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Papers by sinan rusinovci

Research paper thumbnail of Rates of tumour recurrences and metastases after surgical removal of malignant salivary gland tumours throughout 5-years of follow-up: A retrospective single-centre study

Oral and Maxillofacial Surgery Cases, Sep 1, 2019

The purpose of the current study was to evaluate the frequency rates of tumour recurrences and ra... more The purpose of the current study was to evaluate the frequency rates of tumour recurrences and rates of metastases in patients with surgical removal of malignant salivary gland tumours throughout 5 years of follow-up after initial therapy, and determine which salivary gland and histological diagnosis are the major contributors for the occurrence. Methods: Between 2005 and 2017, 74 patients underwent surgical removal of localized malignant cancers of the salivary glands. Data were analysed retrospectively from our tertiary hospital database. The demographic characteristics (age and gender) were obtained from the patients' records. Pearson's χ-square test and logistic regression were used to analyse the data with p < 0.05 as statistically significant. Results: Malignant salivary gland tumours were mostly diagnosed at parotid gland in 51.4% of cases, thus majority of patients underwent surgical extirpation (37.8% of cases) of tumour removal. Adenocarcinoma was the most common form of malignancy (19 patients, 25.6%), followed by adenoid cystic carcinoma (13 patients 17.6%) and mucoepidermoid carcinoma (11 patients, 14.9%). Postoperative complications; namely tumour recurrences were detected in 8 patients (10.8%) throughout 5 years of follow-up after initial therapy. Metastases were observed in 6 patients (8.1%), and facial nerve paralyses were diagnosed in 19 (25.7%) of all patients and with no specific risk factors, that could have contributed to the occurrence of nerve damage. Conclusions: A significant proportion of patients who are presumed to be cured of their disease through 5 years after initial treatment for salivary gland cancer will be found to develop late disease recurrences or metastases.

Research paper thumbnail of Dental Health and Quality of Life in 117 Patients from Kosovo, Aged 6-80 Years, Evaluated Using the Dental Impact on Daily Living (DIDL) Questionnaire and the Oral Health-Related Quality of Life (OHRQoL) Questionnaire

Medical Science Monitor, Sep 5, 2022

BackgroundThis study aimed to evaluate the effects of dental health on quality of life (QoL) in 1... more BackgroundThis study aimed to evaluate the effects of dental health on quality of life (QoL) in 117 patients from Kosova, aged 6–80 years, using the Dental Impact on Daily Living (DL) questionnaire and the Oral Health-Related Quality of Life (OHRQoL) questionnaire.Material/MethodsWe recruited 117 patients, approximately half male and half female, aged 6–80 years. The subjects came for dental appointments and filled out 2 questionnaires: DIDL addressing questions on appearance, comfort, pain, performance and eating restriction, and OHRQoL assessing dental-specific questions for evaluation of satisfaction with oral health, and evaluation of importance they attribute to oral health. Collected data included age, gender, income, education level, and frequency of brushing teeth per day.ResultsThe participants were relatively satisfied with their DIDL health (score >0) and also had positive views on OHRQoL (score >0). No participants evaluated the appearance, comfort, eating restrictions, or pain as satisfactory. Comparisons of age, gender, education, income level, and frequency of brushing teeth showed that female participants evaluated their DIDL higher than male participants (P=0.043). Age was correlated with the frequency of teeth brushing per day (rho=−0.450; P<0.001). Gender, age, education level, income level, and frequency of teeth brushing did not influence QoL.ConclusionsThis small study from Kosovo showed reasonable satisfaction with oral health and its associated QoL. While participants reported good effects of oral health on their QoL, they were least satisfied with comfort and most satisfied with their performance.

