Masroor Sharfi | King Faisal Specialist Hospital and Research Centre (original) (raw)
Papers by Masroor Sharfi
Pakistan Journal of Health Sciences
Atrial Fibrillation (AF) is one of the common arrhythmias after coronary artery bypass grafting (... more Atrial Fibrillation (AF) is one of the common arrhythmias after coronary artery bypass grafting (CABG) mostly occurs within 2 to 4 days. The advanced age is one of the important risk factors. Objective: To determine the frequency of Postoperative Atrial Fibrillation (POAF) in patients age between 30-65 years who underwent elective CABG Surgery. Methods: One hundred and thirty-seven Adult patients of either sex between age of 30 to 65 years with three vessel coronary artery disease underwent elective CABG surgery were included in our study. It was descriptive cross-sectional study, conducted at Tabba Heart Institute, Karachi, from December 2021 to June 2022. Postoperatively daily EKG was performed for the evidence of POAF. Results: One hundred and thirty-seven patients, between age group of 30-65 years among them 115 (84%) were male & 22 (16%) were females with mean age of patients 55.91years were included in our study. Post-Operative Atrial Fibrillation (POAF) was observed in 12.4%,...
Pediatric Cardiology, Aug 6, 2004
International journal of advanced research, Jun 30, 2021
<jats:p>Introduction:Cardiac troponin-I being a sensitive marker of myocardial damage needs... more <jats:p>Introduction:Cardiac troponin-I being a sensitive marker of myocardial damage needs to be analyzed in children undergoing cardiopulmonary by-pass surgery, as perioperative myocardial damage may be a significant factor of postoperative cardiac performance. The present study aims to test the prognostic value of Cardiac troponin-I concerning the early postoperative course after pediatric cardiac surgery. Methods:Cardiac troponin – I levels were measured and correlated with intra and postoperative parameters of thirty-three children undergoing open-heart surgery. The cutoff point for the definition of a high and a low-risk group of Cardiac troponin-I values was set at 25 ng/ml. Results:Overall, cTnI peak value was higher than 25 ng/ml in 21 patients among these,4 died, and two of them were reported with the value of >100 ng/ml. 38.7% of the patients were complicated by different types of arrhythmias. Junctional ectopic tachycardia was the most common type of arrhythmia,while heart block complication was found only in one case, which was temporarily treated by pacing for less than 24 hours. The results showed significant correlation of troponin I values with dobutamine dose mg/kg (p-value=0.043), dobutamine duration (p-value=0.020), creatinine (p-value= 0.002), and internalcare unit stay (p-value= 0.003). Conclusion: The present study confirms that troponin I is specific and sensitive marker of myocardial injury after pediatric cardiac surgery.</jats:p>
Journal of Biosciences and Medicines, 2021
This review aims to sum up the improvements witnessed in the field of interventional cardiology d... more This review aims to sum up the improvements witnessed in the field of interventional cardiology during recent times. The last decade has witnessed significant technical advances in the field of radiological imaging and also in interventional cardiology which has helped to offer more non-invasive solutions for the management of congenital heart defects. This has resulted from the use of advanced 3-dimensional fusion imaging instead of conventional 2-dimensional angiography, applying interactive real-time enhancement and using computed tomography and Magnetic Resonance Imaging for interventional procedures. Similarly the introduction of next generation devices, have not only improved the final outcome of the procedure but also has helped in reducing the challenges that were faced before and with the initial generation of devices. These advances have helped not only in reducing the radiation exposure, the use of contrast medium dose but also have resulted in improved early survival. The field of neonatal cardiology has advanced at an unprecedented pace. The transcatheter closure of patent ductus arteriosus has evolved over time and now it has been made possible at much lower body weight. Similarly, early use of stents for aortic coarctation has been found effective in some patients, especially when surgical intervention had been denied. The application of the hybrid approach for the management of complex congenital heart defects has also been effectively applied. More recently transcatheter placement of the pulmonary valve has been introduced for severely stenotic and/or regurgitant pulmonary valve in adolescents and adults. It is anticipated that in near future, this procedure would be available for relatively younger patients. In conclusion: last 2 decades have improvised pediatric in
