Mohamed Atia Salman Elbandy | University of Jazan (original) (raw)

Papers by Mohamed Atia Salman Elbandy

Molecules

Functional foods include enhanced, enriched, fortified, or whole foods that impart health benefit... more Functional foods include enhanced, enriched, fortified, or whole foods that impart health benefits beyond their nutritional value, particularly when consumed as part of a varied diet on a regular basis at effective levels. Marine sources can serve as the sources of various healthy foods and numerous functional food ingredients with biological effects can be derived from these sources. Microalgae, macroalgae, crustaceans, fungi, bacteria fish, and fish by-products are the most common marine sources that can provide many potential functional food ingredients including phenolic compounds, proteins and peptides, and polysaccharides. Neuroinflammation is closely linked with the initiation and progression of various neurodegenerative diseases, including Alzheimer’s disease, Huntington’s disease, and Parkinson’s disease. Activation of astrocytes and microglia is a defense mechanism of the brain to counter damaged tissues and detrimental pathogens, wherein their chronic activation triggers ...

Bulletin of the Korean Chemical Society, 2009

Milled mushroom micelles grown on sorghum grains (MSG) or on wheat grains (MWG) were evaluated as... more Milled mushroom micelles grown on sorghum grains (MSG) or on wheat grains (MWG) were evaluated as a partial substitute for wheat flour in pan bread and biscuit production. The rheological properties of flour dough and baking quality properties (physical, chemical, protein content, color and sensory characteristics in pan bread and biscuit) of wheat flour or milled mushroom micelles (MSG or MWG) and their blends were examined. Wheat flour was partially replaced by milled mushroom micelles grew on sorghum or wheat grains in ratios of 15, 30, and 45% in pan bread and biscuit blends. Water absorption, dough development time (DDT) and dough weakening increased but mixing tolerance index (MTI) and dough stability decreased relatively marginal by milled mushroom micelles at the level of 15 and 30%. Greater effects were observed on the mixing tolerance index values (MTI) in biscuit. MTI increased in products treated with milled mushroom micelles with increasing the level from 15% to 30%. Ba...

In the present study, pomegranate seed oils (PSO) were extracted and analyzed for their fatty aci... more In the present study, pomegranate seed oils (PSO) were extracted and analyzed for their fatty acid profiles and total tocopherols. The defatted pomegranate seed residue (PSR) was evaluated for its total phenolic and scavenging capacities against DPPH. Dietary effect of pomegranate seed oil, defatted seed residue and their mixture (PSOR) on hypercholesterolemic rats was investigated. The results revealed that, pomegranate seed oil was rich in polyunsaturated fatty acid (88.4%) and total tocopherols (905.5 µg/100g). Meanwhile, the pomegranate seed residue contained amount of total phenolics (14.8 mg/g) and exhibited high scavenging activity (98.2%). After 28 days of feeding period, atherogenic rats group (AC) revealed an increasing in level of total cholesterol, triglyceride, low density lipoprotein cholesterol (LDL-C), risk ratio, atherogenic index and lipid peroxidation compared with normal control rats group (NC). Supplemented diet with 5% pomegranate seed oil, 10% pomegranate seed...

ChemInform, 2009

Skip to Main Content. ...

Research Journal of Pharmaceutical, Biological and Chemical Sciences

Three strains of Trichoderma sp. were screened for β-glucosidase activity and their potential for... more Three strains of Trichoderma sp. were screened for β-glucosidase activity and their potential for the breakdown of isoflavone glucosides to the biologically active aglycones in defatted soy bean meal. The main flavonoid products of fermentation process were evaluated by qualitative and quantitative HPLC analysis. Also, the production of volatile compounds in both the crude soy meal (CSM) and defatted soy meal (DSM) cultured by Trichoderma harzianam F.555 were determined by GC-MS. Isoflavones in defatted soy meal fermented by Trichoderma viride, F-516 or T. harzianam F-555 or T. reesei F-417 at 37 °C for 48 h were determined. Daidzein and genistein aglycones concentrations were significantly increased after fermentation to 162% and 362.4 % for T. reesei; 151.3% and 944 % for T. harzianam and up to 80.6% and 711 % for T. viride, respectively. Results showed that fermented defatted soy meal by T. harzianam F-555 T. viride F-516 and T. reesei F-417 increased levels of bioactive genistei...

