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Papers by zaki Noah hasan

Iraqi journal of medical sciences, 2014

Background Guillain Barré syndrome (GBS) is an acute post infective autoimmune polyradiculo-neuro... more Background Guillain Barré syndrome (GBS) is an acute post infective autoimmune polyradiculo-neuropathy; it is the commonest polyneuropathy causing respiratory failure. A lot of studies suggested certain GBS clinical and preclinical features anticipate and predicate the neuromuscular respiratory failure and can accurately assess the progression to mechanical ventilation; bulbar muscles involvement, severity of weakness of upper and lower limbs, bilateral facial muscles involvement and autonomic nervous system involvement were the main features associated with progression to mechanical ventilation. Objectives To assess demographic, clinical and para clinical features and their relation with the progression of GBS to respiratory failure. Methods Clinical and paraclinical predictors of impending respiratory involvement and requirement for mechanical ventilation were studied in 40 GBS patients aged 12-57 years (28 males and 12 females). Results Ten (6 female/4 male) patients (25%) were admitted to the intensive care unit and received mechanical ventilation. Younger age, female gender and rapid disease progression in first 3 days were associated with respiratory involvement and subsequent ventilation. Bulbar weakness, bilateral facial palsy, poor digit counting (<10/1 breath) were the strongest indicators of impending respiratory failure. In combination they were found in 90% of ventilated patients. Dense weakness (power grade ≤2), weak neck flexion and axonal electromyography also showed significant risk for mechanical ventilation. Other parameters (autonomic dysfunction, antecedent gastrointestinal and respiratory illness, earlier upper limbs weakness and pain) showed no statistical significance in our study Conclusion Respiratory failure in the course of GBS can to some extent, predicted depending on clinical information. Respiratory failure was associated with younger age, female gender, rapid progressive weakness, bulbar weakness. Facial weakness. Dense weakness, weak neck flexion, poor digit count and axonal neuropathy.

License, which permits unrestricted use, distribution, and reproduction in any medium, provided t... more License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. To assess differences in age of onset, hypertension duration, type of drug, treatment compliance, and salt-free diet compliance between patients with stroke and myocardial infarction. Patients and Methods. The study was conducted in 3 hospitals in Baghdad between June 2010 and June 2011. First group includes 81 stroke patients (36 females and 45 males), age ranges between (33–82 years). Second group includes 110 myocardial infarction patients (46 females and 64 males), ages ranges from (23– 76 years). Results. Salt-free diet noncompliance was seen in 69 % and 62 % of Myocardial infarction and stroke groups, respectively. Silent hypertension was seen in 6.3 % and 19.7 % of myocardial infarction and stroke groups, respectively. Noncompliant on antihypertensive therapy was seen in 61%, 71%, and 48 % of the total, myocardial infarction, and stro...

American Journal of Internal Medicine, 2015

Background: Stroke is the most common causes of seizures in adulthood. The incidence of seizures ... more Background: Stroke is the most common causes of seizures in adulthood. The incidence of seizures after stroke varies widely between 3.7% to 42.8%. Objectives: To assess the incidence of post-stroke seizures, the time of onset of seizures and, the type of seizures, also to evaluate the relationship between the development of seizures with subtypes of stroke, stroke size, and stroke site. Patients and methods: Data of 380stroke patients were collected consecutively in Baghdad Teaching Hospital from Oct. 2013 to Nov. 2014; age, sex, date of stroke, symptoms and signs of stroke, time of seizures onset, patterns of seizures, neuroimaging findings, and the findings of both carotid Doppler and echocardiography were studied in both ischemic and hemorrhagic stroke.. Statistical analyses were performed using the SPSS software package for Windows 6.0. Results: Post-stroke seizures were developed in (9.73%) of our patients, furthermore, (8.5%) of patients with ischemic stroke and (18%) of patients with hemorrhagic stroke developed seizures. early onset seizures occurred in (56.76%) of patients with post-stroke seizures, while (71.43%) developed seizures within the first 24 hours. status epilepticus was seen in (10.8%). partial seizures developed in (61.9%) of patients with early onset seizures, while, (75%) of patients with late onset seizures had Secondarily generalized seizures. post-stroke seizures were occurred in (81.1%) of patients with cortical lesions, (P< 0.00005). Also (20%) of patients with large size lesion developed seizures, while (5.3%) of patients with small lesion developed seizures, (P < 0.0002). Post-stroke seizures developed in; (17.53%), (6.06%), (1.47%), of patients with embolic, thrombotic, and lacunar subtype of stroke, (P = 0.0004). Conclusions: The post-hemorrhagic stroke seizures more frequently within the first 24hr after the onset of stroke, while the post-ischemic stroke seizures occur equally at early onset and at late onset seizures, early onset seizures are more likely to be simple partial seizures, while late onset seizures are more likely to be secondarily generalized, further more status epilepticus occur more frequently within the first week after the onset of stroke. The hemorrhagic stroke, the embolic stroke, the cortical lesion and the large size lesion are associated with a higher risk for the development of the post-stroke seizures.