Pakistan Journal of Medical and Health Sciences, Jan 31, 2023
Pakistan Journal of Medical and Health Sciences
Background: The most common issue with transradial cardiac catheterization is radial artery vasos... more Background: The most common issue with transradial cardiac catheterization is radial artery vasospasm. The patient experiences pain and discomfort as a result, the procedure is prolonged, and the interventionist may even be unable to continue. Aim: The aim of the study is to determine the effectiveness of Verapamil, a calcium channel blocker and nitrate, when used together to prevent radial artery spasm during coronary angiographies. Methods: This case control study was held in the Cardiology department of Qazi Hussain Ahmed Medical Complex, Nowshera and Peoples University of Medical and Health Sciences for Women PUMHSW (SBA) Nawabshah for six-months duration from July 2021 to December 2021 including 120 cardiac patients undergoing coronary angiography. The patients were selected by non-probability sampling technique. Patients who were enrolled in the study provided written informed consent. Two groups of patients—control (60) and experimental—were formed (60). Heparin/nitrate was a...
Journal of The Saudi Heart Association, 2019
Transcatheter closure of secundum atrial septal defect is routinely performed under general anest... more Transcatheter closure of secundum atrial septal defect is routinely performed under general anesthesia and transesophageal echocardiography guidance. If patients have good echo windows, the procedure could be performed under transthoracic echo guidance. To evaluate safety and efficacy of the intervention using fluoroscopy and echo guidance. In a case control study design, 180 patients underwent atrial septal defect closure between January 2010 and December 2016. In 32 patients, the intervention was performed under fluoroscopy and transthoracic echo guidance. Our study group consisted of 22 out of 32 patients (&amp;amp;amp;lt;13 years old). For the other 10 patients, we could not find a matching pair. The data of the study group were compared with an age, weight, and height matched group (controls), who underwent the procedure under transesophageal echocardiography guidance. The diameter of the atrial septal defect, septal length, and most of the rims were comparable. The superior rim and inferior rims were longer in the study group. The devices chosen for the cases were larger than the control group. Procedure time and fluoroscopy times were shorter in the study group. Success rate was comparable. On follow-up, both groups had almost no or minimal incidence of residual shunt. We conclude that transcatheter closure of atrial septal defect under fluoroscopy and transthoracic echo guidance is safe and successful in selected patients who have single central atrial septal defect with adequate septal lengths and adequate septal rims, with high incidence of complete occlusion rate.
Pakistan Journal of Medical and Health Sciences, Apr 14, 2023
Pakistan Journal of Medical and Health Sciences, Jan 31, 2023
Pakistan Journal of Medical and Health Sciences
Background: Chest pain is the communal complaint among pediatric age groups. Chest pain due to he... more Background: Chest pain is the communal complaint among pediatric age groups. Chest pain due to heart disease is rare in children and adolescents, with an incidence of less than 6%. History and physical examination may be sufficient to identify the most important etiologies. Aim: The aim of the study is to review various causes of chest pain in young patients admitted to a pediatric cardiology clinic. Method: We retrospectively analyzed the clinical data of our patients visited to emergency or outpatient clinics in our hospital with chest pain from March 2022 to October 2022. A total of 56 patients (36 females and 20 males), aged 5-15 years were included in this study. Follow-up of the patients was carried out by calling all relatives of the patient and asking about the child's condition and chest pain. Clinical history and physical examination were performed. Results: A total of 56 patients between the ages of 5 and 15 were enrolled in the study, with a mean age of 11.78 ± 2.95 ...