Research paper thumbnail of P.330 Metastatic basal cell carcinoma – case report

Journal of Cranio-Maxillofacial Surgery, 2008

Research paper thumbnail of Analysis of Three-Year Prevalence of Oral Cavity, Neck and Head Tumors – a Retrospective Single-Centre Study

Acta Clinica Croatica, 2020

The purpose of the study was to retrospectively analyze the prevalence of oral cavity, neck and h... more The purpose of the study was to retrospectively analyze the prevalence of oral cavity, neck and head tumors recorded at our department over a period of 3 years. Retrospective analysis included archival data on cancer patients treated at our department during the 2015-2017 period. A total of 1005 patients with proven carcinomas were selected for final analysis. Cancers were detected by ultrasound, x-ray, biopsy and clinical diagnosis. The mean age of patients was 58.4±19.3 years. The majority of cases (n=264; 26.3%) were detected in the 7 th decade of life. The most common cancers were basal cell carcinoma in 374 (37.2%) and squamous cell carcinoma in 228 (22.7%) cases. The male-to-female ratio was 1.7:1. There was no statistically significant age difference between genders. Recurrence of tumor occurred in 31 patients. The most common risk factor in both groups was sun exposure. The most common sites were lower lip, cheek and frontal region in men, and cheek region and nose in women (p<0.001). men were found to be more susceptible to cancer development. This study showed differences between age groups, i.e. el derly patients had a much higher probability of developing cancer as compared to younger patients.

Research paper thumbnail of Tumour Recurrence and Facial Nerve Injury Rates After Surgery of Pleomorphic Adenoma Through 5-Year Follow-Up : A Retrospective Single-Centre Study

According to the guidelines for the treatment of pleomorphic adenoma of parotid gland patients sh... more According to the guidelines for the treatment of pleomorphic adenoma of parotid gland patients should undergo superficial parotidectomy. The aim of our study was to compare facial nerve injury rates and tumour recurrence rates after superficial parotidectomy vs. tumour extirpation as an alternative procedure of treatment. Study was conducted as a retrospective analysis of the data from patients, who underwent different surgeries of pleomorphic adenoma removal in our university centre between 2005 till 2017 and were followed up for 5 years after the procedure. The major independent variables were superficial parotidectomy or extirpation, and the main outcome parameter was diagnosis of facial nerve injury or tumour recurrence. Overall 161 cases of surgical removal of pleomorphic adenomas were analysed. Mean age of patients was 47.9±19.5 years. The male-to-female ratio was 1:1.04 with no significant differences between genders. Adenoma pleomorphe as diagnosis was mostly found at paroti...

Research paper thumbnail of Evaluation of Questionnaires to Assess Dental Trauma And Anxiety of Children in Kosovo

Dental trauma relates to negative consequences that the child links to negative experience. The a... more Dental trauma relates to negative consequences that the child links to negative experience. The aim of this study was to assess the scale of dental anxiety in children with dental trauma and to evaluate the questionnaires as measurement scales which handle the trauma and anxiety parameters. Study included 505 patients, aged 7 to 14 years of whom 254 children experienced dental trauma and 251 children were without dental trauma experience. The subjects came for dental appointment from 2015 to 2016 and filled out the questionnaires about anxiety. The following questionnaires were used: CFSS-DS, CDAS, CMFQ, S-DAI and DVSS-SV. The Cronbach alpha was used to check the reliability and validity of the questionnaires. Larger percentage of cases had lower scale of dental anxiety. Meanwhile high scale dental anxiety was proportionally higher in the group with dental trauma for all questionnaires. Dental visit satisfaction scale was higher in the group without dental trauma. Female patients sh...

