EBRU GUZEL | Karabuk University (original) (raw)

Papers by EBRU GUZEL

Research paper thumbnail of Analysis of MR Imaging of Wrists in Female Patients with Carpal Tunnel Syndrome and Healthy Controls

International Journal of Morphology, 2009

Research paper thumbnail of Endoplasmic reticulum (ER) homeostasis is cycle-dependent and the inflammatory cytokines TNF-α and ILI1β induce er stress by regulating BIP expression in human endometrial ENDOTHELIAL CELLS

Fertility and Sterility, 2011

Research paper thumbnail of Bidirectional regulation of unfolding protein response in human endometrium and endometriosis

Fertility and Sterility, 2010

hours, the cell number was measured with calcein uptake assay and analyzed via a fluorescent plat... more hours, the cell number was measured with calcein uptake assay and analyzed via a fluorescent plate reader at 485/583 nm. Mean values for each treatment (n¼3-8 experiments) were compared with ANOVA test.

Research paper thumbnail of Atypical Clinical Presentation of Idiophatic Thoracic Spinal Cord Herniation

Spine, 2008

Study Design. Case report. Objective. To report an adult female patient with idiopathic spinal co... more Study Design. Case report. Objective. To report an adult female patient with idiopathic spinal cord herniation presenting with pain without symptoms of myelopathy.

Research paper thumbnail of Cervical Spinal Meningioma Mimicking Intramedullary Spinal Tumor

Spine, 2009

Objective. To report a very unusual spinal meningioma, mimicking an intramedullary spinal tumor.

Research paper thumbnail of Pituitary Carcinoma Presenting with Multiple Metastases: Case Report

Journal of Child Neurology, 2008

1 that time had revealed communicating hydrocephalus without evidence of a sellar tumor (Figure 1... more 1 that time had revealed communicating hydrocephalus without evidence of a sellar tumor (Figure 1). However, cranial magnetic resonance (MR) imaging performed on admission did not show shunt dysfunction. P ituitary carcinoma, a rare central nervous system (CNS) tumor seen in adults, represents only about 0.1% to 0.2% of all pituitary tumors. 1-4 Pituitary carcinomas generally present with distant cerebrospinal and/or systemic metastases rather than local invasion. 4 All the cases of pituitary carcinomas in the literature (in English) involve adults. 1,4-7 To our knowledge, ours is the first case of pituitary carcinoma in a pediatric patient.

Research paper thumbnail of Serum neuron-specific enolase as a predictor of short-term outcome and its correlation with Glasgow Coma Scale in traumatic brain injury

Neurosurgical Review, 2008

Elevated serum neuron-specific enolase levels are correlated with brain cell damage. Low scores a... more Elevated serum neuron-specific enolase levels are correlated with brain cell damage. Low scores according to Glasgow Coma Scale are also considered as serious poor prognostic factor. The aims of the study were to investigate whether there is a correlation between the two measurements in patients with traumatic brain injury and whether serum neuron-specific enolase levels have potential as a screening test to predict outcome. A total of 169 consecutive patients with traumatic brain injury admitted to our clinic between 2002 and 2005 are included in this study. Those patients, who had any major health problem before trauma, were excluded from the study. However, patients with isolated head injury were included in the study. Serial serum neuron-specific enolase concentrations taken at the first 2, 24, and 48 h after traumatic brain injury were analyzed. A computed tomography was performed on each patient on admission. Their Glasgow Coma Scale scores were recorded serially. The relationship between Glasgow Coma Scale scores and the serum neuron-specific enolase levels were assessed by statistical methods. There was a significant negative correlation between the serum neuron-specific enolase levels and Glasgow Coma Scale scores. The levels of neuron-specific enolase were significantly higher in the patients who died in 30 days after trauma and whose scores were lower than or equal to 8 points in Glasgow Coma Scale. Although there are several serious limitations of the use of neuron-specific enolase as a biomarker in traumatic brain injury (i.e., hypoperfusion, extracranial trauma, bleeding, liver, or kidney damage also increase the level of neuron-specific enolase), its concentrations may be useful as a practical and helpful screening test to identify neurotrauma patients who are at increased risk and may provide supplementary estimation with radiological and clinical findings.

