uzma fatima - Academia.edu (original) (raw)

Papers by uzma fatima

Research paper thumbnail of Comparison of Smart City Development in Japan and China by Text Mining Analysis

Journal of Physics: Conference Series, 2021

With the information technology development, Smart city has become popular worldwide in recent ye... more With the information technology development, Smart city has become popular worldwide in recent years. However, the applications of smart cities are diversified among countries to achieve different objectives. This research compared how the smart city concept has been applied differently in China and Japan, two major economies in East Asia, through text mining techniques on relevant journal articles. The journal articles in either countries are analyzed by software, KH-Coder, which automatically extracts word, count the frequency of each word then using statistic method to classify and find the relationship among each high-frequency word. The results imply that in the case of Japan, energy efficiency in local level is a primary focus while the smart city concept is applied as a basic infrastructure for economic development in China.

Research paper thumbnail of EHG Signal Classification for True and False Pregnancy Analysis

Normally pregnancy last for 40 week, in which babies are born normal and healthy. The babies whic... more Normally pregnancy last for 40 week, in which babies are born normal and healthy. The babies which are born after 20th week and before 37th week of pregnancy are known as premature babies. This can cause deficiency in babies and high risk of death of child, to reduce neonatal death it is necessary to predict whether the labor is term or preterm one of the promising tool to measure the electrical activity of uterine muscle is EHG. Previous paper had done research in acquiring EHG signals, in this paper various EHG signal is acquired and linear and non-linear feature is extracted and is given to support vector machine (SVM) classifier to determine whether the signal is term or preterm.

Research paper thumbnail of EHG Signal Classification for Term and Pre-Term Pregnancy Analysis

International Journal of Scientific Research in Science and Technology, 2017

Early prediction of premature pregnancy reduces neonatal death and helps in adoption of treatment... more Early prediction of premature pregnancy reduces neonatal death and helps in adoption of treatment well suited for the pre-term pregnancy state. There are scads of work done in the area of term and pre-term pregnancy analysis like artificial intelligence, regressive models, and higher order statistical models. This paper proposes a four-level decomposition of Electrohysterography (EHG) signals using Discrete Wavelet Transform (DWT) based on pyramid algorithm to obtain the final feature vector matrix. Classification is done using Support Vector Machines (SVM) by dividing the data into test and training sets. It is validated on a well-known benchmark database from Physionet Database. The proposed method can be used for real time implementation owing to low computational cost, high speed and its feasibility to be implemented on hardware. The encouraging experimental results show that the technique gives an accuracy of 97.8% and can be a promising tool for investigating the risk of prete...

Research paper thumbnail of 11 Hormone, Reproduktion

Research paper thumbnail of Different Mathematical Approaches on Queues

Research paper thumbnail of Automated Navigation System with Indoor Assistance for Blind

Contactless Healthcare Facilitation and Commodity Delivery Management During COVID 19 Pandemic, 2021

Research paper thumbnail of Chemical compositions of leaf extracts from Conocarpus erectus L. (Combretaceae) and their bioactivities against Tribolium castaneum Herbst (Coleoptera: Tenebrionidae)

Journal of Asia-Pacific Entomology, 2019

Abstract Botanical insecticides have long been considered as alternatives to synthetic chemical i... more Abstract Botanical insecticides have long been considered as alternatives to synthetic chemical insecticides in IPM programs. Effects of aqueous and ethanolic extracts obtained from buttonwood, Conocarpus erectus L. (Combretaceae), leaves on a major kind of stored product pests, Tribolium castaneum Herbst (Coleoptera: Tenebrionidae), were evaluated under laboratory conditions. For this purpose, LC50, repellency, antifeedant properties, and some biological effects (including body weight, immature developmental time and survival) of the insect were determined. The aqueous and ethanolic extracts were highly toxic to the larvae and adults. Calculated LC50 values ranged between 2.6 and 193.4 (g/kg). Both extracts had repellent and antifeedant properties against the adults. The extracts adversely affected the larval and pupal weights, developmental time, and survival. Aqueous extracts were more effective only for the LC50 values and only in females. All other measured parameters do not differ between the two extracts. The bioactive properties might be related to high amounts of alkaloid, phenol and tannin. Aqueous extract of the plant leaves may be a useful alternative for chemical insecticides.

