Naila Iftikhar | Keele University (original) (raw)
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A patient with tuberculosis of the vulva is reported. A 50 years old unmarried female had complai... more A patient with tuberculosis of the vulva is reported. A 50 years old unmarried female had complaint of persistent vaginal discharge for 10 years. On examination her vulva was hypertrophied and there were papillary growths on clitoral and rectal region. Biopsy showed chronic caseating granulomatous inflammation suggestive of Tuberculosis. The lesions healed completely after giving antituberculous chemotherapy for 6 months.
To evaluate the effects of clomiphene citrate alone versus combined metformin and clomiphene citr... more To evaluate the effects of clomiphene citrate alone versus combined metformin and clomiphene citrate in patients of polycystic ovarian syndrome with anovulatory infertility in increasing ovulation and pregnancy rate. STUDY DESIGN: A Randomized controlled study. PLACE AND DURATION: The study was done at the infertility clinic of Gynaecology and Obstetrics dept of KRL hospital Islamabad for one year from 16th November, 2009 till 15th November, 2010. METHODOLOGY: 74 diagnosed patients of PCOS with anovulatory infertility were included in the study. Simple random sampling was done and 37 patients of group A were given clomiphene citrate from 50-150 mg on 2nd-6th day of menstrual cycle, for 6 cycles. The patients of group B were given Metformin 1.5 gms daily for 6 months alongwith clomiphene citrate 50-150 mg on 2nd-6th day of menstrual period, maximum 6 cycles. Ovulation was monitored by transvaginal sonography and serum progesterone level measurement which was done on 21st day of the cycle. Pregnancy was confirmed by serum B-hCG. RESULTS: CONCLUSION: The results proved that metformin along with clomiphene citrate significantly improves ovulation and pregnancy rate in patients of PCOS with anovulatory infertility and the combination of both drugs produced far better results than clomiphene citrate alone.
The Professional Medical Journal
Objective: The women residing in a developing country have 200 times greater risk of suffering fr... more Objective: The women residing in a developing country have 200 times greater risk of suffering from pregnancy and childbirthrelated mortality compared with the women of a developed country. To investigate relevant causes and the determinants of maternal mortalitythrough conducting scientific clinical studies. Methodologies: We conducted a prospective study of maternal deaths in the obstetrics andgynaecology unit of RGH for one year. Period: January 2007 to December 2007. We investigated the socio-demographic variables - includingage, parity, socio-economic status and literacy - along with the social behavior towards the antenatal. We designed standardized data collectingforms to collect data from the confidential hospital notes of the patients. The collected medical data of the patients proved useful in analyzingthe underlying causes and the risk factors behind direct and indirect maternal mortalities. Results: In our unit, we have recorded 28 maternaldeaths during the study period....
A patient with tuberculosis of the vulva is reported. A 50 years old unmarried female had complai... more A patient with tuberculosis of the vulva is reported. A 50 years old unmarried female had complaint of persistent vaginal discharge for 10 years. On examination her vulva was hypertrophied and there were papillary growths on clitoral and rectal region. Biopsy showed chronic caseating granulomatous inflammation suggestive of Tuberculosis. The lesions healed completely after giving antituberculous chemotherapy for 6 months.
To evaluate the effects of clomiphene citrate alone versus combined metformin and clomiphene citr... more To evaluate the effects of clomiphene citrate alone versus combined metformin and clomiphene citrate in patients of polycystic ovarian syndrome with anovulatory infertility in increasing ovulation and pregnancy rate. STUDY DESIGN: A Randomized controlled study. PLACE AND DURATION: The study was done at the infertility clinic of Gynaecology and Obstetrics dept of KRL hospital Islamabad for one year from 16th November, 2009 till 15th November, 2010. METHODOLOGY: 74 diagnosed patients of PCOS with anovulatory infertility were included in the study. Simple random sampling was done and 37 patients of group A were given clomiphene citrate from 50-150 mg on 2nd-6th day of menstrual cycle, for 6 cycles. The patients of group B were given Metformin 1.5 gms daily for 6 months alongwith clomiphene citrate 50-150 mg on 2nd-6th day of menstrual period, maximum 6 cycles. Ovulation was monitored by transvaginal sonography and serum progesterone level measurement which was done on 21st day of the cycle. Pregnancy was confirmed by serum B-hCG. RESULTS: CONCLUSION: The results proved that metformin along with clomiphene citrate significantly improves ovulation and pregnancy rate in patients of PCOS with anovulatory infertility and the combination of both drugs produced far better results than clomiphene citrate alone.
The Professional Medical Journal
Objective: The women residing in a developing country have 200 times greater risk of suffering fr... more Objective: The women residing in a developing country have 200 times greater risk of suffering from pregnancy and childbirthrelated mortality compared with the women of a developed country. To investigate relevant causes and the determinants of maternal mortalitythrough conducting scientific clinical studies. Methodologies: We conducted a prospective study of maternal deaths in the obstetrics andgynaecology unit of RGH for one year. Period: January 2007 to December 2007. We investigated the socio-demographic variables - includingage, parity, socio-economic status and literacy - along with the social behavior towards the antenatal. We designed standardized data collectingforms to collect data from the confidential hospital notes of the patients. The collected medical data of the patients proved useful in analyzingthe underlying causes and the risk factors behind direct and indirect maternal mortalities. Results: In our unit, we have recorded 28 maternaldeaths during the study period....