waad farhat - Academia.edu (original) (raw)
Papers by waad farhat
Journal de Chirurgie Viscérale, 2021
But L’objectif de notre etude etait d’evaluer l’interet de l’index de fragilite modifie (mFI-11) ... more But L’objectif de notre etude etait d’evaluer l’interet de l’index de fragilite modifie (mFI-11) dans la prediction des fistules anastomotiques (FA) apres chirurgie colorectale. Materiels et methodes Il s’agit d’une etude prospective bicentrique. Le pouvoir predictif du mFI-11 a ete atteste par deux manieres : – l’aire sous courbe en utilisant les courbes caracteristiques de performance (ROC), avec etude de la sensibilite et de la specificite ; – analyse uni- et multivariee pour determiner le poids du mFI-11 dans la prediction des FA apres chirurgie colorectale. Resultats Nous avons collige 192 patients au cours d’un an d’etude. Le taux de FA etait 17,2 % (33 patients). Une reprise chirurgicale a ete realisee pour 10 patients. Trois patients ont eu un drainage percutane, 50,3 % etaient classes non fragiles, 34,9 % des patients etaient a fragilite faible, 10,8 % des patients etaient a fragilite intermediaire et 4 % a forte fragilite. Le meilleur seuil de mFI-11 pour predire les FA et...
Journal de Chirurgie Viscérale, 2021
2019 6th International Conference on Control, Decision and Information Technologies (CoDIT), 2019
Pancreatic cysts may have a significant malignant potential and their identification represents a... more Pancreatic cysts may have a significant malignant potential and their identification represents a ‘window of opportunity’ for the early detection of pancreatic cancer. Previous works have achieved certain accuracy for classification on segmented cystic lesions in CT. However, pancreatic cysts have a large variation in size and shape, and the precise results of its segmentation remains rather challenging, for which we propose a disease-diagnosis ontology for early differential diagnosis of pancreatic cysts without pre-segmenting the lesions using an ontology-based-classification. Disease-diagnosis ontology is being developed to model and represent diagnosis information found in medical abstracts. The ontology studies the high-level features of cysts and builds mappings between medical imaging appearances to different pathological types of pancreatic cysts. To improve clinical applicability, we integrate a classifier of each cyst based on the results of past patients. The test on a group of 73 patients' pancreatic lesion cystic pathologically confirmed, reached an overall accuracy of 86%, which is significantly higher than the previous accuracy of 51.4%, which strongly reinforces the clinical potential of our developed method. In this article, we present the architecture of the approach, the key processes, and the first steps of the experimental validation through the developed feasibility model.
Pan African Medical Journal, 2017
Nous rapportons l'observation de deux cas présentant une occlusion intestinale aiguë. L'intervent... more Nous rapportons l'observation de deux cas présentant une occlusion intestinale aiguë. L'intervention en urgence a trouvé une hernie paraduodénale gauche obstructive à l'origine d'un volvulus, avec nécrose des anses grêles incarcérées pour un patient, traité par résection anastomose en un temps et un grêle souffrant mais viable pour le deuxième malade, traité par la réduction du grêle incarcéré et l'obturation de l'orifice herniaire. Nous discutons à l'occasion de ces observations les particularités diagnostiques et thérapeutiques de cette affection rare.