Research paper thumbnail of Salivary Gland Tumours Through 5-Year Follow-Up : A Retrospective Single-Centre Study

The aim of our study was to analyse the prevalence of salivary gland tumours through 5-years of f... more The aim of our study was to analyse the prevalence of salivary gland tumours through 5-years of follow-up. Study was designed as a retrospective analysis of patients, who underwent surgery of tumour removal in our centre between 2005 till 2017 and were followed up for 5 years. The demographic characteristics (age and gender) were obtained from 247 patient records. Pearson’s χ-square test and logistic regression were used to analyse the data, where p<0.05 was considered as statistically significant. Overall 247 cases were analysed and followed up for 5 years after surgical removal of tumours. Mean age of patients was 51.0±19.5 years. The male-to-female ratio was 1.1:1. Female patients were statistically younger compared to male patients (p=0.017). The most common tumour was found at parotid gland in 154 (62.3%) cases. Adenoma pleomorphe was diagnosed in 125 (50.6%) cases. Superficial parotidectomy was performed in 44 (17.8%), and surgical extirpation in 143 (57.9%) cases. Recurren...

Research paper thumbnail of Clinical and hystopathological dilemmas in diagnosis of epitheloid hemangioma of maxillae-case report

International Journal of Dental Research and Reviews, 2018

Clinical and hystopathological dilemmas in diagnosis of epitheloid hemangioma of maxillae-case re... more Clinical and hystopathological dilemmas in diagnosis of epitheloid hemangioma of maxillae-case report Epithelioid hemangioma (EH) is a rare benign tumor involving the blood vessels and surrounding epithelioid cells. Epitheloid hemangioma, also called histiocytoid hemangioma, angiolymphoid hyperplasia with eosinophilia (ALHE), is a very rare benign tumor in maxillofacial region. There is a controversy in regards to correct diagnosis of an epithelioid hemangioma (EH), particularly when arising in skeletal locations, because of aggressive clinical characteristics, including multifocal presentation and occasional lymph node involvement. Specifically, its distinction from epithelioid hemangio-endothelioma (EHE) has been controversial. In literature we did not find a case where EH involves maxilla. However, there are few cases reported in which EH involved maxillary sinus and nasal cavity. We will present a case of 21 year old male, who came to our Department with a lesion in frontal maxillary region. He underwent surgery four times, wide excision, and with four different histopathology results. The last result was ephiteloid hemangioma with metaplastic bone formation-a very rare benign lesion in oral region, but clinically with very aggressive nature.

Research paper thumbnail of Bacteria That Cause Dentoalveolar Abscesses after Failed Endodontic Treatments : A Pilot Study

Failed endodontic treatments often lead to more severe conditions that need surgical procedures. ... more Failed endodontic treatments often lead to more severe conditions that need surgical procedures. The aim of this study was to identify which microorganisms caused dental abscesses. 50 pus samples from patients with dental abscesses were examined for bacterial growth and 50 samples from healthy gingiva of healthy individuals were swabbed for comparison of bacterial etiology. Isolated pathogenic bacterial were compared and bacteria were identified using MALDITOF. Bacterial strains were positively identified in 42 out of 50 patients with dental abscesses. 16 different microorganisms from 100 subjects (patients with dentoalveolar abscesses and controls) were isolated. In 18 (36.0%) out of the 50 samples only aerobic flora was present, in 10 (20.0%) out of 50 only strictly anaerobic flora, and in 22 (44.0%) out of 50 abscesses mixed aerobic anaerobic flora was isolated. Isolated oral microorganisms in our study did not vary with significance compared to healthy oral microbiota, thus comm...

Research paper thumbnail of Analysis of THREE-year prevalence of oral cavity, neck and head tumors – a retrospective single-centre study

SUMMARY The purpose of the study was to retrospectively analyze the prevalence of oral cavity, ne... more SUMMARY The purpose of the study was to retrospectively analyze the prevalence of oral cavity, neck and head tumors recorded at our department over a period of 3 years. Retrospective analysis included archival data on cancer patients treated at our department during the 2015-2017 period. A total of 1005 patients with proven carcinomas were selected for final analysis. Cancers were detected by ultrasound, x-ray, biopsy and clinical diagnosis. The mean age of patients was 58.4±19.3 years. The majority of cases (n=264; 26.3%) were detected in the 7th decade of life. The most common cancers were basal cell carcinoma in 374 (37.2%) and squamous cell carcinoma in 228 (22.7%) cases. The male-to-female ratio was 1.7:1. There was no statistically significant age difference between genders. Recurrence of tumor occurred in 31 patients. The most common risk factor in both groups was sun exposure. The most common sites were lower lip, cheek and frontal region in men, and cheek region and nose in...

