Mehroz Zain | University of Karachi (original) (raw)
Papers by Mehroz Zain
This research aimed to evaluate the eff ect of S, P minerals and cassava leaves supplementation o... more This research aimed to evaluate the eff ect of S, P minerals and cassava leaves supplementation on utilization of ammoniated palm oil leaves in rumen sheep. The research used randomized block design with fi ve rations as treatments and four groups as replication. The treatments were A= grass as control; B= ammoniated palm oil leaves; C= ammoniated palm oil leaves + 0.4% S and 0.27% P; D= ammoniated palm oil leaves + 5% cassava leaves; and E= ammoniated palm oil leaves +y 0.4% S, 0.27% P and 5% cassava leaves. The parameters measured were dry ma er intake and digestibility of dry ma er and fi ber fraction (NDF, ADF, cellulose, and hemicelluloses). Dietary treatments had not signifi cant eff ect on dry ma er intake but signifi cantly increased dry ma er and fi ber fraction digestibility, especially ADF. Diet E indicated the highest digestibility which supplied the entire nutrient required to growth and optimize activities of rumen microbes.
Jurnal Peternakan Indonesia (Indonesian Journal of Animal Science)
Penelitian ini memiliki tujuan untuk melihat pengaruh pengunaan baglog pelepah sawit fermentasi d... more Penelitian ini memiliki tujuan untuk melihat pengaruh pengunaan baglog pelepah sawit fermentasi dengan jamur (Pleoratus ostreatus) terhadap retensi N dan performa ternak kambing. Penelitian menggunakan metode Rancangan Acak Kelompok (RAK) terdiri dari 4 ulangan dan 4 perlakuan disetiap kombinasi. Perlakuan penelitian ini adalah: A = 0 % Baglog, B = 20 % Baglog, C = 30 % Baglog, dan D = 40 % Baglog. Variabel yang diamati konsumsi BO, konsumsi BK, PBBh dan retensi N. Hasil analisis keragaman menunjukkan bahwa perlakuan (P>0,05) memberikan pengaruh tidak berbeda nyata terhadap komsumsi BO, BK, PBBh dan (P>0,01) memberikan pengaruh yang sangat nyata terhadap retensi N. Dari hasil penelitian ini dapat disimpukan bahwa penggunaan baglog pelepah sawit yang difermentasi jamur (Pleorotus ostreatus) sampai dengan level 40% palatabel dikonsumsi ternak dengan hasil performan ternak dengan nilai konsumsi BK 1946,60 (g/ekor/h), BO 1455,96 (g/ekor/h) dan PBBh 136,25 (g/ekor/h), tetapi berpengaruh terhadap retensi N dengan nilai 6,34 (g/ekor/h).
Materials
In recent years, the increasing level of CO 2 in the atmosphere has not only contributed to globa... more In recent years, the increasing level of CO 2 in the atmosphere has not only contributed to global warming but has also triggered considerable interest in photocatalytic reduction of CO 2. The reduction of CO 2 with H 2 O using sunlight is an innovative way to solve the current growing environmental challenges. This paper reviews the basic principles of photocatalysis and photocatalytic CO 2 reduction, discusses the measures of the photocatalytic efficiency and summarizes current advances in the exploration of this technology using different types of semiconductor photocatalysts, such as TiO 2 and modified TiO 2 , layered-perovskite Ag/ALa 4 Ti 4 O 15 (A = Ca, Ba, Sr), ferroelectric LiNbO 3 , and plasmonic photocatalysts. Visible light harvesting, novel plasmonic photocatalysts offer potential solutions for some of the main drawbacks in this reduction process. Effective plasmonic photocatalysts that have shown reduction activities towards CO 2 with H 2 O are highlighted here. Although this technology is still at an embryonic stage, further studies with standard theoretical and comprehensive format are suggested to develop photocatalysts with high production rates and selectivity. Based on the collected results, the immense prospects and opportunities that exist in this technique are also reviewed here.
