Mahmut Gür | Kastamonu University (original) (raw)
Papers by Mahmut Gür
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Luminescence, Aug 10, 2023
Organic compounds containing phenanthroimidazole, and its optical, thermal, chemical, and high fl... more Organic compounds containing phenanthroimidazole, and its optical, thermal, chemical, and high fluorescence, have drawn the interest of numerous researchers. Phenanthroimidazole derivatives are appealing for various applications due to these characteristics. This research provides a summary of the general information contained in studies on the synthesis, characterization, photophysical characteristics, and possible applications of phenanthroimidazole derivative compounds. The focus of this study revolves around the topic of utilization in technological fields such as sensors, solar cells, optical brighteners, and organic light‐emitting diodes, and covers significant studies on mentioned topics. We anticipate that this study will provide an outline for researchers aiming to further examine fluorescent organic compounds for technological innovations. Furthermore, we anticipate that this research will be crucial in developing long‐term high‐organic compounds for optoelectronic devices.
Journal of Fluorescence, Mar 24, 2022
Phenanthroimidazole-thiadiazole hybrid derivatives, which are new heterocyclic compounds with flu... more Phenanthroimidazole-thiadiazole hybrid derivatives, which are new heterocyclic compounds with fluorescence properties, were synthesized by designing a two-step reaction mechanism and their photophysical properties were investigated. The synthesized derivatives were purified and their structures were elucidated by ATR-IR, 1H-NMR, elemental analysis and HR-MS methods. In the next stage of the study, the absorption and emission spectra of the synthesized new phenanthroimidazole-thiadiazole hybrid derivatives were determined by UV-Vis and fluorescence spectroscopy. Stokes' shifts, molar extinction coefficients (ε), singlet energy levels (Es), quantum yield (ϕf), lifetimes (τ), the radiative (kr) and the nonradiative (knr) constant for new hybrid derivatives were measured in DMSO. In addition, aggregation measurements, which is an important parameter that changes the photophysical properties were performed and for these compounds, structure: photophysical properties were discussed.
Gazi Üniversitesi Orman Fakültesi dergisi, Apr 3, 2021
Aim of Study: It was aimed to determine the chemical composition, antioxidant and antibacterial a... more Aim of Study: It was aimed to determine the chemical composition, antioxidant and antibacterial activity of the Thymus praecox which distributed in the Kastamonu region. Material and methods: Spectroscopic and chromotographic analysis were applied in the determination of the chemical composition. Thyme extracts were prepared using five different solvents. In Thymus praecox, the presence of flavonoids using HPLC and the chemical content of essential oil using GC-MS were investigated. The analyses of the mineral were determined in leaf and stem of thyme by ICP-OES. Antioxidant capacity was determined using two methods such as DPPH free radical scavenging and H2O2 scavenging. Antibacterial activity on ten bacteria, Gram (+) and Gram (-) was tested using the disc diffusion method. Main results: Experimental results showed that thyme extracts have antibacterial activities against some bacteria. As a result, it was found that the most affected bacteria was S. aureus. Inhibition zone diameter was determined to be between 8-12 mm. The effect of solvent on antibacterial activity, antioxidant capacity, total phenolic and total flavonoid amounts were observed. Highlights: These results showed that T. praecox has the potential to be used as a natural antimicrobial and antioxidant agent, and can be used as a natural supportive treatment.
After the synthesis of the new benzimidazole derivative 1,3,4-thiadiazole compound, a series of a... more After the synthesis of the new benzimidazole derivative 1,3,4-thiadiazole compound, a series of azo dyes from the reaction of this compound with various coupling components and a series of schiff bases were synthesized from the reaction with various aldehydes. The structures of the obtained compounds are characterized and interpreted with UV, FT-IR and 1 H-NMR. The fluorescence properties of the compounds were also investigated, and the absorption and emission properties of schiff base and azo dyes obtained from the same derivative were examined. As a result, it was observed that schiff bases obtained from benzimidazole derivative 1,3,4thiadiazole compound had longer wavelength absorption-emission compared to azo dyes obtained from the same compound. Experimental data were supported by density functional theory (DFT) calculations. The ground state geometries, spectroscopic properties, FMO energies and related chemical reactivity parameters of the compounds were calculated using the B3LYP hybrid density functional combined with 6-311++G(2d,2p) basis set. At the same theory level, QTAIM and IRI analyzes were also performed and the data were used to determine the properties of tautomeric structures. The electronic properties of the compounds were studied and a detailed analysis was performed by comparing them with experimental data.
In the study, the active drugs molecules used in the treatment of convulsive seizures occurring i... more In the study, the active drugs molecules used in the treatment of convulsive seizures occurring in epilepsy disease were used.
