neda taner | Istanbul Medipol University (original) (raw)

Papers by neda taner

Istanbul Medical Journal, Oct 8, 2018

There are plenty of factors that change the clinical impacts of drugs. Some of them are genetic, ... more There are plenty of factors that change the clinical impacts of drugs. Some of them are genetic, physiological and drug-drug interactions. However, drug-drug interaction is the preliminary factor because of the drugs’ relationship with CYP family, especially with CYP3A4. The objective of this study is to discuss the effect of CYP3A4 dependent drug interactions about cardiovascular drugs. In this paper, a literature search was performed using PubMed, MEDLINE, Web of Science, and the Cochrane Library to analyze the pharmacokinetic drug-drug interactions associated with CYP3A4 isoenzyme. As a result, we showed the importance of drug-drug interaction related to CYP3A4 isoenzyme that has an affect on drugs used in cardiovascular diseases. In conclusion, although we found lots of drug-drug interactions related to CYP3A4 isoenzyme on cardiovascular drugs, future studies should be done for exact information about this topic.

Journal of Pharmaceutical Care, 2021

Background: Type 2 diabetes is a serious condition that is rapidly increasing all over the world ... more Background: Type 2 diabetes is a serious condition that is rapidly increasing all over the world and can cause other metabolic diseases. In our study, we aimed to evaluate the probability of the participants having Type 2 diabetes by using diabetes risk questionnaire. Methods: During the month of March 2019, a validated questionnaire prepared by the Turkish Diabetes Association was administered to 500 patients (M= 223, (44.6%); (F= 277), (55.4%)) who were applying to a pharmacy in Zeytinburnu, Istanbul. Statistical analyzes were performed using SPSS version 21. Data were expressed as mean, standard deviation (SD) and percentage (%). In this respect, the normality of data distribution was determined by the Shapiro-Wilk test. Results: The scale total scores of women were significantly lower than the total scale scores of men (p<0.001). It was found that the risk of developing diabetes increased significantly with age (p <0.001). Patients aged 60 and over were at the highest risk...

ACTA Pharmaceutica Sciencia, 2020

Type 2 Diabetes is a common incurable metabolic disorder with worldwide increasing prevalence. In... more Type 2 Diabetes is a common incurable metabolic disorder with worldwide increasing prevalence. International Diabetic Association noticed that there is a very fast and alarming increase in the worldwide prevalence of Diabetes. In 2012, diabetic population around the world has reached 371 million people. Untreated or undertreated Type 2 Diabetes does affect the quality of life of the patients both directly by symptoms and indirectly by short term and long-term complications. In addition to the direct effects of type 2 diabetes mellitus, affects the patient's life in a bad way, if the treatment process is not followed carefully, the quality of life of the patient will be reduced. At this point, clinical pharmacist has an extremely important role in determining and executing the correct clinical treatment. Besides that, the importance of the patient's level of knowledge about the disease and its impact on the treatment process is very important. The major goal of this thesis is evaluating the diabetic patients` knowledge on diabetes and the effect of this point on treatment process. This study has been done in Merve Pharmacy of Muğla/Turkey between January and March of 2018. A questionnaire consisting of 20 multiple choice questions has been used to evaluate 50 participants who are clinically diagnosed diabetics. SPSS 23.0 statistical program was used for the statistical analysis of the data and the findings were evaluated at and 5% significance level. It has been statistically observed that knowledge levels of patients affected the treatment process. Recognizing the importance of this factor by clinical pharmacists and other health professionals will increase the training for diabetes and prevent the problems arising from the patient's low-level knowledge.

1 İstanbul Medipol University, School of Pharmacy, Department of Pharmacology, Istanbul, Turkey. ... more 1 İstanbul Medipol University, School of Pharmacy, Department of Pharmacology, Istanbul, Turkey. 2 İstanbul Medipol University, School of Pharmacy, Department of Pharmaceutical Toxicology, Istanbul, Turkey. 3 İstanbul Medipol University, School of Pharmacy, Department of Pharmaceutical Technology, Istanbul, Turkey. 4 İstanbul Medipol University, School of Pharmacy, Department of Clinical Pharmacy, Istanbul, Turkey. 5 İstanbul Medipol University, School of Pharmacy, Istanbul, Turkey.

ACTA Pharmaceutica Sciencia

Obturator neuropathy (ON) is an illness presenting with sensory loss, pain or weakness with leg a... more Obturator neuropathy (ON) is an illness presenting with sensory loss, pain or weakness with leg adduction. Guillain-Barre Syndrome (GBS) has similar symptoms. The most determinative diagnostic parameters are nerve conduction in both diseases. 1,2 Therefore, GBS may also leads to ON whether it was diagnosed late. There have been lots of studies in literatures about these illnesses,

Journal of Developing Drugs, 2016

Like in other industries, the competition among companies in the pharma industry is high. Therefo... more Like in other industries, the competition among companies in the pharma industry is high. Therefore, pharmaceutical companies have to design their strategies in order to achieve competitive advantage. Brand loyalty is a powerful tool in the development of pharmaceutical brands. Physicians play major role in the selection of drugs to consume and can also be considered as the consumer. This descriptive study examines the factors that influence physicians' choices of medication for their patients. Data was collected using a survey administered to specialists and trainees from Cardiology Department. Total 18 physicians participated in the study. Most of the respondents (85%) declared the scientific literature regarding the drug as their first priority in prescribing. Almost half of the respondents (46%) declared the published clinical trial results as a primary source of information about the launch of new drug. With respect to the inclusion of a newly launched drug in the daily prescribing routine, 85% of the respondents tended to prescribe a new drug after the publication of clinical trials. A vast majority of the participants indicated the patients' source of payment as a major factor for their preferences; meanwhile 92% of them also emphasized the therapeutic equivalency of the drug for their preferences. More than half of the participants (>70%) tended to prescribe original drugs to patients having chronic disease/comorbidity and special insurance coverage and/or self-payment. Regarding the physicians' familiarity to the original proprietary names, more than half of the respondents correctly predicted the original proprietary names. This study reflects the physician's perspective for the establishment of brand loyalty. From the physicians' standpoint belief in brand is crucial for the creation of brand loyalty and the key for building up trust is the scientific data regarding the effectiveness and safety of the drug obtained from large-scale clinical trials.

ACTA Pharmaceutica Sciencia, Dec 22, 2020

Probiotics are selectable viable microorganisms used as nutritional supplements that contribute t... more Probiotics are selectable viable microorganisms used as nutritional supplements that contribute to maintaining human health or have potential benefits for disease prevention. 1 On the other hand, prebiotics, are defined as food components that stimulate the reproduction and activity of beneficial bacteria in the colon, thereby indirectly cause benefit to the host. 2 Symbiotics are also non-digestible substances that activate or strengthen the effect of probiotic bacteria with the po-ABSTRACT This research; is planned to determine the level of knowledge about probiotic nutritions and, the consumption of them by university students. The date range of the study was 2018. A total of 100 students were surveyed at the İstanbul Medipol University, 47 men and 53 women aged 18-30 years. General information and demographic status of participants were questioned. Also, height and weight data were recorded by their written notifications. In parallel with the ever-increasing work on the positive effects of probiotics on health; increased consumption of probiotics and increased knowledge. Microorganisms can directly or indirectly cause the formation of many diseases. 20% of the students consume these nutrients on the recommendation; and 24% of them did not consume it because they think did not need it. Although probiotic dairy products are mostly used for symptoms of constipation, there is not enough information in the context of other diseases.