Pakistan Journal of Medical and Health Sciences
Background: Soft tissue abscesses is one of the most commonly observed complication in children. ... more Background: Soft tissue abscesses is one of the most commonly observed complication in children. This infection may impart the longer stay at hospital and also increase the cost of medical care. Objective: The study was carried out to find the pattern of organisms and the sensitivity of drugs from the pus produced in soft tissue abscesses among patients. Study design: It is cross-sectional study conducted from January 2020 to November 2022. Material and Methods: The study was conducted at the pediatric department of the Div. HQ teaching hospital Mirpur, Azad Jammu and Kashmir. The study was carried out on 160 patients having at least one abscess on their body. The study also collected information about the predisposing factor that could have led to abscess formation. The site of distribution of the abscess was also analyzed. The abundance of microorganisms that were isolated from the samples of abscesses was also studied. Results: it was found that in most of the patients (45.5%) th...
Pakistan BioMedical Journal
Exercise echocardiography has become a significant tool of non-invasive valuation of coronary art... more Exercise echocardiography has become a significant tool of non-invasive valuation of coronary artery disease (CAD). The Exercise echocardiography and dobutamine stress echocardiography are widely applied methods with different clinical procedures and indications. Objective: To determine the exercise echocardiography and dobutamine stress echocardiography in the assessment of suspected or known coronary artery disease. Methods: 260 consecutive patients endured Stress Echocardiography in the Cardiology department of NICVD Karachi for one-year duration from January 2021 to December 2021. The treadmill was used for Exercise echocardiography applying the Bruce protocol. The standard method was applied for dobutamine stress echocardiography. The Stress Echocardiography was taken as positive on the basis of the appearance of worsening or new wall motion abnormalities. Results: Exercise echocardiography performed by 160 patients and DSE in 100 subjects with mean age of 47.21 and 53.10 years...
International Journal of Advanced Research, Jun 30, 2021
<jats:p>Introduction:Cardiac troponin-I being a sensitive marker of myocardial damage needs... more <jats:p>Introduction:Cardiac troponin-I being a sensitive marker of myocardial damage needs to be analyzed in children undergoing cardiopulmonary by-pass surgery, as perioperative myocardial damage may be a significant factor of postoperative cardiac performance. The present study aims to test the prognostic value of Cardiac troponin-I concerning the early postoperative course after pediatric cardiac surgery. Methods:Cardiac troponin – I levels were measured and correlated with intra and postoperative parameters of thirty-three children undergoing open-heart surgery. The cutoff point for the definition of a high and a low-risk group of Cardiac troponin-I values was set at 25 ng/ml. Results:Overall, cTnI peak value was higher than 25 ng/ml in 21 patients among these,4 died, and two of them were reported with the value of >100 ng/ml. 38.7% of the patients were complicated by different types of arrhythmias. Junctional ectopic tachycardia was the most common type of arrhythmia,while heart block complication was found only in one case, which was temporarily treated by pacing for less than 24 hours. The results showed significant correlation of troponin I values with dobutamine dose mg/kg (p-value=0.043), dobutamine duration (p-value=0.020), creatinine (p-value= 0.002), and internalcare unit stay (p-value= 0.003). Conclusion: The present study confirms that troponin I is specific and sensitive marker of myocardial injury after pediatric cardiac surgery.</jats:p>
Asian Journal of Research in Cardiovascular Diseases, Jun 19, 2021
Asian Journal of Research in Cardiovascular Diseases, Sep 28, 2021
Journal of the Saudi Heart Association
Pakistan Journal of Medical and Health Sciences
COPD has been recognized as a component of the systemic inflammatory syndrome. A commonly used in... more COPD has been recognized as a component of the systemic inflammatory syndrome. A commonly used indicator of the severity and progression of the disease in COPD is expiratory volume per second (FEV1). However, it is weakly associated with symptoms and administration difficulties in elderly patients. Therefore, there is a need for other markers that are better and easy to apply to sick and elderly patients. Plasma fibrinogen can be used as a marker of disease severity. Aim: To estimate the plasma fibrinogen level in patients with COPD and Relationship of levels of plasma fibrinogen with the severity of chronic obstructive pulmonary disease using the BODE classification and GOLD staging. Place and Duration: In the Medicine Unit-II of Jinnah Hospital Lahore for one-year duration from August 2020 to August 2021. Methods: In this cross-sectional study, 110 COPD patients were assessed by measuring plasma fibrinogen correlated with disease severity using the GOLD scale, BODE index and the 6...