British Journal of Medicine and Medical Research, 2015

Abstract Background:Refractory epilepsy patients who fail to respond to two antiepileptic drugs u... more Abstract Background:Refractory epilepsy patients who fail to respond to two antiepileptic drugs used appropriately are likely to have medically refractory seizure disorder and should be investigated for alternative forms of treatments like experimental drug trial, surgical treatment, electrical stimulation and combination of these. Vagal nerve stimulation is an adjunctive treatment for certain types of epilepsy. Objectives:To evaluate the efficacy of vagal nerve stimulation in refractory epilepsy, as an adjunctive therapy to antiepileptic drugs in Iraqi patients. Methods:A retrospective study recruiting 34 patients at Neurosciences Hospital in Iraq between Feb. 2008 and Jan. 2011. Diagnosed as refractory epilepsy according to International League Against Epilepsy criteria; the epilepsy state, number of the anti-epileptic drugs, frequency and severity of the attacks (using Chalfont scale) was assessed before and after the vagal nerve stimulation implantation. Programming was done eve...

Background Carpal tunnel syndrome (CTS) is the most common nerve entrapment, electrodiagnostic st... more Background Carpal tunnel syndrome (CTS) is the most common nerve entrapment, electrodiagnostic studies are a

Background Parkinson's disease (PD) is the second most common degenerative neurologic disorde... more Background Parkinson's disease (PD) is the second most common degenerative neurologic disorder after Alzheimer's

Neurosciences (Riyadh, Saudi Arabia), 2013

Clinical features and surgical outcomes of cerebral hydatid disease were recently discussed by Ha... more Clinical features and surgical outcomes of cerebral hydatid disease were recently discussed by Hasan et al. 1 In their case series, they introduced bypassing the liver as the route of pulmonary involvement. 1 However, 2 other distinct pathways have also been introduced for pulmonary hydatidosis; lymphatic spread via the thoracic duct into the right heart and ultimately to the pulmonary parenchyma, and direct pulmonary exposure from inhalation of eggs. Indeed, the former is considered a major pathway for the larvae to bypass the hepatic sinusoidal system, raising the probability of cerebral involvement. 2,3 The diagnosis of hydatid disease is based on several modalities among which non-invasive imaging and serological tests are of high value. 4 Serodiagnostic tests are frequently used for the preoperative diagnosis of extrahepatic hydatid disease, despite not being as sensitive as for liver hydatosis. 5 Nonetheless, eosinophilia in the peripheral blood is usually informative. 6 This diagnostic criterion seems to have been overlooked by Hasan et al.

Neurosciences (Riyadh, Saudi Arabia), 2013

IRAQI JOURNAL OF …, 2000

... among hospitalized patients with ischemic stroke in Baghdad Zaki Noah Hasan1 FICMS, Hasan Aze... more ... among hospitalized patients with ischemic stroke in Baghdad Zaki Noah Hasan1 FICMS, Hasan Azeez Hasan 2 FICMS, Hamed Facker Mukhelif3 ... 1), this increase with increasing age is in agreement to Suleiman, Khalil and Almehedawi study [12], Abu-nayla-Salman study [13 ...

