Awatif Jamal | King AbdulAziz University (KAU) Jeddah, Saudi Arabia (original) (raw)

Papers by Awatif Jamal

Additional file 5: Figure S3. CSCs markers expression in situ. A) Images for immunofluorescence c... more Additional file 5: Figure S3. CSCs markers expression in situ. A) Images for immunofluorescence co-staining of stem cell markers CD133+Sox2+ (Green, Red) or Nestin+Ki67+ (Green, Red) and AGR2+ BMI1+ (Red, Green) in low grade (Jed62_MN) and high grade (Jed45_MN) tumors. B) Mean percentages of co-positive cells. Error bars represent count errors between three independent regions within each tissue. All images were taken at 20Ă .

Saudi medical journal, 2003

Cervical carcinoma is an important women's health problem in the Western countries. There are... more Cervical carcinoma is an important women's health problem in the Western countries. There are only few published data on this disease in the Kingdom of Saudi Arabia (KSA). The aim of this study is to evaluate the abnormal cytological entities detected by cervical Pap smear in Western region of KSA and to discuss the importance of Pap smears screening programs. Retrospective review of all the cervical smears present at the King Abdul-Aziz University Hospital, Jeddah, KSA from 1984 to 2000. The reports of 22089 smears were retrieved from the file of the pathology department. There were 368 (1.66%) abnormal Pap smears out of 22089 smears. Out of these 368 abnormal Pap smears there were 62 (16.8%, mean age 37 year) cervical intraepithelial neoplasia grade 1, 45 (12.2%, mean age 38.5) cervical intraepithelial neoplasia grade 2, 27 (7.3%, mean age 40.5) cervical intraepithelial neoplasia grade 3, 22 (6%, mean age 38.5) positive for malignant cells, 36 (9.8%, mean age 40.5) atypical en...

BACKGROUND: Primary intracranial germ cell tumors are rare (ICGCTs) and usually localized in the ... more BACKGROUND: Primary intracranial germ cell tumors are rare (ICGCTs) and usually localized in the pineal and suprasellar regions of the brain. They are divided into histologic types: Germinoma, teratoma choriocarcinoma, embryonal carcinoma, yolk sac tumor, and malignant mixed germ cell tumors (MMGCTs). Neuroimaging evaluation is useful to distinguish between the types of ICGCTs. Germinoma is highly sensitive to radiotherapy or/and chemotherapy, and is potentially curable without surgery. MMGCTs are treated with the combination of chemotherapy and radiation, with a poorer prognosis. ICGCTs warrant correct pre-operative diagnosis in order to decide on appropriate management.AIM: To report the clinicopathological and immunohistochemical findings in three cases of primary intracranial germ-cell tumor.MATERIALS AND METHODS: Three cases of intracranial germ cell tumors inclusive of both genders and all brain regions were retrieved from the archives of the Anatomical Pathology Department at King Abdul Aziz University Hospital, Jeddah between the years, 1995-2011, through a computerized search.RESULTS: Based on histological examination, they were respectively diagnosed as MMGCTs (two cases) and germinoma. Clinical, radiological, pathological characteristics and immunohistochemical profile of the three ICGCTs are presented along with the review of recent literature.CONCLUSION: ICGCTs are rare tumors affecting males more than females, and at the end of three years follow-up in the present study, treatment morbidity appears to be low with no recurrence observed among surviving patients, indicating that suprasellar and basal ganglia ICGCTs may have a favorable prognosis regardless of histological type. Pineal MMGCTs may have an aggressive course.

Asian Pacific journal of cancer prevention : APJCP, 2015

Many developing countries are lagging behind in reporting epidemiological data for individual cen... more Many developing countries are lagging behind in reporting epidemiological data for individual central nervous system (CNS) tumors. This paper aimed to elicit patterns for the epidemiology of individual World Health Organization (WHO) classified CNS tumors in countries registered by WHO as "developing". Cyber search was carried out through 66 cancer networks/registries and 181 PubMed published papers that reported counts of CNS tumors for the period of 2009-2012. The relationship between the natural log of incidence Age Standardized Rate (ASR) reported by Globocan and Latitude/ Longitude was investigated. Registries for 21 countries displayed information related to CNS tumors. In contrast tends for classified CNS tumor cases were identified for 38 countries via 181 PubMed publications. Extracted data showed a majority of unclassified reported cases [PubMed (38 countries, 45.7%), registries (21 countries, 96.1%)]. For classified tumors, astrocytic tumors were the most freque...

