Siddharth Matad | Jain University (original) (raw)

Papers by Siddharth Matad

Indian journal of vascular and endovascular surgery, 2024

Indian journal of vascular and endovascular surgery IJVES. CInI- case reports, innovations and images, 2024

International Surgery Journal, Jan 25, 2017

Background: Acute pancreatitis still remains a disease of growing burden to mankind; it is an unp... more Background: Acute pancreatitis still remains a disease of growing burden to mankind; it is an unpredictable, potentially lethal disease with a high mortality. The incidence of acute Pancreatitis appears to be increasing. Aim of the study was to evaluate total serum calcium and corrected calcium as prognostic severity factors in acute pancreatitis. Methods: This prospective study was conducted in a tertiary hospital from July2015 to June 2016. All the patients who were diagnosed to have acute pancreatitis by clinical examination, laboratory, radiological and biochemical investigations were considered as cases. Serum calcium and albumin corrected calcium measured within 24 hours of admission. Patients followed up for a maximum period of 4 weeks and outcome studied, in terms of whether patient had local or systemic complication, mortality. Significance of serum calcium and albumin corrected calcium in predicting outcome of acute pancreatitis is assessed and compared with BISAP score. Results: Acute pancreatitis most commonly occurs in the age group of 30-50. 80% of acute pancreatitis occurs in male and 20% in female. Alcoholism accounts for 58% cases of acute pancreatitis and gall stone account for 28% of acute pancreatitis. Conclusions: Hypocalcaemia and low ACC can predict severity of acute pancreatitis, as with BISAP score, but it is not superior to BISAP score.

Annals of International medical and Dental Research, 2017

Enterolithiasis, or presence of stone concretions in the gastrointestinal tract, is an important ... more Enterolithiasis, or presence of stone concretions in the gastrointestinal tract, is an important but relatively uncommon clinical condition. It is most commonly found in animals especially equines. In humans clinical presentation of this condition is varied and sometimes masquerading other intra abdominal pathologies. Clinically insignificant incidentally noted enteroliths may shift attention from primary non-enterolith related pathology of the patient that may be responsible for a current clinical presentation. Here we are reporting four cases of incidentally detected enterolithiasis at our hospital with review of literature.

Indian journal of applied research, 2017

Cholelithiasis is one of the costliest diseases to treat following GERD. Gallstones are considere... more Cholelithiasis is one of the costliest diseases to treat following GERD. Gallstones are considered to be tomb of dead bacteria .numerous studies have been done to show the infective nature of the bile but we did this study to analyze the microbiological profile of gall stone.We conducted a cross sectional study of 100 cholelithiasis patients undergoing operative procedure at our department. microbiological analysis of gallstone was done for all patients under study after obtaining proper ethics committee permission. Results showed that gallstones are no more tombs of dead bacteria, with e coli as most common bacteria isolated.

Annals of International Medical and Dental Research, 2017

Background: Varicose veins are commonly encountered vascular disease with wide variety of surgica... more Background: Varicose veins are commonly encountered vascular disease with wide variety of surgical and minimally invasive /interventional modes of treatment .we put forth a novel economical and efficient technique of performing high ligation, long saphenous vein stripping and Muller's hook phlebectomy in tumescent local anaesthesia compared with spinal anaesthesia. AIM &OBJECTIVE: The purpose of the study was to compare a novel technique of performing phlebectomy and invagination stripping of the GSV using tumescent anesthesia and spinal anesthesia in terms of post operative pain, complications. Methods: A total of 200 patients (100 patients in each arm of spinal anaesthesia group, and tumescent anaesthesia group) diagnosed cases of varicose vein lower limb being operated with phlebectomy and invagination stripping of the GSV at

Annals of International medical and Dental Research, 2018

Background: Trauma is the most common cause of death in people younger than 45 years of age and a... more Background: Trauma is the most common cause of death in people younger than 45 years of age and accounts for more years of life loss than cancer, heart disease, and stroke combined. Aim: 1. To establish the pattern and outcome of solid visceral injuries in blunt abdominal trauma, 2. Most reliable investigation for diagnosing a case of solid visceral injury in blunt trauma abdomen, 3. To analyse the various modalities of treatment and interventions done for solid visceral injury in a blunt abdominal trauma patient. Methods: Prospective Observational study conducted over one year between august 2016 to august 2017 at Department of surgery, Government Medical College, Kozhikode. Results: Among 180 patients, 82 cases [45.6%] were in age group 21-40 yrs. There were 151 males out of 180 cases [83.9 %].. Male to female ratio was 5.2:1. Most common mode of injury was road traffic accident [RTA] 47.8%. Conclusion: Blunt trauma was the commonest type of abdominal injury seen in our Department of Surgery and the spleen was found to be the most common organ injured in blunt trauma. The most common cause was road traffic accidents.