Research paper thumbnail of CT and MR imaging of chronic subdural haematomas: a comparative study

Questions under study/principles: This study was designed to compare CT and MR appearances of chr... more Questions under study/principles: This study was designed to compare CT and MR appearances of chronic subdural haematomas as well as CT-and MR-guided measurements of haematoma thicknesses.

Research paper thumbnail of Complete L1-L2 Lateral Dislocation without Fracture and Neurologic Deficit in a Child

Pediatric Neurosurgery, 2006

other organs . Sixty percent of pediatric spinal traumas are seen in the cervical region, frequen... more other organs . Sixty percent of pediatric spinal traumas are seen in the cervical region, frequently resulting in fracture-type injury, and in particular, after the age of 8. Dislocation without fracture injuries constitute a small group within pediatric spinal traumas. Such injuries are seen predominantly in the cervical region, followed by the thoracal region . The latter type of injury is observed mainly among younger children. Lumbar injuries in the infantile age group, either fracture only, or dislocation with or without fracture, are uncommon. In contrast to adult spinal injury, pediatric lumbar spine trauma is more likely to involve the upper rather than the lower lumbar spine .

Research paper thumbnail of Factor X Deficiency Presenting with Bilateral Chronic Subdural Hematoma

Pediatric Neurosurgery, 2010

A 7-month-old male infant was referred to the neurosurgery clinic of our institution with a histo... more A 7-month-old male infant was referred to the neurosurgery clinic of our institution with a history of general malaise and diminished movements on his right side. On admission, he was lethargic and his neurological examination revealed right hemipa-

Research paper thumbnail of Bilateral symptomatic petrous apex effusion

Petrous apex effusions can present with aural fullness, hearing loss and dizziness. Although they... more Petrous apex effusions can present with aural fullness, hearing loss and dizziness. Although they can be followed-up when asymptomatic, clinical management of symptomatic patients is controversial. In this study, we present clinical and radiological findings of a 24-year-old patient with bilateral petrous apex effusion. She had been complaining of bilateral aural fullness and dizziness for 2 years. Radiological examinations revealed bilateral petrous apex effusion. After medical treatment, her symptoms gradually disappeared. In all previous published studies, unilateral petrous apex effusions were reported. To our best knowledge, this is the first patient with trapped fluid in bilateral petrous apex.

Research paper thumbnail of Analysis of MR Imaging of Wrists in Female Patients with Carpal Tunnel Syndrome and Healthy Controls

International Journal of Morphology, 2009

Research paper thumbnail of Endoplasmic reticulum (ER) homeostasis is cycle-dependent and the inflammatory cytokines TNF-α and ILI1β induce er stress by regulating BIP expression in human endometrial ENDOTHELIAL CELLS

Fertility and Sterility, 2011

Research paper thumbnail of Bidirectional regulation of unfolding protein response in human endometrium and endometriosis

Fertility and Sterility, 2010

hours, the cell number was measured with calcein uptake assay and analyzed via a fluorescent plat... more hours, the cell number was measured with calcein uptake assay and analyzed via a fluorescent plate reader at 485/583 nm. Mean values for each treatment (n¼3-8 experiments) were compared with ANOVA test.

Research paper thumbnail of Atypical Clinical Presentation of Idiophatic Thoracic Spinal Cord Herniation

Spine, 2008

Study Design. Case report. Objective. To report an adult female patient with idiopathic spinal co... more Study Design. Case report. Objective. To report an adult female patient with idiopathic spinal cord herniation presenting with pain without symptoms of myelopathy.

Research paper thumbnail of Cervical Spinal Meningioma Mimicking Intramedullary Spinal Tumor

Spine, 2009

Objective. To report a very unusual spinal meningioma, mimicking an intramedullary spinal tumor.

Research paper thumbnail of Pituitary Carcinoma Presenting with Multiple Metastases: Case Report

Journal of Child Neurology, 2008

1 that time had revealed communicating hydrocephalus without evidence of a sellar tumor (Figure 1... more 1 that time had revealed communicating hydrocephalus without evidence of a sellar tumor (Figure 1). However, cranial magnetic resonance (MR) imaging performed on admission did not show shunt dysfunction. P ituitary carcinoma, a rare central nervous system (CNS) tumor seen in adults, represents only about 0.1% to 0.2% of all pituitary tumors. 1-4 Pituitary carcinomas generally present with distant cerebrospinal and/or systemic metastases rather than local invasion. 4 All the cases of pituitary carcinomas in the literature (in English) involve adults. 1,4-7 To our knowledge, ours is the first case of pituitary carcinoma in a pediatric patient.

