tsung chen - Academia.edu (original) (raw)
Papers by tsung chen
2010 International Conference on Computational Intelligence and Software Engineering, 2010
Software validation is an attempt to ensure the product fulfills its specific intended purpose. S... more Software validation is an attempt to ensure the product fulfills its specific intended purpose. Software validation is very important since software is widely embedded in devices, and these devices are ubiquitous in our daily life nowadays. As software is getting more complex, the software validation process is getting more complicated and time consuming. The study of software validation is therefore an important active research field with voluminous publications. The sheer volume of software validation related literatures hinders our comprehending of its content and context. We therefore utilize the intellectual structure construction and knowledge domain visualization techniques developed by the information scientist to ease the task of understanding the main themes of this research domain. Base on the analysis, we can see the research themes of software validation may be divided into two main groups: the first one deals with systems with interweaving hardware and software related issues, such as real-time systems, parallel systems; the other one deals with model checking related issues, including automata theory and temporal logic.
African Journal of Business Management, Apr 30, 2010
The competition among hospitals in Taiwan has become more and more intense, especially since Nati... more The competition among hospitals in Taiwan has become more and more intense, especially since National Health Insurance has come into effect. The number of so-called "mega" hospitals is growing while the number of patients is limited. In this competitive environment, hospitals have to carry out their business not only by maintaining the balance between quality and cost, but also by increasing interaction with their customers (patients). Customer-oriented services are what will give hospitals their core competitive edge for sustainable development. The key to maintain good relationships with customers is based on analyzing data related to customer satisfaction, strengthening medical service quality and providing tailor-made service. By doing so, hospitals can develop a more valuable relationship with their customers. This study was conducted by questionnaire. The purpose is to examine the correlation between customer orientation, medical service quality, service value and patient satisfaction in relation to medical service providers located in southern Taiwan. The data were analyzed with statistical methods such as Pearson's correlation analysis, linear structure relation and analysis of variance. Our findings indicate that: (1) Customer orientation, medical service quality and value of patients are positively related to each other and patient satisfaction is influenced by these three constructs and; (2) There are significant differences shown by patients with different perceptions of customer orientation in relation to service quality and patient satisfaction constructs and so on, but no difference in relation to service constructs.
Communications in Computer and Information Science
ABSTRACT
BioMedicine, 2017
Most reports have indicated the antioxidant capacity of quinoa seeds. However, the leaves of Quin... more Most reports have indicated the antioxidant capacity of quinoa seeds. However, the leaves of Quinoa (Chenopodium quinoa Willd.) are usually worthless and little known about their biological activities. In this study, the antioxidant and immunomodulatory potential of the quinoa leaf extracts were explored. The crude leaf extracts of quinoa were extracted using water, 50% ethanol or 95% ethanol as solvent, denoted WQL, 50% EQL and 95% EQL, respectively. The antioxidant activities of quinoa leaf extracts were assessed by the ability of 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging and iron chelating. The total phenolic content was determined. Inhibition of nitric oxide (NO) production in the lipopolysaccharide (LPS)-induced murine macrophage RAW 264.7 cells was examined to gauge the anti-inflammatory activity. The 95% EQL showed a higher level of total phenolic content (569.5 mg GAE/g extract) and better DPPH scavenging activity. The WQL exhibited a better iron chelating capacity (28...
International journal of molecular medicine, Jan 30, 2018
Endoplasmic reticulum (ER) stress plays a vital role in mediating ischemic reperfusion damage in ... more Endoplasmic reticulum (ER) stress plays a vital role in mediating ischemic reperfusion damage in brain. In this study, we evaluated whether melatonin inhibits ER stress in cultured neurons exposed to oxygen and glucose deprivation (OGD) and in rats subjected to transient focal cerebral ischemia. Sprague-Dawley rats were treated with melatonin (5 mg/kg) or control at reperfusion onset after transient occlusion of the right middle cerebral artery (MCA) for 90 min. Brain infarction and hemorrhage within infarcts were measured. The expression of ER stress proteins of phosphorylation of PRKR‑like endoplasmic reticulum kinase (p-PERK), phosphorylation of eukaryotic translation initiation factor 2α (p-eIF2α), activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP) were detected by western blotting and immunohistochemistry analysis. The terminal deoxynucleotidyltransferase-mediated dUTP nick end labeling (TUNEL) method, cleaved caspase-3 and cytochrome c were used to in...
