Samiron Sana | Jessore University of Science & Technology (original) (raw)

Papers by Samiron Sana

Background The COVID-19 is the greatest catastrophe of the 21st century that ravaged health, econ... more Background The COVID-19 is the greatest catastrophe of the 21st century that ravaged health, economy, and everyday life. Over 90% of the infected individuals in Bangladesh took home treatments following various approaches and consuming different medications. The study aims to identify the recovery measures and the medications used by COVID-19 patients at home. Methods An online-based, cross-sectional survey was conducted between 5 October 2020 and 5 January 2021 among the COVID-19 patients who did not seek care from hospitals and recovered at home. Participants from all the administrative divisions of Bangladesh were recruited via social media. After obtaining consent, subjects were enrolled to complete the questionnaire that included questions on demographic characteristics, clinical itinerary, non-pharmacological and pharmacological approaches. Results Of the 241 respondents, the majority were males (64.3%), aged 21-30 years (42.3%), and urban residents (65.6%). Fever (92.5%), cou...

The Pharma Innovation Journal, 2017

Thyroid disease is a common endocrine disorder resulting from their impaired activity at tissue l... more Thyroid disease is a common endocrine disorder resulting from their impaired activity at tissue level. Congenital hypothyroidism and environmental thyroiditis are two major concern now-a-days. Congenital hypothyroidism is broadly classified into Primary hypothyroidism, secondary hypothyroidism, peripheral hypothyroidism, syndromic hypothyroidism and transient congenital hypothyroidism. Factors affecting congenital hypothyroidism may include thyroid dyshormonogenesis, thyroid dysgenesis, resistance to TH binding, defects in T3 and T4 release or even genetic factor. Factors that increase environmental thyroid disease risk include radiation exposure, both from nuclear fallout and medical radiation, increased iodine intake, as well as several contaminants in the environment that influence the thyroid. In Bangladesh the overall state of thyroid disease is greatly influenced by gender and diseases like diabetes. Necessary steps should be taken to raise awareness among mass people about Hypothyroidism and enlighten them to make stand against this disease.

The ongoing respiratory disease pandemic COVID-19 caused by a newly emerging highly infectious vi... more The ongoing respiratory disease pandemic COVID-19 caused by a newly emerging highly infectious virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is aggravating the world’s health, economy and regular life. This unprecedented respiratory outbreak has already infected more than 43 million individuals and taken more than 1.1 million lives. The habitation of over 21% of the world’s population- the SAARC region is also susceptible to COVID-19 and comprises of more than 20% of the total infected cases. Demographic analysis showed that males and younger populations are mostly infected in South Asian countries. Similar genomic variations were observed in the countries such as variations in the ORF1ab, ORF1a, ORF3a and S genes were largely seen. As no effective treatment strategy hasn’t developed yet, only timely testing and tracing can mitigate the loss from the disease which led the way to the development of alternate screening methods with higher efficiency and timely res...

Objectives: The objective of this study was to evaluate the level of lipid profile and serum crea... more Objectives: The objective of this study was to evaluate the level of lipid profile and serum creatinine in patients with diabetes mellitus to correlate the lipid profile abnormalities with serum creatinine levels in diabetic patients. Methods: This cross sectional health survey was carried out with a self-designed standard questionnaire by manual data collection over a six months period (12.09.2015 to 10.04.2016) at three adjacent cities Jessore Sadar, Jhikargacha and Chowgacha upazila respectively. The data were collected from the patients prescription, diagnostic reports and by directly interviewing the patients who were treated as either type 1 or type 2 diabetic 235 fasting patients during the study period. Descriptive statistics were applied to the collected data and analyzed using Microsoft Excel software. Results: In our current survey, the average levels of HDL, LDL, TC, TG and Serum creatinine of investigated patients were observed with respect to their individual groups as...