Research paper thumbnail of Serum neuron-specific enolase as a predictor of short-term outcome and its correlation with Glasgow Coma Scale in traumatic brain injury

Neurosurgical Review, 2008

Elevated serum neuron-specific enolase levels are correlated with brain cell damage. Low scores a... more Elevated serum neuron-specific enolase levels are correlated with brain cell damage. Low scores according to Glasgow Coma Scale are also considered as serious poor prognostic factor. The aims of the study were to investigate whether there is a correlation between the two measurements in patients with traumatic brain injury and whether serum neuron-specific enolase levels have potential as a screening test to predict outcome. A total of 169 consecutive patients with traumatic brain injury admitted to our clinic between 2002 and 2005 are included in this study. Those patients, who had any major health problem before trauma, were excluded from the study. However, patients with isolated head injury were included in the study. Serial serum neuron-specific enolase concentrations taken at the first 2, 24, and 48 h after traumatic brain injury were analyzed. A computed tomography was performed on each patient on admission. Their Glasgow Coma Scale scores were recorded serially. The relationship between Glasgow Coma Scale scores and the serum neuron-specific enolase levels were assessed by statistical methods. There was a significant negative correlation between the serum neuron-specific enolase levels and Glasgow Coma Scale scores. The levels of neuron-specific enolase were significantly higher in the patients who died in 30 days after trauma and whose scores were lower than or equal to 8 points in Glasgow Coma Scale. Although there are several serious limitations of the use of neuron-specific enolase as a biomarker in traumatic brain injury (i.e., hypoperfusion, extracranial trauma, bleeding, liver, or kidney damage also increase the level of neuron-specific enolase), its concentrations may be useful as a practical and helpful screening test to identify neurotrauma patients who are at increased risk and may provide supplementary estimation with radiological and clinical findings.

Research paper thumbnail of CT and MR imaging of chronic subdural haematomas: a comparative study

Questions under study/principles: This study was designed to compare CT and MR appearances of chr... more Questions under study/principles: This study was designed to compare CT and MR appearances of chronic subdural haematomas as well as CT-and MR-guided measurements of haematoma thicknesses.

Research paper thumbnail of Complete L1-L2 Lateral Dislocation without Fracture and Neurologic Deficit in a Child

Pediatric Neurosurgery, 2006

other organs . Sixty percent of pediatric spinal traumas are seen in the cervical region, frequen... more other organs . Sixty percent of pediatric spinal traumas are seen in the cervical region, frequently resulting in fracture-type injury, and in particular, after the age of 8. Dislocation without fracture injuries constitute a small group within pediatric spinal traumas. Such injuries are seen predominantly in the cervical region, followed by the thoracal region . The latter type of injury is observed mainly among younger children. Lumbar injuries in the infantile age group, either fracture only, or dislocation with or without fracture, are uncommon. In contrast to adult spinal injury, pediatric lumbar spine trauma is more likely to involve the upper rather than the lower lumbar spine .

Research paper thumbnail of Factor X Deficiency Presenting with Bilateral Chronic Subdural Hematoma

Pediatric Neurosurgery, 2010

A 7-month-old male infant was referred to the neurosurgery clinic of our institution with a histo... more A 7-month-old male infant was referred to the neurosurgery clinic of our institution with a history of general malaise and diminished movements on his right side. On admission, he was lethargic and his neurological examination revealed right hemipa-

Research paper thumbnail of Bilateral symptomatic petrous apex effusion

Petrous apex effusions can present with aural fullness, hearing loss and dizziness. Although they... more Petrous apex effusions can present with aural fullness, hearing loss and dizziness. Although they can be followed-up when asymptomatic, clinical management of symptomatic patients is controversial. In this study, we present clinical and radiological findings of a 24-year-old patient with bilateral petrous apex effusion. She had been complaining of bilateral aural fullness and dizziness for 2 years. Radiological examinations revealed bilateral petrous apex effusion. After medical treatment, her symptoms gradually disappeared. In all previous published studies, unilateral petrous apex effusions were reported. To our best knowledge, this is the first patient with trapped fluid in bilateral petrous apex.