Pankaj Banotra | University of Jammu, Jammu, Jammu and Kashmir, India (original) (raw)
Papers by Pankaj Banotra
Journal of medical science and clinical research, May 3, 2020
RPGN, a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that, ... more RPGN, a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that, if untreated, progresses to end-stage renal disease over weeks to months. Our study aims to study the renal biopsy findings in patients with rapidly progressive glomerulonephritis and its impact on remission outcome. Materials and Methods: A hospital based retrospective study conducted for a period of one year after obtaining ethical clearance. Adults with rapidly progressive glomerulonephritis on the basis of renal biopsy were included. Light microscopy renal biopsy findings at the baseline were obtained and treatment outcome was analyzed as per the biopsy finding. Treatment outcome identified the remission of the patient with 24-hour urine protein <500 mg/day and serum creatinine <1.4 mg/dl. Quantitative variables were compared using Mann-Whitney Test and qualitative variables were correlated using Chi-Square test/Fisher's exact test. A p value of <0.05 was considered statistically significant. Results: In our study, about two-third of patients (63.64%) had showed no response. About one-fourth (25.45%) of patients showed partial remission and 10.91% had complete remission. Three-fourth of patients who achieved remission in study had sclerosis in < 35% of their glomeruli, and between 50-75% of crescents in their glomeruli, suggesting to be a predictor of response, p<0.05 Conclusion: RPGN is an important cause of renal failure. Renal biopsy findings can correlate with the prognosis of the disease and the treatment outcome. An early referral to nephrologist for early diagnosis and treatment is stressed.
International Journal of Advances in Medicine, May 24, 2022
Burn injuries are the most disabling injuries and a major global public health concern. Following... more Burn injuries are the most disabling injuries and a major global public health concern. Following road traffic accidents, falls, and violence, burns are the fourth most common causes of trauma worldwide. Patients suffering from extensive burn injuries may not survive while others suffer from morbidity in terms of long-term hospitalization, multiple surgeries, and rehabilitations. Approximately 90 percent of burns occur in low to middle income countries. 1 One of the aspects of management of burns is the associated burn pain which is very likely the most difficult form of acute pain to treat. The pain is due to the release of inflammatory mediators which cause the stimulation of the pain receptors present in the skin. The pain is further transmitted by A-delta and C fibres leading to the spinal cord dorsal horn. It is estimated that up to 52% of burn patients are suffering from chronic pain. 2 Drug administration involves simple analgesics, non-steroidal anti-inflammatory drugs, opioids, anticonvulsants like pregabalin, gabapentin and antidepressants like amitriptyline for the management of burn pain. 3 non-pharmacological modalities such as relaxation and• cognitive-behavioural therapy is beneficial for pain rehabilitation. 4 Previous epidemiological studies have revealed that burn cases are prevalent all over the country but there is a limited data on the pain management in these patients. 5 The present study was undertaken in the burn unit of the department of surgery with the aim to determine epidemiological, ABSTRACT Background: Burn injuries are a major global public health concern with up to 52% of burn patients suffering from chronic pain. The aim of the study was to asses clinical profile and management of pain in burn patients. Methods: The study was a prospective hospital-based study on a total of 300 patients admitted in burn unit of the department of surgery over a period of two years. BSA burns was determined by Wallace's rule of nine in adults and in children by Lund and Browder chart. Pain was assessed using Wong-Baker FACES pain rating scale. Statistical analysis was done using SPSS program. Results: In the present study, most of the burns i.e., 46.7% were seen in <20 years age group, and more in male (58.7%) subjects. Accidental burns and superficial burns were the most common. There were 113 (53.3%) patients with pain score of 2 followed by 160 (53.3%) with pain score 3, 22 (7.3%) pain score 4 and 5 (1.7%) with pain score of 1. For pain management, 171 (57%) patients were given NSAIDS, 78 (26%) needed opioid and NSAIDs and 51 (17%) needed opioid only. Complications in our studied patients on follow up revealed 29 (9.7%) had PTSD, 22 (7.3%) had post burn contracture, 16 (5.3%) had post burn pain, 15 (5.0%) were having anxiety. Conclusions: Pain in burn victims is present throughout the rehabilitation and so should be dealt with multimodal specialties.