Research paper thumbnail of Detection of Occult Metastases in Patients with T1 and T2 Stage Lower Lip Squamous Cell Carcinomas after Positive Lymphoscintigraphy

Diagnostics, Feb 11, 2020

The aim of this study was to detect lower lip squamous cell carcinomas (SCC) that had metastasize... more The aim of this study was to detect lower lip squamous cell carcinomas (SCC) that had metastasized to the lymph nodes and to evaluate if neck dissection was necessary for patients with T1 or T2-stage lip cancer after a sentinel lymph node biopsy (SLNB). The study was conducted as a prospective clinical study to detect occult neck metastases in patients with T1 or T2 stage SCC of the lower lip. Thirty-one patients were eligible and underwent echo-ultrasound, computer tomography, magnetic resonance and lymphoscintigraphy (LSG) as diagnostic procedures. LSG was performed on the same day as the surgical procedure, after intradermal injection of 37 Mbq Tc99m-Sn-colloid/mL at four peritumoral sites. In patients with positive LSG results, the sentinel lymph nodes were extracted surgically. The risk factors for cancer development were sun exposure and smoking. The highest accuracy for detecting lymph node enlargements was achieved with magnetic resonance imaging (MRI; 80.7%). LSG showed excellent sensitivity (100%) and negative predictive value (NPV; 100%). Overall, occult metastases were diagnosed with an SLNB in eight (25.8%) patients. According to the results, with great caution, we suggest that an SLNB is reasonable to initiate only for patients with positive sentinel nodes by positive LSG, to be used as a lower morbidity approach for selected patients with T1 and T2 stage cancers.

Research paper thumbnail of Rates of tumour recurrences and metastases after surgical removal of malignant salivary gland tumours throughout 5-years of follow-up: a retrospective single-centre study

Oral and Maxillofacial Surgery Cases

Abstract Purpose The purpose of the current study was to evaluate the frequency rates of tumour r... more Abstract Purpose The purpose of the current study was to evaluate the frequency rates of tumour recurrences and rates of metastases in patients with surgical removal of malignant salivary gland tumours throughout 5 years of follow-up after initial therapy, and determine which salivary gland and histological diagnosis are the major contributors for the occurrence. Methods Between 2005 and 2017, 74 patients underwent surgical removal of localized malignant cancers of the salivary glands. Data were analysed retrospectively from our tertiary hospital database. The demographic characteristics (age and gender) were obtained from the patients' records. Pearson's χ-square test and logistic regression were used to analyse the data with p Results Malignant salivary gland tumours were mostly diagnosed at parotid gland in 51.4% of cases, thus majority of patients underwent surgical extirpation (37.8% of cases) of tumour removal. Adenocarcinoma was the most common form of malignancy (19 patients, 25.6%), followed by adenoid cystic carcinoma (13 patients 17.6%) and mucoepidermoid carcinoma (11 patients, 14.9%). Postoperative complications; namely tumour recurrences were detected in 8 patients (10.8%) throughout 5 years of follow-up after initial therapy. Metastases were observed in 6 patients (8.1%), and facial nerve paralyses were diagnosed in 19 (25.7%) of all patients and with no specific risk factors, that could have contributed to the occurrence of nerve damage. Conclusions A significant proportion of patients who are presumed to be cured of their disease through 5 years after initial treatment for salivary gland cancer will be found to develop late disease recurrences or metastases.