Helvetica Chimica Acta

Five new triterpene saponins 1–5 were isolated from the roots of Muraltia ononidifolia E. Mey alo... more Five new triterpene saponins 1–5 were isolated from the roots of Muraltia ononidifolia E. Mey along with the two known saponins 3-O-[O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]medicagenic acid 28-[O-β-D-xylopyranosyl-(1→4)-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl] ester and 3-O-(β-D-glucopyranosyl)medicagenic acid 28-[O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl] ester (medicagenic acid=(4α,2β,3β)-2,3-dihydroxyolean-12-ene-23,28-dioic acid). Their structures were elucidated mainly by spectroscopic experiments, including 2D-NMR techniques, as 3-O-(β-D-glucopyranosyl)medicagenic acid 28-[O-β- D-apiofuranosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl] ester (1), 3-O-(β-D-glucopyranosyl)medicagenic acid 28-{[O-β-D-xylopyranosyl-(1→4)-O-[β-D-apiofuranosyl-(1→3)]-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl} ester (2), 3-O-[O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]medicagenic acid 28-{O-β-D-xylopyranosyl-(1→4)-O-[β-D-apiofuran...

Phytochemistry Letters, 2014

ABSTRACT Raw lupin seeds flour is increasingly used as a food ingredient because of its nutrition... more ABSTRACT Raw lupin seeds flour is increasingly used as a food ingredient because of its nutritional and functional values. This study is considered to be the first phytochemical investigation of the flavonoids of the methanol (MeOH) fraction of Lupinus termis seeds. The study led to the isolation of two new di-C-glycoside flavones, apigenin-6-C-beta-D-glucopyranosyl-8-C-[beta-D-apiofuranosyl-(1 -> 2)]-beta-glucopyranoside (1), apigenin-6-C-beta-D-glucopyranosyl-8-C-[alpha-L-rhamnopyranosyl-(1 -> 2)]-beta-glucopyranoside (2), together with one known flavone di-C-glycoside, apigenin-7-O-beta-D-apiofuranosyl-6,8-di-C-beta-glucopyranoside (3). These compounds are considered to have potential functional properties. The isolated compounds may contribute to the yellow color of raw lupin seeds flour-based products. It may also be used as natural yellow color in food or pharmaceutical products and as a dietary supplement product. These rare flavones were purified by using semi-preparative HPLC. The structures of the isolated compounds were elucidated on the basis of extensive spectroscopic methods, 1D and 2D nuclear magnetic resonance techniques, FAB (Fast Atom Bombardment) - mass spectrometry and acid hydrolysis.