Journal of the Association for Information Science and Technology
ABSTRACT
Plant and Cell Physiology
... The system integrates data management, model management, and process management systems withi... more ... The system integrates data management, model management, and process management systems within a group decision support system environment. Knowledge management tools for describing, classifying, and storing the output of the planning process are described. ...
New Advances in Machine Learning, 2010
Due to the enormous amount of research publications are available, perceiving the growth of scien... more Due to the enormous amount of research publications are available, perceiving the growth of scientific knowledge even in one's own specialise field is a challenge task. It would be helpful if we could provide scientists with knowledge visualisation tools to discover the existence of a scientific paradigm and movements of such paradigms. This chapter introduces the state of the art of visualising knowledge structures. The aim of visualising knowledge structures is to capture intellectual structures of a particular knowledge domain. Approaches to the visualisation of knowledge structures with emphasis on the role of citation-based methods are described. The principal components of factor analysis and Pathfinder network are utilized to reveal new and signification developments of intellectual structure in ubiquitous computing research area. Literature published in the online citation data bases CiteSeer and Web of Science (WoS) are exploited to drive the main research themes and their interrelationships in ubiquitous computing. The benefit of the results obtained could be for someone new to a specific domain in research study, ubiquitous computing in this case. The outcome uncovers popular topics and important research in the particular domain. Potential developments can be re-used and utilized in other disciplines and share across different research domains.
Key Engineering Materials, Jan 6, 2015
This study is focused on the influences of micro stretching process, miniaturized of micro square... more This study is focused on the influences of micro stretching process, miniaturized of micro square hole-flange to stainless steel (SUS304) material, and different thicknesses (0.2, 0.1, 0.05mm) of plate. By undergoing finite element program analysis of material parameter corrected by scale factor, we can discover the differences of different thicknesses of plate during micro stretching forming process. The finite element method in this paper is combined with the plastic flow rule of Dynaform and LS-DYNA solver, finite element deformed theory, and updated Lagrangian formulation to simulate the process of micro square hole-flange. The point of this research is by simulating and analyzing all datum of micro stretching forming process, relation between punch load and stroke, distribution of thickness, distribution of stress and strain, the maximum diameter of flange’s hole and the maximum height of flange. Design three pairs of micro square hole-flange tool undergoing micro stretching experience through SUS304 plate. Compare the experience to the results of the simulation to test the reliability of this analyzing program. Through finite element analysis and the results of the experience, we can discover that the minimum of the thickness, the biggest stress and major strain centralize areas where blank and punch corner meet.
Key Engineering Materials, Jun 6, 2007
This study aims to clarify the process conditions of the UO-tube of a sheet metal of steel. It pr... more This study aims to clarify the process conditions of the UO-tube of a sheet metal of steel. It provides a model that predicts not only the correct punch load for drawing, but also the precise final shape of products after unloading, based on the tensile properties of the material and the geometry of the tools used. An elasto-plastic incremental finite-element computer code, based on an updated Lagrangian formulation, was developed to simulate the UO-tube process of sheet metal; the results are compared with corresponding experimental results. Special care was taken to formulate accurate boundary conditions of penetration, separation and alternation of the sliding-sticking state of friction, as the contact conditions between the tools and the sheet varied throughout the entire processes of U-bending and successive O-bending. Calculated sheet geometries and forming force agree well with experimental data. In particular, selective reduced integration was adopted to formulate the stiffness matrix. The extended r-minimum technique was used to deal with the elasto-plastic state and contact problems at the tool-metal interface. A series of simulations were performed to validate the formulation in the theory, leading to the development of the computer codes. The whole deformation history, the distribution of stress and the distribution of strain during the forming process were obtained by carefully considering the moving boundary condition in the finite-element method. The simulation demonstrates clearly the efficiency of the code to simulate various bending processes that proceed under complicated deformation- and contact-history.
