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Papers by tugba unver
Selcuk dental journal, Nov 11, 2019
Dental Volumetrik Tomografi (DVT), Bilgisayarlı Tomografi (BT) ile karşılaştırıldığında belirgin ... more Dental Volumetrik Tomografi (DVT), Bilgisayarlı Tomografi (BT) ile karşılaştırıldığında belirgin derecede daha düşük radyasyon verdiği için diş hekimliğinde daha çok tercih edilen bir teşhis aracıdır. 1,2 "Düşük radyasyon" ifadesi dikkatli yorumlanmalıdır. Çünkü güvenli olarak kabul edilen radyasyon miktarını tanımlamak için düşük doz eşiği yoktur. Radyasyon dozunun yanı sıra, görüntüde oluşan artefakt varlığı DVT'nin en önemli dezavantajlarından biridir. Uzun tarama süresi kafa hareketine neden olduğu için artefakt riskini de arttırmaktadır. 4 Hareket artefaktları görüntü kalitesinin bozulmasına yol açarak radyografi çekiminin tekrarlanmasına neden olabilmektedir. 5,6 Bu, DVT çekilen hasta için önemli bir noktadır, çünkü çekimi tekrarlamak gerektiğinde hasta gereksiz yere X-ışınına maruz kalacaktır. 1
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Selcuk dental journal, Nov 11, 2019
Journal of stomatology, oral and maxillofacial surgery, 2020
OBJECTIVE Hypercalcemia is determined as an increase in the serum calcium level (above 10.5 mg/dL... more OBJECTIVE Hypercalcemia is determined as an increase in the serum calcium level (above 10.5 mg/dL or ionized calcium is above 1.5 mmol/L). It was aimed to evaluate the effect of the increased serum calcium levels in dental panoramic radiographs with oral pathologies. MATERIALS & METHODS The final sample number of the present study was determined as 143. 61 patients with hypercalcemic calcium levels were grouped in Hypercalcemia Group (HPEG) whereas 82 patients were grouped in Normal Group. (NG) Measurements were performed only on the panoramic radiographs. The evaluated parameters were cyst-tumor or granuloma existence, sinus pneumatization, stylohyoid ligament calcifications, lamina dura loss, bone loss existence, etc. Statistical tests were carried out at p < 0.05 significance level. RESULTS The cyst-tumor formation (p = 0.03) and stylohyoid ligament calcification (p = 0.009) and increased radiopacity (p = 0.03) were significantly more common in NG than the HPEG group. Alveolar...
British Journal of Oral and Maxillofacial Surgery, 2019
SDÜ Tıp Fakültesi Dergisi, 2019
Amac: Bu calismanin amaci, enjekte edilebilen trombositten zengin fibrin'nin (i-PRF) eroziv ... more Amac: Bu calismanin amaci, enjekte edilebilen trombositten zengin fibrin'nin (i-PRF) eroziv liken planus (EOLP) lezyonlari uzerindeki klinik etkisini degerlendirmek ve kortikosteroid tedavisi ile karsilastirmaktir. Gerec ve Yontem: Yanak mukozasinda cift tarafli EOLP bulunan 13 sistemik saglikli hastanin yanak mukozalarinin bir tarafina i-PRF, diger tarafina intralezyonel kortikosteroid enjeksiyonu yapilmistir. Enjeksiyonlar 15 gun araya 4 seans tekrarlanmistir. Subjektif degerlendirme belirteci olarak gorsel analog skala (VAS), objektif degerlendirme belirteci olarak Thongprasom skorlari kullanilmistir. Skorlamalar tedaviden once, son enjeksiyon seansindan hemen sonra, tedavi sonrasi 1. ay ve tedavi sonrasi 2. ay kontrol seanslarinda yapilmistir. Bulgular: Gruplar arasi karsilastirmada, baslangic ve kontrol seanslarinda VAS-Agri , VAS-Memnuniyet ve Thongprasom skorlarinda istatistiksel olarak anlamli bir fark bulunamamistir. Grup ici karsilastirmalarda hem i-PRF uygulanan grupta (VAS-Agri 83,46 ± 16,25'ten 7,69 ± 9,92'ye dustu (p <0,001), VAS-Memnuniyet 26,54 ± 19,73'ten 87,31 ± 9,71'e yukseldi (p <0,001), Thongprasom skorlari 4,85 ± 0,37'den 2,08 ± 1,04'e dustu (p = 0,001)), hem de kortikosteroid uygulanan grupta (VAS-Agri 83,46 ± 16,25'ten 10,77 ± 14,27'ye dustu (p <0,001), VAS-Memnuniyet 26,54 ± 19,72'den 84,23 ± 13,52'ye yukseldi (p <0,001), Thongprasom skorlari 4,54 ± 0,52'den 2,00 ± 1,22’e dustu (p = 0,001)) VAS-Agri ve Thongprasom skorlarinin ortalama degerlerinde istatistiksel olarak anlamli bir dusus gorulurken, VAS-Memnuniyet skorlarinin ortalamasinda istatistiksel olarak anlamli bir artis gozlenmistir. Sonuc: Bu pilot calisma, i-PRF enjeksiyonunun EOLP lezyonlarin tedavisinde altin standart kabul edilen kortikosteroid enjeksiyonuna benzer derecede etkili olabilecegini gostermistir.