Research paper thumbnail of P.299 Trends in the etiology of maxillofacial fractures in Kosova

Journal of Cranio-Maxillofacial Surgery, 2008

Research paper thumbnail of Rates of tumour recurrences and metastases after surgical removal of malignant salivary gland tumours throughout 5-years of follow-up: A retrospective single-centre study

Oral and Maxillofacial Surgery Cases, Sep 1, 2019

The purpose of the current study was to evaluate the frequency rates of tumour recurrences and ra... more The purpose of the current study was to evaluate the frequency rates of tumour recurrences and rates of metastases in patients with surgical removal of malignant salivary gland tumours throughout 5 years of follow-up after initial therapy, and determine which salivary gland and histological diagnosis are the major contributors for the occurrence. Methods: Between 2005 and 2017, 74 patients underwent surgical removal of localized malignant cancers of the salivary glands. Data were analysed retrospectively from our tertiary hospital database. The demographic characteristics (age and gender) were obtained from the patients' records. Pearson's χ-square test and logistic regression were used to analyse the data with p < 0.05 as statistically significant. Results: Malignant salivary gland tumours were mostly diagnosed at parotid gland in 51.4% of cases, thus majority of patients underwent surgical extirpation (37.8% of cases) of tumour removal. Adenocarcinoma was the most common form of malignancy (19 patients, 25.6%), followed by adenoid cystic carcinoma (13 patients 17.6%) and mucoepidermoid carcinoma (11 patients, 14.9%). Postoperative complications; namely tumour recurrences were detected in 8 patients (10.8%) throughout 5 years of follow-up after initial therapy. Metastases were observed in 6 patients (8.1%), and facial nerve paralyses were diagnosed in 19 (25.7%) of all patients and with no specific risk factors, that could have contributed to the occurrence of nerve damage. Conclusions: A significant proportion of patients who are presumed to be cured of their disease through 5 years after initial treatment for salivary gland cancer will be found to develop late disease recurrences or metastases.

Research paper thumbnail of Dental Health and Quality of Life in 117 Patients from Kosovo, Aged 6-80 Years, Evaluated Using the Dental Impact on Daily Living (DIDL) Questionnaire and the Oral Health-Related Quality of Life (OHRQoL) Questionnaire

Medical Science Monitor, Sep 5, 2022

BackgroundThis study aimed to evaluate the effects of dental health on quality of life (QoL) in 1... more BackgroundThis study aimed to evaluate the effects of dental health on quality of life (QoL) in 117 patients from Kosova, aged 6–80 years, using the Dental Impact on Daily Living (DL) questionnaire and the Oral Health-Related Quality of Life (OHRQoL) questionnaire.Material/MethodsWe recruited 117 patients, approximately half male and half female, aged 6–80 years. The subjects came for dental appointments and filled out 2 questionnaires: DIDL addressing questions on appearance, comfort, pain, performance and eating restriction, and OHRQoL assessing dental-specific questions for evaluation of satisfaction with oral health, and evaluation of importance they attribute to oral health. Collected data included age, gender, income, education level, and frequency of brushing teeth per day.ResultsThe participants were relatively satisfied with their DIDL health (score >0) and also had positive views on OHRQoL (score >0). No participants evaluated the appearance, comfort, eating restrictions, or pain as satisfactory. Comparisons of age, gender, education, income level, and frequency of brushing teeth showed that female participants evaluated their DIDL higher than male participants (P=0.043). Age was correlated with the frequency of teeth brushing per day (rho=−0.450; P<0.001). Gender, age, education level, income level, and frequency of teeth brushing did not influence QoL.ConclusionsThis small study from Kosovo showed reasonable satisfaction with oral health and its associated QoL. While participants reported good effects of oral health on their QoL, they were least satisfied with comfort and most satisfied with their performance.