World Journal of Neuroscience, 2016

Patients presented with spinal metastases from unknown primary tumours are rare. In this research... more Patients presented with spinal metastases from unknown primary tumours are rare. In this research we evaluated all patients with metastatic spinal tumour of unknown primary tumour, all patients were evaluated pre-operatively and comparison was done to those patients who had known primary tumour the study aimed to compare the group with known primary and the group with the unknown primary regarding the: mean age, gender, duration of symptoms, complication rate, region of the spine affected by metastasis, presence or absence of other skeletal or visceral metastasis, histological cell type and neurological outcome. Method: A retrospective study was performed on 40 patients presented to Neuroscience hospital in Baghdad from January 2010 till January 2014; all patients with metastatic spinal tumour were included in our study. We reviewed all patients' records including age, sex, primary tumour, duration of their symptoms, neurological out come and complications. Results: Out of the 40 patient who presented with spinal tumours that underwent surgery duo to metastatic spinal tumour, five patients presented with spinal compression duo to metastatic tumour of unknown primary tumour (12.5%). The mean age was 64 years, 4 male and one female. For those with a known primary tumour mean age was 61 year, 22 male 13 female. Duration of symptoms prior to surgery was the same 180 days for those with unknown primary and 190 day for those with known primary tumours. They also had similar neurological outcome (80%) remain the same or improved post operatively for those with unknown primary and (85.7%) for those with a known primary tumour, and a similar complication rate for unknown primary was 25% versus 28% for known. The primary site of metastatic spinal tumour of unknown primary was confirmed after histopathology all shown adenocarcinoma four from the lung (80%) and one from colorectal. While the most common known carcinoma site were the lung 18 patient (51.4%), colorectal 8 (22.8%), breast 7 (20%), and renal 2 (5.71%). All patient who complain from secondary spinal metastasis with unknown primary tumour didn't show any other * Corresponding author. W. J. Sagban et al. 19 skeletal or visceral metastasis, while those with a known primary tumour 6 patient out of 35 (17.1%) shown involvement of other site, the indication of surgery was to remove cord compression and restore neurological deficit. The most common site for metastasis was the dorsal spine for those of an unknown primary tumour 4 out of 5 patients (80%), and for those of a known primary tumour it was the lumbar area 28 out of 35 patient (80%). In conclusion metastatic spinal tumour of unknown primary was a common condition; it has similar demographic features, complications, and neurologic sequel with the spinal metastasis of known primary. Adenocarcinoma of the lung is the most common primary tumour proved after histopathology for spinal metastasis of unknown primary.

<i>Abstract</i><br>The Guillain-Barré syndrome (GBS) is an acute post-infective... more <i>Abstract</i><br>The Guillain-Barré syndrome (GBS) is an acute post-infective autoimmune polyradiculoneuropathy, it is the commonest peripheral neuropathy causing respiratory failure. The aim of the study is to use the New Combined Scoring System in anticipating respiratory failure in order to perform elective measures without waiting for emergency situations to occur.Patients and methods: Fifty patients with GBS were studied. Eight clinical parameters (including progression of patients to maximum weakness, respiratory rate/minute, breath holding count (the number of digits the patient can count in holding his breath), presence of facial muscle weakness (unilateral or bilateral), presence of weakness of the bulbar muscle, weakness of the neck flexor muscle, and limbs weakness) were assessed for each patient and a certain score was given to each parameter, a designed combined score being constructed by taking into consideration all the above mentioned clinical parameters. Results and discussion: Fifteen patients (30%) that were enrolled in our study developed respiratory failure. There was a highly significant statistical association between the development of respiratory failure and the lower grades of (bulbar muscle weakness score, breath holding count scores, neck muscle weakness score, lower limbs and upper limbs weakness score , respiratory rate score) and the total sum score above 16 out of 30 (p-value=0.000) . No significant statistical difference was found regarding the progression to maximum weakness (p-value=0.675) and facial muscle weakness (p-value=0.482).Conclusion: The patients who obtained a combined score (above 16'30) are at great risk of having respiratory failure.<br><b><br></b><b>Find more at:</b><b>https://www.edusoft.ro/brain/index.php/brain/article/view/145</b><br&gt;

Background: The Guillain-Barré syndrome (GBS) is an acute post-infective autoimmune polyradiculon... more Background: The Guillain-Barré syndrome (GBS) is an acute post-infective autoimmune polyradiculoneuropathy, it is the commonest peripheral neuropathy causing respiratory failure. The aim of the study is to use the New Combined Scoring System in anticipating respiratory failure in order to perform elective measures without waiting for emergency situations to occur. Patients and methods: Fifty patients with GBS were studied. Eight clinical parameters (including progression of patients to maximum weakness, respiratory rate/minute, breath holding count (the number of digits the patient can count in holding his breath), presence of facial muscle weakness (unilateral or bilateral), presence of weakness of the bulbar muscle, weakness of the neck flexor muscle, and limbs weakness) were assessed for each patient and a certain score was given to each parameter, a designed combined score being constructed by taking into consideration all the above mentioned clinical parameters. Results and dis...

In order to obtain the range of scores that represent 95% of the observations that ended in respi... more In order to obtain the range of scores that represent 95% of the observations that ended in respiratory failure, we used the frequency distribution curve (fig 9) with (2SD) above and below the calculated mean. This gives a value of (16-24) as the limits of interval including the score of patients at risk of developing respiratory failure

Medical Journal of Babylon, 2015

AL-Kindy College Medical Journal, 2019

Background: Friedreich ataxia (FRDA) is the most common form of inherited ataxia, comprising one-... more Background: Friedreich ataxia (FRDA) is the most common form of inherited ataxia, comprising one-half of all hereditary ataxias with a carrier rate between 1 in 60 to 1 in 90 and with a disease prevalence of 1 per 29,000. It can occur in two forms the classic form or in association with a vitamin E dependent ataxia. The precise role of Vitamin E in the nervous system is unknown; An Oxidative attack is suspected to play a role in Ataxia with Vitamin E deficiency, as well as in Friedreich ataxia. Vitamin E is the major free-radical-trapping antioxidant. Objective: Theobjectives of the study is to asses vitamin E level in patients with Friedreichs ataxia phenotype in Iraqi patients. Type of the study:Cross-sectional study. Method: This study was conducted at the neuroscience hospital and Baghdad teaching hospital during the period from the 1st of November 2013 through November 2014. Forty patients with friedreich's ataxia attended in neuroscience hospital and Baghdad teaching hospi...