Annals of Medical Research, 2019
The aim of the present study was to analyze the comparative effectiveness of the diode lasers hav... more The aim of the present study was to analyze the comparative effectiveness of the diode lasers having 3 different wavelengths (810nm, 940nm, 980nm) and also the different application modes on the cellular basis in animal models.Many surgical instruments like scalpel, electrosurgery, and different laser types can be used for surgical incisions. Each of these have their own advantages and disadvantages. Material and Methods: 10 mm in length and 1 mm in depth dorsal skin incisions were created on 18 male Wistar albino rats via 3 different laser wavelengths: 810nm (Gigaa, Cheese, China), 940nm(Epic 10, Biolase, USA) and 980nm (SIROlaser Advance, Sirona, Bensheim, Germany). The animals were sacrificed at either post-operative 24 hours, 3 days or 1 week. All incision sites were removed by excisional biopsies and the samples underwent histopathological evaluation. Results: There were no statistically significant differences in thermal changes, inflammation, and fibrosis in all wavelength groups (p>0.05). The chopped mode of irradiation of all wavelengths showed significant increase in epithelial closure following the operation (p<0.05). There were significant increases of the granulation tissue formation on the 3rd post-operative day with 940nm using chopped mode and 810nm in continuous mode (p<0.05). Conclusion: Pulsed mode of lasers accelerates the epithelization regardless of the wavelengths while 940nm and 810nm lasers in continuous mode speeds up the granulation tissue formation.
Objective: The aim of this study is to assess the effects of laser irradiation with a novel snori... more Objective: The aim of this study is to assess the effects of laser irradiation with a novel snoring handpiece on the histological structures of the soft palate in a rat model. Background: Snoring is a common problem in adults that affects between 20–50% of the population. The sound of snoring is usually a consequence of the vibration of pharyngeal soft tissue, and treatment aims to reduce these vibrations. There are many types of surgical treatment procedures that have been defined up until now, and among the treatment options, the main goal is to find a simple, safe and effective method. Methods: Twenty adult Wistar albino rats weighing 200 to 250 g were used in this study. Rats were randomized into two groups as an experimental (n=10) and a control group (n=10). Laser energy was delivered in a horizontal direction to the surface of the soft palate of each rat in the experimental group for 2 minutes with an Er:YAG laser (LightWalker AT, Fotona, Slovenia) with a snoring handpiece (P...
Journal of Applied Oral Science, 2021
Efficacy of injectable platelet-rich fibrin in the erosive oral lichen planus: a split-mouth, ran... more Efficacy of injectable platelet-rich fibrin in the erosive oral lichen planus: a split-mouth, randomized, controlled clinical trial* Objective: Our study compared the effects of injectable platelet-rich fibrin (i-PRF) with those of corticosteroids in the treatment of erosive oral lichen planus (EOLP). Methodology: This split-mouth study included 24 individuals diagnosed histopathologically with bilateral EOLP. One bilateral lesion was injected with i-PRF, whereas the other was injected with methylprednisolone acetate in four sessions at 15-day intervals. Visual analog scale (VAS) for pain and satisfaction, oral health impact profile scale-14, and the lesion size were used. Results: The intragroup comparisons showed a significant decrease in VAS-pain and lesion size in both the i-PRF group (from 81.88±17.74 to 13.33±18.34, and from 4.79±0.41 to 1.88±1.08, respectively) and the corticosteroid group (from 80.21±17.35 to 23.33±26.81, and from 4.71±0.46 to 2.21±1.35, respectively) in the 6th month compared to baseline (p<0.001). Moreover, VAS-satisfaction increased significantly in both the i-PRF group (from 26.67±17.8 to 85.63±16.24) and the corticosteroid group (from 28.33±17.05 to 74.38±24.11) in the 6th month compared to baseline (p<0.001). However, no significant difference in any value occurred in the intergroup comparisons. Conclusion: In patients with EOLP, both methods decreased pain and lesion size similarly, and both increased satisfaction. Therefore, the use of i-PRF may be considered an option in cases refractory to topical corticosteroid therapy. Biochemical and histopathological studies are required to reveal the mechanism of i-PRF action in EOLP treatment.