Research paper thumbnail of DNA Damage, Response, and Repair in Plants Under Genotoxic Stress

Stress Signaling in Plants: Genomics and Proteomics Perspective, Volume 2, 2016

Several environmental and endogenous factors create a variety of lesions in the genome of an orga... more Several environmental and endogenous factors create a variety of lesions in the genome of an organism. These lesions could potentially be genotoxic and might lead to mutations, which could be lethal. All organisms exhibit a prompt response against DNA damage, which is referred to as the DNA damage response. The existence of elaborate, evolutionarily conserved systems to repair the damage, mostly at the expense of huge amount of energy, points to the importance of safeguarding the integrity of DNA. Most of the current understanding about DNA damage response and repair pathways has been distilled through decades of research on prokaryotes, yeast, and mammalian systems. The response to genotoxic stresses and the repair mechanisms involved in plants has only recently begun to be investigated. Herein, we present a comprehensive account of the types of DNA damage, the DNA damage response, and the repair pathways with reference to the recent insights gained from the plants. Although, the underlying common theme runs through to the plants, the mechanisms in plants demonstrate some unique features. Also, there are several missing links that need to be unravelled for inferring a complete picture. A thorough understanding of the mechanisms involved would aid in devising strategies to help plants avoid irreparable damages to their genome upon exposure to genotoxic agents.

Research paper thumbnail of Insufficient (Sub-native) Helix Content in Soluble/Solid Aggregates of Recombinant and Engineered Forms of IL-2 Throws Light on How Aggregated IL-2 is Biologically Active

The Protein Journal, 2012

Research paper thumbnail of Structures of Differently Aggregated and Precipitated Forms of γB Crystallin: An FTIR Spectroscopic and EM Study

Protein & Peptide Letters, 2010

The lens protein, B-crystallin, precipitates during cataract formation. As a recombinant protein,... more The lens protein, B-crystallin, precipitates during cataract formation. As a recombinant protein, in aqueous solution, B aggregates and precipitates upon heating, cooling, exposure to ultraviolet light, or refolding from a denatured state. We have studied soluble B crystallin, as well as each of the above aggregated forms, to determine whether B's polypeptide chain is differently organized in each form. For this purpose, we used : (a) Fourier Transform Infra Red (FTIR) spectroscopy in the horizontal attenuated total reflectance (HATR) mode, to examine changes in secondary structural content, and (b) transmission electron microscopy (TEM) to examine gross morphological differences. The peak of the B FTIR amide I band shifts from ~1633 cm-1 to ~1618 cm-1 in heat-, UV-and refolding-induced B precipitates, indicating that narrow beta sheets with fewer strands and higher strand twist angles are becoming reorganized into wider, more planar sheets containing larger numbers of shorter strands, with smaller twist angles. In contrast, in cold-induced precipitates, a loss of anti-parallel beta sheet content is observed. This difference is partly explained by the differential effects of temperature on different non-covalent interactions stabilizing protein structures. The native beta sheet content of B crystallin (~50%) is raised in heat-(~60%) and refolding-induced (~58%) precipitates, but lowered in cold-(~41%), and UV-induced (~44%) precipitates. Cold precipitates also display ~26% helical content. All four aggregates have distinctively different morphological characteristics; this appears to be in keeping with their distinctively different secondary structural contents.

Research paper thumbnail of N-Terminal sequencing by mass spectrometry through specific fluorescamine labeling of α-amino groups before tryptic digestion

Analytical Biochemistry, 2011

We present a single-step procedure for the specific mass labeling of unblocked protein N termini.... more We present a single-step procedure for the specific mass labeling of unblocked protein N termini. We show that the dye fluorescamine, which is commonly assumed to require mildly alkaline conditions for undergoing a nonspecific reaction with aand e-amino groups associated with amino acids, in fact shows a specific reaction only with a-amino groups present at protein N termini when mildly acidic conditions are used. We use this finding to label, identify, and sequence the trypsinolysis-derived N-terminal peptide of lysozyme, using only mass spectrometry, to illustrate how this method could be used with other proteins.

Research paper thumbnail of Analysis of Various Signals Acquired from Uterine Contraction to determine true and false labor

Prediction of premature labor is very important factor in this century as the neonatal death rati... more Prediction of premature labor is very important factor in this century as the neonatal death ratio is increasing day by day. For the prediction of labor it is necessary to have uterine contraction signals. Analysis of EHG is Consider proper tool for this aim. EHG record the electric activity of uterine muscle. In this paper the signals is downloaded from the Physionet dataset, the work presented in this paper is to determine True and False labour from the Analysis of various signals which is acquired from Uterine Contraction. Linear (mean, median) and non-linear (entropy) feature is extracted from EHG signals and support vector machine (SVM) is applied for classification to get the result whether the labour is term or pre-term.