Materials Science Forum, 2006
2010 International Conference on Computational Intelligence and Software Engineering, 2010
Software validation is an attempt to ensure the product fulfills its specific intended purpose. S... more Software validation is an attempt to ensure the product fulfills its specific intended purpose. Software validation is very important since software is widely embedded in devices, and these devices are ubiquitous in our daily life nowadays. As software is getting more complex, the software validation process is getting more complicated and time consuming. The study of software validation is therefore an important active research field with voluminous publications. The sheer volume of software validation related literatures hinders our comprehending of its content and context. We therefore utilize the intellectual structure construction and knowledge domain visualization techniques developed by the information scientist to ease the task of understanding the main themes of this research domain. Base on the analysis, we can see the research themes of software validation may be divided into two main groups: the first one deals with systems with interweaving hardware and software related issues, such as real-time systems, parallel systems; the other one deals with model checking related issues, including automata theory and temporal logic.
African Journal of Business Management, Apr 30, 2010
The competition among hospitals in Taiwan has become more and more intense, especially since Nati... more The competition among hospitals in Taiwan has become more and more intense, especially since National Health Insurance has come into effect. The number of so-called "mega" hospitals is growing while the number of patients is limited. In this competitive environment, hospitals have to carry out their business not only by maintaining the balance between quality and cost, but also by increasing interaction with their customers (patients). Customer-oriented services are what will give hospitals their core competitive edge for sustainable development. The key to maintain good relationships with customers is based on analyzing data related to customer satisfaction, strengthening medical service quality and providing tailor-made service. By doing so, hospitals can develop a more valuable relationship with their customers. This study was conducted by questionnaire. The purpose is to examine the correlation between customer orientation, medical service quality, service value and patient satisfaction in relation to medical service providers located in southern Taiwan. The data were analyzed with statistical methods such as Pearson's correlation analysis, linear structure relation and analysis of variance. Our findings indicate that: (1) Customer orientation, medical service quality and value of patients are positively related to each other and patient satisfaction is influenced by these three constructs and; (2) There are significant differences shown by patients with different perceptions of customer orientation in relation to service quality and patient satisfaction constructs and so on, but no difference in relation to service constructs.
Communications in Computer and Information Science
ABSTRACT
BioMedicine, 2017
Most reports have indicated the antioxidant capacity of quinoa seeds. However, the leaves of Quin... more Most reports have indicated the antioxidant capacity of quinoa seeds. However, the leaves of Quinoa (Chenopodium quinoa Willd.) are usually worthless and little known about their biological activities. In this study, the antioxidant and immunomodulatory potential of the quinoa leaf extracts were explored. The crude leaf extracts of quinoa were extracted using water, 50% ethanol or 95% ethanol as solvent, denoted WQL, 50% EQL and 95% EQL, respectively. The antioxidant activities of quinoa leaf extracts were assessed by the ability of 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging and iron chelating. The total phenolic content was determined. Inhibition of nitric oxide (NO) production in the lipopolysaccharide (LPS)-induced murine macrophage RAW 264.7 cells was examined to gauge the anti-inflammatory activity. The 95% EQL showed a higher level of total phenolic content (569.5 mg GAE/g extract) and better DPPH scavenging activity. The WQL exhibited a better iron chelating capacity (28...
International journal of molecular medicine, Jan 30, 2018
Endoplasmic reticulum (ER) stress plays a vital role in mediating ischemic reperfusion damage in ... more Endoplasmic reticulum (ER) stress plays a vital role in mediating ischemic reperfusion damage in brain. In this study, we evaluated whether melatonin inhibits ER stress in cultured neurons exposed to oxygen and glucose deprivation (OGD) and in rats subjected to transient focal cerebral ischemia. Sprague-Dawley rats were treated with melatonin (5 mg/kg) or control at reperfusion onset after transient occlusion of the right middle cerebral artery (MCA) for 90 min. Brain infarction and hemorrhage within infarcts were measured. The expression of ER stress proteins of phosphorylation of PRKR‑like endoplasmic reticulum kinase (p-PERK), phosphorylation of eukaryotic translation initiation factor 2α (p-eIF2α), activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP) were detected by western blotting and immunohistochemistry analysis. The terminal deoxynucleotidyltransferase-mediated dUTP nick end labeling (TUNEL) method, cleaved caspase-3 and cytochrome c were used to in...
