surbhi garg - Academia.edu (original) (raw)

Related Authors

zeinab kasemy

IOSR Journals

Amal Zaghloul

Alaa Ali

Murtaza Kamal

amna nasir

amna nasir

University of the Punjab, Lahore, Pakistan

Uploads

Papers by surbhi garg

Research paper thumbnail of Assessment of the prevalence of G6PD deficiency in RBCs of live new-borns born at tertiary care hospital

International Journal of Contemporary Pediatrics, 2019

Background: Glucose-6-phosphate dehydrogenase is one of many enzymes that help the body process c... more Background: Glucose-6-phosphate dehydrogenase is one of many enzymes that help the body process carbohydrates and turn them into energy. The mechanism by which G6PD deficiency causes neonatal hyper bilirubin may be due to hemolysis, but other mechanisms like secondary impairment of bilirubin conjugation and clearance by the liver may play a role. Therefore, through this study authors attempt to study the need for a newborn screening program for G6PD deficiency because of high prevalence and high risk of incidence due to consanguineous marriages in India.Methods: This study was a prospective cross-sectional study conducted among 350 consecutively born live new-borns in maternity wards and NICU of Krishna Institute of Medical Sciences and Hospital and Research Centre, Karad, Maharashtra during October 2016 to October 2017.Results: The maximum numbers of newborns were in the age group of 0-10 hours (36.80%), followed by in 11-20 hours (21.80%). The mean age among newborns was 2.86±5.83...

Research paper thumbnail of Pattern of serum protein capillary electrophoretogram in SARS- CoV-2 infection

Clinica Chimica Acta, 2022

Background and aims: Monoclonal/biclonalgammopathy of unknown significance (MGUS/BGUS) is observe... more Background and aims: Monoclonal/biclonalgammopathy of unknown significance (MGUS/BGUS) is observed in COVID-19. This study was conducted to determine the changes in serum protein electrophoresis (SPEP) in COVID-19. Materials and methods: In this descriptive (cross-sectional) study, serum inflammatory markers (CRP, IL-6 and ferritin) were measured and SPEP was carried out by capillary electrophoresis method in 35 controls and 30 moderate & 58 severe COVID-19 cases. Results: Serum inflammatory markers were increased in COVID-19 cases with severity. M− band(s), β-γ bridging and pre-albumin band(s) on SPEP were observed in 15.5, 11 & 12% of severe cases and 3, 4 & 0% moderate COVID-19 cases respectively. Area under curve (AUC) of α 1 and α 2 bands of SPEP increased significantly in severe COVID-19. Conclusions: We conclude that SPEP changes like the appearance of M− band(s) indicating MGUS(BGUS), β-γ bridging indicating the presence of fast-moving immunoglobulins, pre-albumin band indicating the rise in serum transthyretin level and the increase in AUC of α 1 and α 2 bands indicating the rise in positive acute phase reactants occur in COVID-19. The occurrence and magnitude of these changes are higher in severe COVID-19 than that in moderate COVID-19. The diagnostic and prognostic significance of these SPEP changes are worth exploring.

Research paper thumbnail of Investigation on potential of different bio-agents as soil application against root-knot nematode, Meloidogyne incognita infecting tomato

International Journal of Chemical Studies, 2020

Anexperiment trial was conducted during 2018-19 for the management of root-knot nematode, Meloido... more Anexperiment trial was conducted during 2018-19 for the management of root-knot nematode, Meloidogyne incognita through bio-agents as soil application on tomato in micro plots. M icro-plot was filled with root-knot nematode infested soil (520 IJs/100 cc soil) brought from the pure culture field. Bioagents viz., Purpureocillium lilacinum, Trichoderma harzianum and Pseudomonas fluorescens were added to soil @ 2.5 and 5.0 g per m 2. Standard check (Trichoderma viride @ 2.5 kg/ha) and control were also maintained for comparison. Results of bio-agent and dose interaction have indicated that P. lilacinum @ 5.0 g per m 2 was found best followed by P. fluorescens @ 5.0 g per m 2 and T. harzianum @ 5.0 g per m 2. However, T. viride 2.5 kg/ha was found superior in respect to plant yield and reducing nematode reproduction on tomato in comparison to all other treatments.

