yang huang - Academia.edu (original) (raw)
Papers by yang huang
Cellulose, 2014
Bacterial cellulose (BC) produced by some microorganisms has been widely accepted as a multifunct... more Bacterial cellulose (BC) produced by some microorganisms has been widely accepted as a multifunctional nano-biomaterial. It is composed of linear glucan molecules attached with hydrogen bonds, which appears similar to plant cellulose. However, when compared with other conventional natural or synthesized counterparts, BC performs better in areas such as biomedicine, functional devices, water treatment, nanofillers, etc. for its distinct superior chemical purity, crystallinity, biocompatibility, and ultrafine network architecture. When BC is incorporated in a material or used as a scaffold, novel features result that are related to BC's intrinsic characteristics mentioned above. This review mainly summarizes the recent developments of the functional products fabricated with BC. Besides, the controllable cultivation conditions should also be discussed for expecting to make a breakthrough in its productivity. We highlight the literatures mainly in last 5 years, exerting ourselves to provide the state-ofthe-art opinions in areas wherever are focused on for BC researching.
Cell, 2001
The Slit protein guides neuronal and leukocyte migration through the transmembrane receptor Round... more The Slit protein guides neuronal and leukocyte migration through the transmembrane receptor Roundabout (Robo). We report here that the intracellular domain of Robo interacts with a novel family of Rho GTPase activating proteins (GAPs). Two of the Slit-Robo GAPs (srGAPs) are expressed in regions responsive to Slit. Slit increased srGAP1-Robo1 interaction and inactivated Cdc42. A dominant negative srGAP1 blocked Slit
Journal of Physical Chemistry B, 2006
Uniform and well-crystallized -Ga 2 O 3 nanowires are prepared by reacting metal Ga with water va... more Uniform and well-crystallized -Ga 2 O 3 nanowires are prepared by reacting metal Ga with water vapor based on the vapor-liquid-solid (VLS) mechanism. Electron microscopy studies show that the nanowires have diameters ranging from 10 to 40 nm and lengths up to tens of micrometers. The contact properties of individual Ga 2 O 3 nanowires with Pt or Au/Ti electrodes are studied, respectively, finding that Pt can form Schottkybarrier junctions and Au/Ti is advantageous to fabricate ohmic contacts with individual Ga 2 O 3 nanowires. In ambient air, the conductivity of the Ga 2 O 3 nanowires is about 1 (Ω‚m) -1 , while with adsorption of NH 3 (or NO 2 ) molecules, the conductivity can increase (or decrease) dramatically at room temperature. The as-grown Ga 2 O 3 nanowires have the properties of an n-type semiconductor.
Nanotechnology - NANOTECHNOL, 2008
Quaternary mixed-valence compound TlIn4S5Cl micro- and nanowires are prepared by partial substitu... more Quaternary mixed-valence compound TlIn4S5Cl micro- and nanowires are prepared by partial substitution of chalcogen with halogen starting from a stoichiometric mixture of TlCl, In and S. Their electrical conductivity and gas sensitivity properties are investigated by using standard four-terminal systems. The specific nanowire resistivity is about 107 Omega cm and corresponds to the value of a typical undoped semiconductor in air. This resistivity is, however, extremely sensitive to NO2 (sensitivity about 150) or NH3, with a rapid response of about 2 s and recovery times. This phenomenon is supposed to be particularly important for future nanodevice applications.
Israel Journal of Chemistry, 2010
Herein the recent experiments performed by the authors on fabricated multi-walled BN nanotubes an... more Herein the recent experiments performed by the authors on fabricated multi-walled BN nanotubes and monoatomic BN graphene-like nanosheets are reviewed. The results are presented in several sections, namely: (i) method for high-yield synthesis of thin, defect-free BN nanotubes of only a few-layers, with external diameters below 10 nm; (ii) verification of BN nanotube piezoelectrical behavior and its electrically-induced thermal decomposition under combined resistive heating and electrical charging in a transmission electron microscope; (iii) the first direct measurements of the true tensile strength and Young's modulus of BN nanotubes, using newly developed nanotensile tests inside an electron microscope; the measured values were found to bẽ 30 GPa and~900 GPa, respectively; and (iv) diverse kinetic processes taking place within the prepared monoatomic BN sheets (so-called "white graphenes") affiliated with intensive knock-on B and N atom displacements under high energy electron beam irradiation in an aberration-corrected medium-voltage high-resolution transmission electron microscope.
