Bilal Ahmad Rahimi | Kandahar university (original) (raw)

Papers by Bilal Ahmad Rahimi

Research paper thumbnail of Analysis of the output of "Razi International Medical Journal" during 2021-2023 and future directions

Razi international medical journal, May 30, 2024

Research paper thumbnail of Prevalence and associated risk factors of stunting, wasting/thinness, and underweight among primary school children in Kandahar city, Afghanistan: a cross-sectional analytical study

Research paper thumbnail of Bioequivalence of a new coated 15 mg primaquine formulation for malaria elimination

Malaria journal, Jun 5, 2024

Research paper thumbnail of Afghanistan National Depression Screening (ANDs) scale: development and psychometric testing

Discover Psychology, May 18, 2024

Research paper thumbnail of Health survey on anxiety, depression, and stress in Afghanistan: A large-scale cross-sectional survey study

Research paper thumbnail of Mortality in Surgical Site Infections Post-cardiac Surgery - a Prospective, International Id-iri Study

Research Square (Research Square), Apr 29, 2024

Research paper thumbnail of Anxiety symptoms and sleep disturbance among Afghan female school students: A survey study

Research Square (Research Square), Mar 27, 2024

Research paper thumbnail of Understanding clinical outcomes and factors influencing mortality in intensive care unit patients with COVID‐19‐associated candidemia

Mycoses, Dec 31, 2023

Background: During the COVID pandemic, research has shown an increase in candidemia cases followi... more Background: During the COVID pandemic, research has shown an increase in candidemia cases following severe COVID infection and the identification of risk factors associated with candidemia. However, there is a lack of studies that specifically explore clinical outcomes and mortality rates related to candidemia after COVID infection. Objectives: The aim of this international study was to evaluate the clinical outcomes and identify factors influencing mortality in patients who developed candidemia during their COVID infection. Patients/Methods: This study included adult patients (18 years of age or older) admitted to the intensive care unit (ICU) and diagnosed with COVID-associated candidemia (CAC). The research was conducted through ID-IRI network and in collaboration with 34 medical centres across 18 countries retrospectively, spanning from the beginning of the COVID pandemic until December 2021. Results: A total of 293 patients diagnosed with CAC were included. The median age of the patients was 67, and 63% of them were male. The most common Candida species detected was C. albicans. The crude 30-day mortality rate was recorded at 62.4%. The This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Research paper thumbnail of Antibiotic Resistance among Patients with Urinary Tract Infections in Kandahar, Afghanistan

Indian Journal of Community Medicine, Dec 31, 2022

IntroductIon Antimicrobial resistance is a global public health threat. [1] Highest burden of res... more IntroductIon Antimicrobial resistance is a global public health threat. [1] Highest burden of resistance is reported from low-and middle-income countries due to several factors, including lack of surveillance capacity and systematic data collection of antimicrobial resistance. [2,3] Currently, UTI represents one of the most common diseases encountered in clinical practice, affecting people of all age groups, from neonatal to geriatric age groups. [4] The most commonly reported bacterial cause of UTI is Escherichia coli, followed by others such as Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa. [5,6] UTI due to multidrug resistance (MDR) bacteria treated with inappropriate empirical antibiotics is related to serious complications (like sepsis and increased mortality), increased treatment cost and hospital stay, and loss of working days. [7,8] Antibiotic resistance mostly differs by geographical location. [9] Therefore, local susceptibility studies are crucial to determine the most effective antibiotics to improve empirical prescription and minimize the treatment cost and duration. [10] Unfortunately, we could not find any published research from Kandahar and even whole Afghanistan that investigates the antibiotic resistance against uropathogens in UTI patients. Background: Antimicrobial resistance is a global public health threat. Highest burden of resistance is reported from low-and middle-income countries. Objectives: To investigate and report the current scenario of increased antibiotic resistance of uropathogens among symptomatic urinary tract infection patients in Kandahar, Afghanistan. Methods: From January 2018 to December 2021, this retrospective study was carried out at two main hospitals in Kandahar City, Afghanistan. Here, culture and sensitivity profiles of uropathogens were studied among symptomatic Bacteriuria in the presence of genitourinary symptoms (i.e., dysuria, suprapubic pain or tenderness, frequency, or urgency) (UTI) patients. Results: Among urine samples of 1589 patients, 1047 (65.9%) were culture positive and included in this study. Most of these patients (626/1047 [59.8%]) were females, with majority (818 [78.1%]) having age between 19 and 39 years. Gram-negative bacteria were the most prevalent (840/1047 [80.2%]), with E. coli (653/1047 [62.4%]) as the most common isolated uropathogen. Overall gram-negative bacteria had higher resistance against commonly used antibiotics of cotrimoxazole (62.8%), ciprofloxacin (56.0%), levofloxacin (47.5%), cefixime (44.5%), fosfomycin (41.5%), and even ceftriaxone (48.3%). Conclusions: Kandahar province has higher resistance rates against commonly used empirical antibiotics like norfloxacin, ciprofloxacin, levofloxacin, and cefixime. Nitrofurantoin should be used as the first-line antibiotic in treating UTI patients. Public health authorities should make strict regulations and policies to reduce irrational use, inappropriate prescription, and over-the-counter availability of antibiotics in Kandahar.

