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Research paper thumbnail of COVID-19 Pandemic: Implications for Oral Pathologists working in histopathology, cytology and hematology laboratories

IP Archives of Cytology and Histopathology Research

The personnel in histopathology, cytology and hematology laboratories are vulnerable to infection... more The personnel in histopathology, cytology and hematology laboratories are vulnerable to infection by tissue specimens and body fluids in the COVID-19 pandemic. This risk is essentially amplified for Oral Pathologists as they deal with tissues from oropharyngeal region which harbors high viral load. Thus, the pandemic has certain implications for modification in protocol to be followed in these laboratories. The present study gauges knowledge, attitude and awareness of Oral Pathologists with respect to these modifications required. Materials and Methods: A self-constructed e-questionnaire comprising of 22 questions was validated and then circulated online with the aid of messenger applications and e-mails to the eligible participants. All the respondents pursuing a post-graduation course or academic faculty in the subject of Oral Pathology were considered as eligible. The data was analyzed based on age, gender, qualification, affiliation and years of experience for the Oral Pathologist-based survey using Chi-Square test. Results: A relatively low knowledge was discerned amongst Oral Pathologists, regarding modifications required in various laboratory guidelines during the COVID-19 pandemic. Most of the respondents had a healthy attitude towards the preparedness and sustainability of their laboratory and its personnel. Conclusion: Adequate knowledge and training with regards to modifications in protocol in the wake of COVID-19 pandemic is essential for safeguarding Oral Pathologists working in histopathology, cytopathology and hematology laboratories. A healthy attitude of Oral Pathologists towards laboratory and its personnel would ensure a safe and efficient work environment.

Research paper thumbnail of Collagen – structure, function and distribution in orodental tissues

Journal of Global Oral Health

Collagens are a large family of triple helical proteins which are found extensively throughout th... more Collagens are a large family of triple helical proteins which are found extensively throughout the body. They form the basic framework of the extracellular matrix providing support and form to cells and tissues. They are important for various functions such as angiogenesis, morphogenesis, cell adhesion, repair, and regeneration. In this article, we have focused our discussion to the structure, the synthesis, and the degradation of collagen followed by its distribution and function in various oral tissues.

Research paper thumbnail of Collagen – structure, function and distribution in orodental tissues

Journal of Global Oral Health, Feb 29, 2020

Collagens are a large family of triple helical proteins which are found extensively throughout th... more Collagens are a large family of triple helical proteins which are found extensively throughout the body. They form the basic framework of the extracellular matrix providing support and form to cells and tissues. They are important for various functions such as angiogenesis, morphogenesis, cell adhesion, repair, and regeneration. In this article, we have focused our discussion to the structure, the synthesis, and the degradation of collagen followed by its distribution and function in various oral tissues.

Research paper thumbnail of Oral submucous fibrosis: Histopathological features with pathophysiologic correlations

IP Journal of Diagnostic Pathology and Oncology

Oral submucous fibrosis (OSMF) is a potentially malignant disorder characterized by juxtaepitheli... more Oral submucous fibrosis (OSMF) is a potentially malignant disorder characterized by juxtaepithelial inflammation and progressive fibrosis of submucosal tissues. It may affect any part of the oral cavity, as well as pharynx and oesophagus. The pathogenesis of OSMF may be attributable to habitual chewing of areca nut and its products, which is more prevalent amongst young population of South East Asia and India. Various histopathological features in different tissue components- epithelial, connective tissue stroma, muscle and salivary gland may be observed along the course of this chronic disorder. In connective tissue, extensive fibrosis with progressive hyalinization of collagen fibers and muscles accompanied by inflammatory response is considered to be pathognomonic feature. Advanced stages of OSMF may show atrophic changes or even dysplasia in the epithelium which may undergo malignant transformation. Malignant transformation rate of OSMF has been proved to be around 7.5%. Thus, i...

Research paper thumbnail of COVID-19 Pandemic: Implications for Oral Pathologists working in histopathology, cytology and hematology laboratories

IP Archives of Cytology and Histopathology Research

The personnel in histopathology, cytology and hematology laboratories are vulnerable to infection... more The personnel in histopathology, cytology and hematology laboratories are vulnerable to infection by tissue specimens and body fluids in the COVID-19 pandemic. This risk is essentially amplified for Oral Pathologists as they deal with tissues from oropharyngeal region which harbors high viral load. Thus, the pandemic has certain implications for modification in protocol to be followed in these laboratories. The present study gauges knowledge, attitude and awareness of Oral Pathologists with respect to these modifications required. Materials and Methods: A self-constructed e-questionnaire comprising of 22 questions was validated and then circulated online with the aid of messenger applications and e-mails to the eligible participants. All the respondents pursuing a post-graduation course or academic faculty in the subject of Oral Pathology were considered as eligible. The data was analyzed based on age, gender, qualification, affiliation and years of experience for the Oral Pathologist-based survey using Chi-Square test. Results: A relatively low knowledge was discerned amongst Oral Pathologists, regarding modifications required in various laboratory guidelines during the COVID-19 pandemic. Most of the respondents had a healthy attitude towards the preparedness and sustainability of their laboratory and its personnel. Conclusion: Adequate knowledge and training with regards to modifications in protocol in the wake of COVID-19 pandemic is essential for safeguarding Oral Pathologists working in histopathology, cytopathology and hematology laboratories. A healthy attitude of Oral Pathologists towards laboratory and its personnel would ensure a safe and efficient work environment.

Research paper thumbnail of Collagen – structure, function and distribution in orodental tissues

Journal of Global Oral Health

Collagens are a large family of triple helical proteins which are found extensively throughout th... more Collagens are a large family of triple helical proteins which are found extensively throughout the body. They form the basic framework of the extracellular matrix providing support and form to cells and tissues. They are important for various functions such as angiogenesis, morphogenesis, cell adhesion, repair, and regeneration. In this article, we have focused our discussion to the structure, the synthesis, and the degradation of collagen followed by its distribution and function in various oral tissues.

Research paper thumbnail of Collagen – structure, function and distribution in orodental tissues

Journal of Global Oral Health, Feb 29, 2020

Collagens are a large family of triple helical proteins which are found extensively throughout th... more Collagens are a large family of triple helical proteins which are found extensively throughout the body. They form the basic framework of the extracellular matrix providing support and form to cells and tissues. They are important for various functions such as angiogenesis, morphogenesis, cell adhesion, repair, and regeneration. In this article, we have focused our discussion to the structure, the synthesis, and the degradation of collagen followed by its distribution and function in various oral tissues.

Research paper thumbnail of Oral submucous fibrosis: Histopathological features with pathophysiologic correlations

IP Journal of Diagnostic Pathology and Oncology

Oral submucous fibrosis (OSMF) is a potentially malignant disorder characterized by juxtaepitheli... more Oral submucous fibrosis (OSMF) is a potentially malignant disorder characterized by juxtaepithelial inflammation and progressive fibrosis of submucosal tissues. It may affect any part of the oral cavity, as well as pharynx and oesophagus. The pathogenesis of OSMF may be attributable to habitual chewing of areca nut and its products, which is more prevalent amongst young population of South East Asia and India. Various histopathological features in different tissue components- epithelial, connective tissue stroma, muscle and salivary gland may be observed along the course of this chronic disorder. In connective tissue, extensive fibrosis with progressive hyalinization of collagen fibers and muscles accompanied by inflammatory response is considered to be pathognomonic feature. Advanced stages of OSMF may show atrophic changes or even dysplasia in the epithelium which may undergo malignant transformation. Malignant transformation rate of OSMF has been proved to be around 7.5%. Thus, i...