Microarray Analysis of Lipopolysaccharide Potentiation of Trovafloxacin-Induced Liver Injury in Rats Suggests a Role for Proinflammatory Chemokines and Neutrophils (original) (raw)
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Research ArticleTOXICOLOGY
Jeffrey F. Waring, Michael J. Liguori, James P. Luyendyk, Jane F. Maddox, Patricia E. Ganey, Robert F. Stachlewitz, Colin North, Eric A. G. Blomme and Robert A. Roth
Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1080-1087; DOI: https://doi.org/10.1124/jpet.105.096347
Jeffrey F. Waring
Department of Cellular and Molecular Toxicology, Abbott Laboratories, Abbott Park, Illinois (J.F.W., M.J.L., E.A.G.B.); Abbott Bioresearch Center, Worcester, Massachusetts (R.F.S.); and Department of Pharmacology and Toxicology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan (J.P.L., J.F.M., P.E.G., C.N., R.A.R.)
Michael J. Liguori
Department of Cellular and Molecular Toxicology, Abbott Laboratories, Abbott Park, Illinois (J.F.W., M.J.L., E.A.G.B.); Abbott Bioresearch Center, Worcester, Massachusetts (R.F.S.); and Department of Pharmacology and Toxicology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan (J.P.L., J.F.M., P.E.G., C.N., R.A.R.)
James P. Luyendyk
Department of Cellular and Molecular Toxicology, Abbott Laboratories, Abbott Park, Illinois (J.F.W., M.J.L., E.A.G.B.); Abbott Bioresearch Center, Worcester, Massachusetts (R.F.S.); and Department of Pharmacology and Toxicology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan (J.P.L., J.F.M., P.E.G., C.N., R.A.R.)
Jane F. Maddox
Department of Cellular and Molecular Toxicology, Abbott Laboratories, Abbott Park, Illinois (J.F.W., M.J.L., E.A.G.B.); Abbott Bioresearch Center, Worcester, Massachusetts (R.F.S.); and Department of Pharmacology and Toxicology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan (J.P.L., J.F.M., P.E.G., C.N., R.A.R.)
Patricia E. Ganey
Department of Cellular and Molecular Toxicology, Abbott Laboratories, Abbott Park, Illinois (J.F.W., M.J.L., E.A.G.B.); Abbott Bioresearch Center, Worcester, Massachusetts (R.F.S.); and Department of Pharmacology and Toxicology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan (J.P.L., J.F.M., P.E.G., C.N., R.A.R.)
Robert F. Stachlewitz
Department of Cellular and Molecular Toxicology, Abbott Laboratories, Abbott Park, Illinois (J.F.W., M.J.L., E.A.G.B.); Abbott Bioresearch Center, Worcester, Massachusetts (R.F.S.); and Department of Pharmacology and Toxicology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan (J.P.L., J.F.M., P.E.G., C.N., R.A.R.)
Colin North
Department of Cellular and Molecular Toxicology, Abbott Laboratories, Abbott Park, Illinois (J.F.W., M.J.L., E.A.G.B.); Abbott Bioresearch Center, Worcester, Massachusetts (R.F.S.); and Department of Pharmacology and Toxicology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan (J.P.L., J.F.M., P.E.G., C.N., R.A.R.)
Eric A. G. Blomme
Department of Cellular and Molecular Toxicology, Abbott Laboratories, Abbott Park, Illinois (J.F.W., M.J.L., E.A.G.B.); Abbott Bioresearch Center, Worcester, Massachusetts (R.F.S.); and Department of Pharmacology and Toxicology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan (J.P.L., J.F.M., P.E.G., C.N., R.A.R.)
Robert A. Roth
Department of Cellular and Molecular Toxicology, Abbott Laboratories, Abbott Park, Illinois (J.F.W., M.J.L., E.A.G.B.); Abbott Bioresearch Center, Worcester, Massachusetts (R.F.S.); and Department of Pharmacology and Toxicology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan (J.P.L., J.F.M., P.E.G., C.N., R.A.R.)
In this issue
Research ArticleTOXICOLOGY
Microarray Analysis of Lipopolysaccharide Potentiation of Trovafloxacin-Induced Liver Injury in Rats Suggests a Role for Proinflammatory Chemokines and Neutrophils
Jeffrey F. Waring, Michael J. Liguori, James P. Luyendyk, Jane F. Maddox, Patricia E. Ganey, Robert F. Stachlewitz, Colin North, Eric A. G. Blomme and Robert A. Roth
Journal of Pharmacology and Experimental Therapeutics March 1, 2006, 316 (3) 1080-1087; DOI: https://doi.org/10.1124/jpet.105.096347
Research ArticleTOXICOLOGY
Microarray Analysis of Lipopolysaccharide Potentiation of Trovafloxacin-Induced Liver Injury in Rats Suggests a Role for Proinflammatory Chemokines and Neutrophils
Jeffrey F. Waring, Michael J. Liguori, James P. Luyendyk, Jane F. Maddox, Patricia E. Ganey, Robert F. Stachlewitz, Colin North, Eric A. G. Blomme and Robert A. Roth
Journal of Pharmacology and Experimental Therapeutics March 1, 2006, 316 (3) 1080-1087; DOI: https://doi.org/10.1124/jpet.105.096347