Hitite journal of science and engineering, May 10, 2023
W hen the studies are examined, it has been seen that heterocyclic molecules are generally used f... more W hen the studies are examined, it has been seen that heterocyclic molecules are generally used for the biological activity tests of the compounds. Thiadiazole rings containing two nitrogens and one sulphur atom are very popular compounds for such studies. In particular, the 1,3,4-thiadiazole isomers are the prominent derivatives in the thiadiazole class in terms of their pharmacological properties. 1,3,4-thiadiazole molecules and their derivatives possess a wide range of pharmacological activities like anticancer/antitumor (1,2), anticonvulsant (3,4), antidiabetic (5,6), anti-inflammatory (7,8), antidepressant (9), antihypertensive (10), antiviral (11,12), antileishmanial (13,14), antimicrobial (15,16) and many more. Among these studies, the most common pharmacological feature is antimicrobial studies. Because of the over/ misuse of antibiotics, antibiotic resistance caused by microorganisms is now recognized as a serious global threat. As a precaution against this situation, studies are being carried out for developing novel agents that
HAL (Le Centre pour la Communication Scientifique Directe), 2016
Optical Materials, Apr 1, 2023
Gazi Üniversitesi Orman Fakültesi dergisi, Sep 15, 2018
Aim of study: The objectives in this study were to determine the chemical composition and antimic... more Aim of study: The objectives in this study were to determine the chemical composition and antimicrobial activity of the essential oils from nutmeg (Myristica fragrans) and cardamom (Elettaria cardamomum). Material and Methods: The essential oil was obtained from nutmeg and cardamom seeds through hydrodistillation method. The chemical composition of nutmeg and cardamom essential oil was analyzed by GC-MS. The antimicrobial activity of essential oil was investigated against
Journal of Molecular Structure, Dec 1, 2018
Hetero-crown ethers (ligands I-IV) containing 1,3,4-thiadiazole-2,5-dithiol (bismuthiol) were syn... more Hetero-crown ethers (ligands I-IV) containing 1,3,4-thiadiazole-2,5-dithiol (bismuthiol) were synthesized and fully characterized. The ligands were prepared by a nucleophilic substitution (S N 2) reaction of the appropriate ethylene glycol dihalide derivatives with 1,3,4-thiadiazole-2,5-dithiol dipotassium salt under highly diluted conditions, and subsequent ring closure. Complexation constants and selectivity factors for these heterocyclic ligands in dichloromethane or chloroform were determined by ion-pair extraction from an aqueous solution containing
Indian Journal of Pharmaceutical Education and Research, Jul 25, 2017
Essential oils were obtained from Coriandrum sativum and Alpinia officinarum through steam distil... more Essential oils were obtained from Coriandrum sativum and Alpinia officinarum through steam distillation method in this study. Antimicrobial activities of the obtained essential oils were investigated by using minimum inhibitory concentration (MIC) test by against 18 different species microorganisms. It was found that the C. sativum had strong antimicrobial activities against the 14 tested microorganism and A. officinarum oils showed strong antimicrobial activity against the 7 tested microorganisms. Furthermore, the contents of the essential oils were determined with GC-MS analyses. The most abundant compounds of essential oils of A. officinarum and C. sativum were determined as 28.4% eucalyptol and 69.4% linalool. As a result, it can be easily said that the essential oils of C. sativum and A. officinarum can be used as antimicrobial protector in related fields.
New Journal of Chemistry, 2021
A novel phenanthroimidazole derivative with p-type conductivity was prepared and fabricated as a ... more A novel phenanthroimidazole derivative with p-type conductivity was prepared and fabricated as a heterostructure, exhibiting a negative differential resistance and photodiode properties.
Journal of Molecular Structure, Apr 1, 2017
In this study, 4,7-dihydrotetrazolo[1, 5-a]pyrimidine derivatives (1-5) were prepared via Multico... more In this study, 4,7-dihydrotetrazolo[1, 5-a]pyrimidine derivatives (1-5) were prepared via Multicomponent Cyclocondensation Reactions (MCRs). All structures were determined by using FT-IR, 1 H/ 13 C NMR and elemental analyses. The compounds were investigated as corrosion inhibitors using density functional theory (DFT) at the level of B3LYP/6-31G (d, p). According to the calculations, compound 1 appears to be a good inhibitor for corrosion. In addition, the electrochemical properties of the novel systems were investigated by CV.