AL-Kindy College Medical Journal, 2019

Background: Drug resistant epilepsy is defined as failure of adequate trials of two tolerated, ap... more Background: Drug resistant epilepsy is defined as failure of adequate trials of two tolerated, appropriately chosen and used antiepileptic drug schedules to achieve sustained seizure freedom. Up to 30% of patients referred to clinics with a diagnosis of pharmaco-resistant epilepsy may have been misdiagnosed, and many can be helped by optimizing their treatment.Pseudoresistance, in which seizures persist because the underlying disorder has not been adequately or appropriately treated, must be ruled out or corrected before drug treatment can be considered to have failed. Objectives: The objectives of this study were to determine the causes of drug failure in patients with epilepsy and to differentiate between drug resistant epilepsy and pseudoresistant epilepsy. Type of the study: This is a retrospective study. Method: It is conducted in Baghdad governorate at the epilepsy clinic in the neurosciences hospital during the period from the 1st of February through July 2013. Two hundred pa...

AL-Kindy College Medical Journal, 2019

Background: Multiple sclerosis is a chronic heterogeneous demyelinating axonal and inflammatory d... more Background: Multiple sclerosis is a chronic heterogeneous demyelinating axonal and inflammatory disease involving the Central Nervous System [CNS] white matter with a possibility of gray matter involvement in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This damage disrupts the ability of parts of the nervous system to communicate, resulting in a wide range of signs and symptoms. Cerebral venous insufficiency theory was raised as a possible etiology for the disease at 2008 by Zamboni an Italian cardiothoracic surgeon. This theory was defeated by Multiple Sclerosis[ MS] researchers and scientists who thought that the disease is an autoimmune rather than vascular. Objective: To assess the findings of Magnetic Resonance Venography [MRV] in a group of patients with MS and to compare these results with a healthy control group Magnetic Resonance Venography[ MRV] findings. Type of the study: A case – control cross sectional study. Methods: it was con...

AL-Kindy College Medical Journal, 2017

Background:Parkinson’disease(PD) is a neurodegenerative disorder of the central nervous system ch... more Background:Parkinson’disease(PD) is a neurodegenerative disorder of the central nervous system characterized by resting tremor, bradykinesia, cogwheel rigidity, and impairment of postural reflexes; the frequency of PD increases with aging.Clinically Parkinson's disease characterized by two groups of symptoms: motor and non-motor symptoms.Non-motor symptoms can be categorized as autonomic, cognitive/psychiatric (may include depression, dementia, anxiety, hallucinations), sensory and rapid eye movements (REM) sleep behavior disorder (RBD). Objectives:The objectives of this study are to find out the frequency of the non-motor symptoms of idiopathic Parkinson disease in a group of patients in Baghdad hospitals. Type of the study:A cross sectional study with analytic elements, Methods: It was conducted in movement disorders clinic in neuroscience hospital, outpatient clinic at Baghdad teaching hospital and AL-Kadhumain teaching hospital during the period between the 1st. of December ...

Indian journal of dermatology, venereology and leprology

HLA-DRB1*04, -DRB1*08, -DRB1*14, -DQB1*03 and -DQB1*05 are reported to have significant associati... more HLA-DRB1*04, -DRB1*08, -DRB1*14, -DQB1*03 and -DQB1*05 are reported to have significant association with pemphigus vulgaris; however, this is partially dependent on ethnicity. This study was done to determine the HLA-DR and -DQ types prevalent in Indian patients with pemphigus vulgaris. A prospective case-control study was done for a period of 9 months in Christian Medical College Vellore, India. HLA typing was done by PCR-SSOP method in 50 cases and 50 healthy controls. Allele frequencies in cases and controls were compared and odds ratios with 95% confidence interval were calculated. The mean age of the patients (29 females, 21 males) and that of controls (36 males, 14 females) were 41.3 ± 13.65 and 35.42 ± 11.09 years, respectively. HLA-DRB1*14 was present in 47 patients and 18 controls (OR, 27.85; 95% CI, 7.57-102.42) and HLA-DQB1*05 was seen in 47 patients and 24 controls (OR, 16.97; 95% CI, 4.66-61.80). The haplotype DRB1*14, DQB1*05 was present in 44 patients and 14 controls ...