Research paper thumbnail of Erratum to: Insufficient (Sub-native) Helix Content in Soluble/Solid Aggregates of Recombinant and Engineered Forms of IL-2 Throws Light on How Aggregated IL-2 is Biologically Active

The protein journal, Jan 21, 2015

Research paper thumbnail of Comparison of Smart City Development in Japan and China by Text Mining Analysis

Journal of Physics: Conference Series, 2021

With the information technology development, Smart city has become popular worldwide in recent ye... more With the information technology development, Smart city has become popular worldwide in recent years. However, the applications of smart cities are diversified among countries to achieve different objectives. This research compared how the smart city concept has been applied differently in China and Japan, two major economies in East Asia, through text mining techniques on relevant journal articles. The journal articles in either countries are analyzed by software, KH-Coder, which automatically extracts word, count the frequency of each word then using statistic method to classify and find the relationship among each high-frequency word. The results imply that in the case of Japan, energy efficiency in local level is a primary focus while the smart city concept is applied as a basic infrastructure for economic development in China.

Research paper thumbnail of EHG Signal Classification for True and False Pregnancy Analysis

Normally pregnancy last for 40 week, in which babies are born normal and healthy. The babies whic... more Normally pregnancy last for 40 week, in which babies are born normal and healthy. The babies which are born after 20th week and before 37th week of pregnancy are known as premature babies. This can cause deficiency in babies and high risk of death of child, to reduce neonatal death it is necessary to predict whether the labor is term or preterm one of the promising tool to measure the electrical activity of uterine muscle is EHG. Previous paper had done research in acquiring EHG signals, in this paper various EHG signal is acquired and linear and non-linear feature is extracted and is given to support vector machine (SVM) classifier to determine whether the signal is term or preterm.

Research paper thumbnail of EHG Signal Classification for Term and Pre-Term Pregnancy Analysis

International Journal of Scientific Research in Science and Technology, 2017

Early prediction of premature pregnancy reduces neonatal death and helps in adoption of treatment... more Early prediction of premature pregnancy reduces neonatal death and helps in adoption of treatment well suited for the pre-term pregnancy state. There are scads of work done in the area of term and pre-term pregnancy analysis like artificial intelligence, regressive models, and higher order statistical models. This paper proposes a four-level decomposition of Electrohysterography (EHG) signals using Discrete Wavelet Transform (DWT) based on pyramid algorithm to obtain the final feature vector matrix. Classification is done using Support Vector Machines (SVM) by dividing the data into test and training sets. It is validated on a well-known benchmark database from Physionet Database. The proposed method can be used for real time implementation owing to low computational cost, high speed and its feasibility to be implemented on hardware. The encouraging experimental results show that the technique gives an accuracy of 97.8% and can be a promising tool for investigating the risk of prete...

Research paper thumbnail of 11 Hormone, Reproduktion

Research paper thumbnail of Different Mathematical Approaches on Queues

Research paper thumbnail of Automated Navigation System with Indoor Assistance for Blind

Contactless Healthcare Facilitation and Commodity Delivery Management During COVID 19 Pandemic, 2021

Research paper thumbnail of Chemical compositions of leaf extracts from Conocarpus erectus L. (Combretaceae) and their bioactivities against Tribolium castaneum Herbst (Coleoptera: Tenebrionidae)

Journal of Asia-Pacific Entomology, 2019

Abstract Botanical insecticides have long been considered as alternatives to synthetic chemical i... more Abstract Botanical insecticides have long been considered as alternatives to synthetic chemical insecticides in IPM programs. Effects of aqueous and ethanolic extracts obtained from buttonwood, Conocarpus erectus L. (Combretaceae), leaves on a major kind of stored product pests, Tribolium castaneum Herbst (Coleoptera: Tenebrionidae), were evaluated under laboratory conditions. For this purpose, LC50, repellency, antifeedant properties, and some biological effects (including body weight, immature developmental time and survival) of the insect were determined. The aqueous and ethanolic extracts were highly toxic to the larvae and adults. Calculated LC50 values ranged between 2.6 and 193.4 (g/kg). Both extracts had repellent and antifeedant properties against the adults. The extracts adversely affected the larval and pupal weights, developmental time, and survival. Aqueous extracts were more effective only for the LC50 values and only in females. All other measured parameters do not differ between the two extracts. The bioactive properties might be related to high amounts of alkaloid, phenol and tannin. Aqueous extract of the plant leaves may be a useful alternative for chemical insecticides.