Journal of Cell Biology, 2001
Proline-rich tyrosine kinase 2 (PYK2), a tyrosine kinase structurally related to focal adhesion k... more Proline-rich tyrosine kinase 2 (PYK2), a tyrosine kinase structurally related to focal adhesion kinase (FAK), is implicated in regulating cytoskeletal organization. However, mechanisms by which PYK2 participates in and regulates cytoskeletal organization remain largely unknown. Here we report identification of PSGAP, a novel protein that interacts with PYK2 and FAK and contains multiple domains including a pleckstrin homology domain, a rhoGTPase-activating protein domain, and a Src homology 3 domain. PYK2 interacts with PSGAP Src homology 3 domain via the carboxyl-terminal proline-rich sequence. PSGAP is able to increase GTPase activity of CDC42 and RhoA in vitro and in vivo. Remarkably, PYK2, but not FAK, can activate CDC42 via inhibition of PSGAP-mediated GTP hydrolysis of CDC42. Moreover, PSGAP is localized at cell periphery in fibroblasts in a pleckstrin homology domain-dependent manner. Over expression of PSGAP in fibroblasts results in reorganization of cytoskeletal structures and changes of cellular morphology, which requires rhoGTPase-activating activity. Taken together, our results suggest that PSGAP is a signaling protein essential for PYK2 regulation of cytoskeletal organization via Rho family GTPases.
Neuron, 2000
Neuregulins (NRGs) and their receptors, the ErbB protein tyrosine kinases, are essential for neur... more Neuregulins (NRGs) and their receptors, the ErbB protein tyrosine kinases, are essential for neuronal development, but their functions in the adult CNS are unknown. We report that ErbB4 is enriched in the postsynaptic density (PSD) and associates with PSD-95. Heterologous expression of PSD-95 enhanced NRG activation of ErbB4 and MAP kinase. Conversely, inhibiting expression of PSD-95 in neurons attenuated NRG-mediated activation of MAP kinase. PSD-95 formed a ternary complex with two molecules of ErbB4, suggesting that PSD-95 facilitates ErbB4 dimerization. Finally, NRG suppressed induction of long-term potentiation in the hippocampal CA1 region without affecting basal synaptic transmission. Thus, NRG signaling may be synaptic and regulated by PSD-95. A role of NRG signaling in the adult CNS may be modulation of synaptic plasticity.
Applied Mechanics and Materials, 2013
Advanced Functional Materials, 2008
ABSTRACT
Solar Energy Materials and Solar Cells, 2005
Dye sensitized solar cells (DSCs), as a new innovative technology, were developed very quickly in... more Dye sensitized solar cells (DSCs), as a new innovative technology, were developed very quickly in the past decade since Prof. M. Grätzel (EPFL) made the breakthrough in 1991 (Nature 353 (1991) 737). While photoelectric conversion efficiency of 11.04% was achieved last year in EPFL (J. Photocem. Photobiol. A: Chem. 164 (2004) 3), 8.2% was achieved with a size of 2.36 cm2 in 2001 by the ECN group (Sol. Energy Mater. Sol. Cells 84 (2004) 125), which is a very exciting result for large scale DSCs. As potential low cost solar cells, DSC module and the panel's efficiency and stability are still critical problems to the way of marketing. We show our research in the test and design of modules and panels in the past few years at our institute. We have achieved photoelectric conversion efficiency around 6% with 15×20 cm2 module, and our future primary 500 W DSC power station with the same performance 40×60 cm2 panel is under way.