Iraqi journal of medical sciences, 2014

Background Guillain Barré syndrome (GBS) is an acute post infective autoimmune polyradiculo-neuro... more Background Guillain Barré syndrome (GBS) is an acute post infective autoimmune polyradiculo-neuropathy; it is the commonest polyneuropathy causing respiratory failure. A lot of studies suggested certain GBS clinical and preclinical features anticipate and predicate the neuromuscular respiratory failure and can accurately assess the progression to mechanical ventilation; bulbar muscles involvement, severity of weakness of upper and lower limbs, bilateral facial muscles involvement and autonomic nervous system involvement were the main features associated with progression to mechanical ventilation. Objectives To assess demographic, clinical and para clinical features and their relation with the progression of GBS to respiratory failure. Methods Clinical and paraclinical predictors of impending respiratory involvement and requirement for mechanical ventilation were studied in 40 GBS patients aged 12-57 years (28 males and 12 females). Results Ten (6 female/4 male) patients (25%) were admitted to the intensive care unit and received mechanical ventilation. Younger age, female gender and rapid disease progression in first 3 days were associated with respiratory involvement and subsequent ventilation. Bulbar weakness, bilateral facial palsy, poor digit counting (<10/1 breath) were the strongest indicators of impending respiratory failure. In combination they were found in 90% of ventilated patients. Dense weakness (power grade ≤2), weak neck flexion and axonal electromyography also showed significant risk for mechanical ventilation. Other parameters (autonomic dysfunction, antecedent gastrointestinal and respiratory illness, earlier upper limbs weakness and pain) showed no statistical significance in our study Conclusion Respiratory failure in the course of GBS can to some extent, predicted depending on clinical information. Respiratory failure was associated with younger age, female gender, rapid progressive weakness, bulbar weakness. Facial weakness. Dense weakness, weak neck flexion, poor digit count and axonal neuropathy.

License, which permits unrestricted use, distribution, and reproduction in any medium, provided t... more License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. To assess differences in age of onset, hypertension duration, type of drug, treatment compliance, and salt-free diet compliance between patients with stroke and myocardial infarction. Patients and Methods. The study was conducted in 3 hospitals in Baghdad between June 2010 and June 2011. First group includes 81 stroke patients (36 females and 45 males), age ranges between (33–82 years). Second group includes 110 myocardial infarction patients (46 females and 64 males), ages ranges from (23– 76 years). Results. Salt-free diet noncompliance was seen in 69 % and 62 % of Myocardial infarction and stroke groups, respectively. Silent hypertension was seen in 6.3 % and 19.7 % of myocardial infarction and stroke groups, respectively. Noncompliant on antihypertensive therapy was seen in 61%, 71%, and 48 % of the total, myocardial infarction, and stro...

American Journal of Internal Medicine, 2015

Background: Stroke is the most common causes of seizures in adulthood. The incidence of seizures ... more Background: Stroke is the most common causes of seizures in adulthood. The incidence of seizures after stroke varies widely between 3.7% to 42.8%. Objectives: To assess the incidence of post-stroke seizures, the time of onset of seizures and, the type of seizures, also to evaluate the relationship between the development of seizures with subtypes of stroke, stroke size, and stroke site. Patients and methods: Data of 380stroke patients were collected consecutively in Baghdad Teaching Hospital from Oct. 2013 to Nov. 2014; age, sex, date of stroke, symptoms and signs of stroke, time of seizures onset, patterns of seizures, neuroimaging findings, and the findings of both carotid Doppler and echocardiography were studied in both ischemic and hemorrhagic stroke.. Statistical analyses were performed using the SPSS software package for Windows 6.0. Results: Post-stroke seizures were developed in (9.73%) of our patients, furthermore, (8.5%) of patients with ischemic stroke and (18%) of patients with hemorrhagic stroke developed seizures. early onset seizures occurred in (56.76%) of patients with post-stroke seizures, while (71.43%) developed seizures within the first 24 hours. status epilepticus was seen in (10.8%). partial seizures developed in (61.9%) of patients with early onset seizures, while, (75%) of patients with late onset seizures had Secondarily generalized seizures. post-stroke seizures were occurred in (81.1%) of patients with cortical lesions, (P< 0.00005). Also (20%) of patients with large size lesion developed seizures, while (5.3%) of patients with small lesion developed seizures, (P < 0.0002). Post-stroke seizures developed in; (17.53%), (6.06%), (1.47%), of patients with embolic, thrombotic, and lacunar subtype of stroke, (P = 0.0004). Conclusions: The post-hemorrhagic stroke seizures more frequently within the first 24hr after the onset of stroke, while the post-ischemic stroke seizures occur equally at early onset and at late onset seizures, early onset seizures are more likely to be simple partial seizures, while late onset seizures are more likely to be secondarily generalized, further more status epilepticus occur more frequently within the first week after the onset of stroke. The hemorrhagic stroke, the embolic stroke, the cortical lesion and the large size lesion are associated with a higher risk for the development of the post-stroke seizures.