Background Perception of pain associated with intraoral radiography in pediatric patients was eva... more Background Perception of pain associated with intraoral radiography in pediatric patients was evaluated through statistical comparisons of data obtained using the Wong-Baker FACES Pain Raiting Scale (WBFPRS) and visual analog scale (VAS) scoring. Methods A total of 75 pediatric patients aged 6–12 years were included in this study. Simulations of each of three radiological methods (analog films, CCD sensor and phosphorus plates) were performed on 25 pediatric patients. Following the simulations, the meaning of each facial expression on the WBFPRS and the numbers on the VAS were explained to each child. For the comparison between groups, the homogeneity of the variances was tested with Levene’s test; because the variances were not homogeneous, Welch’s test was used. Tamhane’s T2 test was used because the homogeneity assumption was not provided to determine the source of the difference between the groups. Results When the conventional method was compared to the PSPL (photostimulable ph...
Photomedicine and laser surgery, 2016
The aim of this study was to assess the effects of laser irradiation with a novel snoring handpie... more The aim of this study was to assess the effects of laser irradiation with a novel snoring handpiece on the histological structures of the soft palate in a rat model. Snoring is a common problem and studies have shown that 20-50% of the population is affected. An apnea-hypopnea index of <5/h without daytime somnolence is documented as simple snoring. No snoring treatment should ever be attempted until a sleep study has been completed to rule out sleep apnea. Twenty adult Wistar rats, weighing 200-250 g, were used in this study. Rats were randomized into two groups: experimental group (n = 10) and control group (n = 10). Laser energy was delivered in a horizontal direction to the surface of the soft palate of each rat in the experimental group for 2 min with an Er:YAG laser (LightWalker AT; Fotona) with snoring handpiece (PS04) in a noncontact mode (1.15 W, 2 Hz, 1.5 J/cm(2)). The animals were sacrificed after 24 h, 1 week, 3 weeks, or 5 weeks. The soft palate of each rat was remov...
Selcuk dental journal, Nov 11, 2019
Dental Volumetrik Tomografi (DVT), Bilgisayarlı Tomografi (BT) ile karşılaştırıldığında belirgin ... more Dental Volumetrik Tomografi (DVT), Bilgisayarlı Tomografi (BT) ile karşılaştırıldığında belirgin derecede daha düşük radyasyon verdiği için diş hekimliğinde daha çok tercih edilen bir teşhis aracıdır. 1,2 "Düşük radyasyon" ifadesi dikkatli yorumlanmalıdır. Çünkü güvenli olarak kabul edilen radyasyon miktarını tanımlamak için düşük doz eşiği yoktur. Radyasyon dozunun yanı sıra, görüntüde oluşan artefakt varlığı DVT'nin en önemli dezavantajlarından biridir. Uzun tarama süresi kafa hareketine neden olduğu için artefakt riskini de arttırmaktadır. 4 Hareket artefaktları görüntü kalitesinin bozulmasına yol açarak radyografi çekiminin tekrarlanmasına neden olabilmektedir. 5,6 Bu, DVT çekilen hasta için önemli bir noktadır, çünkü çekimi tekrarlamak gerektiğinde hasta gereksiz yere X-ışınına maruz kalacaktır. 1
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Selcuk dental journal, Nov 11, 2019
Journal of stomatology, oral and maxillofacial surgery, 2020
OBJECTIVE Hypercalcemia is determined as an increase in the serum calcium level (above 10.5 mg/dL... more OBJECTIVE Hypercalcemia is determined as an increase in the serum calcium level (above 10.5 mg/dL or ionized calcium is above 1.5 mmol/L). It was aimed to evaluate the effect of the increased serum calcium levels in dental panoramic radiographs with oral pathologies. MATERIALS & METHODS The final sample number of the present study was determined as 143. 61 patients with hypercalcemic calcium levels were grouped in Hypercalcemia Group (HPEG) whereas 82 patients were grouped in Normal Group. (NG) Measurements were performed only on the panoramic radiographs. The evaluated parameters were cyst-tumor or granuloma existence, sinus pneumatization, stylohyoid ligament calcifications, lamina dura loss, bone loss existence, etc. Statistical tests were carried out at p < 0.05 significance level. RESULTS The cyst-tumor formation (p = 0.03) and stylohyoid ligament calcification (p = 0.009) and increased radiopacity (p = 0.03) were significantly more common in NG than the HPEG group. Alveolar...