Research paper thumbnail of Infectious causes of fever of unknown origin in developing countries: An international ID-IRI study

Journal of Intensive Medicine, Aug 31, 2023

Research paper thumbnail of Predictors of non-adherence to antihypertensive medications: A cross-sectional study from a regional hospital in Afghanistan

Research paper thumbnail of Determinants of Exclusive Breastfeeding Practices in Kandahar, Afghanistan: A Cross-Sectional Analytical Study

International Journal of Pediatrics, Apr 1, 2020

Background It is recommended for mothers to start breastfeeding their infants within the first ho... more Background It is recommended for mothers to start breastfeeding their infants within the first hour after birth and exclusively breastfeed them for the first 6 months of their life. Exclusive breastfeeding (EBF) has both short-and long-term benefits for both mother and infant. Main objective of this study was to establish the determinants of EBF practices among mothers in Kandahar, Afghanistan. Materials and Methods This was a cross-sectional analytical study conducted in Kandahar, Afghanistan. Researcher-made questionnaire was used to collect the data from 1,028 mothers with children <2 years of age who visited either of the seven health clinics of the city during a period of 6 months (June-November, 2018). Data was analysed using SPSS software version 22.0 Results Among 1,028 mothers, 95.9% were uneducated, 53.9% had low socioeconomic status, and 94.2% had antenatal care (ANC) visits. EBF rate was 51.2% (526/1028). During first 6 months of life, 11.1% of the infants were given foods other than milk while 51.4% used pacifier. Weaning was started in nearly half (49.2%) of the infants before 6 months of age. Main barriers to EBF were living in city, male gender, giving sedative syrup (Promethazine) to infant, breastfeeding the infant ≥8 times in 24 hours, and giving expressed milk. Conclusion EBF rate in Kandahar is better than many parts of the world, but there are still many barriers that need to be removed. Main barriers of EBF rate in Kandahar needs to be decreased by increasing the health education and overall education status of the mothers.

Research paper thumbnail of Conducting Health Research in the Current Afghan Society: Challenges, Opportunities, and Recommendations

Risk Management and Healthcare Policy

Research makes a significant contribution to academic excellence and holds the potential to facil... more Research makes a significant contribution to academic excellence and holds the potential to facilitate societal development. Despite the increasing importance of health research in developing new therapies and galvanizing notable progress in public health, the landscape of health research in Afghanistan remains profoundly deficient. This article reveals that health research in Afghanistan requires significant growth to meet the standards set on regional and global grounds.

Research paper thumbnail of Prevalence of soil-transmitted helminths and associated risk factors among primary school children in Kandahar, Afghanistan: A cross-sectional analytical study

PLOS Neglected Tropical Diseases, 2023

Background Soil-transmitted helminth (STH) infections are global health problem, especially in lo... more Background Soil-transmitted helminth (STH) infections are global health problem, especially in low-income countries. Main objectives of this study were to estimate the prevalence and intensity of STH and its risk factors among school children in Kandahar city of Afghanistan. Methodology/principal findings This was a school-based cross-sectional analytical study, with data collected during eight-month-period (May–December, 2022) from 6- and 12-years old school children in Kandahar city, Afghanistan. All the stool samples were examined by saline wet mount method and Kato–Katz technique. Data were analyzed by using descriptive statistics, Chi square test, and multivariate logistic regression. A total of 1275 children from eight schools of Kandahar city were included in this study. Mean age of these children was 8.3 years with 53.3% boys. The overall prevalence of any intestinal parasitic infection was 68.4%. The overall prevalence of STH infection was 39.1%, with Ascaris lumbricoides (...