British Journal of Medicine and Medical Research, 2015

Abstract Background:Refractory epilepsy patients who fail to respond to two antiepileptic drugs u... more Abstract Background:Refractory epilepsy patients who fail to respond to two antiepileptic drugs used appropriately are likely to have medically refractory seizure disorder and should be investigated for alternative forms of treatments like experimental drug trial, surgical treatment, electrical stimulation and combination of these. Vagal nerve stimulation is an adjunctive treatment for certain types of epilepsy. Objectives:To evaluate the efficacy of vagal nerve stimulation in refractory epilepsy, as an adjunctive therapy to antiepileptic drugs in Iraqi patients. Methods:A retrospective study recruiting 34 patients at Neurosciences Hospital in Iraq between Feb. 2008 and Jan. 2011. Diagnosed as refractory epilepsy according to International League Against Epilepsy criteria; the epilepsy state, number of the anti-epileptic drugs, frequency and severity of the attacks (using Chalfont scale) was assessed before and after the vagal nerve stimulation implantation. Programming was done eve...

Background Carpal tunnel syndrome (CTS) is the most common nerve entrapment, electrodiagnostic st... more Background Carpal tunnel syndrome (CTS) is the most common nerve entrapment, electrodiagnostic studies are a

Background Parkinson's disease (PD) is the second most common degenerative neurologic disorde... more Background Parkinson's disease (PD) is the second most common degenerative neurologic disorder after Alzheimer's

Neurosciences (Riyadh, Saudi Arabia), 2013

Clinical features and surgical outcomes of cerebral hydatid disease were recently discussed by Ha... more Clinical features and surgical outcomes of cerebral hydatid disease were recently discussed by Hasan et al. 1 In their case series, they introduced bypassing the liver as the route of pulmonary involvement. 1 However, 2 other distinct pathways have also been introduced for pulmonary hydatidosis; lymphatic spread via the thoracic duct into the right heart and ultimately to the pulmonary parenchyma, and direct pulmonary exposure from inhalation of eggs. Indeed, the former is considered a major pathway for the larvae to bypass the hepatic sinusoidal system, raising the probability of cerebral involvement. 2,3 The diagnosis of hydatid disease is based on several modalities among which non-invasive imaging and serological tests are of high value. 4 Serodiagnostic tests are frequently used for the preoperative diagnosis of extrahepatic hydatid disease, despite not being as sensitive as for liver hydatosis. 5 Nonetheless, eosinophilia in the peripheral blood is usually informative. 6 This diagnostic criterion seems to have been overlooked by Hasan et al.

Neurosciences (Riyadh, Saudi Arabia), 2013

IRAQI JOURNAL OF …, 2000

... among hospitalized patients with ischemic stroke in Baghdad Zaki Noah Hasan1 FICMS, Hasan Aze... more ... among hospitalized patients with ischemic stroke in Baghdad Zaki Noah Hasan1 FICMS, Hasan Azeez Hasan 2 FICMS, Hamed Facker Mukhelif3 ... 1), this increase with increasing age is in agreement to Suleiman, Khalil and Almehedawi study [12], Abu-nayla-Salman study [13 ...

World Journal of Neuroscience, 2016

Patients presented with spinal metastases from unknown primary tumours are rare. In this research... more Patients presented with spinal metastases from unknown primary tumours are rare. In this research we evaluated all patients with metastatic spinal tumour of unknown primary tumour, all patients were evaluated pre-operatively and comparison was done to those patients who had known primary tumour the study aimed to compare the group with known primary and the group with the unknown primary regarding the: mean age, gender, duration of symptoms, complication rate, region of the spine affected by metastasis, presence or absence of other skeletal or visceral metastasis, histological cell type and neurological outcome. Method: A retrospective study was performed on 40 patients presented to Neuroscience hospital in Baghdad from January 2010 till January 2014; all patients with metastatic spinal tumour were included in our study. We reviewed all patients' records including age, sex, primary tumour, duration of their symptoms, neurological out come and complications. Results: Out of the 40 patient who presented with spinal tumours that underwent surgery duo to metastatic spinal tumour, five patients presented with spinal compression duo to metastatic tumour of unknown primary tumour (12.5%). The mean age was 64 years, 4 male and one female. For those with a known primary tumour mean age was 61 year, 22 male 13 female. Duration of symptoms prior to surgery was the same 180 days for those with unknown primary and 190 day for those with known primary tumours. They also had similar neurological outcome (80%) remain the same or improved post operatively for those with unknown primary and (85.7%) for those with a known primary tumour, and a similar complication rate for unknown primary was 25% versus 28% for known. The primary site of metastatic spinal tumour of unknown primary was confirmed after histopathology all shown adenocarcinoma four from the lung (80%) and one from colorectal. While the most common known carcinoma site were the lung 18 patient (51.4%), colorectal 8 (22.8%), breast 7 (20%), and renal 2 (5.71%). All patient who complain from secondary spinal metastasis with unknown primary tumour didn't show any other * Corresponding author. W. J. Sagban et al. 19 skeletal or visceral metastasis, while those with a known primary tumour 6 patient out of 35 (17.1%) shown involvement of other site, the indication of surgery was to remove cord compression and restore neurological deficit. The most common site for metastasis was the dorsal spine for those of an unknown primary tumour 4 out of 5 patients (80%), and for those of a known primary tumour it was the lumbar area 28 out of 35 patient (80%). In conclusion metastatic spinal tumour of unknown primary was a common condition; it has similar demographic features, complications, and neurologic sequel with the spinal metastasis of known primary. Adenocarcinoma of the lung is the most common primary tumour proved after histopathology for spinal metastasis of unknown primary.