British Journal of Oral and Maxillofacial Surgery, 2019
SDÜ Tıp Fakültesi Dergisi, 2019
Amac: Bu calismanin amaci, enjekte edilebilen trombositten zengin fibrin'nin (i-PRF) eroziv ... more Amac: Bu calismanin amaci, enjekte edilebilen trombositten zengin fibrin'nin (i-PRF) eroziv liken planus (EOLP) lezyonlari uzerindeki klinik etkisini degerlendirmek ve kortikosteroid tedavisi ile karsilastirmaktir. Gerec ve Yontem: Yanak mukozasinda cift tarafli EOLP bulunan 13 sistemik saglikli hastanin yanak mukozalarinin bir tarafina i-PRF, diger tarafina intralezyonel kortikosteroid enjeksiyonu yapilmistir. Enjeksiyonlar 15 gun araya 4 seans tekrarlanmistir. Subjektif degerlendirme belirteci olarak gorsel analog skala (VAS), objektif degerlendirme belirteci olarak Thongprasom skorlari kullanilmistir. Skorlamalar tedaviden once, son enjeksiyon seansindan hemen sonra, tedavi sonrasi 1. ay ve tedavi sonrasi 2. ay kontrol seanslarinda yapilmistir. Bulgular: Gruplar arasi karsilastirmada, baslangic ve kontrol seanslarinda VAS-Agri , VAS-Memnuniyet ve Thongprasom skorlarinda istatistiksel olarak anlamli bir fark bulunamamistir. Grup ici karsilastirmalarda hem i-PRF uygulanan grupta (VAS-Agri 83,46 ± 16,25'ten 7,69 ± 9,92'ye dustu (p <0,001), VAS-Memnuniyet 26,54 ± 19,73'ten 87,31 ± 9,71'e yukseldi (p <0,001), Thongprasom skorlari 4,85 ± 0,37'den 2,08 ± 1,04'e dustu (p = 0,001)), hem de kortikosteroid uygulanan grupta (VAS-Agri 83,46 ± 16,25'ten 10,77 ± 14,27'ye dustu (p <0,001), VAS-Memnuniyet 26,54 ± 19,72'den 84,23 ± 13,52'ye yukseldi (p <0,001), Thongprasom skorlari 4,54 ± 0,52'den 2,00 ± 1,22’e dustu (p = 0,001)) VAS-Agri ve Thongprasom skorlarinin ortalama degerlerinde istatistiksel olarak anlamli bir dusus gorulurken, VAS-Memnuniyet skorlarinin ortalamasinda istatistiksel olarak anlamli bir artis gozlenmistir. Sonuc: Bu pilot calisma, i-PRF enjeksiyonunun EOLP lezyonlarin tedavisinde altin standart kabul edilen kortikosteroid enjeksiyonuna benzer derecede etkili olabilecegini gostermistir.
Annals of Medical Research, 2019
The aim of the present study was to analyze the comparative effectiveness of the diode lasers hav... more The aim of the present study was to analyze the comparative effectiveness of the diode lasers having 3 different wavelengths (810nm, 940nm, 980nm) and also the different application modes on the cellular basis in animal models.Many surgical instruments like scalpel, electrosurgery, and different laser types can be used for surgical incisions. Each of these have their own advantages and disadvantages. Material and Methods: 10 mm in length and 1 mm in depth dorsal skin incisions were created on 18 male Wistar albino rats via 3 different laser wavelengths: 810nm (Gigaa, Cheese, China), 940nm(Epic 10, Biolase, USA) and 980nm (SIROlaser Advance, Sirona, Bensheim, Germany). The animals were sacrificed at either post-operative 24 hours, 3 days or 1 week. All incision sites were removed by excisional biopsies and the samples underwent histopathological evaluation. Results: There were no statistically significant differences in thermal changes, inflammation, and fibrosis in all wavelength groups (p>0.05). The chopped mode of irradiation of all wavelengths showed significant increase in epithelial closure following the operation (p<0.05). There were significant increases of the granulation tissue formation on the 3rd post-operative day with 940nm using chopped mode and 810nm in continuous mode (p<0.05). Conclusion: Pulsed mode of lasers accelerates the epithelization regardless of the wavelengths while 940nm and 810nm lasers in continuous mode speeds up the granulation tissue formation.