This review aims to sum up the improvements witnessed in the field of interventional cardiology d... more This review aims to sum up the improvements witnessed in the field of interventional cardiology during recent times. The last decade has witnessed significant technical advances in the field of radiological imaging and also in interventional cardiology which has helped to offer more non-invasive solutions for the management of congenital heart defects. This has resulted from the use of advanced 3-dimensional fusion imaging instead of conventional 2-dimensional angiography, applying interactive real-time enhancement and using computed tomography and Magnetic Resonance Imaging for interventional procedures. Similarly the introduction of next generation devices, have not only improved the final outcome of the procedure but also has helped in reducing the challenges that were faced before and with the initial generation of devices. These advances have helped not only in reducing the radiation exposure, the use of contrast medium dose but also have resulted in improved early survival. Th...
Here we report an extremely rare case of congenitally corrected transposition of great arteries (... more Here we report an extremely rare case of congenitally corrected transposition of great arteries (CCTGA) associated with Interrupted aortic arch (IAA) type A and ventricular septal defect (VSD) in a preterm baby. Antenatally diagnosed as large VSD and severe Coarctation of aorta. Echocardiogram done revealed that left ventricle with the mitral valve lay on the right side in continuation with the venous right atrium and was connected to the pulmonary artery. The right ventricle lay on the left in continuation with the arterial left atrium and was connected to the aorta. Smallish transverse arch with Interruption of aorta below the left subclavian artery. Large VSD with bidirectional shunt. Small PDA with restrictive right to left flow. As far we know, only one similar case was reported earlier by Cottrell, at el. (4). At that time the initial diagnosis was done by cardiac angiography as 2D color echocardiography was not available at their center, after one year they were able to use e...
Pakistan Journal of Health Sciences
Atrial Fibrillation (AF) is one of the common arrhythmias after coronary artery bypass grafting (... more Atrial Fibrillation (AF) is one of the common arrhythmias after coronary artery bypass grafting (CABG) mostly occurs within 2 to 4 days. The advanced age is one of the important risk factors. Objective: To determine the frequency of Postoperative Atrial Fibrillation (POAF) in patients age between 30-65 years who underwent elective CABG Surgery. Methods: One hundred and thirty-seven Adult patients of either sex between age of 30 to 65 years with three vessel coronary artery disease underwent elective CABG surgery were included in our study. It was descriptive cross-sectional study, conducted at Tabba Heart Institute, Karachi, from December 2021 to June 2022. Postoperatively daily EKG was performed for the evidence of POAF. Results: One hundred and thirty-seven patients, between age group of 30-65 years among them 115 (84%) were male & 22 (16%) were females with mean age of patients 55.91years were included in our study. Post-Operative Atrial Fibrillation (POAF) was observed in 12.4%,...