A mushroom (or toadstool) is the fleshy, spore-bearing fruiting body of a fungus, typically produ... more A mushroom (or toadstool) is the fleshy, spore-bearing fruiting body of a fungus, typically produced above ground on soil or on its food source. Mushrooms have been consumed since earliest history; ancient Greeks believed that mushrooms provided strength for warriors in battle, and the Romans perceived them as the “Food of the Gods.” For centuries, the Chinese culture has treasured mushrooms as a health food, an “elixir of life”. For thousands of years it has been used as a potential source of medication and also a nutrient notable supplier of fibres, proteins, vitamins etc. Many mushroom species produce secondary metabolites that can be severely toxic and may cause psychosis. Although there are only a small number of deadly species, several others can cause particularly severe and unpleasant symptoms. This review includes a brief discussion on medicinal & toxic mushrooms and also highlights on some cultivated mushrooms in Bangladesh.

International Journal of Biomedical and Advance Research, 2017

Journal of Pharmaceutical Research International, 2018

Objective: Traditionally Ficus hispida is used as a palliative for pain, inflammation, diabetes, ... more Objective: Traditionally Ficus hispida is used as a palliative for pain, inflammation, diabetes, fever and neurological disorders. The present study set out to evaluate the antinociceptive, anti-pyretic and anti-inflammatory activity of the methanolic extract of Ficus hispida leaves (MFHL). Methods: Pithy dried leaves of Ficus hispida were extracted with sufficient amount of pure methanol. The antinociceptive activity of MFHL was evaluated by using formalin induced paw licking, acetic acid-induced writhing, tail immersion and hot plate methods in Swiss albino mice. Its anti-pyretic activity was evaluated by Brewer's yeast-induced pyrexia test. And anti-inflammatory activity was assessed by using xylene-induced ear edema test. Results: The crude extract was found to have significant (p<0.05, vs. control) analgesic activity at the oral dose of 200 & 400 mg/kg b. wt., in the tested animals. Extract at dose of 200 mg/kg and 400

International Journal of Food Science and Biotechnology, 2019

This study was conducted to estimate the concentrations of 8 trace elements including (Mn, Fe, Cu... more This study was conducted to estimate the concentrations of 8 trace elements including (Mn, Fe, Cu, Zn, Ni, Ar, Cr, and Pb) and 4 anti-nutritional factors including (saponins, oxalates, phytate, and cyanogenic glycosides) in leaves and stems from Moringa oleifera. The concentrations in samples analyzed were found to be in the range of 0.88-1.88 mg/kg for Mn, 11.95-25.25 mg/kg for Fe, 0.35-1.22 mg/kg for Cu, 6.92-17.96 mg/kg for Zn, 0.03-0.07 mg/kg for Ni, 0.955-1.45 mg/kg for Cr and 0.564-0.85 mg/kg for Pb. However, Arsenic was not detected in all the samples analyzed. As for the anti-nutritional factors, the concentrations in samples analyzed were found to be in the range of 111.35-123.42 mg/kg for saponins, 69.5-509.4 mg/kg for oxalates, and 0.38-0.156 mg/kg for phytate and 316.95-325.27 mg/kg for cyanogenic glycosides. The values of all these elements were found significantly below the recommended maximum tolerable guidelines level proposed by WHO/FAO except for lead (Pb), Pb was found slightly higher than the recommended limit as described. Our findings of this study reveal that most of the trace elements found in M. oleifera are below the recommended maximum tolerable limits; therefore it is safe for both human and animal consumption as well.

The mortality related to snake bites is an extreme public health problem because the estimated de... more The mortality related to snake bites is an extreme public health problem because the estimated death prevalence per year is about 1,25,000 globally. Insufficient health services, bad transportation and consequent delay in synthetic anti-snake venom management are the main motives for excessive mortality. Adverse drug reactions and inadequate storage conditions limit the use of synthetic anti-snake venom. The medicinal flora, available domestically and used widely by traditional healers, consequently need attention. Most of the snake bite cases are typically undermined due to loss of proper consciousness of the mass people. However, present evaluation has been focused at the artificial and traditional herbs and their anti-venom property, which can be a venturing stone in setting up the future treatment against snake bite treatment and management.

