Ian Burgess - Academia.edu (original) (raw)

Papers by Ian Burgess

Research paper thumbnail of Treatment of head lice with dimeticone 4% lotion: comparison of two …

BMC Public …

Dimeticone 4% lotion was shown to be an effective treatment for head louse infestation in two ran... more Dimeticone 4% lotion was shown to be an effective treatment for head louse infestation in two randomised controlled trials in England. It is not affected by insecticide resistance but efficacy obtained (70-75%) was lower than expected. This study was designed to evaluate ...

Research paper thumbnail of Sarcoptes scabiei and scabies

Advances in Parasitology, Feb 1, 1994

... However, you may be able to access this article under your organization's agreement with... more ... However, you may be able to access this article under your organization's agreement with Elsevier.Ian Burgess a. a Medical Entomology Centre, University of Cambridge, Cambridge Road, Fulbourn, Cambridge, CB1 5EL, UK. Available online 5 May 2008. Excerpt. ...

Research paper thumbnail of Re: Head Lice: standards in clinical trial design - authors' reply

Research paper thumbnail of Adverse reactions to monosulfiram

Research paper thumbnail of Carbaryl lotions for head lice - new laboratory tests show variations in efficacy

Pharmaceutical Journal, 1990

Research paper thumbnail of Self Care of Head Louse Infestation

Selfcare Journal, Apr 19, 2010

Research paper thumbnail of Treating head lice. Commentaries

Bmj British Medical Journal, 2003

Research paper thumbnail of The Function of a Repellent in Head Louse Control

Pharmaceutical Journal, 1993

Research paper thumbnail of Dermatopharmacology of Antiparasitics and Insect Repellents

Dermatopharmacology of Topical Preparations, 2000

Research paper thumbnail of Head lice

BMJ clinical evidence, 2009

Head lice can only be diagnosed by finding live lice, as eggs take 7 days to hatch and may appear... more Head lice can only be diagnosed by finding live lice, as eggs take 7 days to hatch and may appear viable for weeks after death of the egg. Infestation may be more likely in school children, with risks increased in children with more siblings, longer hair, and of lower socioeconomic group. We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for head lice? We searched: Medline, Embase, The Cochrane Library, and other important databases up to June 2008 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). We found 15 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions...

Research paper thumbnail of Head lice

Clinical evidence, 2002

ABSTRACT

Research paper thumbnail of Maintenance of the crab louse, Pthirus pubis, in the laboratory and behavioural studies using volunteers

Community medicine, 1983

Infections with crab lice (Pthirus pubis) remain common and may be increasing. These are difficul... more Infections with crab lice (Pthirus pubis) remain common and may be increasing. These are difficult insects to maintain in captivity and in consequence their behaviour has been poorly studied. We were able to breed them in semi-natural conditions and obtained enough to be able to study their behaviour during the twenty-four hours following being released onto a volunteer. The results indicated that they are a more mobile insect than was previously thought and this finding has influenced our beliefs concerning their transference between hosts

Research paper thumbnail of Kindaped™ lotion for treatment of head lice

http://isrctn.org/>, 2000

Research paper thumbnail of A randomised, controlled, assessor-blind, clinical trial to demonstrate superiority of Hedrin 4% dimeticone lotion compared with Derbac-M 0.5% malathion aqueous liquid in the treatment of head lice

http://isrctn.org/>, 2000

Research paper thumbnail of 0.4% Dimeticone spray, a novel physically acting household treatment for control of cat fleas

Veterinary Parasitology, 2014

The cat flea, Ctenocephalides felis, is the most important ectoparasite of cats and dogs worldwid... more The cat flea, Ctenocephalides felis, is the most important ectoparasite of cats and dogs worldwide as a cause of irritation and health problems. Most products to control these pests in the household environment rely upon a combination of neurotoxic insecticides and insect growth regulators to inhibit development of flea eggs and larvae into adults. However, some of these are affected by problems of insecticide resistance as well as public concerns about their potential for toxicity in domestic use. Heavy synthetic oils, like the siloxane dimeticone, are currently widely used to treat human ectoparasite infestations, acting by a physical mode of action, and have been used in a variety of presentations for killing all life stages of fleas. We have investigated the activity of low concentrations of high molecular weight dimeticone in a volatile silicone base for ability to immobilise flea life stages without asphyxiating them. We found that cat flea adults and larvae were immobilised by a surface film of dimeticone that inhibited movement of cuticular joints, apparently forming an effective sticky trap. When cocoons were treated the fleas continued to develop within the pupae but failed to emerge. An aerosol spray incorporating 0.4% concentration of dimeticone, for use as a residual household treatment, showed no significant difference in knock down capability compared with that of a widely used pyriproxifen/permethrin spray in a repeat challenge test, with effects persisting to inhibit adult flea emergence in the test arena area for more than 3 weeks after application.