Additional file 5: Figure S3. CSCs markers expression in situ. A) Images for immunofluorescence c... more Additional file 5: Figure S3. CSCs markers expression in situ. A) Images for immunofluorescence co-staining of stem cell markers CD133+Sox2+ (Green, Red) or Nestin+Ki67+ (Green, Red) and AGR2+ BMI1+ (Red, Green) in low grade (Jed62_MN) and high grade (Jed45_MN) tumors. B) Mean percentages of co-positive cells. Error bars represent count errors between three independent regions within each tissue. All images were taken at 20Ă .

Saudi medical journal, 2003

Cervical carcinoma is an important women's health problem in the Western countries. There are... more Cervical carcinoma is an important women's health problem in the Western countries. There are only few published data on this disease in the Kingdom of Saudi Arabia (KSA). The aim of this study is to evaluate the abnormal cytological entities detected by cervical Pap smear in Western region of KSA and to discuss the importance of Pap smears screening programs. Retrospective review of all the cervical smears present at the King Abdul-Aziz University Hospital, Jeddah, KSA from 1984 to 2000. The reports of 22089 smears were retrieved from the file of the pathology department. There were 368 (1.66%) abnormal Pap smears out of 22089 smears. Out of these 368 abnormal Pap smears there were 62 (16.8%, mean age 37 year) cervical intraepithelial neoplasia grade 1, 45 (12.2%, mean age 38.5) cervical intraepithelial neoplasia grade 2, 27 (7.3%, mean age 40.5) cervical intraepithelial neoplasia grade 3, 22 (6%, mean age 38.5) positive for malignant cells, 36 (9.8%, mean age 40.5) atypical en...

BACKGROUND: Primary intracranial germ cell tumors are rare (ICGCTs) and usually localized in the ... more BACKGROUND: Primary intracranial germ cell tumors are rare (ICGCTs) and usually localized in the pineal and suprasellar regions of the brain. They are divided into histologic types: Germinoma, teratoma choriocarcinoma, embryonal carcinoma, yolk sac tumor, and malignant mixed germ cell tumors (MMGCTs). Neuroimaging evaluation is useful to distinguish between the types of ICGCTs. Germinoma is highly sensitive to radiotherapy or/and chemotherapy, and is potentially curable without surgery. MMGCTs are treated with the combination of chemotherapy and radiation, with a poorer prognosis. ICGCTs warrant correct pre-operative diagnosis in order to decide on appropriate management.AIM: To report the clinicopathological and immunohistochemical findings in three cases of primary intracranial germ-cell tumor.MATERIALS AND METHODS: Three cases of intracranial germ cell tumors inclusive of both genders and all brain regions were retrieved from the archives of the Anatomical Pathology Department at King Abdul Aziz University Hospital, Jeddah between the years, 1995-2011, through a computerized search.RESULTS: Based on histological examination, they were respectively diagnosed as MMGCTs (two cases) and germinoma. Clinical, radiological, pathological characteristics and immunohistochemical profile of the three ICGCTs are presented along with the review of recent literature.CONCLUSION: ICGCTs are rare tumors affecting males more than females, and at the end of three years follow-up in the present study, treatment morbidity appears to be low with no recurrence observed among surviving patients, indicating that suprasellar and basal ganglia ICGCTs may have a favorable prognosis regardless of histological type. Pineal MMGCTs may have an aggressive course.

Asian Pacific journal of cancer prevention : APJCP, 2015

Many developing countries are lagging behind in reporting epidemiological data for individual cen... more Many developing countries are lagging behind in reporting epidemiological data for individual central nervous system (CNS) tumors. This paper aimed to elicit patterns for the epidemiology of individual World Health Organization (WHO) classified CNS tumors in countries registered by WHO as "developing". Cyber search was carried out through 66 cancer networks/registries and 181 PubMed published papers that reported counts of CNS tumors for the period of 2009-2012. The relationship between the natural log of incidence Age Standardized Rate (ASR) reported by Globocan and Latitude/ Longitude was investigated. Registries for 21 countries displayed information related to CNS tumors. In contrast tends for classified CNS tumor cases were identified for 38 countries via 181 PubMed publications. Extracted data showed a majority of unclassified reported cases [PubMed (38 countries, 45.7%), registries (21 countries, 96.1%)]. For classified tumors, astrocytic tumors were the most freque...