Annals of International medical and Dental Research, 2018

Background: Both hemorrhoids and fissure-in-ano contribute to the spectrum of anorectal disorders... more Background: Both hemorrhoids and fissure-in-ano contribute to the spectrum of anorectal disorders which generate significant patient discomfort and disability. Etiological factors associated with development of symptomatic hemorrhoids include intake of low fiber diet, inadequate fluid intake, altered bowel habits leading to constipation etc. Aim: 1.To study the dietary habits of patients presenting with haemorrhoids and fissure in ano. 2. To determine the effect of altered dietary habits on the symptomatology. Methods: Case Control study conducted over one year between august 2016 to august 2017 at Department of surgery, Government Medical College, MANJERI. Results: The mean age of patients having hemorrhoids is 42.9years in case group and 44.0years in control group. Where as, the mean age of patients with fissure-inano is 37.1years in case group and 39.6years in control group. Majority of patients in the study population of hemorrhoids are male (84%) while female patients (56%) have more anal fissures. The p value of all analysis is <0.05. Conclusion: From this study, it has been concluded that in patients with hemorrhoids, bleeding per rectum gets aggravated with consumption of non vegetarian food items, fasting in the morning and intake of ≤ 1L of oral liquids and reduced consumption of diet containing fibre.

International Surgery Journal, 2017

Background: Gallstone disease is one of the most common digestive system diseases next to GERD an... more Background: Gallstone disease is one of the most common digestive system diseases next to GERD and accepted treatment involves laparoscopic or open cholecystectomy making it one of the costly diseases. with increasing westernisation of Indian lifestyle and food and also recent studies pointing out its association with cardiovascular disease and cancer mortality its need of the time to undertake an extensive study on epidemiology, demography and risk factors of gallstone disease. The aim was to study the epidemiological, demographic and risk factor profile in patients harbouring various types of gallbladder calculi.Methods: A cross sectional prospective study was conducted. 100 cholelithiasis patients were undergoing operative procedure at our department.Results: Showed that females had higher incidence of gallstone disease with a ratio of 2:1, mixed gallstone was the predominant type (53%), mean BMI of the study population was 28.03 with SD of 3.61.Conclusions: Women are twice as li...

International Surgery Journal, 2017

Background: Diabetes mellitus is a chronic disorder affecting large segment of population and is ... more Background: Diabetes mellitus is a chronic disorder affecting large segment of population and is a major public health problem.Methods: A prospective cross sectional study of 150 patients conducted in the Department of Surgery at Government Medical College, Kozhikode, Kerala, IndiaResults: Maximum numbers of patients were in the age group of 60-69. Male to female ratio is 3.04:1.50% had duration of diabetes <10 years and 50% had duration ≥10. years. 81 (54%) patients had neuropathy, 53 (35.3%) had PVD, 41 (27.3%) had history of prior foot ulcer, 70 (46.7%) had poor glycemic control (RBS >200 mg/dl) at the time of admission and 44 (29.3%) had history of smoking.Conclusions: Most important risk factors for diabetic foot ulcers were neuropathy (54%), poor glycemic control (46.7%) and PVD (35.3%), diabetic foot requires a comprehensive management.