Pediatric Cardiology, Aug 6, 2004
International journal of advanced research, Jun 30, 2021
<jats:p>Introduction:Cardiac troponin-I being a sensitive marker of myocardial damage needs... more <jats:p>Introduction:Cardiac troponin-I being a sensitive marker of myocardial damage needs to be analyzed in children undergoing cardiopulmonary by-pass surgery, as perioperative myocardial damage may be a significant factor of postoperative cardiac performance. The present study aims to test the prognostic value of Cardiac troponin-I concerning the early postoperative course after pediatric cardiac surgery. Methods:Cardiac troponin – I levels were measured and correlated with intra and postoperative parameters of thirty-three children undergoing open-heart surgery. The cutoff point for the definition of a high and a low-risk group of Cardiac troponin-I values was set at 25 ng/ml. Results:Overall, cTnI peak value was higher than 25 ng/ml in 21 patients among these,4 died, and two of them were reported with the value of >100 ng/ml. 38.7% of the patients were complicated by different types of arrhythmias. Junctional ectopic tachycardia was the most common type of arrhythmia,while heart block complication was found only in one case, which was temporarily treated by pacing for less than 24 hours. The results showed significant correlation of troponin I values with dobutamine dose mg/kg (p-value=0.043), dobutamine duration (p-value=0.020), creatinine (p-value= 0.002), and internalcare unit stay (p-value= 0.003). Conclusion: The present study confirms that troponin I is specific and sensitive marker of myocardial injury after pediatric cardiac surgery.</jats:p>
Journal of Biosciences and Medicines, 2021
This review aims to sum up the improvements witnessed in the field of interventional cardiology d... more This review aims to sum up the improvements witnessed in the field of interventional cardiology during recent times. The last decade has witnessed significant technical advances in the field of radiological imaging and also in interventional cardiology which has helped to offer more non-invasive solutions for the management of congenital heart defects. This has resulted from the use of advanced 3-dimensional fusion imaging instead of conventional 2-dimensional angiography, applying interactive real-time enhancement and using computed tomography and Magnetic Resonance Imaging for interventional procedures. Similarly the introduction of next generation devices, have not only improved the final outcome of the procedure but also has helped in reducing the challenges that were faced before and with the initial generation of devices. These advances have helped not only in reducing the radiation exposure, the use of contrast medium dose but also have resulted in improved early survival. The field of neonatal cardiology has advanced at an unprecedented pace. The transcatheter closure of patent ductus arteriosus has evolved over time and now it has been made possible at much lower body weight. Similarly, early use of stents for aortic coarctation has been found effective in some patients, especially when surgical intervention had been denied. The application of the hybrid approach for the management of complex congenital heart defects has also been effectively applied. More recently transcatheter placement of the pulmonary valve has been introduced for severely stenotic and/or regurgitant pulmonary valve in adolescents and adults. It is anticipated that in near future, this procedure would be available for relatively younger patients. In conclusion: last 2 decades have improvised pediatric in
Pakistan Journal of Medical and Health Sciences, Jan 31, 2023
Pakistan Journal of Medical and Health Sciences
Background: The most common issue with transradial cardiac catheterization is radial artery vasos... more Background: The most common issue with transradial cardiac catheterization is radial artery vasospasm. The patient experiences pain and discomfort as a result, the procedure is prolonged, and the interventionist may even be unable to continue. Aim: The aim of the study is to determine the effectiveness of Verapamil, a calcium channel blocker and nitrate, when used together to prevent radial artery spasm during coronary angiographies. Methods: This case control study was held in the Cardiology department of Qazi Hussain Ahmed Medical Complex, Nowshera and Peoples University of Medical and Health Sciences for Women PUMHSW (SBA) Nawabshah for six-months duration from July 2021 to December 2021 including 120 cardiac patients undergoing coronary angiography. The patients were selected by non-probability sampling technique. Patients who were enrolled in the study provided written informed consent. Two groups of patients—control (60) and experimental—were formed (60). Heparin/nitrate was a...
Journal of The Saudi Heart Association, 2019
Transcatheter closure of secundum atrial septal defect is routinely performed under general anest... more Transcatheter closure of secundum atrial septal defect is routinely performed under general anesthesia and transesophageal echocardiography guidance. If patients have good echo windows, the procedure could be performed under transthoracic echo guidance. To evaluate safety and efficacy of the intervention using fluoroscopy and echo guidance. In a case control study design, 180 patients underwent atrial septal defect closure between January 2010 and December 2016. In 32 patients, the intervention was performed under fluoroscopy and transthoracic echo guidance. Our study group consisted of 22 out of 32 patients (&amp;amp;amp;lt;13 years old). For the other 10 patients, we could not find a matching pair. The data of the study group were compared with an age, weight, and height matched group (controls), who underwent the procedure under transesophageal echocardiography guidance. The diameter of the atrial septal defect, septal length, and most of the rims were comparable. The superior rim and inferior rims were longer in the study group. The devices chosen for the cases were larger than the control group. Procedure time and fluoroscopy times were shorter in the study group. Success rate was comparable. On follow-up, both groups had almost no or minimal incidence of residual shunt. We conclude that transcatheter closure of atrial septal defect under fluoroscopy and transthoracic echo guidance is safe and successful in selected patients who have single central atrial septal defect with adequate septal lengths and adequate septal rims, with high incidence of complete occlusion rate.
