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Papers by shawana haque

Bangladesh Medical Journal

Psoriasis is a common chronic inflammatory disease of skin and multiple organs of body. The exact... more Psoriasis is a common chronic inflammatory disease of skin and multiple organs of body. The exact etiology of psoriasis is not yet certain. It is assumed that trace elements may have some role in pathogenesis of psoriasis. They can act as co-enzymes for metabolism and can act as antioxidants against free radicals. Therefore they can participate in epidermal proliferation and inflammatory process of psoriasis. This study aimed to evaluate the relation between psoriasis and trace elements namely zinc and copper. This study was conducted on 40 diagnosed cases of psoriasis and 40 non psoriatic individuals in the department of Dermatology and Venereology in Bangabandhu Sheikh Mujib Medical University, Dhaka. Biochemical analyses of serum copper and zinc were analyzed and compared statistically with cases and healthy controls. Serum zinc level was significantly lower and serum copper level was significantly higher in patient with psoriasis compared to control (p= < 0.001). Individuals ...

Community Based Medical Journal

A cross-sectional study was conducted in the Department of Biochemistry and Molecular Biology of ... more A cross-sectional study was conducted in the Department of Biochemistry and Molecular Biology of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh, between July 2016 and June 2017, to evaluate serum zinc level and its relationship with glycemic control in type 1 diabetic children. A total of 160 participants (all aged between 1 and 18 years) were selected from the outpatient department (OPD) of BIRDEM General Hospital-2, Dhaka – 80 type 1 diabetic children as cases and 80 apparently healthy children as controls. We measured anthropometric parameters all study subjects. Serum zinc level was assessed using colorimetric method. Fasting plasma glucose level was estimated using enzymatic glucose-oxidase method. Glycemic control was evaluated through estimation of HbA1c using a high-performance liquid chromatographic method. The mean serum zinc levels were significantly lower in patient with type 1 DM compared to...

Objective This study was designed to establish polymerase chain reaction (PCR) as a more effectiv... more Objective This study was designed to establish polymerase chain reaction (PCR) as a more effective tool for diagnose cutaneous tuberculosis (TB). Methods This cross-sectional study was conducted in the department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, over a duration of one year. Thirty clinically diagnosed patients of cutaneous tuberculosis were selected for this study. The selected skin lesion was biopsied and it was divided in two portions, one for histopathological examination and another for bacteriological Ziehl-Neelsen (Z-N) staining, culture and molecular PCR analysis. Results In our study mean age was found 34.5±16.6 years, male to female ratio was 1.3:1. Tuberculosis verrucosa cutis (43%) was the commonest type of skin TB than lupus vulgaris (30%), erythema induratum of Bazin (13.3%) and others cutaneous types (13.3%). Concomitant pulmonary tuberculosis was detected in 10% of examined patients. In histopatholog...

Bony changes in lepromatous leprosy are one of the causes of deformity and disability. Fasting ca... more Bony changes in lepromatous leprosy are one of the causes of deformity and disability. Fasting calcium and creatinine ratio in urine is used as a bone resorption marker in a number of diseases such as hyperthyroidism, osteoporosis, multiple myeloma, paget’s disease and sarcodosis. In lepromatous leprosy assessment of bone resorption might be done with that marker. To assess the role of fasting urinary calcium and creatinine ratio as a marker of bone resorption in patients with lepromatous leprosy. A case control study was conducted on 28 patients diagnosed as lepromatous leprosy and 28 age-matched healthy control. The participants who fulfilled all inclusion and exclusion criteria were studied by measuring fasting urinary calcium and creatinine level as well as observing X-rays of both hands and feet of affected individuals. The mean age of cases 38.1±14.2 years and 38.9±12.9 years was in control group. Male - female ratio was 3.6: 1. It was observed that 10.7% leprosy patients show...

Bangladesh Medical Journal, 2021

Type 1 diabetes mellitus is one of the most common endocrine and metabolic disorder in children a... more Type 1 diabetes mellitus is one of the most common endocrine and metabolic disorder in children and adolescents. Alteration of serum magnesium level may be associated with metabolic control and diabetic complications. The aim of the study was to evaluate serum magnesium level and find out its relationship with glycemic control in type 1 diabetic children and adolescents. For this study 80 type 1 diabetic children & adolescents with age range 1 to 18 years and 80 aged matched healthy controls were enrolled from the outpatient department of Changing Diabetes in Children, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine & Metabolic disorders, General Hospital, Dhaka. Using a cross sectional design, we measured anthropometric parameters and serum magnesium level of all study subjects. We also estimate the fasting plasma glucose and HbA1c levels of the diabetic children and adolescents and controls. The mean ± SD of serum magnesium level was significantly lower ...