<i>Abstract</i><br>The Guillain-Barré syndrome (GBS) is an acute post-infective... more <i>Abstract</i><br>The Guillain-Barré syndrome (GBS) is an acute post-infective autoimmune polyradiculoneuropathy, it is the commonest peripheral neuropathy causing respiratory failure. The aim of the study is to use the New Combined Scoring System in anticipating respiratory failure in order to perform elective measures without waiting for emergency situations to occur.Patients and methods: Fifty patients with GBS were studied. Eight clinical parameters (including progression of patients to maximum weakness, respiratory rate/minute, breath holding count (the number of digits the patient can count in holding his breath), presence of facial muscle weakness (unilateral or bilateral), presence of weakness of the bulbar muscle, weakness of the neck flexor muscle, and limbs weakness) were assessed for each patient and a certain score was given to each parameter, a designed combined score being constructed by taking into consideration all the above mentioned clinical parameters. Results and discussion: Fifteen patients (30%) that were enrolled in our study developed respiratory failure. There was a highly significant statistical association between the development of respiratory failure and the lower grades of (bulbar muscle weakness score, breath holding count scores, neck muscle weakness score, lower limbs and upper limbs weakness score , respiratory rate score) and the total sum score above 16 out of 30 (p-value=0.000) . No significant statistical difference was found regarding the progression to maximum weakness (p-value=0.675) and facial muscle weakness (p-value=0.482).Conclusion: The patients who obtained a combined score (above 16'30) are at great risk of having respiratory failure.<br><b><br></b><b>Find more at:</b><b>https://www.edusoft.ro/brain/index.php/brain/article/view/145</b><br&gt;

Background: The Guillain-Barré syndrome (GBS) is an acute post-infective autoimmune polyradiculon... more Background: The Guillain-Barré syndrome (GBS) is an acute post-infective autoimmune polyradiculoneuropathy, it is the commonest peripheral neuropathy causing respiratory failure. The aim of the study is to use the New Combined Scoring System in anticipating respiratory failure in order to perform elective measures without waiting for emergency situations to occur. Patients and methods: Fifty patients with GBS were studied. Eight clinical parameters (including progression of patients to maximum weakness, respiratory rate/minute, breath holding count (the number of digits the patient can count in holding his breath), presence of facial muscle weakness (unilateral or bilateral), presence of weakness of the bulbar muscle, weakness of the neck flexor muscle, and limbs weakness) were assessed for each patient and a certain score was given to each parameter, a designed combined score being constructed by taking into consideration all the above mentioned clinical parameters. Results and dis...

In order to obtain the range of scores that represent 95% of the observations that ended in respi... more In order to obtain the range of scores that represent 95% of the observations that ended in respiratory failure, we used the frequency distribution curve (fig 9) with (2SD) above and below the calculated mean. This gives a value of (16-24) as the limits of interval including the score of patients at risk of developing respiratory failure

Medical Journal of Babylon, 2015

AL-Kindy College Medical Journal, 2019

Background: Friedreich ataxia (FRDA) is the most common form of inherited ataxia, comprising one-... more Background: Friedreich ataxia (FRDA) is the most common form of inherited ataxia, comprising one-half of all hereditary ataxias with a carrier rate between 1 in 60 to 1 in 90 and with a disease prevalence of 1 per 29,000. It can occur in two forms the classic form or in association with a vitamin E dependent ataxia. The precise role of Vitamin E in the nervous system is unknown; An Oxidative attack is suspected to play a role in Ataxia with Vitamin E deficiency, as well as in Friedreich ataxia. Vitamin E is the major free-radical-trapping antioxidant. Objective: Theobjectives of the study is to asses vitamin E level in patients with Friedreichs ataxia phenotype in Iraqi patients. Type of the study:Cross-sectional study. Method: This study was conducted at the neuroscience hospital and Baghdad teaching hospital during the period from the 1st of November 2013 through November 2014. Forty patients with friedreich's ataxia attended in neuroscience hospital and Baghdad teaching hospi...