Inorganica Chimica Acta, 2008
To upscale DSC size to commercial size, our group was involved in developing a commercial DSC pan... more To upscale DSC size to commercial size, our group was involved in developing a commercial DSC panel, which could show the industrial way and prospect. The repeatable DSC module with the size of 150 mm · 200 mm and photoelectric conversion efficiency around 6% was reproduced in our laboratory. The DSC panel up to the size of 450 mm · 800 mm was fabricated. This is the high efficiency and industrial production design of a DSC panel, a primary power station with 500 W was installed on our roof for charging the battery. The study on the stability and performance of the DSC module, panel and future production are ongoing in our laboratory. In this article, we will report a systematic study in the test and the design from the single cell, the modules, to the panels, and our design of a 500 W primary DSC power station.
CrystEngComm, 2013
ABSTRACT As a critical issue in “green” synthesis, the mechanism by which the growth temperature ... more ABSTRACT As a critical issue in “green” synthesis, the mechanism by which the growth temperature influences the photoluminescence (PL) properties of quantum dots (QDs) remains unclear. In this work, temperature sensitive growth kinetics and PL evolution of thioglycolic acid (TGA) capped CdS QDs were systematically investigated. This revealed that TGA capped CdS QDs coarsened below and above 90 °C experienced completely different growth kinetics, i.e. a two-stage growth from oriented attachment to Ostwald ripening (OA–OR) and a hybrid growth of the two mechanisms (OA + OR), respectively. With the evolution of the OA–OR growth, the corresponding PL shows characteristics of a gradual weakness of the defect-related emissions centered at 650 nm and a steadily enhanced band-edge emission peaking at 450–470 nm. For the OA + OR hybrid growth, the defect-related emission band steadily coexists with the band-edge emission after an initial decrease. In-depth kinetics and high-resolution transmission electron microscopy (HRTEM) investigation indicate that a low temperature favors a long-term OA self-integration stage, by which internal defects could be relaxed or even eliminated. For a high temperature, this tendency could be greatly inhibited by the concurrent OR growth just around these defects. The FTIR analysis further revealed that the adsorption–desorption equilibrium of capping ligands was temperature-sensitive, resulting in different growth kinetics and PL characteristics of CdS QDs.
Cellulose, 2014
Bacterial cellulose (BC) produced by some microorganisms has been widely accepted as a multifunct... more Bacterial cellulose (BC) produced by some microorganisms has been widely accepted as a multifunctional nano-biomaterial. It is composed of linear glucan molecules attached with hydrogen bonds, which appears similar to plant cellulose. However, when compared with other conventional natural or synthesized counterparts, BC performs better in areas such as biomedicine, functional devices, water treatment, nanofillers, etc. for its distinct superior chemical purity, crystallinity, biocompatibility, and ultrafine network architecture. When BC is incorporated in a material or used as a scaffold, novel features result that are related to BC's intrinsic characteristics mentioned above. This review mainly summarizes the recent developments of the functional products fabricated with BC. Besides, the controllable cultivation conditions should also be discussed for expecting to make a breakthrough in its productivity. We highlight the literatures mainly in last 5 years, exerting ourselves to provide the state-ofthe-art opinions in areas wherever are focused on for BC researching.
Cell, 2001
The Slit protein guides neuronal and leukocyte migration through the transmembrane receptor Round... more The Slit protein guides neuronal and leukocyte migration through the transmembrane receptor Roundabout (Robo). We report here that the intracellular domain of Robo interacts with a novel family of Rho GTPase activating proteins (GAPs). Two of the Slit-Robo GAPs (srGAPs) are expressed in regions responsive to Slit. Slit increased srGAP1-Robo1 interaction and inactivated Cdc42. A dominant negative srGAP1 blocked Slit
Journal of Physical Chemistry B, 2006
Uniform and well-crystallized -Ga 2 O 3 nanowires are prepared by reacting metal Ga with water va... more Uniform and well-crystallized -Ga 2 O 3 nanowires are prepared by reacting metal Ga with water vapor based on the vapor-liquid-solid (VLS) mechanism. Electron microscopy studies show that the nanowires have diameters ranging from 10 to 40 nm and lengths up to tens of micrometers. The contact properties of individual Ga 2 O 3 nanowires with Pt or Au/Ti electrodes are studied, respectively, finding that Pt can form Schottkybarrier junctions and Au/Ti is advantageous to fabricate ohmic contacts with individual Ga 2 O 3 nanowires. In ambient air, the conductivity of the Ga 2 O 3 nanowires is about 1 (Ω‚m) -1 , while with adsorption of NH 3 (or NO 2 ) molecules, the conductivity can increase (or decrease) dramatically at room temperature. The as-grown Ga 2 O 3 nanowires have the properties of an n-type semiconductor.