http://isrctn.org/>, 2012

Background: Adjunctive uterotonic in patients at risk of primary post-partum haemorrhage may redu... more Background: Adjunctive uterotonic in patients at risk of primary post-partum haemorrhage may reduce its incidence. Objective: To compare the effectiveness and safety of adjunctive rectal misoprostol with adjunctive intravenous oxytocin for the prevention of primary post-partum haemorrhage in at risk patients. Materials and methods: A total of 122 patients with risk factors for uterine atony were allocated to receive either 600μg of rectal misoprostol (n= 61) or 20IU of oxytocin infusion (n=61) after routine management of third stage of labour. Post-partum blood loss was measured using differential delivery towel and pad weighing. Results: There was similarity in the estimated post-partum blood loss, with no significant difference in the mean post-partum hematocrit levels between the adjunctive rectal misoprostol group and oxytocin infusion group (P=0.712). There was no difference in the need for additional intervention of uterotonics between the two groups. There were however, higher incidences of shivering and pyrexia among those that received misoprostol compared with the oxytocin group. Conclusion: Rectal misoprostol is as effective and safe as oxytocin when used as an adjunctive uterotonic in preventing primary post-partum haemorrhage in patients with risk factors for uterine atony after active management of third stage of labour.

Revista de Gastroenterología de México, 2014

Objectives: To evaluate total serum calcium (TC) and albumin-corrected calcium (ACC) as prognosti... more Objectives: To evaluate total serum calcium (TC) and albumin-corrected calcium (ACC) as prognostic severity factors in acute pancreatitis (AP). Methods: Ninety-six patients were included in the study. They were diagnosed with AP and admitted to the Hospital Regional de Veracruz within the time frame of January 2010 to December 2012. AP severity was determined through the updated Atlanta Classification (2013). TC and ACC values were measured in the first 24 hours of admittance and the percentages of sensitivity (S), specificity (Sp), positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (LR +), and negative likelihood ratio (LR-) were calculated through ROC curves and contingency tables. Results: In accordance with the updated Atlanta Classification, 70 patients presented with mild AP, 17 with moderately severe AP, and 9 with severe AP. Of the patient total, 61.5% were women, and 69.8% presented with biliary etiology. The maximum TC cutoff point was 7.5 mg/dL, with values of S, 67%; Sp, 82%; PPV, 27%, and NPV, 96%. The maximum ACC cutoff point was 7.5 mg/dL, with values of S, 67%; Sp, 90%; PPV, 40%; NPV, 96%. Both had values similar to those of the Ranson and APACHE II prognostic scales. Conclusions: TC and ACC, measured within the first 24 hours, are useful severity predictors in acute pancreatitis, with sensitivity and predictive values comparable or superior to those of the conventional prognostic scales.

Indian journal of vascular and endovascular surgery, 2024

Indian journal of vascular and endovascular surgery IJVES. CInI- case reports, innovations and images, 2024

International Surgery Journal, Jan 25, 2017

Background: Acute pancreatitis still remains a disease of growing burden to mankind; it is an unp... more Background: Acute pancreatitis still remains a disease of growing burden to mankind; it is an unpredictable, potentially lethal disease with a high mortality. The incidence of acute Pancreatitis appears to be increasing. Aim of the study was to evaluate total serum calcium and corrected calcium as prognostic severity factors in acute pancreatitis. Methods: This prospective study was conducted in a tertiary hospital from July2015 to June 2016. All the patients who were diagnosed to have acute pancreatitis by clinical examination, laboratory, radiological and biochemical investigations were considered as cases. Serum calcium and albumin corrected calcium measured within 24 hours of admission. Patients followed up for a maximum period of 4 weeks and outcome studied, in terms of whether patient had local or systemic complication, mortality. Significance of serum calcium and albumin corrected calcium in predicting outcome of acute pancreatitis is assessed and compared with BISAP score. Results: Acute pancreatitis most commonly occurs in the age group of 30-50. 80% of acute pancreatitis occurs in male and 20% in female. Alcoholism accounts for 58% cases of acute pancreatitis and gall stone account for 28% of acute pancreatitis. Conclusions: Hypocalcaemia and low ACC can predict severity of acute pancreatitis, as with BISAP score, but it is not superior to BISAP score.

Annals of International medical and Dental Research, 2017

Enterolithiasis, or presence of stone concretions in the gastrointestinal tract, is an important ... more Enterolithiasis, or presence of stone concretions in the gastrointestinal tract, is an important but relatively uncommon clinical condition. It is most commonly found in animals especially equines. In humans clinical presentation of this condition is varied and sometimes masquerading other intra abdominal pathologies. Clinically insignificant incidentally noted enteroliths may shift attention from primary non-enterolith related pathology of the patient that may be responsible for a current clinical presentation. Here we are reporting four cases of incidentally detected enterolithiasis at our hospital with review of literature.

