artery and 3.85% posterior cerebral artery involved. 48 cases had haemorrhagic stroke. The cerebellum was involved in 2.08%, 2.08% had left anterior lobe involved. Pons and right parietal lobe was involved in 2.08% respectively. SAH in 12.50%, left basal ganglia in 29.17% and right basal ganglia was involved in 43.76%. Conclusions: The reported results suggest that in hypertensive patients the frequency of ischemic stroke is greater than hemorrhagic stroke. 7 8

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