Journal of Natural Products

Helvetica Chimica Acta, 2007

Helvetica Chimica Acta, 2003

ABSTRACT Eight new acylated preatroxigenin saponins 1–8 were isolated as four inseparable mixture... more ABSTRACT Eight new acylated preatroxigenin saponins 1–8 were isolated as four inseparable mixtures of the trans- and cis-4-methoxycinnamoyl derivatives, atroximasaponins A1/A2 (1/2), B1/B2 (3/4), C1/C2 (5/6) and D1/D2 (7/8) from the roots of Atroxima congolana. These compounds are the first examples of triterpene saponins containing preatroxigenin (=(2β,3β,4α,22β)-2,3,22,27-tetrahydroxyolean-12-ene-23,28-dioic acid as aglycone. Their structures were elucidated on the basis of extensive 1D- and 2D-NMR studies and FAB-MS as 3-O(β-D-glucopyranosyl)preatroxigenin 28-{O-β-D-xylopyranosyl-(1→4)-O-α-L-rhamnopyranosyl-(1→2)-O-[O-β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl-(1→3)]-4-O-(trans-4-methoxycinnamoyl)-β-D-fucopyranoyl} ester (1) and its cis-isomer 2, 3-O-(β-D-glucopyranosyl)preatroxigenin 28-{O-β-D-xylopyranosyl-(1→4)-O-α-L-rhamnopyranosyl-(1→ 2)-O-[O-6-O-acetyl-β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl-(1→3)]-4-O-(trans- 4-methoxycinnamoyl)-β-D-fucopyranosyl} ester (3) and its cis-isomer 4, 3-O-(β-D-glucopyranosyl)preatroxigenin 28-{O-β-D-xylopyranosyl-(1→4)-O-[β-D-apiofuranosyl-(1→3)]-O-α-L-rhamnopyranosyl-(1→2)-O-[O-6- O-acetyl-β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl-(1→3)]-4-O-(trans-4-methoxycinnamoyl)-β-D-fucopyranoyl} ester (5) and its cis-isomer 6, 3-O-(β-D-glucopyranosyl)preatroxigenin 28-{O-β-D-xylopyranosyl-(1→4)-O-[β-D-apiofuranosyl-(1→3)]-O-α-L-rhamnopyranosyl-(1→2)-O-[O-β-D-xylopyranosyl-(1→3)-β-D-glucopyranosyl-(1→3)]-4-O-(trans-4-methoxycinnamoyl)-β-D-fucopyranosyl ester (7) and its cis-isomer 8.

Helvetica Chimica Acta, 2004

ABSTRACT Six new acylated bisdesmosidic triterpene glycosides 1–6 were isolated from the roots of... more ABSTRACT Six new acylated bisdesmosidic triterpene glycosides 1–6 were isolated from the roots of Muraltia heisteria (L.) DC., as three inseparable mixtures 1/2, 3/4, and 5/6 of the (E)- and (Z)-3,4,5-trimethoxycinnamoyl derivatives. The compound pair 1/2 along with four known saponins were also isolated from the roots of Muraltia satureioides DC. Their structures were elucidated mainly by spectroscopic experiments including 2D-NMR techniques as 3-O-(β-D-glucopyranosyl)presenegenin 28-{O-β-D-apiofuranosyl-(1→3)-O-[β-D-xylopyranosyl-(1→4)]-O-α-L-rhamnopyranosyl-(1→2)-O-[6-O-acetyl-β-D-galactopyranosyl-(1→3)]-4-O-[(E)-3,4,5-trimethoxycinnamoyl]-β-D-fucopyranosyl} ester (1) and its (Z)-isomer 2, 3-O-(β-D-glucopyranosyl)presenegenin 28-{O-6-O-acetyl-β-D-galactopyranosyl-(1→3)-O-[3-O-acetyl-α-L-rhamnopyranosyl-(1→2)]-4-O-[(E)-3,4,5-trimethoxycinnamoyl]-β-D-fucopyranosyl} ester (3) and its (Z)-isomer 4, and 3-O-(β-D-glucopyranosyl)presenegenin 28-{O-3-O-acetyl-α-L-rhamnopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-4-O-[(E)-3,4,5-trimethoxycinnamoyl]-β-D-fucopyranosyl} ester (5) and its (Z)-isomer 6, respectively.

European Food Research and Technology, 2014

Biochemical Systematics and Ecology, 2004

Constituents of the rhizome of Homalomena occulta Mohamed Elbandy , Holger Lerche , Hildebert Wag... more Constituents of the rhizome of Homalomena occulta Mohamed Elbandy , Holger Lerche , Hildebert Wagner , Marie-Aleth Lacaille-Dubois a, a Laboratoire de Pharmacognosie, Unite de Molecules d’Interet Biologique (UMIB EA 3660), Faculte de Pharmacie, Universite de Bourgogne, 7 Bd Jeanne d’Arc, BP 87900, 21079 Dijon Cedex, France b Department of Pharmacy, Centre of Pharmaresearch, Butenandtstr. 5-13, University of Munich, 81377 Munich, Germany

CHEMICAL & PHARMACEUTICAL BULLETIN, 2007

Journal of Natural Products, 2008

International Journal of Science and Research (IJSR)