Journal of Heterocyclic Chemistry, Jan 22, 2019
Journal of Heterocyclic Chemistry, Sep 14, 2017
Gazi Üniversitesi Orman Fakültesi dergisi, Dec 28, 2018
Aim of study: The aim of this study is to put forward the antimicrobial activity of cold pressed ... more Aim of study: The aim of this study is to put forward the antimicrobial activity of cold pressed oils obtained from seeds of nettle (Urtica dioica), radish (Raphanus sativus) and pomegranate (Punica granatum). Material and Methods: Oils of these seeds were analysed for their antibacterial and antifungal activities by the disk diffusion and MIC tests against fifteen microorganisms,
El-cezeri, Apr 17, 2023
This study includes the structure-activity relationship of active molecules that are commonly use... more This study includes the structure-activity relationship of active molecules that are commonly used in the treatment of convulsive seizures in epileptic diseases. Well-known epileptic active molecules studied are:
Journal of Molecular Structure, Mar 1, 2020
A combined experimental and computational study of a ruthenium(II) polypyridyl complex: Synthesis... more A combined experimental and computational study of a ruthenium(II) polypyridyl complex: Synthesis, characterization, electronic structures and spectral properties,
![Research paper thumbnail of Yeni Floresan 5-(4-(1H-fenantro[9,10-d]imidazol- 2-il)fenil)-2,4-diklorofenil-1,3,4-tiyadiazol-2-amin’in Karakterizasyon Çalışmaları, Fotofiziksel ve Agregasyon Emisyon Özellikleri](https://attachments.academia-assets.com/107966041/thumbnails/1.jpg)
](Journal of characterization, 2023
Thanks to their chemical, thermal, photophysical, and photochemical properties, phenanthroimidazo... more Thanks to their chemical, thermal, photophysical, and photochemical properties, phenanthroimidazole derivative compounds attract attention in optoelectronic device technology, especially in OLEDs. For this reason, phenanthroimidazole derivatives are the most promising compounds for these applications in the future. In this study, the-diCl bearing phenanthroimidazole compound was synthesized, characterized, and investigated in detail the photophysical and aggregation properties. Spectroscopic studies for its characterization used 1 H-NMR, ATR-IR, and detailed LCMS-MS (mass and product ion scan). The absorption and emission spectra of diCl-PHN have been recorded with solvents of different polarities at room temperature. diCl-PHN exhibit high fluorescence quantum yield in DMSO with 0.78. CIE chromaticity diagram results of diCl-PHN were obtained and displayed good intensity. Additionally, aggregation properties were recorded at seven different water concentrations (water/DMSO %). With the results obtained from the study, it was concluded that this phenanthroimidazole derivative compound is a suitable molecule for fluorescent applications.
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Luminescence, Aug 10, 2023
Organic compounds containing phenanthroimidazole, and its optical, thermal, chemical, and high fl... more Organic compounds containing phenanthroimidazole, and its optical, thermal, chemical, and high fluorescence, have drawn the interest of numerous researchers. Phenanthroimidazole derivatives are appealing for various applications due to these characteristics. This research provides a summary of the general information contained in studies on the synthesis, characterization, photophysical characteristics, and possible applications of phenanthroimidazole derivative compounds. The focus of this study revolves around the topic of utilization in technological fields such as sensors, solar cells, optical brighteners, and organic light‐emitting diodes, and covers significant studies on mentioned topics. We anticipate that this study will provide an outline for researchers aiming to further examine fluorescent organic compounds for technological innovations. Furthermore, we anticipate that this research will be crucial in developing long‐term high‐organic compounds for optoelectronic devices.
Journal of Fluorescence, Mar 24, 2022
Phenanthroimidazole-thiadiazole hybrid derivatives, which are new heterocyclic compounds with flu... more Phenanthroimidazole-thiadiazole hybrid derivatives, which are new heterocyclic compounds with fluorescence properties, were synthesized by designing a two-step reaction mechanism and their photophysical properties were investigated. The synthesized derivatives were purified and their structures were elucidated by ATR-IR, 1H-NMR, elemental analysis and HR-MS methods. In the next stage of the study, the absorption and emission spectra of the synthesized new phenanthroimidazole-thiadiazole hybrid derivatives were determined by UV-Vis and fluorescence spectroscopy. Stokes' shifts, molar extinction coefficients (ε), singlet energy levels (Es), quantum yield (ϕf), lifetimes (τ), the radiative (kr) and the nonradiative (knr) constant for new hybrid derivatives were measured in DMSO. In addition, aggregation measurements, which is an important parameter that changes the photophysical properties were performed and for these compounds, structure: photophysical properties were discussed.
