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Papers by Laura martinez

Research paper thumbnail of Assessment of EULAR/ACR-2019, SLICC-2012 and ACR-1997 Classification Criteria in SLE with Longstanding Disease

Journal of Clinical Medicine, 2021

Background: Different classification criteria for systemic lupus erythematosus (SLE) have been la... more Background: Different classification criteria for systemic lupus erythematosus (SLE) have been launched over the years. Our aim was to evaluate the performance of the EULAR/ACR-2019, SLICC-2012 and ACR-1997 classification criteria in a cohort of SLE patients with longstanding disease. Methods: Descriptive observational study in 79 patients with established and longstanding SLE. The three classification criteria sets were applied to those patients. Results: Of the 79 patients, 70 were women (88.6%), with a mean age of 51.8 ± 14 years and a mean disease duration of 15.2 ± 11.5 years. The sensitivity of the different criteria were: 51.9%, 87.3% and 86.1% for ACR-1997, SLICC-2012 and EULAR/ACR-2019, respectively. In total, 68 out of 79 patients (53.7%) met all three classification criteria; 11.4% did not meet any classification criteria and were characterized by low SLEDAI (0.6 ± 0.9), low SLICC/ACR Damage Index (0.88 ± 0.56) and fulfilling only skin domains, antiphospholipid antibodies...

Research paper thumbnail of A Novel Mutation in the TAP2 Gene in Bare Lymphocyte Syndrome: Association With Metastatic Cutaneous Squamous Cell Carcinoma

Archives of Dermatology, 2010

A 39-year-old woman presented with a 30-year clinical history of ulcers on the right leg appearin... more A 39-year-old woman presented with a 30-year clinical history of ulcers on the right leg appearing after local trauma (Figure 1). She had similar lesions on the left leg. During late childhood, she had recurrent sinobronchial infections that evolved to bronchiectasis. Analysis of biopsy ...

Research paper thumbnail of Assessment of EULAR/ACR-2019, SLICC-2012 and ACR-1997 Classification Criteria in SLE with Longstanding Disease

Journal of Clinical Medicine, 2021

Background: Different classification criteria for systemic lupus erythematosus (SLE) have been la... more Background: Different classification criteria for systemic lupus erythematosus (SLE) have been launched over the years. Our aim was to evaluate the performance of the EULAR/ACR-2019, SLICC-2012 and ACR-1997 classification criteria in a cohort of SLE patients with longstanding disease. Methods: Descriptive observational study in 79 patients with established and longstanding SLE. The three classification criteria sets were applied to those patients. Results: Of the 79 patients, 70 were women (88.6%), with a mean age of 51.8 ± 14 years and a mean disease duration of 15.2 ± 11.5 years. The sensitivity of the different criteria were: 51.9%, 87.3% and 86.1% for ACR-1997, SLICC-2012 and EULAR/ACR-2019, respectively. In total, 68 out of 79 patients (53.7%) met all three classification criteria; 11.4% did not meet any classification criteria and were characterized by low SLEDAI (0.6 ± 0.9), low SLICC/ACR Damage Index (0.88 ± 0.56) and fulfilling only skin domains, antiphospholipid antibodies...

Research paper thumbnail of A Novel Mutation in the TAP2 Gene in Bare Lymphocyte Syndrome: Association With Metastatic Cutaneous Squamous Cell Carcinoma

Archives of Dermatology, 2010

A 39-year-old woman presented with a 30-year clinical history of ulcers on the right leg appearin... more A 39-year-old woman presented with a 30-year clinical history of ulcers on the right leg appearing after local trauma (Figure 1). She had similar lesions on the left leg. During late childhood, she had recurrent sinobronchial infections that evolved to bronchiectasis. Analysis of biopsy ...

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