Objective: The aim of this study is to assess the effects of laser irradiation with a novel snori... more Objective: The aim of this study is to assess the effects of laser irradiation with a novel snoring handpiece on the histological structures of the soft palate in a rat model. Background: Snoring is a common problem in adults that affects between 20–50% of the population. The sound of snoring is usually a consequence of the vibration of pharyngeal soft tissue, and treatment aims to reduce these vibrations. There are many types of surgical treatment procedures that have been defined up until now, and among the treatment options, the main goal is to find a simple, safe and effective method. Methods: Twenty adult Wistar albino rats weighing 200 to 250 g were used in this study. Rats were randomized into two groups as an experimental (n=10) and a control group (n=10). Laser energy was delivered in a horizontal direction to the surface of the soft palate of each rat in the experimental group for 2 minutes with an Er:YAG laser (LightWalker AT, Fotona, Slovenia) with a snoring handpiece (P...
Journal of Applied Oral Science, 2021
Efficacy of injectable platelet-rich fibrin in the erosive oral lichen planus: a split-mouth, ran... more Efficacy of injectable platelet-rich fibrin in the erosive oral lichen planus: a split-mouth, randomized, controlled clinical trial* Objective: Our study compared the effects of injectable platelet-rich fibrin (i-PRF) with those of corticosteroids in the treatment of erosive oral lichen planus (EOLP). Methodology: This split-mouth study included 24 individuals diagnosed histopathologically with bilateral EOLP. One bilateral lesion was injected with i-PRF, whereas the other was injected with methylprednisolone acetate in four sessions at 15-day intervals. Visual analog scale (VAS) for pain and satisfaction, oral health impact profile scale-14, and the lesion size were used. Results: The intragroup comparisons showed a significant decrease in VAS-pain and lesion size in both the i-PRF group (from 81.88±17.74 to 13.33±18.34, and from 4.79±0.41 to 1.88±1.08, respectively) and the corticosteroid group (from 80.21±17.35 to 23.33±26.81, and from 4.71±0.46 to 2.21±1.35, respectively) in the 6th month compared to baseline (p<0.001). Moreover, VAS-satisfaction increased significantly in both the i-PRF group (from 26.67±17.8 to 85.63±16.24) and the corticosteroid group (from 28.33±17.05 to 74.38±24.11) in the 6th month compared to baseline (p<0.001). However, no significant difference in any value occurred in the intergroup comparisons. Conclusion: In patients with EOLP, both methods decreased pain and lesion size similarly, and both increased satisfaction. Therefore, the use of i-PRF may be considered an option in cases refractory to topical corticosteroid therapy. Biochemical and histopathological studies are required to reveal the mechanism of i-PRF action in EOLP treatment.
Background Perception of pain associated with intraoral radiography in pediatric patients was eva... more Background Perception of pain associated with intraoral radiography in pediatric patients was evaluated through statistical comparisons of data obtained using the Wong-Baker FACES Pain Raiting Scale (WBFPRS) and visual analog scale (VAS) scoring. Methods A total of 75 pediatric patients aged 6–12 years were included in this study. Simulations of each of three radiological methods (analog films, CCD sensor and phosphorus plates) were performed on 25 pediatric patients. Following the simulations, the meaning of each facial expression on the WBFPRS and the numbers on the VAS were explained to each child. For the comparison between groups, the homogeneity of the variances was tested with Levene’s test; because the variances were not homogeneous, Welch’s test was used. Tamhane’s T2 test was used because the homogeneity assumption was not provided to determine the source of the difference between the groups. Results When the conventional method was compared to the PSPL (photostimulable ph...
Photomedicine and laser surgery, 2016
The aim of this study was to assess the effects of laser irradiation with a novel snoring handpie... more The aim of this study was to assess the effects of laser irradiation with a novel snoring handpiece on the histological structures of the soft palate in a rat model. Snoring is a common problem and studies have shown that 20-50% of the population is affected. An apnea-hypopnea index of <5/h without daytime somnolence is documented as simple snoring. No snoring treatment should ever be attempted until a sleep study has been completed to rule out sleep apnea. Twenty adult Wistar rats, weighing 200-250 g, were used in this study. Rats were randomized into two groups: experimental group (n = 10) and control group (n = 10). Laser energy was delivered in a horizontal direction to the surface of the soft palate of each rat in the experimental group for 2 min with an Er:YAG laser (LightWalker AT; Fotona) with snoring handpiece (PS04) in a noncontact mode (1.15 W, 2 Hz, 1.5 J/cm(2)). The animals were sacrificed after 24 h, 1 week, 3 weeks, or 5 weeks. The soft palate of each rat was remov...