International Journal of Research in Medical Sciences, May 27, 2022
Paroxysmal exercise induced dyskinesias (PED) are rare disorders with recurring episodes of sudde... more Paroxysmal exercise induced dyskinesias (PED) are rare disorders with recurring episodes of sudden involuntary movement disorders precipitated by physical exercise. It had been reported that less than 20% of PED patients carry an SLC2A1 mutation encoding GLUT 1 of whom 49 patients have been identified worldwide We hereby reported a case of twin siblings, 23 year old male with no antecedent other past illness and family history presenting with writer's cramps and paroxysmal exercise induced dyskinesia attributed to milder phenotype of glucose transporter type 1 deficiency with the heterozygous exon-6 SLC2A1 gene mutation. Ketogenic diet in these patients may help in these cases.
International Journal of Research, 2020
Rheumatoid arthritis is a chronic inflammatory systemic disease which is variable in its effects ... more Rheumatoid arthritis is a chronic inflammatory systemic disease which is variable in its effects Although joint disease is the main presentation, there are a number of extra- articular manifestations including subcutaneous nodule formation, vasculitis, inflammatory eye disease and lung disease. ILD is the most common pulmonary manifestation of rheumatoid arthritis lung disease. Our purpose of the study was to assess the pulmonary manifestations of rheumatoid arthritis and its associated risk factors. Materials and Methods: A cross sectional study was conducted in the Postgraduate Department of Medicine at Government Medical College Jammu after obtaining ethical clearance during a period of 1 year. A total of 100 patients of Rheumatoid arthritis who met the ACR EULAR criteria were included. Patients were further evaluated for pulmonary manifestations by physiological (pulmonary function test) and radiological methods (chest X-ray, HRCT chest). Chi-square test was used for comparison ...
International Journal of Advances in Medicine, May 24, 2022
Burn injuries are the most disabling injuries and a major global public health concern. Following... more Burn injuries are the most disabling injuries and a major global public health concern. Following road traffic accidents, falls, and violence, burns are the fourth most common causes of trauma worldwide. Patients suffering from extensive burn injuries may not survive while others suffer from morbidity in terms of long-term hospitalization, multiple surgeries, and rehabilitations. Approximately 90 percent of burns occur in low to middle income countries. 1 One of the aspects of management of burns is the associated burn pain which is very likely the most difficult form of acute pain to treat. The pain is due to the release of inflammatory mediators which cause the stimulation of the pain receptors present in the skin. The pain is further transmitted by A-delta and C fibres leading to the spinal cord dorsal horn. It is estimated that up to 52% of burn patients are suffering from chronic pain. 2 Drug administration involves simple analgesics, non-steroidal anti-inflammatory drugs, opioids, anticonvulsants like pregabalin, gabapentin and antidepressants like amitriptyline for the management of burn pain. 3 non-pharmacological modalities such as relaxation and• cognitive-behavioural therapy is beneficial for pain rehabilitation. 4 Previous epidemiological studies have revealed that burn cases are prevalent all over the country but there is a limited data on the pain management in these patients. 5 The present study was undertaken in the burn unit of the department of surgery with the aim to determine epidemiological, ABSTRACT Background: Burn injuries are a major global public health concern with up to 52% of burn patients suffering from chronic pain. The aim of the study was to asses clinical profile and management of pain in burn patients. Methods: The study was a prospective hospital-based study on a total of 300 patients admitted in burn unit of the department of surgery over a period of two years. BSA burns was determined by Wallace's rule of nine in adults and in children by Lund and Browder chart. Pain was assessed using Wong-Baker FACES pain rating scale. Statistical analysis was done using SPSS program. Results: In the present study, most of the burns i.e., 46.7% were seen in <20 years age group, and more in male (58.7%) subjects. Accidental burns and superficial burns were the most common. There were 113 (53.3%) patients with pain score of 2 followed by 160 (53.3%) with pain score 3, 22 (7.3%) pain score 4 and 5 (1.7%) with pain score of 1. For pain management, 171 (57%) patients were given NSAIDS, 78 (26%) needed opioid and NSAIDs and 51 (17%) needed opioid only. Complications in our studied patients on follow up revealed 29 (9.7%) had PTSD, 22 (7.3%) had post burn contracture, 16 (5.3%) had post burn pain, 15 (5.0%) were having anxiety. Conclusions: Pain in burn victims is present throughout the rehabilitation and so should be dealt with multimodal specialties.