Nanotechnology - NANOTECHNOL, 2008
Quaternary mixed-valence compound TlIn4S5Cl micro- and nanowires are prepared by partial substitu... more Quaternary mixed-valence compound TlIn4S5Cl micro- and nanowires are prepared by partial substitution of chalcogen with halogen starting from a stoichiometric mixture of TlCl, In and S. Their electrical conductivity and gas sensitivity properties are investigated by using standard four-terminal systems. The specific nanowire resistivity is about 107 Omega cm and corresponds to the value of a typical undoped semiconductor in air. This resistivity is, however, extremely sensitive to NO2 (sensitivity about 150) or NH3, with a rapid response of about 2 s and recovery times. This phenomenon is supposed to be particularly important for future nanodevice applications.
Israel Journal of Chemistry, 2010
Herein the recent experiments performed by the authors on fabricated multi-walled BN nanotubes an... more Herein the recent experiments performed by the authors on fabricated multi-walled BN nanotubes and monoatomic BN graphene-like nanosheets are reviewed. The results are presented in several sections, namely: (i) method for high-yield synthesis of thin, defect-free BN nanotubes of only a few-layers, with external diameters below 10 nm; (ii) verification of BN nanotube piezoelectrical behavior and its electrically-induced thermal decomposition under combined resistive heating and electrical charging in a transmission electron microscope; (iii) the first direct measurements of the true tensile strength and Young's modulus of BN nanotubes, using newly developed nanotensile tests inside an electron microscope; the measured values were found to bẽ 30 GPa and~900 GPa, respectively; and (iv) diverse kinetic processes taking place within the prepared monoatomic BN sheets (so-called "white graphenes") affiliated with intensive knock-on B and N atom displacements under high energy electron beam irradiation in an aberration-corrected medium-voltage high-resolution transmission electron microscope.
Journal of Cell Biology, 2001
Proline-rich tyrosine kinase 2 (PYK2), a tyrosine kinase structurally related to focal adhesion k... more Proline-rich tyrosine kinase 2 (PYK2), a tyrosine kinase structurally related to focal adhesion kinase (FAK), is implicated in regulating cytoskeletal organization. However, mechanisms by which PYK2 participates in and regulates cytoskeletal organization remain largely unknown. Here we report identification of PSGAP, a novel protein that interacts with PYK2 and FAK and contains multiple domains including a pleckstrin homology domain, a rhoGTPase-activating protein domain, and a Src homology 3 domain. PYK2 interacts with PSGAP Src homology 3 domain via the carboxyl-terminal proline-rich sequence. PSGAP is able to increase GTPase activity of CDC42 and RhoA in vitro and in vivo. Remarkably, PYK2, but not FAK, can activate CDC42 via inhibition of PSGAP-mediated GTP hydrolysis of CDC42. Moreover, PSGAP is localized at cell periphery in fibroblasts in a pleckstrin homology domain-dependent manner. Over expression of PSGAP in fibroblasts results in reorganization of cytoskeletal structures and changes of cellular morphology, which requires rhoGTPase-activating activity. Taken together, our results suggest that PSGAP is a signaling protein essential for PYK2 regulation of cytoskeletal organization via Rho family GTPases.