Research paper thumbnail of Sciapods and elephantiasis

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1991

Research paper thumbnail of A pilot study on the effect of one room mechanical ventilation with heat recovery (MVHR) units on house dust mite populations and Der p 1 levels in laboratory simulated bedrooms and on ambient conditions in an occupied bedroom in Cambridge, UK

International Journal of Environmental Health Research, 1996

Page 1. International Journal of Environmental Health Research 6, 301-313 (1996) A pilot study on... more Page 1. International Journal of Environmental Health Research 6, 301-313 (1996) A pilot study on the effect of one room mechanical ventilation with heat recovery (MVHR) units on house dust mite populations and Der p 1 levels in laboratory simulated ...

Research paper thumbnail of Review : Allergic Reactions to Arthropods

Indoor and Built Environment, 1993

Abstract Allergic reactions to arthropods are some of the most important factors involved in the ... more Abstract Allergic reactions to arthropods are some of the most important factors involved in the development of asthma and the precipitation of attacks. Although sensitization to arthropods occurs most frequently in atopic individ uals, continual exposure induces ...

Research paper thumbnail of Randomised, controlled, parallel group clinical trials to evaluate the efficacy of isopropyl myristate/cyclomethicone solution against head lice

Pharmaceutical journal, 2008

RefDoc Bienvenue - Welcome. Refdoc est un service / is powered by. ...

Research paper thumbnail of Myiasis due to Parasarcophaga argyrostoma-first recorded case in Britain

Clinical and Experimental Dermatology, 1992

ABSTRACT

Research paper thumbnail of Treatment of head lice with dimeticone 4% lotion: comparison of two …

BMC Public …

Dimeticone 4% lotion was shown to be an effective treatment for head louse infestation in two ran... more Dimeticone 4% lotion was shown to be an effective treatment for head louse infestation in two randomised controlled trials in England. It is not affected by insecticide resistance but efficacy obtained (70-75%) was lower than expected. This study was designed to evaluate ...

Research paper thumbnail of Sarcoptes scabiei and scabies

Advances in Parasitology, Feb 1, 1994

... However, you may be able to access this article under your organization's agreement with... more ... However, you may be able to access this article under your organization's agreement with Elsevier.Ian Burgess a. a Medical Entomology Centre, University of Cambridge, Cambridge Road, Fulbourn, Cambridge, CB1 5EL, UK. Available online 5 May 2008. Excerpt. ...

Research paper thumbnail of Re: Head Lice: standards in clinical trial design - authors' reply

Research paper thumbnail of Adverse reactions to monosulfiram

Research paper thumbnail of Carbaryl lotions for head lice - new laboratory tests show variations in efficacy

Pharmaceutical Journal, 1990

Research paper thumbnail of Self Care of Head Louse Infestation

Selfcare Journal, Apr 19, 2010

Research paper thumbnail of Treating head lice. Commentaries

Bmj British Medical Journal, 2003

Research paper thumbnail of The Function of a Repellent in Head Louse Control

Pharmaceutical Journal, 1993

Research paper thumbnail of Dermatopharmacology of Antiparasitics and Insect Repellents

Dermatopharmacology of Topical Preparations, 2000

Research paper thumbnail of Head lice

BMJ clinical evidence, 2009

Head lice can only be diagnosed by finding live lice, as eggs take 7 days to hatch and may appear... more Head lice can only be diagnosed by finding live lice, as eggs take 7 days to hatch and may appear viable for weeks after death of the egg. Infestation may be more likely in school children, with risks increased in children with more siblings, longer hair, and of lower socioeconomic group. We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for head lice? We searched: Medline, Embase, The Cochrane Library, and other important databases up to June 2008 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). We found 15 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions...