Research paper thumbnail of Knowledge, attitudes and practices of university students toward COVID-19 in Southern region, Afghanistan: a cross-sectional study

BMC Medical Education

Background Successful implementation of preventive measures and level of awareness in particular ... more Background Successful implementation of preventive measures and level of awareness in particular among university students in Afghanistan could play a crucial role in spreading the information for better control of the ongoing pandemic. Therefore, the aim of this study was to determine the level of knowledge, attitudes and practices (KAP) regarding COVID-19 among Kandahar university students. Methods A cross-sectional study conducted among undergraduate students to investigate their KAP regarding COVID-19 from January to March, 2021. The data were collected using a structured questionnaire (socio-demographic characteristics, KAP questionnaire) by phone call interviews. Results From 359 participants, 88.9% were males, 81.3% were single, 65.1% lived in urban areas, and more than 64% of the students were less than 23 years old. Overall, 86.6% of the study participants had adequate level of knowledge and 87.5% had positive attitudes toward COVID-19. Almost one-third of the participants ...

Research paper thumbnail of Post-traumatic stress disorder (PTSD) probability among parents who live in Kandahar, Afghanistan and lost at least a child to armed conflict

Scientific Reports

The last 4 decades of conflict in Afghanistan resulted in incalculable deaths, injuries, and mill... more The last 4 decades of conflict in Afghanistan resulted in incalculable deaths, injuries, and millions of displacements. Although there are routine reports on casualties of the warfare, the information on its long-term psycho-social sequelae is somehow discounted. This study aimed to assess post-traumatic stress disorder (PTSD) probability and its associated factors among parents who live in Kandahar, the southern province of Afghanistan, and lost at least one child to armed conflict. We conducted a health-facility-based cross-sectional study involving 474 bereaved parents in Kandahar province from November/2020 to January/2021. The questionnaire was composed of sections on socio-demographic characteristics and mental and medical histories of the parent, features of the traumatic event and the time elapsed since then, age and gender of the lost child, and PCL-5. We performed multivariable logistic analysis to determine factors associated with PTSD probability in such parents. A stagg...

Research paper thumbnail of Classical fever of unknown origin in 21 countries with different economic development: an international ID-IRI study

European Journal of Clinical Microbiology & Infectious Diseases

Fever of unknown origin (FUO) is a serious challenge for physicians. The aim of the present study... more Fever of unknown origin (FUO) is a serious challenge for physicians. The aim of the present study was to consider epidemiology and dynamics of FUO in countries with different economic development. The data of FUO patients hospitalized/ followed between 1st July 2016 and 1st July 2021 were collected retrospectively and submitted from referral centers in 21 countries through ID-IRI clinical research platform. The countries were categorized into developing (low-income (LI) and lower middle-income (LMI) economies) and developed countries (upper middle-income (UMI) and high-income (HI) economies). This research included 788 patients. FUO diagnoses were as follows: infections (51.6%; n = 407), neoplasms (11.4%, n = 90), collagen vascular disorders (9.3%, n = 73), undiagnosed (20.1%, n = 158), miscellaneous diseases (7.7%, n = 60). The most common infections were tuberculosis (n = 45, 5.7%), brucellosis (n = 39, 4.9%), rickettsiosis (n = 23, 2.9%), HIV infection (n = 20, 2.5%), and typhoid fever (n = 13, 1.6%). Cardiovascular infections (n = 56, 7.1%) were the most common infectious syndromes. Only collagen vascular disorders were reported significantly more from developed countries (RR = 2.00, 95% CI: 1.19-3.38). FUO had similar characteristics in LI/LMI and UMI/HI countries including the portion of undiagnosed cases (OR, 95% CI; 0.87 (0.65-1.15)), death attributed to FUO (RR = 0.87, 95% CI: 0.65-1.15, p-value = 0.3355), and the mean duration until diagnosis (p = 0.9663). Various aspects of FUO cannot be determined by the economic development solely. Other development indices can be considered in future analyses. Physicians in different countries should be equally prepared for FUO patients.