Gazi Üniversitesi Orman Fakültesi dergisi, Apr 3, 2021
Aim of Study: It was aimed to determine the chemical composition, antioxidant and antibacterial a... more Aim of Study: It was aimed to determine the chemical composition, antioxidant and antibacterial activity of the Thymus praecox which distributed in the Kastamonu region. Material and methods: Spectroscopic and chromotographic analysis were applied in the determination of the chemical composition. Thyme extracts were prepared using five different solvents. In Thymus praecox, the presence of flavonoids using HPLC and the chemical content of essential oil using GC-MS were investigated. The analyses of the mineral were determined in leaf and stem of thyme by ICP-OES. Antioxidant capacity was determined using two methods such as DPPH free radical scavenging and H2O2 scavenging. Antibacterial activity on ten bacteria, Gram (+) and Gram (-) was tested using the disc diffusion method. Main results: Experimental results showed that thyme extracts have antibacterial activities against some bacteria. As a result, it was found that the most affected bacteria was S. aureus. Inhibition zone diameter was determined to be between 8-12 mm. The effect of solvent on antibacterial activity, antioxidant capacity, total phenolic and total flavonoid amounts were observed. Highlights: These results showed that T. praecox has the potential to be used as a natural antimicrobial and antioxidant agent, and can be used as a natural supportive treatment.
After the synthesis of the new benzimidazole derivative 1,3,4-thiadiazole compound, a series of a... more After the synthesis of the new benzimidazole derivative 1,3,4-thiadiazole compound, a series of azo dyes from the reaction of this compound with various coupling components and a series of schiff bases were synthesized from the reaction with various aldehydes. The structures of the obtained compounds are characterized and interpreted with UV, FT-IR and 1 H-NMR. The fluorescence properties of the compounds were also investigated, and the absorption and emission properties of schiff base and azo dyes obtained from the same derivative were examined. As a result, it was observed that schiff bases obtained from benzimidazole derivative 1,3,4thiadiazole compound had longer wavelength absorption-emission compared to azo dyes obtained from the same compound. Experimental data were supported by density functional theory (DFT) calculations. The ground state geometries, spectroscopic properties, FMO energies and related chemical reactivity parameters of the compounds were calculated using the B3LYP hybrid density functional combined with 6-311++G(2d,2p) basis set. At the same theory level, QTAIM and IRI analyzes were also performed and the data were used to determine the properties of tautomeric structures. The electronic properties of the compounds were studied and a detailed analysis was performed by comparing them with experimental data.
In the study, the active drugs molecules used in the treatment of convulsive seizures occurring i... more In the study, the active drugs molecules used in the treatment of convulsive seizures occurring in epilepsy disease were used.
Hitite journal of science and engineering, May 10, 2023
W hen the studies are examined, it has been seen that heterocyclic molecules are generally used f... more W hen the studies are examined, it has been seen that heterocyclic molecules are generally used for the biological activity tests of the compounds. Thiadiazole rings containing two nitrogens and one sulphur atom are very popular compounds for such studies. In particular, the 1,3,4-thiadiazole isomers are the prominent derivatives in the thiadiazole class in terms of their pharmacological properties. 1,3,4-thiadiazole molecules and their derivatives possess a wide range of pharmacological activities like anticancer/antitumor (1,2), anticonvulsant (3,4), antidiabetic (5,6), anti-inflammatory (7,8), antidepressant (9), antihypertensive (10), antiviral (11,12), antileishmanial (13,14), antimicrobial (15,16) and many more. Among these studies, the most common pharmacological feature is antimicrobial studies. Because of the over/ misuse of antibiotics, antibiotic resistance caused by microorganisms is now recognized as a serious global threat. As a precaution against this situation, studies are being carried out for developing novel agents that
HAL (Le Centre pour la Communication Scientifique Directe), 2016
Optical Materials, Apr 1, 2023
Gazi Üniversitesi Orman Fakültesi dergisi, Sep 15, 2018
Aim of study: The objectives in this study were to determine the chemical composition and antimic... more Aim of study: The objectives in this study were to determine the chemical composition and antimicrobial activity of the essential oils from nutmeg (Myristica fragrans) and cardamom (Elettaria cardamomum). Material and Methods: The essential oil was obtained from nutmeg and cardamom seeds through hydrodistillation method. The chemical composition of nutmeg and cardamom essential oil was analyzed by GC-MS. The antimicrobial activity of essential oil was investigated against
Journal of Molecular Structure, Dec 1, 2018
Hetero-crown ethers (ligands I-IV) containing 1,3,4-thiadiazole-2,5-dithiol (bismuthiol) were syn... more Hetero-crown ethers (ligands I-IV) containing 1,3,4-thiadiazole-2,5-dithiol (bismuthiol) were synthesized and fully characterized. The ligands were prepared by a nucleophilic substitution (S N 2) reaction of the appropriate ethylene glycol dihalide derivatives with 1,3,4-thiadiazole-2,5-dithiol dipotassium salt under highly diluted conditions, and subsequent ring closure. Complexation constants and selectivity factors for these heterocyclic ligands in dichloromethane or chloroform were determined by ion-pair extraction from an aqueous solution containing
Indian Journal of Pharmaceutical Education and Research, Jul 25, 2017
Essential oils were obtained from Coriandrum sativum and Alpinia officinarum through steam distil... more Essential oils were obtained from Coriandrum sativum and Alpinia officinarum through steam distillation method in this study. Antimicrobial activities of the obtained essential oils were investigated by using minimum inhibitory concentration (MIC) test by against 18 different species microorganisms. It was found that the C. sativum had strong antimicrobial activities against the 14 tested microorganism and A. officinarum oils showed strong antimicrobial activity against the 7 tested microorganisms. Furthermore, the contents of the essential oils were determined with GC-MS analyses. The most abundant compounds of essential oils of A. officinarum and C. sativum were determined as 28.4% eucalyptol and 69.4% linalool. As a result, it can be easily said that the essential oils of C. sativum and A. officinarum can be used as antimicrobial protector in related fields.