Bio-preservation, the use of natural antimicrobial compounds, a safe and ecological approach to i... more Bio-preservation, the use of natural antimicrobial compounds, a safe and ecological approach to increase the shelf life and enhance food safety, has gained increasing attention in recent years. The antibacterial activity of aqueous root extracts of Salvadora persica L. were evaluated on the microbial growth of different bacterial strains by determining inhibition ratio. In addition, these aqueous extracts were tested as natural preservative agents in chicken burger by estimating the total bacterial count and sensory quality characteristics of products. The extracts were prepared by soaking miswak's root in distilled water (10g/100ml, w/v) for 24 and 48 hrs. All tested extracts exhibited effectiveness for preventing growth of some spoilage bacteria, but the 48 hrs extract showed the strongest inhibitory effects against the bacterial growth of (Streptococus mitis, Streptococcus salivarius, Streptococcus mutans, Staphylococcus aureus, Bacillus sabtilis, Pseudomonas earuginosa, E. c...

Phytochemistry Letters, 2013

ABSTRACT In our continuing effort to discover new drug leads from Red Sea marine organisms, a sam... more ABSTRACT In our continuing effort to discover new drug leads from Red Sea marine organisms, a sample of the marine cyanobacterium Moorea producens (previously Lyngbya majuscula) was investigated. Bioassay-directed purification of a tumor cell-growth inhibitory fraction of the organic extract of the Red Sea cyanobacterium afforded a new compound, malyngamide 4 (1), together with five previously reported compounds, malyngamide A (2) and B (3), (S)-7-methoxytetradec-4(E)-enoic acid (lyngbic acid, 4), aplysiatoxin (5) and debromoaplysiatoxin (6). Assignment of the planar structures of these compounds was based on extensive analysis of one- and two-dimensional NMR spectra and high-resolution mass spectrometric data. The isolated compounds were evaluated for their inhibitory activity against three cancer cell lines. In addition, the antibacterial activity of the compounds against Mycobacterium tuberculosis H37Rv ATCC 27294 (H37Rv) was evaluated. Lyngbic acid (4) was the most active against M. tuberculosis, while malyngamides 4 (1) and B (3) moderately inhibited the cancer cell lines. The other compounds were deemed inactive at the test concentrations.

ABSTRACT The edible portion of sea cucumber, body walls, is a source of natural bioactive compoun... more ABSTRACT The edible portion of sea cucumber, body walls, is a source of natural bioactive compounds. Triterpene saponins are the main chemical constituents of potential interest for the body health and food industry in sea cucumber. Moreover, the importance of saponins is increasing in food, cosmetics, and pharmaceutical sectors because of their physicochemical (surfactant) properties and mounting evidence on their biological activity. Although, sea cucumber (Bohadschia cousteaui) has high antifungal, antiprotozoal and anticancer activities, no chemical study of its secondary metabolites has been previously realized.The present work deals with the extraction, isolation and structure elucidation of twenty one triterpene glycosides present in a methanol / methylene chloride extract of the body walls of Bohadschia cousteaui. Ten new saponins called coustesides A (1), B (3), C (9), D (10), E (11), F (12), G (15), H (16), I (17), and J (18), together with eleven known glycosides were isolated by reversed phase semi-preparative HPLC. The structures of these compounds were mainly determined by spectroscopic methods including Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (Ms) techniques. The isolated compounds were usually of the lanosterol-type with a 18(20)-lactone and sugar chain of up to six non-sulfated monosaccharide units generally linked to the C-3 of the aglycon, which are composed of D-xylose, D-quinovose, D-glucose and 3-O-methyl-D-glucose. Most of isolated compounds showed good antifungal activity against candida albicans. Sea cucumber (Bohadschia cousteaui) is a rich source of biologically active saponins. Therefore, sea cucumbers are eaten for their therapeutic values as nutraceutical food than for their seafood taste. Key words: Bohadschia cousteaui, Sea cucumber, Sea food, Saponins, Holostane-type triterpene, Cousteosides, Bioactive compounds.