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Using 4-chlorobenzohydrazide as a source of amine and substituted aromatic aldehydes as a carbony... more Using 4-chlorobenzohydrazide as a source of amine and substituted aromatic aldehydes as a carbonyl source, concentrated hydrochloric acid as catalyst at room temperature 4-chlorobenzohydrazide derivatives was synthesized. The compounds (S5-S6) were characterized by FT-IR, 1 H NMR and 13 C NMR. The compounds were screened for antimicrobial activity against S. aureus, E. coli and A. niger. The antioxidant activities of synthesized Schiff bases were investigated using the DPPH radical scavenging method. The designed compounds were further subjected for molecular docking study by in silico method to analyse anti-tuberculosis against InhA, the enoyl acyl carrier protein reductase (ENR) from Mycobacterium tuberculosis by Discover studio 2.1version software.

Using 4-chlorobenzohydrazide as a source of amine and substituted aromatic aldehydes as a carbony... more Using 4-chlorobenzohydrazide as a source of amine and substituted aromatic aldehydes as a carbonyl source, concentrated hydrochloric acid as catalyst at room temperature 4-chlorobenzohydrazide derivatives was synthesized. The structures of newly synthesized compounds have been supported by (S5-S6) FT-IR, 1H NMR and 13C NMR spectral studies. The compounds were screened for antimicrobial activity against S. aureus, E. coli and A. niger.

In the present article, a series of Schiff bases have been derived from aromatic aldehydes with a... more In the present article, a series of Schiff bases have been derived from aromatic aldehydes with acid hydrazide and using concentrated hydrochloric acid as catalyst. The synthesized compounds are (benzohydrazide (S4) were characterized through FT-IR, 1 H NMR and 13 C NMR. These synthesized compounds have been screened for antimicrobial activity against S. aureus, E. coli and A. niger. The antioxidant activity of Schiff bases were investigated by DPPH radical scavenging method using UV spectrum. The designed compounds were further subjected for molecular docking studies for 2NSD protein in Mycobacterium tuberculosis by Discover studio 2.1version software.

Steve Abrams, IBM, USA Ban Al-Ani, University of California Irvine, USA Muhammad Ali Babar, IT Un... more Steve Abrams, IBM, USA Ban Al-Ani, University of California Irvine, USA Muhammad Ali Babar, IT University of Copenhagen, Denmark Alberto Avritzer, Siemens, USA Raja Bavani, MindTree, India Bernd Bruegge, Technische Universität München, Germany Fabio Calefato, University of Bari, Italy Marcelo Cataldo, CMU, USA Darren Dalcher, Middlesex University, United Kingdom Daniela Damian, University of Victoria, Canada Cleidson RB de Souza, UFPA, Brazil Yael Dubinsky, IBM Haifa Research Lab, Israel Kevin Dullemond, Delft University of ...

Using 4-chlorobenzohydrazide as a source of amine and substituted aromatic aldehydes as a carbony... more Using 4-chlorobenzohydrazide as a source of amine and substituted aromatic aldehydes as a carbonyl source, concentrated hydrochloric acid as catalyst at room temperature 4-chlorobenzohydrazide derivatives was synthesized. The compounds (S5-S6) were characterized by FT-IR, 1 H NMR and 13 C NMR. The compounds were screened for antimicrobial activity against S. aureus, E. coli and A. niger. The antioxidant activities of synthesized Schiff bases were investigated using the DPPH radical scavenging method. The designed compounds were further subjected for molecular docking study by in silico method to analyse anti-tuberculosis against InhA, the enoyl acyl carrier protein reductase (ENR) from Mycobacterium tuberculosis by Discover studio 2.1version software.

Using 4-chlorobenzohydrazide as a source of amine and substituted aromatic aldehydes as a carbony... more Using 4-chlorobenzohydrazide as a source of amine and substituted aromatic aldehydes as a carbonyl source, concentrated hydrochloric acid as catalyst at room temperature 4-chlorobenzohydrazide derivatives was synthesized. The structures of newly synthesized compounds have been supported by (S5-S6) FT-IR, 1H NMR and 13C NMR spectral studies. The compounds were screened for antimicrobial activity against S. aureus, E. coli and A. niger.

In the present article, a series of Schiff bases have been derived from aromatic aldehydes with a... more In the present article, a series of Schiff bases have been derived from aromatic aldehydes with acid hydrazide and using concentrated hydrochloric acid as catalyst. The synthesized compounds are (benzohydrazide (S4) were characterized through FT-IR, 1 H NMR and 13 C NMR. These synthesized compounds have been screened for antimicrobial activity against S. aureus, E. coli and A. niger. The antioxidant activity of Schiff bases were investigated by DPPH radical scavenging method using UV spectrum. The designed compounds were further subjected for molecular docking studies for 2NSD protein in Mycobacterium tuberculosis by Discover studio 2.1version software.

Steve Abrams, IBM, USA Ban Al-Ani, University of California Irvine, USA Muhammad Ali Babar, IT Un... more Steve Abrams, IBM, USA Ban Al-Ani, University of California Irvine, USA Muhammad Ali Babar, IT University of Copenhagen, Denmark Alberto Avritzer, Siemens, USA Raja Bavani, MindTree, India Bernd Bruegge, Technische Universität München, Germany Fabio Calefato, University of Bari, Italy Marcelo Cataldo, CMU, USA Darren Dalcher, Middlesex University, United Kingdom Daniela Damian, University of Victoria, Canada Cleidson RB de Souza, UFPA, Brazil Yael Dubinsky, IBM Haifa Research Lab, Israel Kevin Dullemond, Delft University of ...