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Sanjay Gandhi Postgraduate Institute of Medician Sciences, Lucknow
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Papers by lucas zanini
Pesticide consumption has increased considerably in the last years. Although pesticides have help... more Pesticide consumption has increased considerably in the last years. Although pesticides have helped to increase the crops’ productivity, they have been associated with the incidence of cancers. The objective of this study was to describe the epidemiological profile of cancer patients living in an area with high use of pesticide. A retrospective cohort design was used to describe cancer cases. Patients were included whenever (i) diagnosed with any type of cancer between 2005 and 2016; (ii) living, at the time of diagnosis, in one of the 69 Brazilian cities studied; and (iii) aged 12 years old or over. A multilevel regression model was used to model the cancer morbidity coefficient. A total of 10,640 cancer patients were studied. Cancer morbidity coefficients increased with age and were significantly higher among people residing in rural areas than among those living in urban areas (p-value<0.0001). In both urban and rural areas, males showed significantly higher cancer morbidity c...
Revista do Colégio Brasileiro de Cirurgiões
RESUMO Objetivos: Analisar os resultados de morbidade e sobrevida após cirurgias curativas e pali... more RESUMO Objetivos: Analisar os resultados de morbidade e sobrevida após cirurgias curativas e paliativas em pacientes com câncer cervical recidivado após tratamento primário com radioterapia e quimioterapia. Outro objetivo foi avaliar os fatores associados aos procedimentos curativos e não curativos. Métodos: Coorte retrospectiva de pacientes submetidos à cirurgias curativas e paliativas, entre janeiro de 2011 a dezembro de 2017, em um centro de alta complexidade em oncolologia. O desfecho da morbidade foi relatado de acordo com a classificação de Clavien-Dindo e a análise de sobrevida foi realizada pelo método de Kaplan-Meir. Para avaliar os fatores associados aos procedimentos, foi realizada análise univariada pelo teste U de Mann-Whitney. Resultados: Foram realizadas duas histerectomias radicais, três exenterações pélvicas com intenção curativa e cinco exenterações pélvicas paliativas. No grupo curativo, houve complicações maiores em 40% dos casos, e o tempo mediano de sobrevida f...
Revista do Colégio Brasileiro de Cirurgiões
Objective: to compare abdominal computer tomography (CT) with isolated serial clinical exam (SCE)... more Objective: to compare abdominal computer tomography (CT) with isolated serial clinical exam (SCE) in the management of anterior abdominal stab wounds. Methods: randomized prospective study performed at Hospital de Pronto Socorro de Porto Alegre involving patients with anterior abdominal stab wounds without indication of immediate laparotomy; patients were divided in two groups: CT group and SCE group, In the SCE group, patients were followed up with serial clinical exam every 6 hours, Patients of CT group were submitted to abdominal computer tomography after initial evaluation. Results: 66 patients were studied and 33 were included in each group, Of total, six were submitted to surgery, three of each group, In the SCE group, patients submitted to surgery in media waited 12 hours from arrival to diagnosis without any non-therapeutic surgeries, The remaining 30 patients of this group were discharged from hospital after 24 hours of observation, In the CT group, three patients showed al...
Journal of Surgical Oncology
Saúde em Debate
We conducted an integrative literature review of published studies on pesticide and cancer exposu... more We conducted an integrative literature review of published studies on pesticide and cancer exposure, focusing on farmers, rural population, pesticide applicators, and rural workers. The Medline/PubMed was used as searching database. After the retrieval, 74 articles were selected according to pre-established criteria, which design involved 39 case-controls, 32 cohorts, 2 ecological ones, and 1 cross-sectional. Among them, 64 studies showed associations between pesticides and cancer while 10 did not find any significant association. The studies found 53 different types of pesticides significantly associated with at least one type of cancer and 19 different types of cancers linked to at least one type of pesticide. Although few studies presented contradictory results, the sole fact of being a farmer or living near crops or high agricultural areas have also been used as a proxy for pesticide exposure and significantly associated with higher cancer risk. The literature well illustrates t...