West Indian Medical Journal, 2016
This study examines the impact of corporate governance mechanisms namely audit committee characte... more This study examines the impact of corporate governance mechanisms namely audit committee characteristics, internal audit arrangements, and managerial ownership on external audit fees. Using a sample of 539 firms listed on the main board, the results of the study document a positive relationship between audit committee independence and audit fees. Consistent with the capital reputational theory, the result suggests that independent audit committee demand for higher quality audit in order to protect their capital reputation as an expert. Contrary to our prediction, this study documents a negative relationship between audit committee expertise and audit fees indicating that auditors perceived firms with more audit committee members that possess accounting and finance expertise to be less risky and thus charged less audit fees to these firms. Furthermore, findings indicate that firms with their own internal audit function pay higher audit fees in comparison to those firms that outsourced their internal audit activities. Consistent with agency theory, the result suggests that the demand for audit services would be lower for firms whose managers own higher percentage of shares due to lower agency cost as compared to those firms with higher outsiders" ownership.
Applied Mechanics and Materials, 2014
Shrimp culture is the fastest growing sector of the aquaculture industry in Malaysia. In culturin... more Shrimp culture is the fastest growing sector of the aquaculture industry in Malaysia. In culturing tiger prawn, the pH level needed for water is around 7.0-8.5. Currently, prawn farmer in Malaysia still using a manual method to control the water pH level by adding chemical (Lime), in which, the process required constant monitoring and control by labor. Since the prawns are so sensitive on pH level, an automatic pH control system is required to maintain the water pH automatically and precisely. This research was conducted to design a system that can control and provide feedback on the changes of pH level and been implemented at the reservoir tank that can act as water storage tank and prawn pond. Control system and pH sensor are the important components in controlling the pH level. Input from pH sensor was processed by controller. Moreover, after an error is detected by controller, the correction will be delivered to the system as a feedback process. Nitric acid with concentration of...
Applied Mechanics and Materials, 2013
Food and feeding become a major challenge in aquaculture development. The way adjustment of food ... more Food and feeding become a major challenge in aquaculture development. The way adjustment of food delivery to pond is an important role to get the maximum return or profit to aquaculture entrepreneurs. This project presents an investigation about the fish feeding system, a system device to feed fish at predetermined amounts of food and time. Moreover, the system is designed with a computer monitored system in order to manage and control the system with simulation. This project is a simulation investigation into the development of PID controller using Matlab/Simulink software. The simulation development of the PID controller with the mathematical model of fish feeder system is done using trial and error method. The PID parameter is to be tested with a DC motor. As a result, the best value of PID controller is achieved when Kp = 100, Ki = 0.05 and Kd = 25.
Journal of Applied Sciences, 2008
Thunderbird International Business Review, 2006
In today's globalization era, more and more firms are striving to have an international pres... more In today's globalization era, more and more firms are striving to have an international presence, even though they face many challenges. Based on a multisite case study method, this article examines how indigenous Malaysian small and medium-sized enterprises (SMEs) use their network relationships to facilitate their internationalization process. The evidence from the case of three software firms and one control firm in this study support the firms' internationalization process in the ways that network relationships trigger and motivate them to internationalize, influence their marketselection decision and mode-of-entry decision, help them gain initial credibility, allow access to additional relationships and established channels, help in lowering cost and reducing risk, and influence their internationalization pace and pattern. © 2006 Wiley Periodicals, Inc.
Indian Journal of Pediatrics, 1995
Blood samples from 813 newborns were spotted on to filter paper and the 17-hydroxyprogesterone co... more Blood samples from 813 newborns were spotted on to filter paper and the 17-hydroxyprogesterone concentration was measured using the Delfia (R) fluorometric immunoassay. The median, mean, and standard deviation (SD) for the total population were 20, 21 and (11) nmol/L respectively. Males had significantly higher levels than females with median, mean and (SD) of 22, 22 and (12) nmol/L. Similarly, low birth weight babies were found to have significantly higher levels than normal birth weight babies with median, mean and (SD) of 21, 24 (12) nmol/L. Preterm babies were also found to have significantly higher levels than full term babies, with median, mean and (SD) of 25, 29 (16) nmol/L. As experienced elsewhere, those factors should be taken into consideration when considering a cut-off point in any neonatal screening program for congenital adrenal hyperplasia.
