urmila jhamb - Academia.edu (original) (raw)
Papers by urmila jhamb
Pediatric Respirology and Critical Care Medicine
Jaypee Brothers Medical Publishers (P) Ltd. eBooks, 2004
Clinical Gastroenterology and Hepatology, Jul 1, 2015
establishing the severity. Periods of hypopnea associated with hypercarbia are the usual findings... more establishing the severity. Periods of hypopnea associated with hypercarbia are the usual findings on sleep studies. Treatment of choice is surgery, which was curative in our case too? Studies decumenting the efficacy of Fluticasone nasal spray for OSA in children due to adenoidotonsilar hypertrophy, have appeared in literature and seem to be encouraging?
DOAJ (DOAJ: Directory of Open Access Journals), 2022
Jaypee Brothers Medical Publishers (P) Ltd. eBooks, 2011
Pediatric Critical Care Medicine, 2018
Journal of Tropical Pediatrics, Jun 6, 2022
Background: Coronavirus disease 2019 (COVID-19) has had devastating effects on the health of mill... more Background: Coronavirus disease 2019 (COVID-19) has had devastating effects on the health of millions globally. Patients with tuberculosis (TB) are a vulnerable population. There is paucity of data to assess association between the 2 diseases in Pediatric population. Objective: To elucidate the effect of concomitant TB on clinical course of pediatric COVID-19 disease. Methods: Retrospective matched cohort study was conducted at dedicated tertiary COVID-19 hospital in India. All consecutive patients aged <18 y admitted with COVID-19 were line listed. Patients with current or recently diagnosed TB were included. Consecutive age and sex matched COVID-19 patients with no history of TB were included as controls. Medical records were retrieved, clinical data entered in predetermined proforma. Results: During study period, 327 pediatric COVID-19 patients were admitted. Study group included 17 patients with TB. These patients, tended to be referred from other hospitals, be sicker, had lower SpO2 at arrival and higher severity of COVID-19 as compared to controls (All P < 0.05). They required more mechanical ventilation, had longer length of stay and worse outcome. Conclusion: COVID-19 may secondarily affect and modify the course of TB in children. Given the high case fatality rate in this association and potentially treatable nature of TB, attention of the policy makers is drawn to this.
Indian Journal of Critical Care Medicine, Oct 31, 2022
Background: Paroxysmal sympathetic hyperactivity (PSH) is characterized by the abnormal excessive... more Background: Paroxysmal sympathetic hyperactivity (PSH) is characterized by the abnormal excessive sympathetic response to acute cerebral insult. There is a paucity of data about this condition in children. This study was planned to analyze the incidence of PSH among children requiring neurocritical care and its association with the outcome. Materials and methods: The study was conducted in the pediatric intensive care unit (PICU) of a tertiary care hospital over a period of 10 months. Children of age 1 month to 12 years admitted with neurocritical illnesses were included. Children who were declared brain dead after initial resuscitation were excluded from the study. The criterion laid by Moeller et al. was used for the diagnosis for PSH. Results: During the study period, 54 children requiring neurocritical care were included in the study. The incidence of PSH was 5/54 (9.2%). Additionally, 30 (55.5%) children had less than four criteria for PSH and were termed as "incomplete PSH. " Children with all four criteria for PSH had a significantly longer duration of mechanical ventilation, PICU stay, and higher PRISM III scores. Children with less than four criteria for PSH also had a longer duration of mechanical ventilation and stay. However, there was no significant difference in mortality. Conclusion: Paroxysmal sympathetic hyperactivity is common in children with neurological illnesses admitted to the PICU and is associated with longer mechanical ventilation and stay in PICU. They also had higher illness severity scores. Timely diagnosis of the condition and appropriate management is required to improve the outcome of these children.
Pediatric Critical Care Medicine, 2018
The Lancet Regional Health - Southeast Asia
Journal of Patient Safety & Infection Control, 2015
Journal of neonatal-perinatal medicine, Jan 10, 2015
Acute suppurative parotitis is a rare entity in neonates. Bilateral involvement is extremely rare... more Acute suppurative parotitis is a rare entity in neonates. Bilateral involvement is extremely rare. Low birth weight, prematurity, gavage feeding, dehydration, sepsis are all known risk factors. Staphylococcus aureus is the most common organism, other organisms responsible for parotitis are streptococcus, E. coli, pseudomonas and klebsiella. We report a neonate suffering from bilateral acute suppurative parotitis with an unusual causative association. CPAP and its association for acute suppurative parotitis has been proposed.
