snehal anturlikar - Academia.edu (original) (raw)

Papers by snehal anturlikar

Research paper thumbnail of Antimicrobial Resistance Demonstrated by Uropathogenic Escherichia Coli at a Tertiary Care Hospital

International journal of current research and review, Aug 10, 2016

Background: Urinary tract infection (UTI) is one of the most common bacterial infections encounte... more Background: Urinary tract infection (UTI) is one of the most common bacterial infections encountered by clinicians in developing countries. Escherichia coli is the most common causative organism of UTI. Development of resistance by E.coli towards different antimicrobial agents is alarming. Hence, our study was planned to analyze the antimicrobial resistance pattern of E.coli isolates at a tertiary care teaching hospital. Materials and method: Culture sensitivity reports of all urine samples sent to microbiology department of a tertiary care teaching hospital during the period of July 2010-June 2013 were screened. Detailed reports were collected for all the samples in which E.coli was identified as a causative organism. Culture sensitivity testing was done by modified Kirby-Bauer disk diffusion (high media) method. Result: E.coli was isolated in total 1155 urine samples during the period of three years. Majority of patients belonged to pediatric age group (823/1155, 71.25%). 52.21% samples were of female patients. Thirty-one antimicrobial agents were tested for 13048 times for their sensitivity towards E.coli. Antimicrobial resistance ranging from 14.58% to 100% was noted among various antimicrobials. E.coli showed 38.23% resistance towards aminoglycosides, 52.27% resistance towards quinolones, 54.95% resistance towards beta-lactams and 67.33% resistance towards miscellaneous group of antimicrobials. Conclusion: Proper selection and wise use of available antibiotics will help in reducing the rate of increase in resistance. Periodic monitoring of antimicrobial susceptibility pattern of causative agent in a particular setting will be helpful in guiding judicious use of antimicrobial agents limiting the spread of resistant strains.

Research paper thumbnail of Adverse drug reactions reporting by undergraduate medical students in a tertiary care teaching hospital of India: Content and quality analysis in comparison to physician reporting

DOAJ (DOAJ: Directory of Open Access Journals), Aug 23, 2017

An important challenge to spontaneous reporting system is underreporting. The sensitization and i... more An important challenge to spontaneous reporting system is underreporting. The sensitization and involvement of undergraduate medical students can reduce underreporting in pharmacovigilance program. To analyze the clinical characteristics and reporting quality of adverse drug reactions (ADRs) by undergraduate medical students in comparison with physicians' reporting. We sensitized the second professional year undergraduate medical students about pharmacovigilance and asked them to submit reports of ADR observed during their clinical posting from January to December 2015. We compared students' reports with those sent by physicians (Department of Medicine and Allied Branches, Paediatric, Obstetrics and Gynaecology) of our institute during the same time period. We included ADRs of "certain," "probable," or "possible" categories as per the World Health Organization causality definitions in analysis of both groups. We excluded "unlikely," "unclassified," and "unclassifiable" causality ADRs from the analysis due to questionable association of reactions with suspected drugs. We collected data of demographics, pattern of ADRs, causative drugs, seriousness, other clinical characteristics, and quality of reporting. We analyzed a total number of 176 students' reports having 269 ADRs and 143 physicians' reports covering 180 ADRs. The students predominantly reported ADRs of single drug suspect (84.09% vs. 43.35%), "probable" causality (63.94% vs. 21.11), and augmented type reactions (67.29% vs. 55%) than physicians. Both groups did not differ in reporting of serious reactions (6.25% vs. 9.09%). Students most frequently suspected gastrointestinal disorders (35.68%), whereas physicians most frequently reported skin and appendages disorders (41.11%). Students and physicians more commonly suspected ADRs due to systemic anti-infective (33.64%) and nervous system (42.07%) class of drugs, respectively. The quality analysis suggested no substantial difference in most domains of ADR reporting among both groups. Students' reported valuable and clinically relevant ADRs. Medical students should be exposed to ADR reporting during their clinical teaching posting and should be actively involved in pharmacovigilance program to improve detection rate.

Research paper thumbnail of Adverse drug reactions reporting by undergraduate medical students in a tertiary care teaching hospital of India: Content and quality analysis in comparison to physician reporting

Perspectives in clinical research

An important challenge to spontaneous reporting system is underreporting. The sensitization and i... more An important challenge to spontaneous reporting system is underreporting. The sensitization and involvement of undergraduate medical students can reduce underreporting in pharmacovigilance program. To analyze the clinical characteristics and reporting quality of adverse drug reactions (ADRs) by undergraduate medical students in comparison with physicians' reporting. We sensitized the second professional year undergraduate medical students about pharmacovigilance and asked them to submit reports of ADR observed during their clinical posting from January to December 2015. We compared students' reports with those sent by physicians (Department of Medicine and Allied Branches, Paediatric, Obstetrics and Gynaecology) of our institute during the same time period. We included ADRs of "certain," "probable," or "possible" categories as per the World Health Organization causality definitions in analysis of both groups. We excluded "unlikely," &q...