Cement and Concrete Research, 2002
Splitting tensile strength (STS) is one of the concrete mechanical properties that are used in st... more Splitting tensile strength (STS) is one of the concrete mechanical properties that are used in structural design. It can be related to numerous parameters, which include compressive strength, water/binder (W/B) ratio and concrete age. Until now, most researchers estimated the STS directly from compressive strength data. This paper suggests formulae that relate STS with that of compressive strength, W/B ratio
2010 International Conference on Intelligent and Advanced Systems, 2010
Ultrasound imaging is one of the imaging techniques that commonly used in the medical imaging bes... more Ultrasound imaging is one of the imaging techniques that commonly used in the medical imaging beside x-ray, MRI and CT scan. It is a technique that provides noninvasive, nondestructive and also low cost for imaging. However, ultrasound imaging will afford images with a speckle noise which make the images unclear and this is a failing of ultrasound. Therefore, to enhance the ultrasound images of long bone fracture, a study was carried out and it involved contrast enhancement of the image using filtering techniques such as Average, Median and Wiener Filters for the speckle reduction. The level of improvement obtained through these three filtering techniques is discussed in this paper. Amongst the three techniques, the Wiener Filtering is a better technique in reducing the speckle without fully eliminating the image edges. It was found through visual inspection and histogram analysis.
… journal of cancer, 1992
NIH-3T3 cells are non-tumorigenic when injected into athymic mice. If these cells are mixed with ... more NIH-3T3 cells are non-tumorigenic when injected into athymic mice. If these cells are mixed with an extract of basementmembrane proteins (matrigel) and injected s.c., they form locally invasive and highly vascularized tumors. Cells cultured from the NIH-3T3-matrigel-induced tumors showed a transformed phenotype and lacked contact inhibition. When cultured in a gel of matrigel, they proliferated and formed branched and invasive colonies. In contrast, the parental NIH-3T3 cells cultured on matrigel remained as cell aggregates and were not invasive. I.V. injections of the tumor-derived NIH-3T3 cells produced many colonies on the surface of the lungs, whereas the parental NIH-3T3 cells were not metastatic. Zymographic analysis of the conditioned media obtained from both the tumor-derived and parental NIH-3T3 cells demonstrated higher amounts of the 72-kDa gelatinase (type-IV collagenase) enzyme in the tumor-derived cells. Also, tumorderived NIH-3T3 cells, but not parental NIH-3T3 cells, secreted the 92-kDa type-IV collagenase. These studies suggest that the interaction of pre-malignant NIH-3T3 cells with extracellular matrix components may contribute to the process of tumor progression.
Retinoic acid is a lipophilic derivative of vitamin A that can cause differentiation in a variety... more Retinoic acid is a lipophilic derivative of vitamin A that can cause differentiation in a variety of cell types. A large body of evidence has shown that normal retinoid signaling is required for proper neutrophil maturation in vitro and in vivo. In this study, we have found that calcium/calmodulin dependent (CaM) protein kinase kinase ␣ (CaMKK ␣) is upregulated in an immediate early fashion during retinoic acid induced neutrophil maturation. Furthermore, we describe the expression and modulation of various components of the CaM kinase cascade during neutrophil maturation. We have confirmed upregulation of CaMKK ␣ protein by Western analysis and further show that CaMKK  is expressed, although its protein levels are constant throughout induction. We also find that neutrophil progenitor cells express both CaMKI and CaMKIV transcripts. RNase protection and Western analysis show that CaMKIV is downregulated during neutrophil maturation. In contrast, CaMKI transcript and protein is expressed in uninduced cells and is induced by all-trans retinoic acid. These data represent the first report of a CaM kinase cascade in myeloid cells and suggests that this cascade may mediate some of the well-characterized effects of calcium on neutrophil function. These observations also support the idea that the retinoic acid receptors play a major role in mediating neutrophil specific gene expression and differentiation.
31 SIMULATION OF SUSPENSION SYSTEM WITH ADAPTIVE FUZZY ACTIVE FORCE CONTROL Priyandoko G. & Maila... more 31 SIMULATION OF SUSPENSION SYSTEM WITH ADAPTIVE FUZZY ACTIVE FORCE CONTROL Priyandoko G. & Mailah M. Department of Applied Mechanics, Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia E-mail: ...