AL-Kindy College Medical Journal, 2019

Background: Drug resistant epilepsy is defined as failure of adequate trials of two tolerated, ap... more Background: Drug resistant epilepsy is defined as failure of adequate trials of two tolerated, appropriately chosen and used antiepileptic drug schedules to achieve sustained seizure freedom. Up to 30% of patients referred to clinics with a diagnosis of pharmaco-resistant epilepsy may have been misdiagnosed, and many can be helped by optimizing their treatment.Pseudoresistance, in which seizures persist because the underlying disorder has not been adequately or appropriately treated, must be ruled out or corrected before drug treatment can be considered to have failed. Objectives: The objectives of this study were to determine the causes of drug failure in patients with epilepsy and to differentiate between drug resistant epilepsy and pseudoresistant epilepsy. Type of the study: This is a retrospective study. Method: It is conducted in Baghdad governorate at the epilepsy clinic in the neurosciences hospital during the period from the 1st of February through July 2013. Two hundred pa...

AL-Kindy College Medical Journal, 2019

Background: Multiple sclerosis is a chronic heterogeneous demyelinating axonal and inflammatory d... more Background: Multiple sclerosis is a chronic heterogeneous demyelinating axonal and inflammatory disease involving the Central Nervous System [CNS] white matter with a possibility of gray matter involvement in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This damage disrupts the ability of parts of the nervous system to communicate, resulting in a wide range of signs and symptoms. Cerebral venous insufficiency theory was raised as a possible etiology for the disease at 2008 by Zamboni an Italian cardiothoracic surgeon. This theory was defeated by Multiple Sclerosis[ MS] researchers and scientists who thought that the disease is an autoimmune rather than vascular. Objective: To assess the findings of Magnetic Resonance Venography [MRV] in a group of patients with MS and to compare these results with a healthy control group Magnetic Resonance Venography[ MRV] findings. Type of the study: A case – control cross sectional study. Methods: it was con...

AL-Kindy College Medical Journal, 2017

Background:Parkinson’disease(PD) is a neurodegenerative disorder of the central nervous system ch... more Background:Parkinson’disease(PD) is a neurodegenerative disorder of the central nervous system characterized by resting tremor, bradykinesia, cogwheel rigidity, and impairment of postural reflexes; the frequency of PD increases with aging.Clinically Parkinson's disease characterized by two groups of symptoms: motor and non-motor symptoms.Non-motor symptoms can be categorized as autonomic, cognitive/psychiatric (may include depression, dementia, anxiety, hallucinations), sensory and rapid eye movements (REM) sleep behavior disorder (RBD). Objectives:The objectives of this study are to find out the frequency of the non-motor symptoms of idiopathic Parkinson disease in a group of patients in Baghdad hospitals. Type of the study:A cross sectional study with analytic elements, Methods: It was conducted in movement disorders clinic in neuroscience hospital, outpatient clinic at Baghdad teaching hospital and AL-Kadhumain teaching hospital during the period between the 1st. of December ...

Indian journal of dermatology, venereology and leprology

HLA-DRB1*04, -DRB1*08, -DRB1*14, -DQB1*03 and -DQB1*05 are reported to have significant associati... more HLA-DRB1*04, -DRB1*08, -DRB1*14, -DQB1*03 and -DQB1*05 are reported to have significant association with pemphigus vulgaris; however, this is partially dependent on ethnicity. This study was done to determine the HLA-DR and -DQ types prevalent in Indian patients with pemphigus vulgaris. A prospective case-control study was done for a period of 9 months in Christian Medical College Vellore, India. HLA typing was done by PCR-SSOP method in 50 cases and 50 healthy controls. Allele frequencies in cases and controls were compared and odds ratios with 95% confidence interval were calculated. The mean age of the patients (29 females, 21 males) and that of controls (36 males, 14 females) were 41.3 ± 13.65 and 35.42 ± 11.09 years, respectively. HLA-DRB1*14 was present in 47 patients and 18 controls (OR, 27.85; 95% CI, 7.57-102.42) and HLA-DQB1*05 was seen in 47 patients and 24 controls (OR, 16.97; 95% CI, 4.66-61.80). The haplotype DRB1*14, DQB1*05 was present in 44 patients and 14 controls ...