Journal of Surgical Oncology
Pesticide consumption has increased considerably in the last years. Although pesticides have help... more Pesticide consumption has increased considerably in the last years. Although pesticides have helped to increase the crops’ productivity, they have been associated with the incidence of cancers. The objective of this study was to describe the epidemiological profile of cancer patients living in an area with high use of pesticide. A retrospective cohort design was used to describe cancer cases. Patients were included whenever (i) diagnosed with any type of cancer between 2005 and 2016; (ii) living, at the time of diagnosis, in one of the 69 Brazilian cities studied; and (iii) aged 12 years old or over. A multilevel regression model was used to model the cancer morbidity coefficient. A total of 10,640 cancer patients were studied. Cancer morbidity coefficients increased with age and were significantly higher among people residing in rural areas than among those living in urban areas (p-value<0.0001). In both urban and rural areas, males showed significantly higher cancer morbidity c...
Revista do Colégio Brasileiro de Cirurgiões
RESUMO Objetivos: Analisar os resultados de morbidade e sobrevida após cirurgias curativas e pali... more RESUMO Objetivos: Analisar os resultados de morbidade e sobrevida após cirurgias curativas e paliativas em pacientes com câncer cervical recidivado após tratamento primário com radioterapia e quimioterapia. Outro objetivo foi avaliar os fatores associados aos procedimentos curativos e não curativos. Métodos: Coorte retrospectiva de pacientes submetidos à cirurgias curativas e paliativas, entre janeiro de 2011 a dezembro de 2017, em um centro de alta complexidade em oncolologia. O desfecho da morbidade foi relatado de acordo com a classificação de Clavien-Dindo e a análise de sobrevida foi realizada pelo método de Kaplan-Meir. Para avaliar os fatores associados aos procedimentos, foi realizada análise univariada pelo teste U de Mann-Whitney. Resultados: Foram realizadas duas histerectomias radicais, três exenterações pélvicas com intenção curativa e cinco exenterações pélvicas paliativas. No grupo curativo, houve complicações maiores em 40% dos casos, e o tempo mediano de sobrevida f...
Revista do Colégio Brasileiro de Cirurgiões
Objective: to compare abdominal computer tomography (CT) with isolated serial clinical exam (SCE)... more Objective: to compare abdominal computer tomography (CT) with isolated serial clinical exam (SCE) in the management of anterior abdominal stab wounds. Methods: randomized prospective study performed at Hospital de Pronto Socorro de Porto Alegre involving patients with anterior abdominal stab wounds without indication of immediate laparotomy; patients were divided in two groups: CT group and SCE group, In the SCE group, patients were followed up with serial clinical exam every 6 hours, Patients of CT group were submitted to abdominal computer tomography after initial evaluation. Results: 66 patients were studied and 33 were included in each group, Of total, six were submitted to surgery, three of each group, In the SCE group, patients submitted to surgery in media waited 12 hours from arrival to diagnosis without any non-therapeutic surgeries, The remaining 30 patients of this group were discharged from hospital after 24 hours of observation, In the CT group, three patients showed al...
Journal of Surgical Oncology
Saúde em Debate
We conducted an integrative literature review of published studies on pesticide and cancer exposu... more We conducted an integrative literature review of published studies on pesticide and cancer exposure, focusing on farmers, rural population, pesticide applicators, and rural workers. The Medline/PubMed was used as searching database. After the retrieval, 74 articles were selected according to pre-established criteria, which design involved 39 case-controls, 32 cohorts, 2 ecological ones, and 1 cross-sectional. Among them, 64 studies showed associations between pesticides and cancer while 10 did not find any significant association. The studies found 53 different types of pesticides significantly associated with at least one type of cancer and 19 different types of cancers linked to at least one type of pesticide. Although few studies presented contradictory results, the sole fact of being a farmer or living near crops or high agricultural areas have also been used as a proxy for pesticide exposure and significantly associated with higher cancer risk. The literature well illustrates t...
Journal of Surgical Oncology