Research paper thumbnail of P.330 Metastatic basal cell carcinoma – case report

Journal of Cranio-Maxillofacial Surgery, 2008

Research paper thumbnail of Analysis of Three-Year Prevalence of Oral Cavity, Neck and Head Tumors – a Retrospective Single-Centre Study

Acta Clinica Croatica, 2020

The purpose of the study was to retrospectively analyze the prevalence of oral cavity, neck and h... more The purpose of the study was to retrospectively analyze the prevalence of oral cavity, neck and head tumors recorded at our department over a period of 3 years. Retrospective analysis included archival data on cancer patients treated at our department during the 2015-2017 period. A total of 1005 patients with proven carcinomas were selected for final analysis. Cancers were detected by ultrasound, x-ray, biopsy and clinical diagnosis. The mean age of patients was 58.4±19.3 years. The majority of cases (n=264; 26.3%) were detected in the 7 th decade of life. The most common cancers were basal cell carcinoma in 374 (37.2%) and squamous cell carcinoma in 228 (22.7%) cases. The male-to-female ratio was 1.7:1. There was no statistically significant age difference between genders. Recurrence of tumor occurred in 31 patients. The most common risk factor in both groups was sun exposure. The most common sites were lower lip, cheek and frontal region in men, and cheek region and nose in women (p<0.001). men were found to be more susceptible to cancer development. This study showed differences between age groups, i.e. el derly patients had a much higher probability of developing cancer as compared to younger patients.

Research paper thumbnail of Tumour Recurrence and Facial Nerve Injury Rates After Surgery of Pleomorphic Adenoma Through 5-Year Follow-Up : A Retrospective Single-Centre Study

According to the guidelines for the treatment of pleomorphic adenoma of parotid gland patients sh... more According to the guidelines for the treatment of pleomorphic adenoma of parotid gland patients should undergo superficial parotidectomy. The aim of our study was to compare facial nerve injury rates and tumour recurrence rates after superficial parotidectomy vs. tumour extirpation as an alternative procedure of treatment. Study was conducted as a retrospective analysis of the data from patients, who underwent different surgeries of pleomorphic adenoma removal in our university centre between 2005 till 2017 and were followed up for 5 years after the procedure. The major independent variables were superficial parotidectomy or extirpation, and the main outcome parameter was diagnosis of facial nerve injury or tumour recurrence. Overall 161 cases of surgical removal of pleomorphic adenomas were analysed. Mean age of patients was 47.9±19.5 years. The male-to-female ratio was 1:1.04 with no significant differences between genders. Adenoma pleomorphe as diagnosis was mostly found at paroti...

Research paper thumbnail of Evaluation of Questionnaires to Assess Dental Trauma And Anxiety of Children in Kosovo

Dental trauma relates to negative consequences that the child links to negative experience. The a... more Dental trauma relates to negative consequences that the child links to negative experience. The aim of this study was to assess the scale of dental anxiety in children with dental trauma and to evaluate the questionnaires as measurement scales which handle the trauma and anxiety parameters. Study included 505 patients, aged 7 to 14 years of whom 254 children experienced dental trauma and 251 children were without dental trauma experience. The subjects came for dental appointment from 2015 to 2016 and filled out the questionnaires about anxiety. The following questionnaires were used: CFSS-DS, CDAS, CMFQ, S-DAI and DVSS-SV. The Cronbach alpha was used to check the reliability and validity of the questionnaires. Larger percentage of cases had lower scale of dental anxiety. Meanwhile high scale dental anxiety was proportionally higher in the group with dental trauma for all questionnaires. Dental visit satisfaction scale was higher in the group without dental trauma. Female patients sh...