Research paper thumbnail of Antimicrobial Resistance Demonstrated by Uropathogenic Escherichia Coli at a Tertiary Care Hospital

International journal of current research and review, Aug 10, 2016

Background: Urinary tract infection (UTI) is one of the most common bacterial infections encounte... more Background: Urinary tract infection (UTI) is one of the most common bacterial infections encountered by clinicians in developing countries. Escherichia coli is the most common causative organism of UTI. Development of resistance by E.coli towards different antimicrobial agents is alarming. Hence, our study was planned to analyze the antimicrobial resistance pattern of E.coli isolates at a tertiary care teaching hospital. Materials and method: Culture sensitivity reports of all urine samples sent to microbiology department of a tertiary care teaching hospital during the period of July 2010-June 2013 were screened. Detailed reports were collected for all the samples in which E.coli was identified as a causative organism. Culture sensitivity testing was done by modified Kirby-Bauer disk diffusion (high media) method. Result: E.coli was isolated in total 1155 urine samples during the period of three years. Majority of patients belonged to pediatric age group (823/1155, 71.25%). 52.21% samples were of female patients. Thirty-one antimicrobial agents were tested for 13048 times for their sensitivity towards E.coli. Antimicrobial resistance ranging from 14.58% to 100% was noted among various antimicrobials. E.coli showed 38.23% resistance towards aminoglycosides, 52.27% resistance towards quinolones, 54.95% resistance towards beta-lactams and 67.33% resistance towards miscellaneous group of antimicrobials. Conclusion: Proper selection and wise use of available antibiotics will help in reducing the rate of increase in resistance. Periodic monitoring of antimicrobial susceptibility pattern of causative agent in a particular setting will be helpful in guiding judicious use of antimicrobial agents limiting the spread of resistant strains.

Research paper thumbnail of Adverse drug reactions reporting by undergraduate medical students in a tertiary care teaching hospital of India: Content and quality analysis in comparison to physician reporting

DOAJ (DOAJ: Directory of Open Access Journals), Aug 23, 2017

An important challenge to spontaneous reporting system is underreporting. The sensitization and i... more An important challenge to spontaneous reporting system is underreporting. The sensitization and involvement of undergraduate medical students can reduce underreporting in pharmacovigilance program. To analyze the clinical characteristics and reporting quality of adverse drug reactions (ADRs) by undergraduate medical students in comparison with physicians' reporting. We sensitized the second professional year undergraduate medical students about pharmacovigilance and asked them to submit reports of ADR observed during their clinical posting from January to December 2015. We compared students' reports with those sent by physicians (Department of Medicine and Allied Branches, Paediatric, Obstetrics and Gynaecology) of our institute during the same time period. We included ADRs of "certain," "probable," or "possible" categories as per the World Health Organization causality definitions in analysis of both groups. We excluded "unlikely," "unclassified," and "unclassifiable" causality ADRs from the analysis due to questionable association of reactions with suspected drugs. We collected data of demographics, pattern of ADRs, causative drugs, seriousness, other clinical characteristics, and quality of reporting. We analyzed a total number of 176 students' reports having 269 ADRs and 143 physicians' reports covering 180 ADRs. The students predominantly reported ADRs of single drug suspect (84.09% vs. 43.35%), "probable" causality (63.94% vs. 21.11), and augmented type reactions (67.29% vs. 55%) than physicians. Both groups did not differ in reporting of serious reactions (6.25% vs. 9.09%). Students most frequently suspected gastrointestinal disorders (35.68%), whereas physicians most frequently reported skin and appendages disorders (41.11%). Students and physicians more commonly suspected ADRs due to systemic anti-infective (33.64%) and nervous system (42.07%) class of drugs, respectively. The quality analysis suggested no substantial difference in most domains of ADR reporting among both groups. Students' reported valuable and clinically relevant ADRs. Medical students should be exposed to ADR reporting during their clinical teaching posting and should be actively involved in pharmacovigilance program to improve detection rate.

Research paper thumbnail of Adverse drug reactions reporting by undergraduate medical students in a tertiary care teaching hospital of India: Content and quality analysis in comparison to physician reporting

Perspectives in clinical research

An important challenge to spontaneous reporting system is underreporting. The sensitization and i... more An important challenge to spontaneous reporting system is underreporting. The sensitization and involvement of undergraduate medical students can reduce underreporting in pharmacovigilance program. To analyze the clinical characteristics and reporting quality of adverse drug reactions (ADRs) by undergraduate medical students in comparison with physicians' reporting. We sensitized the second professional year undergraduate medical students about pharmacovigilance and asked them to submit reports of ADR observed during their clinical posting from January to December 2015. We compared students' reports with those sent by physicians (Department of Medicine and Allied Branches, Paediatric, Obstetrics and Gynaecology) of our institute during the same time period. We included ADRs of "certain," "probable," or "possible" categories as per the World Health Organization causality definitions in analysis of both groups. We excluded "unlikely," &q...