Environmentally plant is a young tree, shrub or herb for planting. Imru al-Qays the pre-Islamic p... more Environmentally plant is a young tree, shrub or herb for planting. Imru al-Qays the pre-Islamic poet has poetically versed the description of the plants in many hemistichs. It hemistically can be compartmentalized into several categories, cloves, colocynth, henna, moss, onion, pepper, trees acacia, aloe, dal, jujube, palm and tamarisk. He has carefully portrayed the sweet smell of his beloved as a gentle breeze of the east wind arriving with the sweet smell of cloves.
Acta Crystallographica Section C: Crystal Structure Communications, 2004
The title compound, C9H13NO3S2, exists as a zwitterion with crystallographic mirror symmetry. The... more The title compound, C9H13NO3S2, exists as a zwitterion with crystallographic mirror symmetry. The central S atom of the S2O3 group adopts a slightly distorted tetrahedral coordination geometry. The S-S bond length is 2.1137 (7) Å, while the S-O bond lengths are in the range 1.4417 (12)-1.457 (2) Å. The zwitterions in the crystal adopt a head-to-tail arrangement, which leads to the formation of a three-dimensional network through C-H ⋯ O hydrogen bonds.
BMC Medical …, 2012
Background: One of the genes suggested to play an important role in the pathophysiology of bipola... more Background: One of the genes suggested to play an important role in the pathophysiology of bipolar disorder (BPD) is PDLIM5, which encodes LIM domain protein. Our main objective was to examine the effect of olanzapine treatment on PDLIM5 mRNA expression in the peripheral blood leukocytes of BPD patients.Methods: We measured the expression of PDLIM5 mRNA from 16 patients with BPD Type I after 0, 4, and 8 weeks of treatment with olanzapine using quantitative real-time PCR. The Young Mania Rating Scale was used to evaluate the severity of manic symptoms in BPD patients. We also compared PDLIM5 mRNA expression in treatment-naïve BPD patients with that in healthy control subjects.Results: No significant difference was found in PDLIM5 mRNA expression between patients before olanzapine treatment and following 4 and 8 weeks of treatment (p>0.05). Although we observed a significant reduction in the severity of manic symptoms in all BPD patients (p<0.05), the effectiveness of the medica...
This research aimed to evaluate the eff ect of S, P minerals and cassava leaves supplementation o... more This research aimed to evaluate the eff ect of S, P minerals and cassava leaves supplementation on utilization of ammoniated palm oil leaves in rumen sheep. The research used randomized block design with fi ve rations as treatments and four groups as replication. The treatments were A= grass as control; B= ammoniated palm oil leaves; C= ammoniated palm oil leaves + 0.4% S and 0.27% P; D= ammoniated palm oil leaves + 5% cassava leaves; and E= ammoniated palm oil leaves +y 0.4% S, 0.27% P and 5% cassava leaves. The parameters measured were dry ma er intake and digestibility of dry ma er and fi ber fraction (NDF, ADF, cellulose, and hemicelluloses). Dietary treatments had not signifi cant eff ect on dry ma er intake but signifi cantly increased dry ma er and fi ber fraction digestibility, especially ADF. Diet E indicated the highest digestibility which supplied the entire nutrient required to growth and optimize activities of rumen microbes.
Jurnal Peternakan Indonesia (Indonesian Journal of Animal Science)
Penelitian ini memiliki tujuan untuk melihat pengaruh pengunaan baglog pelepah sawit fermentasi d... more Penelitian ini memiliki tujuan untuk melihat pengaruh pengunaan baglog pelepah sawit fermentasi dengan jamur (Pleoratus ostreatus) terhadap retensi N dan performa ternak kambing. Penelitian menggunakan metode Rancangan Acak Kelompok (RAK) terdiri dari 4 ulangan dan 4 perlakuan disetiap kombinasi. Perlakuan penelitian ini adalah: A = 0 % Baglog, B = 20 % Baglog, C = 30 % Baglog, dan D = 40 % Baglog. Variabel yang diamati konsumsi BO, konsumsi BK, PBBh dan retensi N. Hasil analisis keragaman menunjukkan bahwa perlakuan (P>0,05) memberikan pengaruh tidak berbeda nyata terhadap komsumsi BO, BK, PBBh dan (P>0,01) memberikan pengaruh yang sangat nyata terhadap retensi N. Dari hasil penelitian ini dapat disimpukan bahwa penggunaan baglog pelepah sawit yang difermentasi jamur (Pleorotus ostreatus) sampai dengan level 40% palatabel dikonsumsi ternak dengan hasil performan ternak dengan nilai konsumsi BK 1946,60 (g/ekor/h), BO 1455,96 (g/ekor/h) dan PBBh 136,25 (g/ekor/h), tetapi berpengaruh terhadap retensi N dengan nilai 6,34 (g/ekor/h).