International Journal of Research in Medical Sciences, May 27, 2022
Paroxysmal exercise induced dyskinesias (PED) are rare disorders with recurring episodes of sudde... more Paroxysmal exercise induced dyskinesias (PED) are rare disorders with recurring episodes of sudden involuntary movement disorders precipitated by physical exercise. It had been reported that less than 20% of PED patients carry an SLC2A1 mutation encoding GLUT 1 of whom 49 patients have been identified worldwide We hereby reported a case of twin siblings, 23 year old male with no antecedent other past illness and family history presenting with writer's cramps and paroxysmal exercise induced dyskinesia attributed to milder phenotype of glucose transporter type 1 deficiency with the heterozygous exon-6 SLC2A1 gene mutation. Ketogenic diet in these patients may help in these cases.
International Journal of Research, 2020
RPGN is a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that... more RPGN is a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that, if untreated, progresses to end-stage renal disease over weeks to months. Our study aims to identify factors affecting the treatment outcome in RPGN. Materials and Methods: A hospital based cross sectional study conducted in the Department of Nephrology at Government Medical College, Jammu for a period of one year after obtaining ethical clearance. Adults with rapidly progressive glomerulonephritis on the basis of renal biopsy were included. Routine clinical. biochemical parameters and biopsy findings were analyzed. Primary outcome identified the remission of the patient with 24-hour urine protein <500 mg/day and serum creatinine <1.4 mg/dl. Quantitative variables were compared using Mann-Whitney Test and qualitative variables were correlated using Chi-Square test/Fisher’s exact test. A p value of <0.05 was considered statistically significant. Results: In our study, about two...
International Journal of Research, 2020
Rheumatoid arthritis is a chronic inflammatory systemic disease which is variable in its effects ... more Rheumatoid arthritis is a chronic inflammatory systemic disease which is variable in its effects Although joint disease is the main presentation, there are a number of extra- articular manifestations including subcutaneous nodule formation, vasculitis, inflammatory eye disease and lung disease. ILD is the most common pulmonary manifestation of rheumatoid arthritis lung disease. Our purpose of the study was to assess the pulmonary manifestations of rheumatoid arthritis and its associated risk factors. Materials and Methods: A cross sectional study was conducted in the Postgraduate Department of Medicine at Government Medical College Jammu after obtaining ethical clearance during a period of 1 year. A total of 100 patients of Rheumatoid arthritis who met the ACR EULAR criteria were included. Patients were further evaluated for pulmonary manifestations by physiological (pulmonary function test) and radiological methods (chest X-ray, HRCT chest). Chi-square test was used for comparison ...
Journal of Medical Science And clinical Research, 2020
RPGN, a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that, ... more RPGN, a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that, if untreated, progresses to end-stage renal disease over weeks to months. Our study aims to study the renal biopsy findings in patients with rapidly progressive glomerulonephritis and its impact on remission outcome. Materials and Methods: A hospital based retrospective study conducted for a period of one year after obtaining ethical clearance. Adults with rapidly progressive glomerulonephritis on the basis of renal biopsy were included. Light microscopy renal biopsy findings at the baseline were obtained and treatment outcome was analyzed as per the biopsy finding. Treatment outcome identified the remission of the patient with 24-hour urine protein <500 mg/day and serum creatinine <1.4 mg/dl. Quantitative variables were compared using Mann-Whitney Test and qualitative variables were correlated using Chi-Square test/Fisher's exact test. A p value of <0.05 was considered statistically significant. Results: In our study, about two-third of patients (63.64%) had showed no response. About one-fourth (25.45%) of patients showed partial remission and 10.91% had complete remission. Three-fourth of patients who achieved remission in study had sclerosis in < 35% of their glomeruli, and between 50-75% of crescents in their glomeruli, suggesting to be a predictor of response, p<0.05 Conclusion: RPGN is an important cause of renal failure. Renal biopsy findings can correlate with the prognosis of the disease and the treatment outcome. An early referral to nephrologist for early diagnosis and treatment is stressed.