Journal de Chirurgie Viscérale, 2021
But Determiner les facteurs epidemiologiques, clinicobiologiques, endoscopiques et therapeutiques... more But Determiner les facteurs epidemiologiques, clinicobiologiques, endoscopiques et therapeutiques associes au risque de colectomie chez des patients presentant une CAG corticoresistante. Materiel et methodes Nous avons mene une etude retrospective sur 10 ans colligeant les patients hospitalises pour une RCH compliquee de CAG corticoresistante. Le diagnostic de CAG etait retenu selon les criteres d’Oxford modifies. Resultats Durant la periode de l’etude, 75 patients ont ete colliges. L’âge moyen au moment du diagnostic de la RCH etait 45 ans. Il s’agit de 30 hommes et 45 femmes suivis sur une periode moyenne de 34,66 mois [6–120 mois]. Les antecedents familiaux de MICI ont ete notes chez 6 patients. La CAG etait inaugurale chez 24 patients (42,1 %) et emaillant l’evolution de la maladie chez 33 patients (57,9 %), survenant apres un delai moyen de 8 ans par rapport a la de decouverte de RCH. Le recours a la colectomie etait necessaire chez 26 patients (45,61 %). L’indication de la colectomie etait : un echec du traitement par la ciclosporine chez 18 patients et suite a une recidive d’une poussee severe sous thiopurines chez 8 malades avec un delai moyen de 9,6 mois [2–22 mois]. Les facteurs associes a un risque accru de colectomie au cours d’une CAG corticoresistante etaient : l’antecedent d’une CAG (p = 0,039), un traitement anterieur par les thiopurines (p = 0,043) ainsi qu’un taux d’albumine inferieur a 30 g/L (p = 0,026). Conclusion L’antecedent d’une CAG, le traitement par thiopurines ainsi qu’une albuminemie
2019 6th International Conference on Control, Decision and Information Technologies (CoDIT)
Annals of Medicine and Surgery
Annals of Medicine and Surgery
Clinical Journal of Gastroenterology
Acta Scientific Gastrointestinal Disorders
Annals of Medicine and Surgery
World Journal of Surgical Oncology
Background The recurrence after curative surgery of the rectal adenocarcinoma is a serious compli... more Background The recurrence after curative surgery of the rectal adenocarcinoma is a serious complication, considered as a failure of the therapeutic strategy. The aim of this study was to identify the different prognostic factors affecting the recurrence of adenocarcinoma of the rectum. Methods A retrospective analysis of patients operated for adenocarcinoma of the rectum between January 2000 and December 2015 was conducted. The study of the recurrence rate and prognostic factors was performed through the Kaplan Meier survival curve and the Cox regression analysis. Results During the study period, 188 patients underwent curative surgery for rectal adenocarcinoma, among which 53 had a recurrence. The recurrence rate was 44.6% at 5 years. The multivariate analysis identified four parameters independently associated with the risk of recurrence after curative surgery: a distal margin ≤ 2 cm (HR = 6.8, 95% CI 2.7–16.6, 6), extracapsular invasion of lymph node metastasis (HR = 4.4, 95% CI ...
Insights into Imaging
Neurofibromatosis type 1 (NF1) is one of the most common genetic disorders. Gastrointestinal mani... more Neurofibromatosis type 1 (NF1) is one of the most common genetic disorders. Gastrointestinal manifestations of NF-1 are seldom thought of in routine clinical practice and might thus be significantly under-recognised. Their heterogeneous spectrum ranges from localised microscopic proliferative lesions to grossly recognizable mass-forming neurofibromas, neuroendocrine and gastrointestinal stromal tumours (GIST). The aim of this study is discussing the imaging evaluation and characterisation of the abdomen lesions in patients with NF1. Teaching Points • Neurofibromatosis type (NF-1) is one of the most common single gene disorders. • Every organ system can be involved and intra-abdominal manifestations are underestimated. • The NF1 abdominal manifestations comprehend five categories of tumours. • Neurogenic tumours including with neurofibromas are the most common type. • Early diagnosis of abdominal manifestations of NF-1 based on imaging patterns is necessary for appropriate treatment to avoid serious organic complications related to tumour mass.