Materials
In recent years, the increasing level of CO 2 in the atmosphere has not only contributed to globa... more In recent years, the increasing level of CO 2 in the atmosphere has not only contributed to global warming but has also triggered considerable interest in photocatalytic reduction of CO 2. The reduction of CO 2 with H 2 O using sunlight is an innovative way to solve the current growing environmental challenges. This paper reviews the basic principles of photocatalysis and photocatalytic CO 2 reduction, discusses the measures of the photocatalytic efficiency and summarizes current advances in the exploration of this technology using different types of semiconductor photocatalysts, such as TiO 2 and modified TiO 2 , layered-perovskite Ag/ALa 4 Ti 4 O 15 (A = Ca, Ba, Sr), ferroelectric LiNbO 3 , and plasmonic photocatalysts. Visible light harvesting, novel plasmonic photocatalysts offer potential solutions for some of the main drawbacks in this reduction process. Effective plasmonic photocatalysts that have shown reduction activities towards CO 2 with H 2 O are highlighted here. Although this technology is still at an embryonic stage, further studies with standard theoretical and comprehensive format are suggested to develop photocatalysts with high production rates and selectivity. Based on the collected results, the immense prospects and opportunities that exist in this technique are also reviewed here.
West Indian Medical Journal, 2016
This study examines the impact of corporate governance mechanisms namely audit committee characte... more This study examines the impact of corporate governance mechanisms namely audit committee characteristics, internal audit arrangements, and managerial ownership on external audit fees. Using a sample of 539 firms listed on the main board, the results of the study document a positive relationship between audit committee independence and audit fees. Consistent with the capital reputational theory, the result suggests that independent audit committee demand for higher quality audit in order to protect their capital reputation as an expert. Contrary to our prediction, this study documents a negative relationship between audit committee expertise and audit fees indicating that auditors perceived firms with more audit committee members that possess accounting and finance expertise to be less risky and thus charged less audit fees to these firms. Furthermore, findings indicate that firms with their own internal audit function pay higher audit fees in comparison to those firms that outsourced their internal audit activities. Consistent with agency theory, the result suggests that the demand for audit services would be lower for firms whose managers own higher percentage of shares due to lower agency cost as compared to those firms with higher outsiders" ownership.
Applied Mechanics and Materials, 2014
Shrimp culture is the fastest growing sector of the aquaculture industry in Malaysia. In culturin... more Shrimp culture is the fastest growing sector of the aquaculture industry in Malaysia. In culturing tiger prawn, the pH level needed for water is around 7.0-8.5. Currently, prawn farmer in Malaysia still using a manual method to control the water pH level by adding chemical (Lime), in which, the process required constant monitoring and control by labor. Since the prawns are so sensitive on pH level, an automatic pH control system is required to maintain the water pH automatically and precisely. This research was conducted to design a system that can control and provide feedback on the changes of pH level and been implemented at the reservoir tank that can act as water storage tank and prawn pond. Control system and pH sensor are the important components in controlling the pH level. Input from pH sensor was processed by controller. Moreover, after an error is detected by controller, the correction will be delivered to the system as a feedback process. Nitric acid with concentration of...
Applied Mechanics and Materials, 2013
Food and feeding become a major challenge in aquaculture development. The way adjustment of food ... more Food and feeding become a major challenge in aquaculture development. The way adjustment of food delivery to pond is an important role to get the maximum return or profit to aquaculture entrepreneurs. This project presents an investigation about the fish feeding system, a system device to feed fish at predetermined amounts of food and time. Moreover, the system is designed with a computer monitored system in order to manage and control the system with simulation. This project is a simulation investigation into the development of PID controller using Matlab/Simulink software. The simulation development of the PID controller with the mathematical model of fish feeder system is done using trial and error method. The PID parameter is to be tested with a DC motor. As a result, the best value of PID controller is achieved when Kp = 100, Ki = 0.05 and Kd = 25.