New Journal of Chemistry, 2021
A novel phenanthroimidazole derivative with p-type conductivity was prepared and fabricated as a ... more A novel phenanthroimidazole derivative with p-type conductivity was prepared and fabricated as a heterostructure, exhibiting a negative differential resistance and photodiode properties.
Journal of Molecular Structure, Apr 1, 2017
In this study, 4,7-dihydrotetrazolo[1, 5-a]pyrimidine derivatives (1-5) were prepared via Multico... more In this study, 4,7-dihydrotetrazolo[1, 5-a]pyrimidine derivatives (1-5) were prepared via Multicomponent Cyclocondensation Reactions (MCRs). All structures were determined by using FT-IR, 1 H/ 13 C NMR and elemental analyses. The compounds were investigated as corrosion inhibitors using density functional theory (DFT) at the level of B3LYP/6-31G (d, p). According to the calculations, compound 1 appears to be a good inhibitor for corrosion. In addition, the electrochemical properties of the novel systems were investigated by CV.
Journal of Heterocyclic Chemistry, Jan 22, 2019
Journal of Heterocyclic Chemistry, Sep 14, 2017
Gazi Üniversitesi Orman Fakültesi dergisi, Dec 28, 2018
Aim of study: The aim of this study is to put forward the antimicrobial activity of cold pressed ... more Aim of study: The aim of this study is to put forward the antimicrobial activity of cold pressed oils obtained from seeds of nettle (Urtica dioica), radish (Raphanus sativus) and pomegranate (Punica granatum). Material and Methods: Oils of these seeds were analysed for their antibacterial and antifungal activities by the disk diffusion and MIC tests against fifteen microorganisms,
El-cezeri, Apr 17, 2023
This study includes the structure-activity relationship of active molecules that are commonly use... more This study includes the structure-activity relationship of active molecules that are commonly used in the treatment of convulsive seizures in epileptic diseases. Well-known epileptic active molecules studied are:
Journal of Molecular Structure, Mar 1, 2020
A combined experimental and computational study of a ruthenium(II) polypyridyl complex: Synthesis... more A combined experimental and computational study of a ruthenium(II) polypyridyl complex: Synthesis, characterization, electronic structures and spectral properties,
Journal of characterization, 2023
Thanks to their chemical, thermal, photophysical, and photochemical properties, phenanthroimidazo... more Thanks to their chemical, thermal, photophysical, and photochemical properties, phenanthroimidazole derivative compounds attract attention in optoelectronic device technology, especially in OLEDs. For this reason, phenanthroimidazole derivatives are the most promising compounds for these applications in the future. In this study, the-diCl bearing phenanthroimidazole compound was synthesized, characterized, and investigated in detail the photophysical and aggregation properties. Spectroscopic studies for its characterization used 1 H-NMR, ATR-IR, and detailed LCMS-MS (mass and product ion scan). The absorption and emission spectra of diCl-PHN have been recorded with solvents of different polarities at room temperature. diCl-PHN exhibit high fluorescence quantum yield in DMSO with 0.78. CIE chromaticity diagram results of diCl-PHN were obtained and displayed good intensity. Additionally, aggregation properties were recorded at seven different water concentrations (water/DMSO %). With the results obtained from the study, it was concluded that this phenanthroimidazole derivative compound is a suitable molecule for fluorescent applications.