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About 9.6% of infants are born prematurely around the world. In addition to infection of reproduc... more About 9.6% of infants are born prematurely around the world. In addition to infection of reproductive system, inflammation and infection of distant organs are one of the risk factors for preterm low birth weight (PTLBW). Since periodontitis is a prevalent disease and also premature labor is a common complication with high treatment cost, it is important to elucidate the relationship between these two conditions. Such a knowledge could be helpful to prioritize the preventive interventions for reduction of adverse pregnancy outcome. Epidemiologic studies , as the first line of evidence, showed the higher prevalence of PTLBW among women with periodontitis. When a condition is being proposed as a risk factor, it is necessary to explain the biologic mechanisms underlying such a relationship. The relationship between periodontitis and PTLBW is biologically plausible. Periodontitis is a chronic inflammatory disease in which anaerobic bacteria being colonized in deep pathologic pockets and ...
About 9.6% of infants are born prematurely around the world. In addition to infection of reproduc... more About 9.6% of infants are born prematurely around the world. In addition to infection of reproductive system, inflammation and infection of distant organs are one of the risk factors for preterm low birth weight (PTLBW). Since periodontitis is a prevalent disease and also premature labor is a common complication with high treatment cost, it is important to elucidate the relationship between these two conditions. Such a knowledge could be helpful to prioritize the preventive interventions for reduction of adverse pregnancy outcome. Epidemiologic studies , as the first line of evidence, showed the higher prevalence of PTLBW among women with periodontitis. When a condition is being proposed as a risk factor, it is necessary to explain the biologic mechanisms underlying such a relationship. The relationship between periodontitis and PTLBW is biologically plausible. Periodontitis is a chronic inflammatory disease in which anaerobic bacteria being colonized in deep pathologic pockets and ...