Pakistan Journal of Medical and Health Sciences, Apr 14, 2023
Pakistan Journal of Medical and Health Sciences, Jan 31, 2023
Pakistan Journal of Medical and Health Sciences
Background: Chest pain is the communal complaint among pediatric age groups. Chest pain due to he... more Background: Chest pain is the communal complaint among pediatric age groups. Chest pain due to heart disease is rare in children and adolescents, with an incidence of less than 6%. History and physical examination may be sufficient to identify the most important etiologies. Aim: The aim of the study is to review various causes of chest pain in young patients admitted to a pediatric cardiology clinic. Method: We retrospectively analyzed the clinical data of our patients visited to emergency or outpatient clinics in our hospital with chest pain from March 2022 to October 2022. A total of 56 patients (36 females and 20 males), aged 5-15 years were included in this study. Follow-up of the patients was carried out by calling all relatives of the patient and asking about the child's condition and chest pain. Clinical history and physical examination were performed. Results: A total of 56 patients between the ages of 5 and 15 were enrolled in the study, with a mean age of 11.78 ± 2.95 ...
Pakistan Journal of Medical and Health Sciences
Background: Soft tissue abscesses is one of the most commonly observed complication in children. ... more Background: Soft tissue abscesses is one of the most commonly observed complication in children. This infection may impart the longer stay at hospital and also increase the cost of medical care. Objective: The study was carried out to find the pattern of organisms and the sensitivity of drugs from the pus produced in soft tissue abscesses among patients. Study design: It is cross-sectional study conducted from January 2020 to November 2022. Material and Methods: The study was conducted at the pediatric department of the Div. HQ teaching hospital Mirpur, Azad Jammu and Kashmir. The study was carried out on 160 patients having at least one abscess on their body. The study also collected information about the predisposing factor that could have led to abscess formation. The site of distribution of the abscess was also analyzed. The abundance of microorganisms that were isolated from the samples of abscesses was also studied. Results: it was found that in most of the patients (45.5%) th...
Pakistan BioMedical Journal
Exercise echocardiography has become a significant tool of non-invasive valuation of coronary art... more Exercise echocardiography has become a significant tool of non-invasive valuation of coronary artery disease (CAD). The Exercise echocardiography and dobutamine stress echocardiography are widely applied methods with different clinical procedures and indications. Objective: To determine the exercise echocardiography and dobutamine stress echocardiography in the assessment of suspected or known coronary artery disease. Methods: 260 consecutive patients endured Stress Echocardiography in the Cardiology department of NICVD Karachi for one-year duration from January 2021 to December 2021. The treadmill was used for Exercise echocardiography applying the Bruce protocol. The standard method was applied for dobutamine stress echocardiography. The Stress Echocardiography was taken as positive on the basis of the appearance of worsening or new wall motion abnormalities. Results: Exercise echocardiography performed by 160 patients and DSE in 100 subjects with mean age of 47.21 and 53.10 years...