International Journal of Surgery Case Reports
INTRODUCTION: Patients with appendicular endometriosis (AE) constitute <1% cases of all pe... more INTRODUCTION: Patients with appendicular endometriosis (AE) constitute <1% cases of all pelvic endometriosis cases. AE presents with pain in right iliac fossa and symptomatically mimics appendicitis and definitive diagnosis is possible only after histopathological examination of excised appendix. PRESENTATION OF CASE: In this case report, we present a rare case of appendicular endometriosis in a young woman suffering from pain in right iliac fossa and periumbilical region (on/off) for the past one year. She had a past history of infertility. Blood investigations were normal and CT scan of abdomen demonstrated findings suggestive of appendicitis. Laparoscopic appendicectomy was performed, which revealed 2 cm tumor-like mass (1.5 cm diameter) present at the tip of appendix involving the mesoappendix. There was no ascites, peritoneal or omental deposits or any signs of inflammation. Post-operative recovery was good. Dissected appendix specimen was sent for histopathological examination which confirmed endometriosis of appendix. DISCUSSION: Gastrointestinal endometriosis (GE) accounts for 3–37% of all endometriosis cases, whereas AE is present in only ∼3% of all GE cases and constitutes <1% of all the endometriosis cases. AE frequently involves tip and body of the appendix. The layers of appendix most commonly affected are muscular and seromuscular (∼2/3rd cases), followed by the serosa (∼1/3rd cases). CONCLUSION: Thus, appendicular endometriosis is a rare entity and should be included in differential diagnosis in young women presenting with pain in right iliac fossa and having history of infertility
International Journal of Surgery Case Reports
INTRODUCTION: Omentum is a well vascularized organ. Omentum infarction is uncommon. Most of the c... more INTRODUCTION: Omentum is a well vascularized organ. Omentum infarction is uncommon. Most of the cases are secondary due to torsion, intra-abdominal infections and vascular thrombosis. Primary idiopathic segmental omental infarction is rare. PRESENTATION OF CASE: A 26-year-old male presented with acute onset right iliac fossa pain mimicking acute appendicitis. On radiological imaging, early acute appendicitis was suspected. On diagnostic laparoscopy, appendix appeared normal and there was idiopathic infarction of a part of the greater omentum lying close to the cecum. Patient underwent laparoscopic appendectomy with excision of the diseased segment of the omentum and had uneventful recovery. CONCLUSION:Idiopathic omental infarction should be included in the differential diagnoses while treating patient with acute abdomen.
International Journal of Surgery Case Reports
Introduction: Gallbladder volvulus (GV) is a rare disease with less than 400 cases reported in th... more Introduction: Gallbladder volvulus (GV) is a rare disease with less than 400 cases reported in the English literature. The pre-operative diagnosis of GV is difficult as none of the imaging modalities are accurate. Once diagnosed, the mainstay of treatment is emergency surgical derotation and cholecystectomy. Presentation of case: A 83-old lady presented with right upper quadrant pain and fever for 3 days. Abdominal imaging revealed the presence of a distended, floating gallbladder located outside its normal fossa with thickened non-enhancing wall and a twisted pedicle suggestive GV. The patient underwent emergency laparotomy because the laparoscopic approach was refused by the anesthetist due to the history of pulmonary emphysema. Intraoperatively, the gallbladder was found be gangrenous and rotated in anticlockwise direction around the cystic pedicle. The gallbladder was de-rotated followed by chole-cystectomy. Discussion: GV is an uncommon cause for abdominal pain and occurs due to rotation of gall bladder on its mesentery along the axis of the cystic duct and the cystic artery. Pre-operative diagnosis continues to be a major challenge with only 4 cases reported in the literature diagnosed with pre-operative imaging. This case is one of the rare cases diagnosed with pre-operative imaging. It is often misdiagnosed as acute cholecystitis before surgery. However, critical constellation of presenting signs and symptoms along with radiological findings may guide the surgeon to accurate and timely diagnosis of GV before surgical intervention. Conclusion: Although rare, it is important to consider GV as a differential diagnosis in an elderly patient with acute cholecystitis.