Indian journal of applied research, 2017

Cholelithiasis is one of the costliest diseases to treat following GERD. Gallstones are considere... more Cholelithiasis is one of the costliest diseases to treat following GERD. Gallstones are considered to be tomb of dead bacteria .numerous studies have been done to show the infective nature of the bile but we did this study to analyze the microbiological profile of gall stone.We conducted a cross sectional study of 100 cholelithiasis patients undergoing operative procedure at our department. microbiological analysis of gallstone was done for all patients under study after obtaining proper ethics committee permission. Results showed that gallstones are no more tombs of dead bacteria, with e coli as most common bacteria isolated.

Annals of International Medical and Dental Research, 2017

Background: Varicose veins are commonly encountered vascular disease with wide variety of surgica... more Background: Varicose veins are commonly encountered vascular disease with wide variety of surgical and minimally invasive /interventional modes of treatment .we put forth a novel economical and efficient technique of performing high ligation, long saphenous vein stripping and Muller's hook phlebectomy in tumescent local anaesthesia compared with spinal anaesthesia. AIM &OBJECTIVE: The purpose of the study was to compare a novel technique of performing phlebectomy and invagination stripping of the GSV using tumescent anesthesia and spinal anesthesia in terms of post operative pain, complications. Methods: A total of 200 patients (100 patients in each arm of spinal anaesthesia group, and tumescent anaesthesia group) diagnosed cases of varicose vein lower limb being operated with phlebectomy and invagination stripping of the GSV at

Annals of International medical and Dental Research, 2018

Background: Trauma is the most common cause of death in people younger than 45 years of age and a... more Background: Trauma is the most common cause of death in people younger than 45 years of age and accounts for more years of life loss than cancer, heart disease, and stroke combined. Aim: 1. To establish the pattern and outcome of solid visceral injuries in blunt abdominal trauma, 2. Most reliable investigation for diagnosing a case of solid visceral injury in blunt trauma abdomen, 3. To analyse the various modalities of treatment and interventions done for solid visceral injury in a blunt abdominal trauma patient. Methods: Prospective Observational study conducted over one year between august 2016 to august 2017 at Department of surgery, Government Medical College, Kozhikode. Results: Among 180 patients, 82 cases [45.6%] were in age group 21-40 yrs. There were 151 males out of 180 cases [83.9 %].. Male to female ratio was 5.2:1. Most common mode of injury was road traffic accident [RTA] 47.8%. Conclusion: Blunt trauma was the commonest type of abdominal injury seen in our Department of Surgery and the spleen was found to be the most common organ injured in blunt trauma. The most common cause was road traffic accidents.

Annals of International medical and Dental Research, 2018

Background: Both hemorrhoids and fissure-in-ano contribute to the spectrum of anorectal disorders... more Background: Both hemorrhoids and fissure-in-ano contribute to the spectrum of anorectal disorders which generate significant patient discomfort and disability. Etiological factors associated with development of symptomatic hemorrhoids include intake of low fiber diet, inadequate fluid intake, altered bowel habits leading to constipation etc. Aim: 1.To study the dietary habits of patients presenting with haemorrhoids and fissure in ano. 2. To determine the effect of altered dietary habits on the symptomatology. Methods: Case Control study conducted over one year between august 2016 to august 2017 at Department of surgery, Government Medical College, MANJERI. Results: The mean age of patients having hemorrhoids is 42.9years in case group and 44.0years in control group. Where as, the mean age of patients with fissure-inano is 37.1years in case group and 39.6years in control group. Majority of patients in the study population of hemorrhoids are male (84%) while female patients (56%) have more anal fissures. The p value of all analysis is <0.05. Conclusion: From this study, it has been concluded that in patients with hemorrhoids, bleeding per rectum gets aggravated with consumption of non vegetarian food items, fasting in the morning and intake of ≤ 1L of oral liquids and reduced consumption of diet containing fibre.