Journal of medical science and clinical research, May 3, 2020
RPGN, a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that, ... more RPGN, a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that, if untreated, progresses to end-stage renal disease over weeks to months. Our study aims to study the renal biopsy findings in patients with rapidly progressive glomerulonephritis and its impact on remission outcome. Materials and Methods: A hospital based retrospective study conducted for a period of one year after obtaining ethical clearance. Adults with rapidly progressive glomerulonephritis on the basis of renal biopsy were included. Light microscopy renal biopsy findings at the baseline were obtained and treatment outcome was analyzed as per the biopsy finding. Treatment outcome identified the remission of the patient with 24-hour urine protein <500 mg/day and serum creatinine <1.4 mg/dl. Quantitative variables were compared using Mann-Whitney Test and qualitative variables were correlated using Chi-Square test/Fisher's exact test. A p value of <0.05 was considered statistically significant. Results: In our study, about two-third of patients (63.64%) had showed no response. About one-fourth (25.45%) of patients showed partial remission and 10.91% had complete remission. Three-fourth of patients who achieved remission in study had sclerosis in < 35% of their glomeruli, and between 50-75% of crescents in their glomeruli, suggesting to be a predictor of response, p<0.05 Conclusion: RPGN is an important cause of renal failure. Renal biopsy findings can correlate with the prognosis of the disease and the treatment outcome. An early referral to nephrologist for early diagnosis and treatment is stressed.
International Journal of Advances in Medicine, May 24, 2022
Burn injuries are the most disabling injuries and a major global public health concern. Following... more Burn injuries are the most disabling injuries and a major global public health concern. Following road traffic accidents, falls, and violence, burns are the fourth most common causes of trauma worldwide. Patients suffering from extensive burn injuries may not survive while others suffer from morbidity in terms of long-term hospitalization, multiple surgeries, and rehabilitations. Approximately 90 percent of burns occur in low to middle income countries. 1 One of the aspects of management of burns is the associated burn pain which is very likely the most difficult form of acute pain to treat. The pain is due to the release of inflammatory mediators which cause the stimulation of the pain receptors present in the skin. The pain is further transmitted by A-delta and C fibres leading to the spinal cord dorsal horn. It is estimated that up to 52% of burn patients are suffering from chronic pain. 2 Drug administration involves simple analgesics, non-steroidal anti-inflammatory drugs, opioids, anticonvulsants like pregabalin, gabapentin and antidepressants like amitriptyline for the management of burn pain. 3 non-pharmacological modalities such as relaxation and• cognitive-behavioural therapy is beneficial for pain rehabilitation. 4 Previous epidemiological studies have revealed that burn cases are prevalent all over the country but there is a limited data on the pain management in these patients. 5 The present study was undertaken in the burn unit of the department of surgery with the aim to determine epidemiological, ABSTRACT Background: Burn injuries are a major global public health concern with up to 52% of burn patients suffering from chronic pain. The aim of the study was to asses clinical profile and management of pain in burn patients. Methods: The study was a prospective hospital-based study on a total of 300 patients admitted in burn unit of the department of surgery over a period of two years. BSA burns was determined by Wallace's rule of nine in adults and in children by Lund and Browder chart. Pain was assessed using Wong-Baker FACES pain rating scale. Statistical analysis was done using SPSS program. Results: In the present study, most of the burns i.e., 46.7% were seen in <20 years age group, and more in male (58.7%) subjects. Accidental burns and superficial burns were the most common. There were 113 (53.3%) patients with pain score of 2 followed by 160 (53.3%) with pain score 3, 22 (7.3%) pain score 4 and 5 (1.7%) with pain score of 1. For pain management, 171 (57%) patients were given NSAIDS, 78 (26%) needed opioid and NSAIDs and 51 (17%) needed opioid only. Complications in our studied patients on follow up revealed 29 (9.7%) had PTSD, 22 (7.3%) had post burn contracture, 16 (5.3%) had post burn pain, 15 (5.0%) were having anxiety. Conclusions: Pain in burn victims is present throughout the rehabilitation and so should be dealt with multimodal specialties.