Research paper thumbnail of Challenges in antenatal care utilization in Kandahar, Afghanistan: A cross-sectional analytical study

PLOS ONE

Background Quality antenatal care (ANC) is one of the four pillars of safe motherhood initiatives... more Background Quality antenatal care (ANC) is one of the four pillars of safe motherhood initiatives and improves the survival and health of mother and neonate. The main objective of this study was to assess the barriers in the utilization of ANC services in Kandahar, Afghanistan. Methods This was a cross-sectional analytical study conducted over one year from December 2018–November 2019. Data were analyzed by descriptive statistics, Chi squared, and binary logistic regression. Results A total of 1524 women were recruited in this study with mean age of 30.3 years. Of these women, 848 (55.6%) were rural dwellers, 1450/1510 (96.0%) were illiterate, 438/608 (72.0%) belonged to low-income families, 1112/1508 (73.7%) lived in joint families, 1420/1484 (95.7%) lived in a house of >10 inhabitants, while 388/1494 (26.0%) had attended had at least one ANC visit during their last pregnancy. On univariate analysis, the main barriers in the utilization of ANC services were living in rural areas...

Research paper thumbnail of Treatment outcomes and risk factors of death in childhood tuberculous meningitis in Kandahar, Afghanistan: a prospective observational cohort study

Transactions of The Royal Society of Tropical Medicine and Hygiene

Background Tuberculous meningitis (TBM) is the most severe form of TB. We prospectively documente... more Background Tuberculous meningitis (TBM) is the most severe form of TB. We prospectively documented the treatment outcomes and the risk factors for death in children with TBM from Kandahar, Afghanistan. Methods This prospective observational cohort study was conducted from February 2017 to January 2020 in hospitalised TBM children. All the patients were prospectively followed up for 12 mo. Data were analysed by using descriptive statistics, χ2 and multivariate logistic regression. Results A total of 818 TBM hospitalised patients with median age 4.8 (0.8–14.5) y were recruited. Females accounted for 60.9% (498/818). Upon admission 53.9% (n=441) and 15.2% (n=124) had TBM stages II and III, respectively, and 23.2% (n=190) had focal neurological signs. The case fatality rate was 20.2% (160/794) and 30.6% (243/794) survived with neurological sequelae. Independent risk factors for death were being unvaccinated for BCG (adjusted OR [AOR] 3.8, 95% CI 1.8 to 8.1), not receiving dexamethasone ...

Research paper thumbnail of Correction to: Prevalence and associated risk factors of soil-transmitted helminth infections in Kandahar, Afghanistan

Research paper thumbnail of Analysis of the output of "Razi International Medical Journal" during 2021-2023 and future directions

Razi international medical journal, May 30, 2024

Research paper thumbnail of Prevalence and associated risk factors of stunting, wasting/thinness, and underweight among primary school children in Kandahar city, Afghanistan: a cross-sectional analytical study

Research paper thumbnail of Bioequivalence of a new coated 15 mg primaquine formulation for malaria elimination

Malaria journal, Jun 5, 2024

Research paper thumbnail of Afghanistan National Depression Screening (ANDs) scale: development and psychometric testing

Discover Psychology, May 18, 2024

Research paper thumbnail of Health survey on anxiety, depression, and stress in Afghanistan: A large-scale cross-sectional survey study

Research paper thumbnail of Mortality in Surgical Site Infections Post-cardiac Surgery - a Prospective, International Id-iri Study

Research Square (Research Square), Apr 29, 2024

Research paper thumbnail of Anxiety symptoms and sleep disturbance among Afghan female school students: A survey study

Research Square (Research Square), Mar 27, 2024

Research paper thumbnail of Understanding clinical outcomes and factors influencing mortality in intensive care unit patients with COVID‐19‐associated candidemia

Mycoses, Dec 31, 2023

Background: During the COVID pandemic, research has shown an increase in candidemia cases followi... more Background: During the COVID pandemic, research has shown an increase in candidemia cases following severe COVID infection and the identification of risk factors associated with candidemia. However, there is a lack of studies that specifically explore clinical outcomes and mortality rates related to candidemia after COVID infection. Objectives: The aim of this international study was to evaluate the clinical outcomes and identify factors influencing mortality in patients who developed candidemia during their COVID infection. Patients/Methods: This study included adult patients (18 years of age or older) admitted to the intensive care unit (ICU) and diagnosed with COVID-associated candidemia (CAC). The research was conducted through ID-IRI network and in collaboration with 34 medical centres across 18 countries retrospectively, spanning from the beginning of the COVID pandemic until December 2021. Results: A total of 293 patients diagnosed with CAC were included. The median age of the patients was 67, and 63% of them were male. The most common Candida species detected was C. albicans. The crude 30-day mortality rate was recorded at 62.4%. The This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Research paper thumbnail of Antibiotic Resistance among Patients with Urinary Tract Infections in Kandahar, Afghanistan