Journal of the Association for Information Science and Technology
ABSTRACT
Plant and Cell Physiology
... The system integrates data management, model management, and process management systems withi... more ... The system integrates data management, model management, and process management systems within a group decision support system environment. Knowledge management tools for describing, classifying, and storing the output of the planning process are described. ...
New Advances in Machine Learning, 2010
Due to the enormous amount of research publications are available, perceiving the growth of scien... more Due to the enormous amount of research publications are available, perceiving the growth of scientific knowledge even in one's own specialise field is a challenge task. It would be helpful if we could provide scientists with knowledge visualisation tools to discover the existence of a scientific paradigm and movements of such paradigms. This chapter introduces the state of the art of visualising knowledge structures. The aim of visualising knowledge structures is to capture intellectual structures of a particular knowledge domain. Approaches to the visualisation of knowledge structures with emphasis on the role of citation-based methods are described. The principal components of factor analysis and Pathfinder network are utilized to reveal new and signification developments of intellectual structure in ubiquitous computing research area. Literature published in the online citation data bases CiteSeer and Web of Science (WoS) are exploited to drive the main research themes and their interrelationships in ubiquitous computing. The benefit of the results obtained could be for someone new to a specific domain in research study, ubiquitous computing in this case. The outcome uncovers popular topics and important research in the particular domain. Potential developments can be re-used and utilized in other disciplines and share across different research domains.
Key Engineering Materials, Jan 6, 2015
This study is focused on the influences of micro stretching process, miniaturized of micro square... more This study is focused on the influences of micro stretching process, miniaturized of micro square hole-flange to stainless steel (SUS304) material, and different thicknesses (0.2, 0.1, 0.05mm) of plate. By undergoing finite element program analysis of material parameter corrected by scale factor, we can discover the differences of different thicknesses of plate during micro stretching forming process. The finite element method in this paper is combined with the plastic flow rule of Dynaform and LS-DYNA solver, finite element deformed theory, and updated Lagrangian formulation to simulate the process of micro square hole-flange. The point of this research is by simulating and analyzing all datum of micro stretching forming process, relation between punch load and stroke, distribution of thickness, distribution of stress and strain, the maximum diameter of flange’s hole and the maximum height of flange. Design three pairs of micro square hole-flange tool undergoing micro stretching experience through SUS304 plate. Compare the experience to the results of the simulation to test the reliability of this analyzing program. Through finite element analysis and the results of the experience, we can discover that the minimum of the thickness, the biggest stress and major strain centralize areas where blank and punch corner meet.
Key Engineering Materials, Jun 6, 2007
This study aims to clarify the process conditions of the UO-tube of a sheet metal of steel. It pr... more This study aims to clarify the process conditions of the UO-tube of a sheet metal of steel. It provides a model that predicts not only the correct punch load for drawing, but also the precise final shape of products after unloading, based on the tensile properties of the material and the geometry of the tools used. An elasto-plastic incremental finite-element computer code, based on an updated Lagrangian formulation, was developed to simulate the UO-tube process of sheet metal; the results are compared with corresponding experimental results. Special care was taken to formulate accurate boundary conditions of penetration, separation and alternation of the sliding-sticking state of friction, as the contact conditions between the tools and the sheet varied throughout the entire processes of U-bending and successive O-bending. Calculated sheet geometries and forming force agree well with experimental data. In particular, selective reduced integration was adopted to formulate the stiffness matrix. The extended r-minimum technique was used to deal with the elasto-plastic state and contact problems at the tool-metal interface. A series of simulations were performed to validate the formulation in the theory, leading to the development of the computer codes. The whole deformation history, the distribution of stress and the distribution of strain during the forming process were obtained by carefully considering the moving boundary condition in the finite-element method. The simulation demonstrates clearly the efficiency of the code to simulate various bending processes that proceed under complicated deformation- and contact-history.
Materials Science Forum, 2006