Research paper thumbnail of Head lice

Clinical evidence, 2002

ABSTRACT

Research paper thumbnail of Maintenance of the crab louse, Pthirus pubis, in the laboratory and behavioural studies using volunteers

Community medicine, 1983

Infections with crab lice (Pthirus pubis) remain common and may be increasing. These are difficul... more Infections with crab lice (Pthirus pubis) remain common and may be increasing. These are difficult insects to maintain in captivity and in consequence their behaviour has been poorly studied. We were able to breed them in semi-natural conditions and obtained enough to be able to study their behaviour during the twenty-four hours following being released onto a volunteer. The results indicated that they are a more mobile insect than was previously thought and this finding has influenced our beliefs concerning their transference between hosts

Research paper thumbnail of Kindaped™ lotion for treatment of head lice

http://isrctn.org/>, 2000

Research paper thumbnail of A randomised, controlled, assessor-blind, clinical trial to demonstrate superiority of Hedrin 4% dimeticone lotion compared with Derbac-M 0.5% malathion aqueous liquid in the treatment of head lice

http://isrctn.org/>, 2000

Research paper thumbnail of 0.4% Dimeticone spray, a novel physically acting household treatment for control of cat fleas

Veterinary Parasitology, 2014

The cat flea, Ctenocephalides felis, is the most important ectoparasite of cats and dogs worldwid... more The cat flea, Ctenocephalides felis, is the most important ectoparasite of cats and dogs worldwide as a cause of irritation and health problems. Most products to control these pests in the household environment rely upon a combination of neurotoxic insecticides and insect growth regulators to inhibit development of flea eggs and larvae into adults. However, some of these are affected by problems of insecticide resistance as well as public concerns about their potential for toxicity in domestic use. Heavy synthetic oils, like the siloxane dimeticone, are currently widely used to treat human ectoparasite infestations, acting by a physical mode of action, and have been used in a variety of presentations for killing all life stages of fleas. We have investigated the activity of low concentrations of high molecular weight dimeticone in a volatile silicone base for ability to immobilise flea life stages without asphyxiating them. We found that cat flea adults and larvae were immobilised by a surface film of dimeticone that inhibited movement of cuticular joints, apparently forming an effective sticky trap. When cocoons were treated the fleas continued to develop within the pupae but failed to emerge. An aerosol spray incorporating 0.4% concentration of dimeticone, for use as a residual household treatment, showed no significant difference in knock down capability compared with that of a widely used pyriproxifen/permethrin spray in a repeat challenge test, with effects persisting to inhibit adult flea emergence in the test arena area for more than 3 weeks after application.

Research paper thumbnail of Sciapods and elephantiasis

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1991

Research paper thumbnail of A pilot study on the effect of one room mechanical ventilation with heat recovery (MVHR) units on house dust mite populations and Der p 1 levels in laboratory simulated bedrooms and on ambient conditions in an occupied bedroom in Cambridge, UK

International Journal of Environmental Health Research, 1996

Page 1. International Journal of Environmental Health Research 6, 301-313 (1996) A pilot study on... more Page 1. International Journal of Environmental Health Research 6, 301-313 (1996) A pilot study on the effect of one room mechanical ventilation with heat recovery (MVHR) units on house dust mite populations and Der p 1 levels in laboratory simulated ...

Research paper thumbnail of Review : Allergic Reactions to Arthropods

Indoor and Built Environment, 1993

Abstract Allergic reactions to arthropods are some of the most important factors involved in the ... more Abstract Allergic reactions to arthropods are some of the most important factors involved in the development of asthma and the precipitation of attacks. Although sensitization to arthropods occurs most frequently in atopic individ uals, continual exposure induces ...

Research paper thumbnail of Randomised, controlled, parallel group clinical trials to evaluate the efficacy of isopropyl myristate/cyclomethicone solution against head lice

Pharmaceutical journal, 2008

RefDoc Bienvenue - Welcome. Refdoc est un service / is powered by. ...

Research paper thumbnail of Myiasis due to Parasarcophaga argyrostoma-first recorded case in Britain

Clinical and Experimental Dermatology, 1992

ABSTRACT