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Research paper thumbnail of Clinico-pathological observations in sheep & goats exposed to lineage III peste des petits ruminants virus infection in Kenya

Journal of Experimental Biology and Agricultural Sciences, 2015

It has been demonstrated that positive tissue samples from an active case in Turkana had viral RN... more It has been demonstrated that positive tissue samples from an active case in Turkana had viral RNA from a lineage III PPRV and the first available genome sequence was determined. Seven goats and sheep aged between 3-6 months that were tested to be negative for PPR antibodies by competitiveELISA were used for study. These animals were divided into two treatment groups and one control group. Each animal in the treatment groups was inoculated through intranasal route with 2ml of 30% infected mixed tissue suspension while the control group was inoculated with phosphate buffered saline. Animals were then examined daily for development of PPR clinical signs. Clinical signs were observed in treatment groups while the control remained apparently healthy. Fever started to develop from 6.6 ±1.14 and 8.6 ±1.34 days post infection (dpi) in goats and sheep respectively. There was a progressive rise in respiratory rates from 9 to 16 dpi in goats and from 9 to 14 dpi in sheep. Nasal discharges wer...

Research paper thumbnail of Experimental infection of PPR in goats in Kenya

Research paper thumbnail of Enhanced diagnosis of peste des petits ruminants (PPR) using experimental infection models

Research paper thumbnail of New Onset Heartburn as a Gastrointestinal Symptom of Severe Malaria

American Journal of Gastroenterology, 2011

Research paper thumbnail of Typhoid Fever

American Journal of Gastroenterology, 2011

Research paper thumbnail of Experimental infection of Peste des petits ruminants disease in Kenya

Research paper thumbnail of Clinico-pathological observations in sheep & goats exposed to lineage III peste des petits ruminants virus infection in Kenya

Journal of Experimental Biology and Agricultural Sciences, 2015

It has been demonstrated that positive tissue samples from an active case in Turkana had viral RN... more It has been demonstrated that positive tissue samples from an active case in Turkana had viral RNA from a lineage III PPRV and the first available genome sequence was determined. Seven goats and sheep aged between 3-6 months that were tested to be negative for PPR antibodies by competitiveELISA were used for study. These animals were divided into two treatment groups and one control group. Each animal in the treatment groups was inoculated through intranasal route with 2ml of 30% infected mixed tissue suspension while the control group was inoculated with phosphate buffered saline. Animals were then examined daily for development of PPR clinical signs. Clinical signs were observed in treatment groups while the control remained apparently healthy. Fever started to develop from 6.6 ±1.14 and 8.6 ±1.34 days post infection (dpi) in goats and sheep respectively. There was a progressive rise in respiratory rates from 9 to 16 dpi in goats and from 9 to 14 dpi in sheep. Nasal discharges wer...

Research paper thumbnail of Experimental infection of PPR in goats in Kenya

Research paper thumbnail of Enhanced diagnosis of peste des petits ruminants (PPR) using experimental infection models

Research paper thumbnail of New Onset Heartburn as a Gastrointestinal Symptom of Severe Malaria

American Journal of Gastroenterology, 2011

Research paper thumbnail of Typhoid Fever

American Journal of Gastroenterology, 2011

Research paper thumbnail of Experimental infection of Peste des petits ruminants disease in Kenya

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