Research paper thumbnail of DNA Damage, Response, and Repair in Plants Under Genotoxic Stress

Stress Signaling in Plants: Genomics and Proteomics Perspective, Volume 2, 2016

Several environmental and endogenous factors create a variety of lesions in the genome of an orga... more Several environmental and endogenous factors create a variety of lesions in the genome of an organism. These lesions could potentially be genotoxic and might lead to mutations, which could be lethal. All organisms exhibit a prompt response against DNA damage, which is referred to as the DNA damage response. The existence of elaborate, evolutionarily conserved systems to repair the damage, mostly at the expense of huge amount of energy, points to the importance of safeguarding the integrity of DNA. Most of the current understanding about DNA damage response and repair pathways has been distilled through decades of research on prokaryotes, yeast, and mammalian systems. The response to genotoxic stresses and the repair mechanisms involved in plants has only recently begun to be investigated. Herein, we present a comprehensive account of the types of DNA damage, the DNA damage response, and the repair pathways with reference to the recent insights gained from the plants. Although, the underlying common theme runs through to the plants, the mechanisms in plants demonstrate some unique features. Also, there are several missing links that need to be unravelled for inferring a complete picture. A thorough understanding of the mechanisms involved would aid in devising strategies to help plants avoid irreparable damages to their genome upon exposure to genotoxic agents.

Research paper thumbnail of Insufficient (Sub-native) Helix Content in Soluble/Solid Aggregates of Recombinant and Engineered Forms of IL-2 Throws Light on How Aggregated IL-2 is Biologically Active

The Protein Journal, 2012

Research paper thumbnail of Structures of Differently Aggregated and Precipitated Forms of γB Crystallin: An FTIR Spectroscopic and EM Study

Protein & Peptide Letters, 2010

The lens protein, B-crystallin, precipitates during cataract formation. As a recombinant protein,... more The lens protein, B-crystallin, precipitates during cataract formation. As a recombinant protein, in aqueous solution, B aggregates and precipitates upon heating, cooling, exposure to ultraviolet light, or refolding from a denatured state. We have studied soluble B crystallin, as well as each of the above aggregated forms, to determine whether B's polypeptide chain is differently organized in each form. For this purpose, we used : (a) Fourier Transform Infra Red (FTIR) spectroscopy in the horizontal attenuated total reflectance (HATR) mode, to examine changes in secondary structural content, and (b) transmission electron microscopy (TEM) to examine gross morphological differences. The peak of the B FTIR amide I band shifts from ~1633 cm-1 to ~1618 cm-1 in heat-, UV-and refolding-induced B precipitates, indicating that narrow beta sheets with fewer strands and higher strand twist angles are becoming reorganized into wider, more planar sheets containing larger numbers of shorter strands, with smaller twist angles. In contrast, in cold-induced precipitates, a loss of anti-parallel beta sheet content is observed. This difference is partly explained by the differential effects of temperature on different non-covalent interactions stabilizing protein structures. The native beta sheet content of B crystallin (~50%) is raised in heat-(~60%) and refolding-induced (~58%) precipitates, but lowered in cold-(~41%), and UV-induced (~44%) precipitates. Cold precipitates also display ~26% helical content. All four aggregates have distinctively different morphological characteristics; this appears to be in keeping with their distinctively different secondary structural contents.

Research paper thumbnail of N-Terminal sequencing by mass spectrometry through specific fluorescamine labeling of α-amino groups before tryptic digestion

Analytical Biochemistry, 2011

We present a single-step procedure for the specific mass labeling of unblocked protein N termini.... more We present a single-step procedure for the specific mass labeling of unblocked protein N termini. We show that the dye fluorescamine, which is commonly assumed to require mildly alkaline conditions for undergoing a nonspecific reaction with aand e-amino groups associated with amino acids, in fact shows a specific reaction only with a-amino groups present at protein N termini when mildly acidic conditions are used. We use this finding to label, identify, and sequence the trypsinolysis-derived N-terminal peptide of lysozyme, using only mass spectrometry, to illustrate how this method could be used with other proteins.

Research paper thumbnail of Analysis of Various Signals Acquired from Uterine Contraction to determine true and false labor

Prediction of premature labor is very important factor in this century as the neonatal death rati... more Prediction of premature labor is very important factor in this century as the neonatal death ratio is increasing day by day. For the prediction of labor it is necessary to have uterine contraction signals. Analysis of EHG is Consider proper tool for this aim. EHG record the electric activity of uterine muscle. In this paper the signals is downloaded from the Physionet dataset, the work presented in this paper is to determine True and False labour from the Analysis of various signals which is acquired from Uterine Contraction. Linear (mean, median) and non-linear (entropy) feature is extracted from EHG signals and support vector machine (SVM) is applied for classification to get the result whether the labour is term or pre-term.

Research paper thumbnail of Erratum to: Insufficient (Sub-native) Helix Content in Soluble/Solid Aggregates of Recombinant and Engineered Forms of IL-2 Throws Light on How Aggregated IL-2 is Biologically Active

The protein journal, Jan 21, 2015