International Journal of Research in Medical Sciences, May 27, 2022
Paroxysmal exercise induced dyskinesias (PED) are rare disorders with recurring episodes of sudde... more Paroxysmal exercise induced dyskinesias (PED) are rare disorders with recurring episodes of sudden involuntary movement disorders precipitated by physical exercise. It had been reported that less than 20% of PED patients carry an SLC2A1 mutation encoding GLUT 1 of whom 49 patients have been identified worldwide We hereby reported a case of twin siblings, 23 year old male with no antecedent other past illness and family history presenting with writer's cramps and paroxysmal exercise induced dyskinesia attributed to milder phenotype of glucose transporter type 1 deficiency with the heterozygous exon-6 SLC2A1 gene mutation. Ketogenic diet in these patients may help in these cases.
International Journal of Research, 2020
Rheumatoid arthritis is a chronic inflammatory systemic disease which is variable in its effects ... more Rheumatoid arthritis is a chronic inflammatory systemic disease which is variable in its effects Although joint disease is the main presentation, there are a number of extra- articular manifestations including subcutaneous nodule formation, vasculitis, inflammatory eye disease and lung disease. ILD is the most common pulmonary manifestation of rheumatoid arthritis lung disease. Our purpose of the study was to assess the pulmonary manifestations of rheumatoid arthritis and its associated risk factors. Materials and Methods: A cross sectional study was conducted in the Postgraduate Department of Medicine at Government Medical College Jammu after obtaining ethical clearance during a period of 1 year. A total of 100 patients of Rheumatoid arthritis who met the ACR EULAR criteria were included. Patients were further evaluated for pulmonary manifestations by physiological (pulmonary function test) and radiological methods (chest X-ray, HRCT chest). Chi-square test was used for comparison ...
International Journal of Advances in Medicine, May 24, 2022
Burn injuries are the most disabling injuries and a major global public health concern. Following... more Burn injuries are the most disabling injuries and a major global public health concern. Following road traffic accidents, falls, and violence, burns are the fourth most common causes of trauma worldwide. Patients suffering from extensive burn injuries may not survive while others suffer from morbidity in terms of long-term hospitalization, multiple surgeries, and rehabilitations. Approximately 90 percent of burns occur in low to middle income countries. 1 One of the aspects of management of burns is the associated burn pain which is very likely the most difficult form of acute pain to treat. The pain is due to the release of inflammatory mediators which cause the stimulation of the pain receptors present in the skin. The pain is further transmitted by A-delta and C fibres leading to the spinal cord dorsal horn. It is estimated that up to 52% of burn patients are suffering from chronic pain. 2 Drug administration involves simple analgesics, non-steroidal anti-inflammatory drugs, opioids, anticonvulsants like pregabalin, gabapentin and antidepressants like amitriptyline for the management of burn pain. 3 non-pharmacological modalities such as relaxation and• cognitive-behavioural therapy is beneficial for pain rehabilitation. 4 Previous epidemiological studies have revealed that burn cases are prevalent all over the country but there is a limited data on the pain management in these patients. 5 The present study was undertaken in the burn unit of the department of surgery with the aim to determine epidemiological, ABSTRACT Background: Burn injuries are a major global public health concern with up to 52% of burn patients suffering from chronic pain. The aim of the study was to asses clinical profile and management of pain in burn patients. Methods: The study was a prospective hospital-based study on a total of 300 patients admitted in burn unit of the department of surgery over a period of two years. BSA burns was determined by Wallace's rule of nine in adults and in children by Lund and Browder chart. Pain was assessed using Wong-Baker FACES pain rating scale. Statistical analysis was done using SPSS program. Results: In the present study, most of the burns i.e., 46.7% were seen in <20 years age group, and more in male (58.7%) subjects. Accidental burns and superficial burns were the most common. There were 113 (53.3%) patients with pain score of 2 followed by 160 (53.3%) with pain score 3, 22 (7.3%) pain score 4 and 5 (1.7%) with pain score of 1. For pain management, 171 (57%) patients were given NSAIDS, 78 (26%) needed opioid and NSAIDs and 51 (17%) needed opioid only. Complications in our studied patients on follow up revealed 29 (9.7%) had PTSD, 22 (7.3%) had post burn contracture, 16 (5.3%) had post burn pain, 15 (5.0%) were having anxiety. Conclusions: Pain in burn victims is present throughout the rehabilitation and so should be dealt with multimodal specialties.