International Journal of Advanced Research, Jun 30, 2021
<jats:p>Introduction:Cardiac troponin-I being a sensitive marker of myocardial damage needs... more <jats:p>Introduction:Cardiac troponin-I being a sensitive marker of myocardial damage needs to be analyzed in children undergoing cardiopulmonary by-pass surgery, as perioperative myocardial damage may be a significant factor of postoperative cardiac performance. The present study aims to test the prognostic value of Cardiac troponin-I concerning the early postoperative course after pediatric cardiac surgery. Methods:Cardiac troponin – I levels were measured and correlated with intra and postoperative parameters of thirty-three children undergoing open-heart surgery. The cutoff point for the definition of a high and a low-risk group of Cardiac troponin-I values was set at 25 ng/ml. Results:Overall, cTnI peak value was higher than 25 ng/ml in 21 patients among these,4 died, and two of them were reported with the value of >100 ng/ml. 38.7% of the patients were complicated by different types of arrhythmias. Junctional ectopic tachycardia was the most common type of arrhythmia,while heart block complication was found only in one case, which was temporarily treated by pacing for less than 24 hours. The results showed significant correlation of troponin I values with dobutamine dose mg/kg (p-value=0.043), dobutamine duration (p-value=0.020), creatinine (p-value= 0.002), and internalcare unit stay (p-value= 0.003). Conclusion: The present study confirms that troponin I is specific and sensitive marker of myocardial injury after pediatric cardiac surgery.</jats:p>
Asian Journal of Research in Cardiovascular Diseases, Jun 19, 2021
Asian Journal of Research in Cardiovascular Diseases, Sep 28, 2021
Journal of the Saudi Heart Association
Pakistan Journal of Medical and Health Sciences
COPD has been recognized as a component of the systemic inflammatory syndrome. A commonly used in... more COPD has been recognized as a component of the systemic inflammatory syndrome. A commonly used indicator of the severity and progression of the disease in COPD is expiratory volume per second (FEV1). However, it is weakly associated with symptoms and administration difficulties in elderly patients. Therefore, there is a need for other markers that are better and easy to apply to sick and elderly patients. Plasma fibrinogen can be used as a marker of disease severity. Aim: To estimate the plasma fibrinogen level in patients with COPD and Relationship of levels of plasma fibrinogen with the severity of chronic obstructive pulmonary disease using the BODE classification and GOLD staging. Place and Duration: In the Medicine Unit-II of Jinnah Hospital Lahore for one-year duration from August 2020 to August 2021. Methods: In this cross-sectional study, 110 COPD patients were assessed by measuring plasma fibrinogen correlated with disease severity using the GOLD scale, BODE index and the 6...
This review aims to sum up the improvements witnessed in the field of interventional cardiology d... more This review aims to sum up the improvements witnessed in the field of interventional cardiology during recent times. The last decade has witnessed significant technical advances in the field of radiological imaging and also in interventional cardiology which has helped to offer more non-invasive solutions for the management of congenital heart defects. This has resulted from the use of advanced 3-dimensional fusion imaging instead of conventional 2-dimensional angiography, applying interactive real-time enhancement and using computed tomography and Magnetic Resonance Imaging for interventional procedures. Similarly the introduction of next generation devices, have not only improved the final outcome of the procedure but also has helped in reducing the challenges that were faced before and with the initial generation of devices. These advances have helped not only in reducing the radiation exposure, the use of contrast medium dose but also have resulted in improved early survival. Th...
Here we report an extremely rare case of congenitally corrected transposition of great arteries (... more Here we report an extremely rare case of congenitally corrected transposition of great arteries (CCTGA) associated with Interrupted aortic arch (IAA) type A and ventricular septal defect (VSD) in a preterm baby. Antenatally diagnosed as large VSD and severe Coarctation of aorta. Echocardiogram done revealed that left ventricle with the mitral valve lay on the right side in continuation with the venous right atrium and was connected to the pulmonary artery. The right ventricle lay on the left in continuation with the arterial left atrium and was connected to the aorta. Smallish transverse arch with Interruption of aorta below the left subclavian artery. Large VSD with bidirectional shunt. Small PDA with restrictive right to left flow. As far we know, only one similar case was reported earlier by Cottrell, at el. (4). At that time the initial diagnosis was done by cardiac angiography as 2D color echocardiography was not available at their center, after one year they were able to use e...