Mushrooms have been consumed as food items and medications since earliest history; old Greeks had... more Mushrooms have been consumed as food items and medications since earliest history; old Greeks had a strong faith that mushrooms gave strength to warriors in fight and the Romans saw them as the "Food of the Gods". For hundreds of years, the Chinese culture has treasured mushrooms as a wellbeing nourishment, an "elixir of life." They have been a piece of the human culture for thousands of years and had been the item of considerable interest for the most essential civic establishments in history on account of their sensory attributes. Likewise, they additionally incorporate numerous bioactive metabolites which make mushrooms and truffles regular parts in medication, particularly in Africa, the Middle East, China and Japan. It is accounted for and in some cases have demonstrated that mushrooms have numerous pharmacological and remedial activity including anti-oxidant, anti-cancer, antiinflammatory, analgesic, nutraceutical and numerous others. However, this attempt ...

Future Journal of Pharmaceutical Sciences

Background The complementary and alternative medicines have particular importance in treating var... more Background The complementary and alternative medicines have particular importance in treating various comorbid conditions including anxiety and depression which prevalence will be raised to the second highest risk of morbidity, triggering a noteworthy socioeconomic burden. Ethanolic extract of leaves of Psidium guajava Linn (EEPG) was investigated to evaluate the anxiolytic and anti-depressant activity into two different doses (200 mg/kg and 400 mg/kg of body weight) on Swiss Albino male mice utilizing experimental paradigms of anxiety and depression. The extract was also subjected to phytochemical screening. Results Phytochemicals screening showed the presence of numerous types of active constituents in extract, for example, flavonoids, alkaloids, terpenoids, and steroids. The experimental results revealed that in case of anxiolytic activity tests, a statistical significant (p

Purpose: The purpose of the study was to outline the genomic and epidemiological characteristics ... more Purpose: The purpose of the study was to outline the genomic and epidemiological characteristics of COVID-19 in South Asian countries as well as the diagnosis, treatments, and prevention approaches undertaken by these countries to tackle the COVID-19 pandemic.Design/Methodology/Approach: We searched electronic databases such as Google Scholar, PubMed, and Scopus as well as various national and international COVID-19 websites, WHO databases, and electronic media. Total 63 articles were selected from databases and 34 articles from various other sources.Findings: Scientists observed genomic variations including common mutations in ORF1ab, ORF1a, ORF3a, and S genes, while several unique mutations exist in most isolates from these countries. Demographic analysis showed that the majority of the infected individuals were male and younger adults (20 to 40 years). India had both the highest number of deaths and incidents while Afghanistan had the highest fatality rate (4.37%). Various molecu...

Journal of Diabetes & Metabolic Disorders

The Egyptian Journal of Bronchology

An amendment to this paper has been published and can be accessed via the original article.

Future Journal of Pharmaceutical Sciences

Background Chenopodium album (Family: Amaranthaceae) is a nutritive herb mainly found in Banglade... more Background Chenopodium album (Family: Amaranthaceae) is a nutritive herb mainly found in Bangladesh and had reported that it is having different bioactive phytochemicals including polyphenols. It has a great popularity for it is traditionally used as a medicine against microorganisms, inflammation, and cancer. We designed this experiment to explore the in vivo anticancer effects of C. album leaf extract against Ehrlich ascites carcinoma (EAC) cells in Swiss albino mice. Results Administration of C. album leaf extract at concentration 200 (mg/kg) and 400 (mg/kg) showed 30.60% and 41.80% cell growth inhibition respectively that were statistically significant (***P < 0.001) and may lead to apoptosis, and the number of apoptotic cells were 37.5 ± 6.22, 54.67 ± 4.76 respectively (***P < 0.001). Plant extract at concentration 200 (mg/kg) and 400 (mg/kg) increased life span 22.27% and 51.07% respectively. Tumor weight decreased 18.50 ± 2.59 g, 13.67 ± 2.25 g respectively compared to ...

The Egyptian Journal of Bronchology

Background The ongoing acute respiratory disease pandemic termed COVID-19 caused by a newly emerg... more Background The ongoing acute respiratory disease pandemic termed COVID-19 caused by a newly emerged coronavirus has jeopardized the world’s health and economic sectors. As of 20 July 2020, the virus now known as SARS-CoV-2 has already infected more than 14 million individuals and killed 612,815 patients with a mortality rate of 4.12% around the world regardless of age, gender, and race. Main body Bangladesh has become one of its worst sufferers, with 207,453 infected people and 2668 related deaths with a mortality rate of 1.29% until 20 July 2020. More than 50% of COVID-19 patients in Bangladesh are aged between 21 and 40, but elderly people aged more than 60 have the highest mortality rate (44.7%). Male individuals are also more susceptible to the virus than females and consist of 71% and 79% among the infected and deceased patients, respectively. The most prevalent clinical features following the virus incubation period are fever, fatigue, and dry cough. A phylogenetic analysis st...