International Journal of Research in Medical Sciences, May 27, 2022
Paroxysmal exercise induced dyskinesias (PED) are rare disorders with recurring episodes of sudde... more Paroxysmal exercise induced dyskinesias (PED) are rare disorders with recurring episodes of sudden involuntary movement disorders precipitated by physical exercise. It had been reported that less than 20% of PED patients carry an SLC2A1 mutation encoding GLUT 1 of whom 49 patients have been identified worldwide We hereby reported a case of twin siblings, 23 year old male with no antecedent other past illness and family history presenting with writer's cramps and paroxysmal exercise induced dyskinesia attributed to milder phenotype of glucose transporter type 1 deficiency with the heterozygous exon-6 SLC2A1 gene mutation. Ketogenic diet in these patients may help in these cases.
International Journal of Research, 2020
RPGN is a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that... more RPGN is a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that, if untreated, progresses to end-stage renal disease over weeks to months. Our study aims to identify factors affecting the treatment outcome in RPGN. Materials and Methods: A hospital based cross sectional study conducted in the Department of Nephrology at Government Medical College, Jammu for a period of one year after obtaining ethical clearance. Adults with rapidly progressive glomerulonephritis on the basis of renal biopsy were included. Routine clinical. biochemical parameters and biopsy findings were analyzed. Primary outcome identified the remission of the patient with 24-hour urine protein <500 mg/day and serum creatinine <1.4 mg/dl. Quantitative variables were compared using Mann-Whitney Test and qualitative variables were correlated using Chi-Square test/Fisher’s exact test. A p value of <0.05 was considered statistically significant. Results: In our study, about two...
International Journal of Research, 2020
Rheumatoid arthritis is a chronic inflammatory systemic disease which is variable in its effects ... more Rheumatoid arthritis is a chronic inflammatory systemic disease which is variable in its effects Although joint disease is the main presentation, there are a number of extra- articular manifestations including subcutaneous nodule formation, vasculitis, inflammatory eye disease and lung disease. ILD is the most common pulmonary manifestation of rheumatoid arthritis lung disease. Our purpose of the study was to assess the pulmonary manifestations of rheumatoid arthritis and its associated risk factors. Materials and Methods: A cross sectional study was conducted in the Postgraduate Department of Medicine at Government Medical College Jammu after obtaining ethical clearance during a period of 1 year. A total of 100 patients of Rheumatoid arthritis who met the ACR EULAR criteria were included. Patients were further evaluated for pulmonary manifestations by physiological (pulmonary function test) and radiological methods (chest X-ray, HRCT chest). Chi-square test was used for comparison ...
Journal of Medical Science And clinical Research, 2020
RPGN, a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that, ... more RPGN, a type of nephritic syndrome, accompanied by extensive glomerular crescent formation that, if untreated, progresses to end-stage renal disease over weeks to months. Our study aims to study the renal biopsy findings in patients with rapidly progressive glomerulonephritis and its impact on remission outcome. Materials and Methods: A hospital based retrospective study conducted for a period of one year after obtaining ethical clearance. Adults with rapidly progressive glomerulonephritis on the basis of renal biopsy were included. Light microscopy renal biopsy findings at the baseline were obtained and treatment outcome was analyzed as per the biopsy finding. Treatment outcome identified the remission of the patient with 24-hour urine protein <500 mg/day and serum creatinine <1.4 mg/dl. Quantitative variables were compared using Mann-Whitney Test and qualitative variables were correlated using Chi-Square test/Fisher's exact test. A p value of <0.05 was considered statistically significant. Results: In our study, about two-third of patients (63.64%) had showed no response. About one-fourth (25.45%) of patients showed partial remission and 10.91% had complete remission. Three-fourth of patients who achieved remission in study had sclerosis in < 35% of their glomeruli, and between 50-75% of crescents in their glomeruli, suggesting to be a predictor of response, p<0.05 Conclusion: RPGN is an important cause of renal failure. Renal biopsy findings can correlate with the prognosis of the disease and the treatment outcome. An early referral to nephrologist for early diagnosis and treatment is stressed.