Neuron, 2000
Neuregulins (NRGs) and their receptors, the ErbB protein tyrosine kinases, are essential for neur... more Neuregulins (NRGs) and their receptors, the ErbB protein tyrosine kinases, are essential for neuronal development, but their functions in the adult CNS are unknown. We report that ErbB4 is enriched in the postsynaptic density (PSD) and associates with PSD-95. Heterologous expression of PSD-95 enhanced NRG activation of ErbB4 and MAP kinase. Conversely, inhibiting expression of PSD-95 in neurons attenuated NRG-mediated activation of MAP kinase. PSD-95 formed a ternary complex with two molecules of ErbB4, suggesting that PSD-95 facilitates ErbB4 dimerization. Finally, NRG suppressed induction of long-term potentiation in the hippocampal CA1 region without affecting basal synaptic transmission. Thus, NRG signaling may be synaptic and regulated by PSD-95. A role of NRG signaling in the adult CNS may be modulation of synaptic plasticity.
Applied Mechanics and Materials, 2013
Advanced Functional Materials, 2008
ABSTRACT
Solar Energy Materials and Solar Cells, 2005
Dye sensitized solar cells (DSCs), as a new innovative technology, were developed very quickly in... more Dye sensitized solar cells (DSCs), as a new innovative technology, were developed very quickly in the past decade since Prof. M. Grätzel (EPFL) made the breakthrough in 1991 (Nature 353 (1991) 737). While photoelectric conversion efficiency of 11.04% was achieved last year in EPFL (J. Photocem. Photobiol. A: Chem. 164 (2004) 3), 8.2% was achieved with a size of 2.36 cm2 in 2001 by the ECN group (Sol. Energy Mater. Sol. Cells 84 (2004) 125), which is a very exciting result for large scale DSCs. As potential low cost solar cells, DSC module and the panel's efficiency and stability are still critical problems to the way of marketing. We show our research in the test and design of modules and panels in the past few years at our institute. We have achieved photoelectric conversion efficiency around 6% with 15×20 cm2 module, and our future primary 500 W DSC power station with the same performance 40×60 cm2 panel is under way.
Inorganica Chimica Acta, 2008
To upscale DSC size to commercial size, our group was involved in developing a commercial DSC pan... more To upscale DSC size to commercial size, our group was involved in developing a commercial DSC panel, which could show the industrial way and prospect. The repeatable DSC module with the size of 150 mm · 200 mm and photoelectric conversion efficiency around 6% was reproduced in our laboratory. The DSC panel up to the size of 450 mm · 800 mm was fabricated. This is the high efficiency and industrial production design of a DSC panel, a primary power station with 500 W was installed on our roof for charging the battery. The study on the stability and performance of the DSC module, panel and future production are ongoing in our laboratory. In this article, we will report a systematic study in the test and the design from the single cell, the modules, to the panels, and our design of a 500 W primary DSC power station.
CrystEngComm, 2013
ABSTRACT As a critical issue in “green” synthesis, the mechanism by which the growth temperature ... more ABSTRACT As a critical issue in “green” synthesis, the mechanism by which the growth temperature influences the photoluminescence (PL) properties of quantum dots (QDs) remains unclear. In this work, temperature sensitive growth kinetics and PL evolution of thioglycolic acid (TGA) capped CdS QDs were systematically investigated. This revealed that TGA capped CdS QDs coarsened below and above 90 °C experienced completely different growth kinetics, i.e. a two-stage growth from oriented attachment to Ostwald ripening (OA–OR) and a hybrid growth of the two mechanisms (OA + OR), respectively. With the evolution of the OA–OR growth, the corresponding PL shows characteristics of a gradual weakness of the defect-related emissions centered at 650 nm and a steadily enhanced band-edge emission peaking at 450–470 nm. For the OA + OR hybrid growth, the defect-related emission band steadily coexists with the band-edge emission after an initial decrease. In-depth kinetics and high-resolution transmission electron microscopy (HRTEM) investigation indicate that a low temperature favors a long-term OA self-integration stage, by which internal defects could be relaxed or even eliminated. For a high temperature, this tendency could be greatly inhibited by the concurrent OR growth just around these defects. The FTIR analysis further revealed that the adsorption–desorption equilibrium of capping ligands was temperature-sensitive, resulting in different growth kinetics and PL characteristics of CdS QDs.