Indian Journal of Community Medicine, Dec 31, 2022

IntroductIon Antimicrobial resistance is a global public health threat. [1] Highest burden of res... more IntroductIon Antimicrobial resistance is a global public health threat. [1] Highest burden of resistance is reported from low-and middle-income countries due to several factors, including lack of surveillance capacity and systematic data collection of antimicrobial resistance. [2,3] Currently, UTI represents one of the most common diseases encountered in clinical practice, affecting people of all age groups, from neonatal to geriatric age groups. [4] The most commonly reported bacterial cause of UTI is Escherichia coli, followed by others such as Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa. [5,6] UTI due to multidrug resistance (MDR) bacteria treated with inappropriate empirical antibiotics is related to serious complications (like sepsis and increased mortality), increased treatment cost and hospital stay, and loss of working days. [7,8] Antibiotic resistance mostly differs by geographical location. [9] Therefore, local susceptibility studies are crucial to determine the most effective antibiotics to improve empirical prescription and minimize the treatment cost and duration. [10] Unfortunately, we could not find any published research from Kandahar and even whole Afghanistan that investigates the antibiotic resistance against uropathogens in UTI patients. Background: Antimicrobial resistance is a global public health threat. Highest burden of resistance is reported from low-and middle-income countries. Objectives: To investigate and report the current scenario of increased antibiotic resistance of uropathogens among symptomatic urinary tract infection patients in Kandahar, Afghanistan. Methods: From January 2018 to December 2021, this retrospective study was carried out at two main hospitals in Kandahar City, Afghanistan. Here, culture and sensitivity profiles of uropathogens were studied among symptomatic Bacteriuria in the presence of genitourinary symptoms (i.e., dysuria, suprapubic pain or tenderness, frequency, or urgency) (UTI) patients. Results: Among urine samples of 1589 patients, 1047 (65.9%) were culture positive and included in this study. Most of these patients (626/1047 [59.8%]) were females, with majority (818 [78.1%]) having age between 19 and 39 years. Gram-negative bacteria were the most prevalent (840/1047 [80.2%]), with E. coli (653/1047 [62.4%]) as the most common isolated uropathogen. Overall gram-negative bacteria had higher resistance against commonly used antibiotics of cotrimoxazole (62.8%), ciprofloxacin (56.0%), levofloxacin (47.5%), cefixime (44.5%), fosfomycin (41.5%), and even ceftriaxone (48.3%). Conclusions: Kandahar province has higher resistance rates against commonly used empirical antibiotics like norfloxacin, ciprofloxacin, levofloxacin, and cefixime. Nitrofurantoin should be used as the first-line antibiotic in treating UTI patients. Public health authorities should make strict regulations and policies to reduce irrational use, inappropriate prescription, and over-the-counter availability of antibiotics in Kandahar.

Research paper thumbnail of Infectious causes of fever of unknown origin in developing countries: An international ID-IRI study

Journal of Intensive Medicine, Aug 31, 2023

Research paper thumbnail of Predictors of non-adherence to antihypertensive medications: A cross-sectional study from a regional hospital in Afghanistan

Research paper thumbnail of Determinants of Exclusive Breastfeeding Practices in Kandahar, Afghanistan: A Cross-Sectional Analytical Study

International Journal of Pediatrics, Apr 1, 2020

Background It is recommended for mothers to start breastfeeding their infants within the first ho... more Background It is recommended for mothers to start breastfeeding their infants within the first hour after birth and exclusively breastfeed them for the first 6 months of their life. Exclusive breastfeeding (EBF) has both short-and long-term benefits for both mother and infant. Main objective of this study was to establish the determinants of EBF practices among mothers in Kandahar, Afghanistan. Materials and Methods This was a cross-sectional analytical study conducted in Kandahar, Afghanistan. Researcher-made questionnaire was used to collect the data from 1,028 mothers with children <2 years of age who visited either of the seven health clinics of the city during a period of 6 months (June-November, 2018). Data was analysed using SPSS software version 22.0 Results Among 1,028 mothers, 95.9% were uneducated, 53.9% had low socioeconomic status, and 94.2% had antenatal care (ANC) visits. EBF rate was 51.2% (526/1028). During first 6 months of life, 11.1% of the infants were given foods other than milk while 51.4% used pacifier. Weaning was started in nearly half (49.2%) of the infants before 6 months of age. Main barriers to EBF were living in city, male gender, giving sedative syrup (Promethazine) to infant, breastfeeding the infant ≥8 times in 24 hours, and giving expressed milk. Conclusion EBF rate in Kandahar is better than many parts of the world, but there are still many barriers that need to be removed. Main barriers of EBF rate in Kandahar needs to be decreased by increasing the health education and overall education status of the mothers.