Journal of Applied Sciences, 2008
Thunderbird International Business Review, 2006
In today's globalization era, more and more firms are striving to have an international pres... more In today's globalization era, more and more firms are striving to have an international presence, even though they face many challenges. Based on a multisite case study method, this article examines how indigenous Malaysian small and medium-sized enterprises (SMEs) use their network relationships to facilitate their internationalization process. The evidence from the case of three software firms and one control firm in this study support the firms' internationalization process in the ways that network relationships trigger and motivate them to internationalize, influence their marketselection decision and mode-of-entry decision, help them gain initial credibility, allow access to additional relationships and established channels, help in lowering cost and reducing risk, and influence their internationalization pace and pattern. © 2006 Wiley Periodicals, Inc.
Indian Journal of Pediatrics, 1995
Blood samples from 813 newborns were spotted on to filter paper and the 17-hydroxyprogesterone co... more Blood samples from 813 newborns were spotted on to filter paper and the 17-hydroxyprogesterone concentration was measured using the Delfia (R) fluorometric immunoassay. The median, mean, and standard deviation (SD) for the total population were 20, 21 and (11) nmol/L respectively. Males had significantly higher levels than females with median, mean and (SD) of 22, 22 and (12) nmol/L. Similarly, low birth weight babies were found to have significantly higher levels than normal birth weight babies with median, mean and (SD) of 21, 24 (12) nmol/L. Preterm babies were also found to have significantly higher levels than full term babies, with median, mean and (SD) of 25, 29 (16) nmol/L. As experienced elsewhere, those factors should be taken into consideration when considering a cut-off point in any neonatal screening program for congenital adrenal hyperplasia.
Cement and Concrete Research, 2002
Splitting tensile strength (STS) is one of the concrete mechanical properties that are used in st... more Splitting tensile strength (STS) is one of the concrete mechanical properties that are used in structural design. It can be related to numerous parameters, which include compressive strength, water/binder (W/B) ratio and concrete age. Until now, most researchers estimated the STS directly from compressive strength data. This paper suggests formulae that relate STS with that of compressive strength, W/B ratio
2010 International Conference on Intelligent and Advanced Systems, 2010
Ultrasound imaging is one of the imaging techniques that commonly used in the medical imaging bes... more Ultrasound imaging is one of the imaging techniques that commonly used in the medical imaging beside x-ray, MRI and CT scan. It is a technique that provides noninvasive, nondestructive and also low cost for imaging. However, ultrasound imaging will afford images with a speckle noise which make the images unclear and this is a failing of ultrasound. Therefore, to enhance the ultrasound images of long bone fracture, a study was carried out and it involved contrast enhancement of the image using filtering techniques such as Average, Median and Wiener Filters for the speckle reduction. The level of improvement obtained through these three filtering techniques is discussed in this paper. Amongst the three techniques, the Wiener Filtering is a better technique in reducing the speckle without fully eliminating the image edges. It was found through visual inspection and histogram analysis.
… journal of cancer, 1992
NIH-3T3 cells are non-tumorigenic when injected into athymic mice. If these cells are mixed with ... more NIH-3T3 cells are non-tumorigenic when injected into athymic mice. If these cells are mixed with an extract of basementmembrane proteins (matrigel) and injected s.c., they form locally invasive and highly vascularized tumors. Cells cultured from the NIH-3T3-matrigel-induced tumors showed a transformed phenotype and lacked contact inhibition. When cultured in a gel of matrigel, they proliferated and formed branched and invasive colonies. In contrast, the parental NIH-3T3 cells cultured on matrigel remained as cell aggregates and were not invasive. I.V. injections of the tumor-derived NIH-3T3 cells produced many colonies on the surface of the lungs, whereas the parental NIH-3T3 cells were not metastatic. Zymographic analysis of the conditioned media obtained from both the tumor-derived and parental NIH-3T3 cells demonstrated higher amounts of the 72-kDa gelatinase (type-IV collagenase) enzyme in the tumor-derived cells. Also, tumorderived NIH-3T3 cells, but not parental NIH-3T3 cells, secreted the 92-kDa type-IV collagenase. These studies suggest that the interaction of pre-malignant NIH-3T3 cells with extracellular matrix components may contribute to the process of tumor progression.