Presse medicale (Paris, France : 1983), Jan 24, 2018
Journal of Gastroenterology and Hepatology Research, 2015
Journal of Gastroenterology and Hepatology Research, 2014
Journal de Chirurgie Viscérale, 2021
But L’objectif de notre etude etait d’evaluer l’interet de l’index de fragilite modifie (mFI-11) ... more But L’objectif de notre etude etait d’evaluer l’interet de l’index de fragilite modifie (mFI-11) dans la prediction des fistules anastomotiques (FA) apres chirurgie colorectale. Materiels et methodes Il s’agit d’une etude prospective bicentrique. Le pouvoir predictif du mFI-11 a ete atteste par deux manieres : – l’aire sous courbe en utilisant les courbes caracteristiques de performance (ROC), avec etude de la sensibilite et de la specificite ; – analyse uni- et multivariee pour determiner le poids du mFI-11 dans la prediction des FA apres chirurgie colorectale. Resultats Nous avons collige 192 patients au cours d’un an d’etude. Le taux de FA etait 17,2 % (33 patients). Une reprise chirurgicale a ete realisee pour 10 patients. Trois patients ont eu un drainage percutane, 50,3 % etaient classes non fragiles, 34,9 % des patients etaient a fragilite faible, 10,8 % des patients etaient a fragilite intermediaire et 4 % a forte fragilite. Le meilleur seuil de mFI-11 pour predire les FA et...
Journal de Chirurgie Viscérale, 2021
2019 6th International Conference on Control, Decision and Information Technologies (CoDIT), 2019
Pancreatic cysts may have a significant malignant potential and their identification represents a... more Pancreatic cysts may have a significant malignant potential and their identification represents a ‘window of opportunity’ for the early detection of pancreatic cancer. Previous works have achieved certain accuracy for classification on segmented cystic lesions in CT. However, pancreatic cysts have a large variation in size and shape, and the precise results of its segmentation remains rather challenging, for which we propose a disease-diagnosis ontology for early differential diagnosis of pancreatic cysts without pre-segmenting the lesions using an ontology-based-classification. Disease-diagnosis ontology is being developed to model and represent diagnosis information found in medical abstracts. The ontology studies the high-level features of cysts and builds mappings between medical imaging appearances to different pathological types of pancreatic cysts. To improve clinical applicability, we integrate a classifier of each cyst based on the results of past patients. The test on a group of 73 patients' pancreatic lesion cystic pathologically confirmed, reached an overall accuracy of 86%, which is significantly higher than the previous accuracy of 51.4%, which strongly reinforces the clinical potential of our developed method. In this article, we present the architecture of the approach, the key processes, and the first steps of the experimental validation through the developed feasibility model.
Pan African Medical Journal, 2017
Nous rapportons l'observation de deux cas présentant une occlusion intestinale aiguë. L'intervent... more Nous rapportons l'observation de deux cas présentant une occlusion intestinale aiguë. L'intervention en urgence a trouvé une hernie paraduodénale gauche obstructive à l'origine d'un volvulus, avec nécrose des anses grêles incarcérées pour un patient, traité par résection anastomose en un temps et un grêle souffrant mais viable pour le deuxième malade, traité par la réduction du grêle incarcéré et l'obturation de l'orifice herniaire. Nous discutons à l'occasion de ces observations les particularités diagnostiques et thérapeutiques de cette affection rare.