Bangladesh Medical Journal

Psoriasis is a common chronic inflammatory disease of skin and multiple organs of body. The exact... more Psoriasis is a common chronic inflammatory disease of skin and multiple organs of body. The exact etiology of psoriasis is not yet certain. It is assumed that trace elements may have some role in pathogenesis of psoriasis. They can act as co-enzymes for metabolism and can act as antioxidants against free radicals. Therefore they can participate in epidermal proliferation and inflammatory process of psoriasis. This study aimed to evaluate the relation between psoriasis and trace elements namely zinc and copper. This study was conducted on 40 diagnosed cases of psoriasis and 40 non psoriatic individuals in the department of Dermatology and Venereology in Bangabandhu Sheikh Mujib Medical University, Dhaka. Biochemical analyses of serum copper and zinc were analyzed and compared statistically with cases and healthy controls. Serum zinc level was significantly lower and serum copper level was significantly higher in patient with psoriasis compared to control (p= < 0.001). Individuals ...

Community Based Medical Journal

A cross-sectional study was conducted in the Department of Biochemistry and Molecular Biology of ... more A cross-sectional study was conducted in the Department of Biochemistry and Molecular Biology of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh, between July 2016 and June 2017, to evaluate serum zinc level and its relationship with glycemic control in type 1 diabetic children. A total of 160 participants (all aged between 1 and 18 years) were selected from the outpatient department (OPD) of BIRDEM General Hospital-2, Dhaka – 80 type 1 diabetic children as cases and 80 apparently healthy children as controls. We measured anthropometric parameters all study subjects. Serum zinc level was assessed using colorimetric method. Fasting plasma glucose level was estimated using enzymatic glucose-oxidase method. Glycemic control was evaluated through estimation of HbA1c using a high-performance liquid chromatographic method. The mean serum zinc levels were significantly lower in patient with type 1 DM compared to...

Objective This study was designed to establish polymerase chain reaction (PCR) as a more effectiv... more Objective This study was designed to establish polymerase chain reaction (PCR) as a more effective tool for diagnose cutaneous tuberculosis (TB). Methods This cross-sectional study was conducted in the department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, over a duration of one year. Thirty clinically diagnosed patients of cutaneous tuberculosis were selected for this study. The selected skin lesion was biopsied and it was divided in two portions, one for histopathological examination and another for bacteriological Ziehl-Neelsen (Z-N) staining, culture and molecular PCR analysis. Results In our study mean age was found 34.5±16.6 years, male to female ratio was 1.3:1. Tuberculosis verrucosa cutis (43%) was the commonest type of skin TB than lupus vulgaris (30%), erythema induratum of Bazin (13.3%) and others cutaneous types (13.3%). Concomitant pulmonary tuberculosis was detected in 10% of examined patients. In histopatholog...

Bony changes in lepromatous leprosy are one of the causes of deformity and disability. Fasting ca... more Bony changes in lepromatous leprosy are one of the causes of deformity and disability. Fasting calcium and creatinine ratio in urine is used as a bone resorption marker in a number of diseases such as hyperthyroidism, osteoporosis, multiple myeloma, paget’s disease and sarcodosis. In lepromatous leprosy assessment of bone resorption might be done with that marker. To assess the role of fasting urinary calcium and creatinine ratio as a marker of bone resorption in patients with lepromatous leprosy. A case control study was conducted on 28 patients diagnosed as lepromatous leprosy and 28 age-matched healthy control. The participants who fulfilled all inclusion and exclusion criteria were studied by measuring fasting urinary calcium and creatinine level as well as observing X-rays of both hands and feet of affected individuals. The mean age of cases 38.1±14.2 years and 38.9±12.9 years was in control group. Male - female ratio was 3.6: 1. It was observed that 10.7% leprosy patients show...

Bangladesh Medical Journal, 2021

Type 1 diabetes mellitus is one of the most common endocrine and metabolic disorder in children a... more Type 1 diabetes mellitus is one of the most common endocrine and metabolic disorder in children and adolescents. Alteration of serum magnesium level may be associated with metabolic control and diabetic complications. The aim of the study was to evaluate serum magnesium level and find out its relationship with glycemic control in type 1 diabetic children and adolescents. For this study 80 type 1 diabetic children & adolescents with age range 1 to 18 years and 80 aged matched healthy controls were enrolled from the outpatient department of Changing Diabetes in Children, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine & Metabolic disorders, General Hospital, Dhaka. Using a cross sectional design, we measured anthropometric parameters and serum magnesium level of all study subjects. We also estimate the fasting plasma glucose and HbA1c levels of the diabetic children and adolescents and controls. The mean ± SD of serum magnesium level was significantly lower ...