Retinoic acid is a lipophilic derivative of vitamin A that can cause differentiation in a variety... more Retinoic acid is a lipophilic derivative of vitamin A that can cause differentiation in a variety of cell types. A large body of evidence has shown that normal retinoid signaling is required for proper neutrophil maturation in vitro and in vivo. In this study, we have found that calcium/calmodulin dependent (CaM) protein kinase kinase ␣ (CaMKK ␣) is upregulated in an immediate early fashion during retinoic acid induced neutrophil maturation. Furthermore, we describe the expression and modulation of various components of the CaM kinase cascade during neutrophil maturation. We have confirmed upregulation of CaMKK ␣ protein by Western analysis and further show that CaMKK  is expressed, although its protein levels are constant throughout induction. We also find that neutrophil progenitor cells express both CaMKI and CaMKIV transcripts. RNase protection and Western analysis show that CaMKIV is downregulated during neutrophil maturation. In contrast, CaMKI transcript and protein is expressed in uninduced cells and is induced by all-trans retinoic acid. These data represent the first report of a CaM kinase cascade in myeloid cells and suggests that this cascade may mediate some of the well-characterized effects of calcium on neutrophil function. These observations also support the idea that the retinoic acid receptors play a major role in mediating neutrophil specific gene expression and differentiation.
31 SIMULATION OF SUSPENSION SYSTEM WITH ADAPTIVE FUZZY ACTIVE FORCE CONTROL Priyandoko G. & Maila... more 31 SIMULATION OF SUSPENSION SYSTEM WITH ADAPTIVE FUZZY ACTIVE FORCE CONTROL Priyandoko G. & Mailah M. Department of Applied Mechanics, Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia E-mail: ...
Environmentally plant is a young tree, shrub or herb for planting. Imru al-Qays the pre-Islamic p... more Environmentally plant is a young tree, shrub or herb for planting. Imru al-Qays the pre-Islamic poet has poetically versed the description of the plants in many hemistichs. It hemistically can be compartmentalized into several categories, cloves, colocynth, henna, moss, onion, pepper, trees acacia, aloe, dal, jujube, palm and tamarisk. He has carefully portrayed the sweet smell of his beloved as a gentle breeze of the east wind arriving with the sweet smell of cloves.
Acta Crystallographica Section C: Crystal Structure Communications, 2004
The title compound, C9H13NO3S2, exists as a zwitterion with crystallographic mirror symmetry. The... more The title compound, C9H13NO3S2, exists as a zwitterion with crystallographic mirror symmetry. The central S atom of the S2O3 group adopts a slightly distorted tetrahedral coordination geometry. The S-S bond length is 2.1137 (7) Å, while the S-O bond lengths are in the range 1.4417 (12)-1.457 (2) Å. The zwitterions in the crystal adopt a head-to-tail arrangement, which leads to the formation of a three-dimensional network through C-H ⋯ O hydrogen bonds.
BMC Medical …, 2012
Background: One of the genes suggested to play an important role in the pathophysiology of bipola... more Background: One of the genes suggested to play an important role in the pathophysiology of bipolar disorder (BPD) is PDLIM5, which encodes LIM domain protein. Our main objective was to examine the effect of olanzapine treatment on PDLIM5 mRNA expression in the peripheral blood leukocytes of BPD patients.Methods: We measured the expression of PDLIM5 mRNA from 16 patients with BPD Type I after 0, 4, and 8 weeks of treatment with olanzapine using quantitative real-time PCR. The Young Mania Rating Scale was used to evaluate the severity of manic symptoms in BPD patients. We also compared PDLIM5 mRNA expression in treatment-naïve BPD patients with that in healthy control subjects.Results: No significant difference was found in PDLIM5 mRNA expression between patients before olanzapine treatment and following 4 and 8 weeks of treatment (p>0.05). Although we observed a significant reduction in the severity of manic symptoms in all BPD patients (p<0.05), the effectiveness of the medica...