International Surgery Journal, 2017

Background: Gallstone disease is one of the most common digestive system diseases next to GERD an... more Background: Gallstone disease is one of the most common digestive system diseases next to GERD and accepted treatment involves laparoscopic or open cholecystectomy making it one of the costly diseases. with increasing westernisation of Indian lifestyle and food and also recent studies pointing out its association with cardiovascular disease and cancer mortality its need of the time to undertake an extensive study on epidemiology, demography and risk factors of gallstone disease. The aim was to study the epidemiological, demographic and risk factor profile in patients harbouring various types of gallbladder calculi.Methods: A cross sectional prospective study was conducted. 100 cholelithiasis patients were undergoing operative procedure at our department.Results: Showed that females had higher incidence of gallstone disease with a ratio of 2:1, mixed gallstone was the predominant type (53%), mean BMI of the study population was 28.03 with SD of 3.61.Conclusions: Women are twice as li...

International Surgery Journal, 2017

Background: Diabetes mellitus is a chronic disorder affecting large segment of population and is ... more Background: Diabetes mellitus is a chronic disorder affecting large segment of population and is a major public health problem.Methods: A prospective cross sectional study of 150 patients conducted in the Department of Surgery at Government Medical College, Kozhikode, Kerala, IndiaResults: Maximum numbers of patients were in the age group of 60-69. Male to female ratio is 3.04:1.50% had duration of diabetes <10 years and 50% had duration ≥10. years. 81 (54%) patients had neuropathy, 53 (35.3%) had PVD, 41 (27.3%) had history of prior foot ulcer, 70 (46.7%) had poor glycemic control (RBS >200 mg/dl) at the time of admission and 44 (29.3%) had history of smoking.Conclusions: Most important risk factors for diabetic foot ulcers were neuropathy (54%), poor glycemic control (46.7%) and PVD (35.3%), diabetic foot requires a comprehensive management.

http://isrctn.org/>, 2012

Background: Adjunctive uterotonic in patients at risk of primary post-partum haemorrhage may redu... more Background: Adjunctive uterotonic in patients at risk of primary post-partum haemorrhage may reduce its incidence. Objective: To compare the effectiveness and safety of adjunctive rectal misoprostol with adjunctive intravenous oxytocin for the prevention of primary post-partum haemorrhage in at risk patients. Materials and methods: A total of 122 patients with risk factors for uterine atony were allocated to receive either 600μg of rectal misoprostol (n= 61) or 20IU of oxytocin infusion (n=61) after routine management of third stage of labour. Post-partum blood loss was measured using differential delivery towel and pad weighing. Results: There was similarity in the estimated post-partum blood loss, with no significant difference in the mean post-partum hematocrit levels between the adjunctive rectal misoprostol group and oxytocin infusion group (P=0.712). There was no difference in the need for additional intervention of uterotonics between the two groups. There were however, higher incidences of shivering and pyrexia among those that received misoprostol compared with the oxytocin group. Conclusion: Rectal misoprostol is as effective and safe as oxytocin when used as an adjunctive uterotonic in preventing primary post-partum haemorrhage in patients with risk factors for uterine atony after active management of third stage of labour.

Revista de Gastroenterología de México, 2014

Objectives: To evaluate total serum calcium (TC) and albumin-corrected calcium (ACC) as prognosti... more Objectives: To evaluate total serum calcium (TC) and albumin-corrected calcium (ACC) as prognostic severity factors in acute pancreatitis (AP). Methods: Ninety-six patients were included in the study. They were diagnosed with AP and admitted to the Hospital Regional de Veracruz within the time frame of January 2010 to December 2012. AP severity was determined through the updated Atlanta Classification (2013). TC and ACC values were measured in the first 24 hours of admittance and the percentages of sensitivity (S), specificity (Sp), positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (LR +), and negative likelihood ratio (LR-) were calculated through ROC curves and contingency tables. Results: In accordance with the updated Atlanta Classification, 70 patients presented with mild AP, 17 with moderately severe AP, and 9 with severe AP. Of the patient total, 61.5% were women, and 69.8% presented with biliary etiology. The maximum TC cutoff point was 7.5 mg/dL, with values of S, 67%; Sp, 82%; PPV, 27%, and NPV, 96%. The maximum ACC cutoff point was 7.5 mg/dL, with values of S, 67%; Sp, 90%; PPV, 40%; NPV, 96%. Both had values similar to those of the Ranson and APACHE II prognostic scales. Conclusions: TC and ACC, measured within the first 24 hours, are useful severity predictors in acute pancreatitis, with sensitivity and predictive values comparable or superior to those of the conventional prognostic scales.