Research paper thumbnail of Assessment of the prevalence of G6PD deficiency in RBCs of live new-borns born at tertiary care hospital

International Journal of Contemporary Pediatrics, 2019

Background: Glucose-6-phosphate dehydrogenase is one of many enzymes that help the body process c... more Background: Glucose-6-phosphate dehydrogenase is one of many enzymes that help the body process carbohydrates and turn them into energy. The mechanism by which G6PD deficiency causes neonatal hyper bilirubin may be due to hemolysis, but other mechanisms like secondary impairment of bilirubin conjugation and clearance by the liver may play a role. Therefore, through this study authors attempt to study the need for a newborn screening program for G6PD deficiency because of high prevalence and high risk of incidence due to consanguineous marriages in India.Methods: This study was a prospective cross-sectional study conducted among 350 consecutively born live new-borns in maternity wards and NICU of Krishna Institute of Medical Sciences and Hospital and Research Centre, Karad, Maharashtra during October 2016 to October 2017.Results: The maximum numbers of newborns were in the age group of 0-10 hours (36.80%), followed by in 11-20 hours (21.80%). The mean age among newborns was 2.86±5.83...

Research paper thumbnail of Pattern of serum protein capillary electrophoretogram in SARS- CoV-2 infection

Clinica Chimica Acta, 2022

Background and aims: Monoclonal/biclonalgammopathy of unknown significance (MGUS/BGUS) is observe... more Background and aims: Monoclonal/biclonalgammopathy of unknown significance (MGUS/BGUS) is observed in COVID-19. This study was conducted to determine the changes in serum protein electrophoresis (SPEP) in COVID-19. Materials and methods: In this descriptive (cross-sectional) study, serum inflammatory markers (CRP, IL-6 and ferritin) were measured and SPEP was carried out by capillary electrophoresis method in 35 controls and 30 moderate & 58 severe COVID-19 cases. Results: Serum inflammatory markers were increased in COVID-19 cases with severity. M− band(s), β-γ bridging and pre-albumin band(s) on SPEP were observed in 15.5, 11 & 12% of severe cases and 3, 4 & 0% moderate COVID-19 cases respectively. Area under curve (AUC) of α 1 and α 2 bands of SPEP increased significantly in severe COVID-19. Conclusions: We conclude that SPEP changes like the appearance of M− band(s) indicating MGUS(BGUS), β-γ bridging indicating the presence of fast-moving immunoglobulins, pre-albumin band indicating the rise in serum transthyretin level and the increase in AUC of α 1 and α 2 bands indicating the rise in positive acute phase reactants occur in COVID-19. The occurrence and magnitude of these changes are higher in severe COVID-19 than that in moderate COVID-19. The diagnostic and prognostic significance of these SPEP changes are worth exploring.

Research paper thumbnail of Investigation on potential of different bio-agents as soil application against root-knot nematode, Meloidogyne incognita infecting tomato

International Journal of Chemical Studies, 2020

Anexperiment trial was conducted during 2018-19 for the management of root-knot nematode, Meloido... more Anexperiment trial was conducted during 2018-19 for the management of root-knot nematode, Meloidogyne incognita through bio-agents as soil application on tomato in micro plots. M icro-plot was filled with root-knot nematode infested soil (520 IJs/100 cc soil) brought from the pure culture field. Bioagents viz., Purpureocillium lilacinum, Trichoderma harzianum and Pseudomonas fluorescens were added to soil @ 2.5 and 5.0 g per m 2. Standard check (Trichoderma viride @ 2.5 kg/ha) and control were also maintained for comparison. Results of bio-agent and dose interaction have indicated that P. lilacinum @ 5.0 g per m 2 was found best followed by P. fluorescens @ 5.0 g per m 2 and T. harzianum @ 5.0 g per m 2. However, T. viride 2.5 kg/ha was found superior in respect to plant yield and reducing nematode reproduction on tomato in comparison to all other treatments.

Log In