Research paper thumbnail of Salivary Gland Tumours Through 5-Year Follow-Up : A Retrospective Single-Centre Study

The aim of our study was to analyse the prevalence of salivary gland tumours through 5-years of f... more The aim of our study was to analyse the prevalence of salivary gland tumours through 5-years of follow-up. Study was designed as a retrospective analysis of patients, who underwent surgery of tumour removal in our centre between 2005 till 2017 and were followed up for 5 years. The demographic characteristics (age and gender) were obtained from 247 patient records. Pearson’s χ-square test and logistic regression were used to analyse the data, where p<0.05 was considered as statistically significant. Overall 247 cases were analysed and followed up for 5 years after surgical removal of tumours. Mean age of patients was 51.0±19.5 years. The male-to-female ratio was 1.1:1. Female patients were statistically younger compared to male patients (p=0.017). The most common tumour was found at parotid gland in 154 (62.3%) cases. Adenoma pleomorphe was diagnosed in 125 (50.6%) cases. Superficial parotidectomy was performed in 44 (17.8%), and surgical extirpation in 143 (57.9%) cases. Recurren...

Research paper thumbnail of Clinical and hystopathological dilemmas in diagnosis of epitheloid hemangioma of maxillae-case report

International Journal of Dental Research and Reviews, 2018

Clinical and hystopathological dilemmas in diagnosis of epitheloid hemangioma of maxillae-case re... more Clinical and hystopathological dilemmas in diagnosis of epitheloid hemangioma of maxillae-case report Epithelioid hemangioma (EH) is a rare benign tumor involving the blood vessels and surrounding epithelioid cells. Epitheloid hemangioma, also called histiocytoid hemangioma, angiolymphoid hyperplasia with eosinophilia (ALHE), is a very rare benign tumor in maxillofacial region. There is a controversy in regards to correct diagnosis of an epithelioid hemangioma (EH), particularly when arising in skeletal locations, because of aggressive clinical characteristics, including multifocal presentation and occasional lymph node involvement. Specifically, its distinction from epithelioid hemangio-endothelioma (EHE) has been controversial. In literature we did not find a case where EH involves maxilla. However, there are few cases reported in which EH involved maxillary sinus and nasal cavity. We will present a case of 21 year old male, who came to our Department with a lesion in frontal maxillary region. He underwent surgery four times, wide excision, and with four different histopathology results. The last result was ephiteloid hemangioma with metaplastic bone formation-a very rare benign lesion in oral region, but clinically with very aggressive nature.

Research paper thumbnail of Bacteria That Cause Dentoalveolar Abscesses after Failed Endodontic Treatments : A Pilot Study

Failed endodontic treatments often lead to more severe conditions that need surgical procedures. ... more Failed endodontic treatments often lead to more severe conditions that need surgical procedures. The aim of this study was to identify which microorganisms caused dental abscesses. 50 pus samples from patients with dental abscesses were examined for bacterial growth and 50 samples from healthy gingiva of healthy individuals were swabbed for comparison of bacterial etiology. Isolated pathogenic bacterial were compared and bacteria were identified using MALDITOF. Bacterial strains were positively identified in 42 out of 50 patients with dental abscesses. 16 different microorganisms from 100 subjects (patients with dentoalveolar abscesses and controls) were isolated. In 18 (36.0%) out of the 50 samples only aerobic flora was present, in 10 (20.0%) out of 50 only strictly anaerobic flora, and in 22 (44.0%) out of 50 abscesses mixed aerobic anaerobic flora was isolated. Isolated oral microorganisms in our study did not vary with significance compared to healthy oral microbiota, thus comm...

Research paper thumbnail of Analysis of THREE-year prevalence of oral cavity, neck and head tumors – a retrospective single-centre study

SUMMARY The purpose of the study was to retrospectively analyze the prevalence of oral cavity, ne... more SUMMARY The purpose of the study was to retrospectively analyze the prevalence of oral cavity, neck and head tumors recorded at our department over a period of 3 years. Retrospective analysis included archival data on cancer patients treated at our department during the 2015-2017 period. A total of 1005 patients with proven carcinomas were selected for final analysis. Cancers were detected by ultrasound, x-ray, biopsy and clinical diagnosis. The mean age of patients was 58.4±19.3 years. The majority of cases (n=264; 26.3%) were detected in the 7th decade of life. The most common cancers were basal cell carcinoma in 374 (37.2%) and squamous cell carcinoma in 228 (22.7%) cases. The male-to-female ratio was 1.7:1. There was no statistically significant age difference between genders. Recurrence of tumor occurred in 31 patients. The most common risk factor in both groups was sun exposure. The most common sites were lower lip, cheek and frontal region in men, and cheek region and nose in...