Pediatric Critical Care Medicine, 2018
Pediatric Critical Care Medicine, 2021
Pediatric Emergency Care, 2022
Indian Journal of Pediatrics, 2022
To study the clinicoetiological profile of children presenting with acute noninfectious encephalo... more To study the clinicoetiological profile of children presenting with acute noninfectious encephalopathy (NIE) and identify the proportion of children having inborn errors of metabolism (IEM). This descriptive cross sectional study was conducted in a tertiary care centre in Northern India. Consecutive children, aged more than 28 d and less than 12 y, with acute encephalopathy were enrolled after ruling out CNS infection. All children were evaluated on an internally validated structured proforma. A sequential pre-decided battery of tests was applied to determine the cause of encephalopathy. IEM suspects were subjected to TMS/GCMS followed by mutation analysis for confirmation. Fifty children with noninfectious encephalopathy (NIE) were recruited and metabolic causes were detected in 9 of these children (18%), aged 3 to 42 mo, with female preponderance. The IEMs included lactic acidosis (4), glutaric aciduria (3), isovaleric academia (1), and hyperhomocysteinemia (1). History of previously affected siblings and consanguinity between the parents were important indicators of IEM. MS/MS and mutation analysis were the mainstay of diagnosis in these patients. IEMs contributed to the most common cause amongst cases of NIE. IEMs constitute a significant proportion of NIE in India and a high index of suspicion is required to make the diagnosis.
PinG Privacy in Germany, Apr 29, 2014
Journal of Pediatric Neurosciences, 2022
EJIFCC, 2021
Objective To evaluate the electrolyte and lactate abnormalities in hospitalized children using a ... more Objective To evaluate the electrolyte and lactate abnormalities in hospitalized children using a point of care testing (POCT) device and assess the agreement on the electrolyte abnormalities between POCT and central laboratory analyzer with venous blood. Methods This observational study recruited hospitalized children aged 1 month to 12 years within two hours of admission. A paired venous sample and heparinized blood sample were drawn and analyzed by the central laboratory and POCT device (Stat Profile Prime Plus-Nova Biomedical, Waltham, MA, USA) for sodium and potassium. Lactate was measured on the POCT device only. The clinical and outcome parameters of children with electrolyte abnormalities or elevated lactate (>2mmol/L), and the agreement between POCT values and central laboratory values were assessed. Results A total of 158 children with median (IQR) age 11 (6-10) months and PRISM score 5 (2-9) were enrolled. The proportion of children with abnormal sodium and potassium le...
Pediatric Respirology and Critical Care Medicine
Jaypee Brothers Medical Publishers (P) Ltd. eBooks, 2004
Clinical Gastroenterology and Hepatology, Jul 1, 2015
establishing the severity. Periods of hypopnea associated with hypercarbia are the usual findings... more establishing the severity. Periods of hypopnea associated with hypercarbia are the usual findings on sleep studies. Treatment of choice is surgery, which was curative in our case too? Studies decumenting the efficacy of Fluticasone nasal spray for OSA in children due to adenoidotonsilar hypertrophy, have appeared in literature and seem to be encouraging?
DOAJ (DOAJ: Directory of Open Access Journals), 2022
Jaypee Brothers Medical Publishers (P) Ltd. eBooks, 2011
Pediatric Critical Care Medicine, 2018
Journal of Tropical Pediatrics, Jun 6, 2022
Background: Coronavirus disease 2019 (COVID-19) has had devastating effects on the health of mill... more Background: Coronavirus disease 2019 (COVID-19) has had devastating effects on the health of millions globally. Patients with tuberculosis (TB) are a vulnerable population. There is paucity of data to assess association between the 2 diseases in Pediatric population. Objective: To elucidate the effect of concomitant TB on clinical course of pediatric COVID-19 disease. Methods: Retrospective matched cohort study was conducted at dedicated tertiary COVID-19 hospital in India. All consecutive patients aged <18 y admitted with COVID-19 were line listed. Patients with current or recently diagnosed TB were included. Consecutive age and sex matched COVID-19 patients with no history of TB were included as controls. Medical records were retrieved, clinical data entered in predetermined proforma. Results: During study period, 327 pediatric COVID-19 patients were admitted. Study group included 17 patients with TB. These patients, tended to be referred from other hospitals, be sicker, had lower SpO2 at arrival and higher severity of COVID-19 as compared to controls (All P < 0.05). They required more mechanical ventilation, had longer length of stay and worse outcome. Conclusion: COVID-19 may secondarily affect and modify the course of TB in children. Given the high case fatality rate in this association and potentially treatable nature of TB, attention of the policy makers is drawn to this.