Research paper thumbnail of Conducting Health Research in the Current Afghan Society: Challenges, Opportunities, and Recommendations

Risk Management and Healthcare Policy

Research makes a significant contribution to academic excellence and holds the potential to facil... more Research makes a significant contribution to academic excellence and holds the potential to facilitate societal development. Despite the increasing importance of health research in developing new therapies and galvanizing notable progress in public health, the landscape of health research in Afghanistan remains profoundly deficient. This article reveals that health research in Afghanistan requires significant growth to meet the standards set on regional and global grounds.

Research paper thumbnail of Prevalence of soil-transmitted helminths and associated risk factors among primary school children in Kandahar, Afghanistan: A cross-sectional analytical study

PLOS Neglected Tropical Diseases, 2023

Background Soil-transmitted helminth (STH) infections are global health problem, especially in lo... more Background Soil-transmitted helminth (STH) infections are global health problem, especially in low-income countries. Main objectives of this study were to estimate the prevalence and intensity of STH and its risk factors among school children in Kandahar city of Afghanistan. Methodology/principal findings This was a school-based cross-sectional analytical study, with data collected during eight-month-period (May–December, 2022) from 6- and 12-years old school children in Kandahar city, Afghanistan. All the stool samples were examined by saline wet mount method and Kato–Katz technique. Data were analyzed by using descriptive statistics, Chi square test, and multivariate logistic regression. A total of 1275 children from eight schools of Kandahar city were included in this study. Mean age of these children was 8.3 years with 53.3% boys. The overall prevalence of any intestinal parasitic infection was 68.4%. The overall prevalence of STH infection was 39.1%, with Ascaris lumbricoides (...

Research paper thumbnail of Knowledge, attitudes and practices of university students toward COVID-19 in Southern region, Afghanistan: a cross-sectional study

BMC Medical Education

Background Successful implementation of preventive measures and level of awareness in particular ... more Background Successful implementation of preventive measures and level of awareness in particular among university students in Afghanistan could play a crucial role in spreading the information for better control of the ongoing pandemic. Therefore, the aim of this study was to determine the level of knowledge, attitudes and practices (KAP) regarding COVID-19 among Kandahar university students. Methods A cross-sectional study conducted among undergraduate students to investigate their KAP regarding COVID-19 from January to March, 2021. The data were collected using a structured questionnaire (socio-demographic characteristics, KAP questionnaire) by phone call interviews. Results From 359 participants, 88.9% were males, 81.3% were single, 65.1% lived in urban areas, and more than 64% of the students were less than 23 years old. Overall, 86.6% of the study participants had adequate level of knowledge and 87.5% had positive attitudes toward COVID-19. Almost one-third of the participants ...

Research paper thumbnail of Post-traumatic stress disorder (PTSD) probability among parents who live in Kandahar, Afghanistan and lost at least a child to armed conflict

Scientific Reports

The last 4 decades of conflict in Afghanistan resulted in incalculable deaths, injuries, and mill... more The last 4 decades of conflict in Afghanistan resulted in incalculable deaths, injuries, and millions of displacements. Although there are routine reports on casualties of the warfare, the information on its long-term psycho-social sequelae is somehow discounted. This study aimed to assess post-traumatic stress disorder (PTSD) probability and its associated factors among parents who live in Kandahar, the southern province of Afghanistan, and lost at least one child to armed conflict. We conducted a health-facility-based cross-sectional study involving 474 bereaved parents in Kandahar province from November/2020 to January/2021. The questionnaire was composed of sections on socio-demographic characteristics and mental and medical histories of the parent, features of the traumatic event and the time elapsed since then, age and gender of the lost child, and PCL-5. We performed multivariable logistic analysis to determine factors associated with PTSD probability in such parents. A stagg...