Mushrooms have been consumed as food items and medications since earliest history; old Greeks had... more Mushrooms have been consumed as food items and medications since earliest history; old Greeks had a strong faith that mushrooms gave strength to warriors in fight and the Romans saw them as the "Food of the Gods". For hundreds of years, the Chinese culture has treasured mushrooms as a wellbeing nourishment, an "elixir of life." They have been a piece of the human culture for thousands of years and had been the item of considerable interest for the most essential civic establishments in history on account of their sensory attributes. Likewise, they additionally incorporate numerous bioactive metabolites which make mushrooms and truffles regular parts in medication, particularly in Africa, the Middle East, China and Japan. It is accounted for and in some cases have demonstrated that mushrooms have numerous pharmacological and remedial activity including anti-oxidant, anti-cancer, anti-inflammatory, analgesic, nutraceutical and numerous others. However, this attempt has been made to concentrate on the short reviews of anti-oxidant, anti-inflammatory, analgesic and food values of mostly used mushrooms all over the world.

Background/Objectives: Cardiovascular disease (CVD) is the most concerning disease in health sect... more Background/Objectives: Cardiovascular disease (CVD) is the most concerning disease in health sectors, whole over the world. Some environmental parameters and physical condition affect on the cardiac health. We therefore observed a cross sectional study of cardiac health condition and analysis to effect risks factors study. Methods: This cross sectional study was performed on hypertensive patients with their treatment managements. Study area, study population & sample and data collection were well performed by informative questionnaires. Significance of variants data was analyzed considering p<0.05 by SPSS software. Results: This estimated hypertensive patient's data was 25.4% female and 74.6% male. 36 to 50 years holdings patients was to be highest, containing 43.8% and their systolic pressure (Mean ±SD) was 143.15±10.51. Age depending Odds Ratio [confidence interval] for 60 up age patients was 1.996[0.756-5.269]. Consideration of BMI index the Odds Ratio (confidence interval) of obese patients was 6.258(2.595-15.088). Most choice of treatment managements of hypertensive patients was angiotensine receptor blockers. With hypertension some cardiovascular complication were to be occurred , in these condition some combination drugs were to be referred, most choice of drugs was angiotensine receptor blockers and diuretics combination preparation. Conclusion: Population based cross sectional study in Jessore region was to be estimated cardiovascular diseases and screen out informative knowledge of hypertensive risk factors.

The Pharma Innovation Journal, 2017

International Journal of Biomedical and Advance Research, 2017

Journal of Pharmaceutical Research International, 2018

International Journal of Food Science and Biotechnology, 2019

Future Journal of Pharmaceutical Sciences

Journal of Diabetes & Metabolic Disorders

The Egyptian Journal of Bronchology

An amendment to this paper has been published and can be accessed via the original article.

Future Journal of Pharmaceutical Sciences

The Egyptian Journal of Bronchology

Mushrooms have been consumed as food items and medications since earliest history; old Greeks had... more Mushrooms have been consumed as food items and medications since earliest history; old Greeks had a strong faith that mushrooms gave strength to warriors in fight and the Romans saw them as the "Food of the Gods". For hundreds of years, the Chinese culture has treasured mushrooms as a wellbeing nourishment, an "elixir of life." They have been a piece of the human culture for thousands of years and had been the item of considerable interest for the most essential civic establishments in history on account of their sensory attributes. Likewise, they additionally incorporate numerous bioactive metabolites which make mushrooms and truffles regular parts in medication, particularly in Africa, the Middle East, China and Japan. It is accounted for and in some cases have demonstrated that mushrooms have numerous pharmacological and remedial activity including anti-oxidant, anti-cancer, anti-inflammatory, analgesic, nutraceutical and numerous others. However, this attempt has been made to concentrate on the short reviews of anti-oxidant, anti-inflammatory, analgesic and food values of mostly used mushrooms all over the world.