Research paper thumbnail of Detection of Occult Metastases in Patients with T1 and T2 Stage Lower Lip Squamous Cell Carcinomas after Positive Lymphoscintigraphy

Diagnostics, Feb 11, 2020

The aim of this study was to detect lower lip squamous cell carcinomas (SCC) that had metastasize... more The aim of this study was to detect lower lip squamous cell carcinomas (SCC) that had metastasized to the lymph nodes and to evaluate if neck dissection was necessary for patients with T1 or T2-stage lip cancer after a sentinel lymph node biopsy (SLNB). The study was conducted as a prospective clinical study to detect occult neck metastases in patients with T1 or T2 stage SCC of the lower lip. Thirty-one patients were eligible and underwent echo-ultrasound, computer tomography, magnetic resonance and lymphoscintigraphy (LSG) as diagnostic procedures. LSG was performed on the same day as the surgical procedure, after intradermal injection of 37 Mbq Tc99m-Sn-colloid/mL at four peritumoral sites. In patients with positive LSG results, the sentinel lymph nodes were extracted surgically. The risk factors for cancer development were sun exposure and smoking. The highest accuracy for detecting lymph node enlargements was achieved with magnetic resonance imaging (MRI; 80.7%). LSG showed excellent sensitivity (100%) and negative predictive value (NPV; 100%). Overall, occult metastases were diagnosed with an SLNB in eight (25.8%) patients. According to the results, with great caution, we suggest that an SLNB is reasonable to initiate only for patients with positive sentinel nodes by positive LSG, to be used as a lower morbidity approach for selected patients with T1 and T2 stage cancers.

Research paper thumbnail of Rates of tumour recurrences and metastases after surgical removal of malignant salivary gland tumours throughout 5-years of follow-up: a retrospective single-centre study

Oral and Maxillofacial Surgery Cases

Abstract Purpose The purpose of the current study was to evaluate the frequency rates of tumour r... more Abstract Purpose The purpose of the current study was to evaluate the frequency rates of tumour recurrences and rates of metastases in patients with surgical removal of malignant salivary gland tumours throughout 5 years of follow-up after initial therapy, and determine which salivary gland and histological diagnosis are the major contributors for the occurrence. Methods Between 2005 and 2017, 74 patients underwent surgical removal of localized malignant cancers of the salivary glands. Data were analysed retrospectively from our tertiary hospital database. The demographic characteristics (age and gender) were obtained from the patients' records. Pearson's χ-square test and logistic regression were used to analyse the data with p Results Malignant salivary gland tumours were mostly diagnosed at parotid gland in 51.4% of cases, thus majority of patients underwent surgical extirpation (37.8% of cases) of tumour removal. Adenocarcinoma was the most common form of malignancy (19 patients, 25.6%), followed by adenoid cystic carcinoma (13 patients 17.6%) and mucoepidermoid carcinoma (11 patients, 14.9%). Postoperative complications; namely tumour recurrences were detected in 8 patients (10.8%) throughout 5 years of follow-up after initial therapy. Metastases were observed in 6 patients (8.1%), and facial nerve paralyses were diagnosed in 19 (25.7%) of all patients and with no specific risk factors, that could have contributed to the occurrence of nerve damage. Conclusions A significant proportion of patients who are presumed to be cured of their disease through 5 years after initial treatment for salivary gland cancer will be found to develop late disease recurrences or metastases.

Research paper thumbnail of P.299 Trends in the etiology of maxillofacial fractures in Kosova

Journal of Cranio-Maxillofacial Surgery, 2008