Research paper thumbnail of Classical fever of unknown origin in 21 countries with different economic development: an international ID-IRI study

European Journal of Clinical Microbiology & Infectious Diseases

Fever of unknown origin (FUO) is a serious challenge for physicians. The aim of the present study... more Fever of unknown origin (FUO) is a serious challenge for physicians. The aim of the present study was to consider epidemiology and dynamics of FUO in countries with different economic development. The data of FUO patients hospitalized/ followed between 1st July 2016 and 1st July 2021 were collected retrospectively and submitted from referral centers in 21 countries through ID-IRI clinical research platform. The countries were categorized into developing (low-income (LI) and lower middle-income (LMI) economies) and developed countries (upper middle-income (UMI) and high-income (HI) economies). This research included 788 patients. FUO diagnoses were as follows: infections (51.6%; n = 407), neoplasms (11.4%, n = 90), collagen vascular disorders (9.3%, n = 73), undiagnosed (20.1%, n = 158), miscellaneous diseases (7.7%, n = 60). The most common infections were tuberculosis (n = 45, 5.7%), brucellosis (n = 39, 4.9%), rickettsiosis (n = 23, 2.9%), HIV infection (n = 20, 2.5%), and typhoid fever (n = 13, 1.6%). Cardiovascular infections (n = 56, 7.1%) were the most common infectious syndromes. Only collagen vascular disorders were reported significantly more from developed countries (RR = 2.00, 95% CI: 1.19-3.38). FUO had similar characteristics in LI/LMI and UMI/HI countries including the portion of undiagnosed cases (OR, 95% CI; 0.87 (0.65-1.15)), death attributed to FUO (RR = 0.87, 95% CI: 0.65-1.15, p-value = 0.3355), and the mean duration until diagnosis (p = 0.9663). Various aspects of FUO cannot be determined by the economic development solely. Other development indices can be considered in future analyses. Physicians in different countries should be equally prepared for FUO patients.

Research paper thumbnail of Challenges in antenatal care utilization in Kandahar, Afghanistan: A cross-sectional analytical study

PLOS ONE

Background Quality antenatal care (ANC) is one of the four pillars of safe motherhood initiatives... more Background Quality antenatal care (ANC) is one of the four pillars of safe motherhood initiatives and improves the survival and health of mother and neonate. The main objective of this study was to assess the barriers in the utilization of ANC services in Kandahar, Afghanistan. Methods This was a cross-sectional analytical study conducted over one year from December 2018–November 2019. Data were analyzed by descriptive statistics, Chi squared, and binary logistic regression. Results A total of 1524 women were recruited in this study with mean age of 30.3 years. Of these women, 848 (55.6%) were rural dwellers, 1450/1510 (96.0%) were illiterate, 438/608 (72.0%) belonged to low-income families, 1112/1508 (73.7%) lived in joint families, 1420/1484 (95.7%) lived in a house of >10 inhabitants, while 388/1494 (26.0%) had attended had at least one ANC visit during their last pregnancy. On univariate analysis, the main barriers in the utilization of ANC services were living in rural areas...

Research paper thumbnail of Treatment outcomes and risk factors of death in childhood tuberculous meningitis in Kandahar, Afghanistan: a prospective observational cohort study

Transactions of The Royal Society of Tropical Medicine and Hygiene

Background Tuberculous meningitis (TBM) is the most severe form of TB. We prospectively documente... more Background Tuberculous meningitis (TBM) is the most severe form of TB. We prospectively documented the treatment outcomes and the risk factors for death in children with TBM from Kandahar, Afghanistan. Methods This prospective observational cohort study was conducted from February 2017 to January 2020 in hospitalised TBM children. All the patients were prospectively followed up for 12 mo. Data were analysed by using descriptive statistics, χ2 and multivariate logistic regression. Results A total of 818 TBM hospitalised patients with median age 4.8 (0.8–14.5) y were recruited. Females accounted for 60.9% (498/818). Upon admission 53.9% (n=441) and 15.2% (n=124) had TBM stages II and III, respectively, and 23.2% (n=190) had focal neurological signs. The case fatality rate was 20.2% (160/794) and 30.6% (243/794) survived with neurological sequelae. Independent risk factors for death were being unvaccinated for BCG (adjusted OR [AOR] 3.8, 95% CI 1.8 to 8.1), not receiving dexamethasone ...

Research paper thumbnail of Correction to: Prevalence and associated risk factors of soil-transmitted helminth infections in Kandahar, Afghanistan