Journal de Chirurgie Viscérale, 2021
But Determiner les facteurs epidemiologiques, clinicobiologiques, endoscopiques et therapeutiques... more But Determiner les facteurs epidemiologiques, clinicobiologiques, endoscopiques et therapeutiques associes au risque de colectomie chez des patients presentant une CAG corticoresistante. Materiel et methodes Nous avons mene une etude retrospective sur 10 ans colligeant les patients hospitalises pour une RCH compliquee de CAG corticoresistante. Le diagnostic de CAG etait retenu selon les criteres d’Oxford modifies. Resultats Durant la periode de l’etude, 75 patients ont ete colliges. L’âge moyen au moment du diagnostic de la RCH etait 45 ans. Il s’agit de 30 hommes et 45 femmes suivis sur une periode moyenne de 34,66 mois [6–120 mois]. Les antecedents familiaux de MICI ont ete notes chez 6 patients. La CAG etait inaugurale chez 24 patients (42,1 %) et emaillant l’evolution de la maladie chez 33 patients (57,9 %), survenant apres un delai moyen de 8 ans par rapport a la de decouverte de RCH. Le recours a la colectomie etait necessaire chez 26 patients (45,61 %). L’indication de la colectomie etait : un echec du traitement par la ciclosporine chez 18 patients et suite a une recidive d’une poussee severe sous thiopurines chez 8 malades avec un delai moyen de 9,6 mois [2–22 mois]. Les facteurs associes a un risque accru de colectomie au cours d’une CAG corticoresistante etaient : l’antecedent d’une CAG (p = 0,039), un traitement anterieur par les thiopurines (p = 0,043) ainsi qu’un taux d’albumine inferieur a 30 g/L (p = 0,026). Conclusion L’antecedent d’une CAG, le traitement par thiopurines ainsi qu’une albuminemie
2019 6th International Conference on Control, Decision and Information Technologies (CoDIT)
Annals of Medicine and Surgery
Annals of Medicine and Surgery
Clinical Journal of Gastroenterology
Acta Scientific Gastrointestinal Disorders
Annals of Medicine and Surgery
World Journal of Surgical Oncology
Background The recurrence after curative surgery of the rectal adenocarcinoma is a serious compli... more Background The recurrence after curative surgery of the rectal adenocarcinoma is a serious complication, considered as a failure of the therapeutic strategy. The aim of this study was to identify the different prognostic factors affecting the recurrence of adenocarcinoma of the rectum. Methods A retrospective analysis of patients operated for adenocarcinoma of the rectum between January 2000 and December 2015 was conducted. The study of the recurrence rate and prognostic factors was performed through the Kaplan Meier survival curve and the Cox regression analysis. Results During the study period, 188 patients underwent curative surgery for rectal adenocarcinoma, among which 53 had a recurrence. The recurrence rate was 44.6% at 5 years. The multivariate analysis identified four parameters independently associated with the risk of recurrence after curative surgery: a distal margin ≤ 2 cm (HR = 6.8, 95% CI 2.7–16.6, 6), extracapsular invasion of lymph node metastasis (HR = 4.4, 95% CI ...
Insights into Imaging
Neurofibromatosis type 1 (NF1) is one of the most common genetic disorders. Gastrointestinal mani... more Neurofibromatosis type 1 (NF1) is one of the most common genetic disorders. Gastrointestinal manifestations of NF-1 are seldom thought of in routine clinical practice and might thus be significantly under-recognised. Their heterogeneous spectrum ranges from localised microscopic proliferative lesions to grossly recognizable mass-forming neurofibromas, neuroendocrine and gastrointestinal stromal tumours (GIST). The aim of this study is discussing the imaging evaluation and characterisation of the abdomen lesions in patients with NF1. Teaching Points • Neurofibromatosis type (NF-1) is one of the most common single gene disorders. • Every organ system can be involved and intra-abdominal manifestations are underestimated. • The NF1 abdominal manifestations comprehend five categories of tumours. • Neurogenic tumours including with neurofibromas are the most common type. • Early diagnosis of abdominal manifestations of NF-1 based on imaging patterns is necessary for appropriate treatment to avoid serious organic complications related to tumour mass.