Indian Journal of Critical Care Medicine, Oct 31, 2022
Background: Paroxysmal sympathetic hyperactivity (PSH) is characterized by the abnormal excessive... more Background: Paroxysmal sympathetic hyperactivity (PSH) is characterized by the abnormal excessive sympathetic response to acute cerebral insult. There is a paucity of data about this condition in children. This study was planned to analyze the incidence of PSH among children requiring neurocritical care and its association with the outcome. Materials and methods: The study was conducted in the pediatric intensive care unit (PICU) of a tertiary care hospital over a period of 10 months. Children of age 1 month to 12 years admitted with neurocritical illnesses were included. Children who were declared brain dead after initial resuscitation were excluded from the study. The criterion laid by Moeller et al. was used for the diagnosis for PSH. Results: During the study period, 54 children requiring neurocritical care were included in the study. The incidence of PSH was 5/54 (9.2%). Additionally, 30 (55.5%) children had less than four criteria for PSH and were termed as "incomplete PSH. " Children with all four criteria for PSH had a significantly longer duration of mechanical ventilation, PICU stay, and higher PRISM III scores. Children with less than four criteria for PSH also had a longer duration of mechanical ventilation and stay. However, there was no significant difference in mortality. Conclusion: Paroxysmal sympathetic hyperactivity is common in children with neurological illnesses admitted to the PICU and is associated with longer mechanical ventilation and stay in PICU. They also had higher illness severity scores. Timely diagnosis of the condition and appropriate management is required to improve the outcome of these children.
Pediatric Critical Care Medicine, 2018
The Lancet Regional Health - Southeast Asia
Journal of Patient Safety & Infection Control, 2015
Journal of neonatal-perinatal medicine, Jan 10, 2015
Acute suppurative parotitis is a rare entity in neonates. Bilateral involvement is extremely rare... more Acute suppurative parotitis is a rare entity in neonates. Bilateral involvement is extremely rare. Low birth weight, prematurity, gavage feeding, dehydration, sepsis are all known risk factors. Staphylococcus aureus is the most common organism, other organisms responsible for parotitis are streptococcus, E. coli, pseudomonas and klebsiella. We report a neonate suffering from bilateral acute suppurative parotitis with an unusual causative association. CPAP and its association for acute suppurative parotitis has been proposed.
Pediatric Critical Care Medicine, 2018
Pediatric Critical Care Medicine, 2021
Pediatric Emergency Care, 2022
Indian Journal of Pediatrics, 2022
To study the clinicoetiological profile of children presenting with acute noninfectious encephalo... more To study the clinicoetiological profile of children presenting with acute noninfectious encephalopathy (NIE) and identify the proportion of children having inborn errors of metabolism (IEM). This descriptive cross sectional study was conducted in a tertiary care centre in Northern India. Consecutive children, aged more than 28 d and less than 12 y, with acute encephalopathy were enrolled after ruling out CNS infection. All children were evaluated on an internally validated structured proforma. A sequential pre-decided battery of tests was applied to determine the cause of encephalopathy. IEM suspects were subjected to TMS/GCMS followed by mutation analysis for confirmation. Fifty children with noninfectious encephalopathy (NIE) were recruited and metabolic causes were detected in 9 of these children (18%), aged 3 to 42 mo, with female preponderance. The IEMs included lactic acidosis (4), glutaric aciduria (3), isovaleric academia (1), and hyperhomocysteinemia (1). History of previously affected siblings and consanguinity between the parents were important indicators of IEM. MS/MS and mutation analysis were the mainstay of diagnosis in these patients. IEMs contributed to the most common cause amongst cases of NIE. IEMs constitute a significant proportion of NIE in India and a high index of suspicion is required to make the diagnosis.
PinG Privacy in Germany, Apr 29, 2014
Journal of Pediatric Neurosciences, 2022
EJIFCC, 2021
Objective To evaluate the electrolyte and lactate abnormalities in hospitalized children using a ... more Objective To evaluate the electrolyte and lactate abnormalities in hospitalized children using a point of care testing (POCT) device and assess the agreement on the electrolyte abnormalities between POCT and central laboratory analyzer with venous blood. Methods This observational study recruited hospitalized children aged 1 month to 12 years within two hours of admission. A paired venous sample and heparinized blood sample were drawn and analyzed by the central laboratory and POCT device (Stat Profile Prime Plus-Nova Biomedical, Waltham, MA, USA) for sodium and potassium. Lactate was measured on the POCT device only. The clinical and outcome parameters of children with electrolyte abnormalities or elevated lactate (>2mmol/L), and the agreement between POCT values and central laboratory values were assessed. Results A total of 158 children with median (IQR) age 11 (6-10) months and PRISM score 5 (2-9) were enrolled. The proportion of children with abnormal sodium and potassium le...