International Journal of Surgery Case Reports
INTRODUCTION: Patients with appendicular endometriosis (AE) constitute <1% cases of all pe... more INTRODUCTION: Patients with appendicular endometriosis (AE) constitute <1% cases of all pelvic endometriosis cases. AE presents with pain in right iliac fossa and symptomatically mimics appendicitis and definitive diagnosis is possible only after histopathological examination of excised appendix. PRESENTATION OF CASE: In this case report, we present a rare case of appendicular endometriosis in a young woman suffering from pain in right iliac fossa and periumbilical region (on/off) for the past one year. She had a past history of infertility. Blood investigations were normal and CT scan of abdomen demonstrated findings suggestive of appendicitis. Laparoscopic appendicectomy was performed, which revealed 2 cm tumor-like mass (1.5 cm diameter) present at the tip of appendix involving the mesoappendix. There was no ascites, peritoneal or omental deposits or any signs of inflammation. Post-operative recovery was good. Dissected appendix specimen was sent for histopathological examination which confirmed endometriosis of appendix. DISCUSSION: Gastrointestinal endometriosis (GE) accounts for 3–37% of all endometriosis cases, whereas AE is present in only ∼3% of all GE cases and constitutes <1% of all the endometriosis cases. AE frequently involves tip and body of the appendix. The layers of appendix most commonly affected are muscular and seromuscular (∼2/3rd cases), followed by the serosa (∼1/3rd cases). CONCLUSION: Thus, appendicular endometriosis is a rare entity and should be included in differential diagnosis in young women presenting with pain in right iliac fossa and having history of infertility
International Journal of Surgery Case Reports
INTRODUCTION: Omentum is a well vascularized organ. Omentum infarction is uncommon. Most of the c... more INTRODUCTION: Omentum is a well vascularized organ. Omentum infarction is uncommon. Most of the cases are secondary due to torsion, intra-abdominal infections and vascular thrombosis. Primary idiopathic segmental omental infarction is rare. PRESENTATION OF CASE: A 26-year-old male presented with acute onset right iliac fossa pain mimicking acute appendicitis. On radiological imaging, early acute appendicitis was suspected. On diagnostic laparoscopy, appendix appeared normal and there was idiopathic infarction of a part of the greater omentum lying close to the cecum. Patient underwent laparoscopic appendectomy with excision of the diseased segment of the omentum and had uneventful recovery. CONCLUSION:Idiopathic omental infarction should be included in the differential diagnoses while treating patient with acute abdomen.
International Journal of Surgery Case Reports
Introduction: Gallbladder volvulus (GV) is a rare disease with less than 400 cases reported in th... more Introduction: Gallbladder volvulus (GV) is a rare disease with less than 400 cases reported in the English literature. The pre-operative diagnosis of GV is difficult as none of the imaging modalities are accurate. Once diagnosed, the mainstay of treatment is emergency surgical derotation and cholecystectomy. Presentation of case: A 83-old lady presented with right upper quadrant pain and fever for 3 days. Abdominal imaging revealed the presence of a distended, floating gallbladder located outside its normal fossa with thickened non-enhancing wall and a twisted pedicle suggestive GV. The patient underwent emergency laparotomy because the laparoscopic approach was refused by the anesthetist due to the history of pulmonary emphysema. Intraoperatively, the gallbladder was found be gangrenous and rotated in anticlockwise direction around the cystic pedicle. The gallbladder was de-rotated followed by chole-cystectomy. Discussion: GV is an uncommon cause for abdominal pain and occurs due to rotation of gall bladder on its mesentery along the axis of the cystic duct and the cystic artery. Pre-operative diagnosis continues to be a major challenge with only 4 cases reported in the literature diagnosed with pre-operative imaging. This case is one of the rare cases diagnosed with pre-operative imaging. It is often misdiagnosed as acute cholecystitis before surgery. However, critical constellation of presenting signs and symptoms along with radiological findings may guide the surgeon to accurate and timely diagnosis of GV before surgical intervention. Conclusion: Although rare, it is important to consider GV as a differential diagnosis in an elderly patient with acute cholecystitis.
Presse medicale (Paris, France : 1983), Jan 24, 2018
Journal of Gastroenterology and Hepatology Research, 2015
Journal of Gastroenterology and Hepatology Research, 2014