Dhavee Sirivongs | Khon Kaen University (original) (raw)

Papers by Dhavee Sirivongs

Nephro-Urology Monthly

Background: Lupus nephritis (LN) is the most common etiology of secondary glomerulonephritis. Sev... more Background: Lupus nephritis (LN) is the most common etiology of secondary glomerulonephritis. Several studies have identified the risk of LN in SLE patients. However, clinical factors predictive of LN in patients who underwent kidney biopsy for the first time was limited if there was no previous history of SLE. Objectives: This study aimed to investigate the clinical factors predictive of LN by kidney biopsy regardless of SLE history. Methods: We conducted a retrospective study between January 2012 and May 2013. The inclusion criteria were adults over 18 years old who underwent the first kidney biopsy in their lives. Participants were divided into two groups according to renal pathology (LN and non-LN group). Predictors for LN in those without history of SLE were executed by using by logistic regression analysis. Results: In total, there were 205 patients included in the study. LN was defined in 68 patients (33.2%) and the other 137 patients (66.8%) were non-LN. The LN group had a significantly lower mean age (33.6 years vs. 44.2 years; P value < 0.01) and higher eGFR (79.0 vs. 62.3 mL/min; P value 0.05) than the non-LN group. After adjustment, only three factors were independently associated with LN, including eGFR, history of SLE, and RBC in urine > 10 cells/HP. Without history of SLE, ANA was the only independent factor in predicting LN with ORs (95% CI) of 14.5 (1.4, 150.8). Conclusions: ANA should be tested in all patients who underwent kidney biopsy regardless of previous history of SLE.

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

The peritoneal dialysis First (PD-First) policy means that PD is the first modality of dialysis c... more The peritoneal dialysis First (PD-First) policy means that PD is the first modality of dialysis chosen for patients with end-stage renal disease (ESRD), as put forth by the Universal Health Coverage (UHC) scheme. It was initiated in Thailand in 2008. Our aim is to analyze patient survival, technique survival, and associated factors. Data of PD patients from January 2008 to November 2016 were studied. We calculated patient and technique survival rates (censored for death and kidney transplantation). Factors associated with survival were analyzed by the Cox proportional hazard model. Patient and technique survival rates between 2008 - 2012 and 2013 - 2016 were compared. Our study included 11,477 patients. The mean (standard deviation [SD]) age at initiation of PD was 54.0 (14.4) years. The level of education in 85.2% of cases was illiterate or primary school. A total of 60.9% of patients developed ESRD secondary to diabetes. The 1- to 5-year patient survival rates were 82.6, 71.8, 64....

Nephrology Dialysis Transplantation

Nephrology Dialysis Transplantation, 2015

BMC nephrology, Nov 9, 2016

Experimental studies have linked peritubular capillary (PTC) loss with progression of chronic kid... more Experimental studies have linked peritubular capillary (PTC) loss with progression of chronic kidney disease. Minimal information on PTC in lupus nephritis (LN) has been reported. We therefore evaluated the PTC area in different classes of LN and determined if specific clinical characteristics correlated with PTC changes. Renal biopsies of 253 subjects with LN (categorized using the ISN/RPS 2003 classification) and 13 normal renal donors (the controls) were retrospectively evaluated for PTC morphology by staining for CD31 with immunohistochemistry method. The percent positive area of PTC (% PTC) was correlated with serum and urinary measures of renal function and renal pathology. Significant PTC loss was observed in all classes of LN compared to controls. The % PTC area was highest in controls (7.64±1.48 %) with levels of 1.95±1.50, 4.16±3.85, 4.19±4.45, 5.02±1.79, and 4.45±3.75 in classes II, III, IV, IV combined with V and V, respectively (all p values < 0.05). The lowest PTC d...

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015

The purpose of this study was to investigate the immediate effects of traditional Thai massage (T... more The purpose of this study was to investigate the immediate effects of traditional Thai massage (TTM) on psychological stress and heart rate variability (HRV). Thirty healthy participants were randomly allocated in two groups, a TTM group (n = 15) who received a 1-hour session with moderate pressure of whole body TTM or a control group (n=15) who rested on the bedfor 1 hour All ofthem were given a 10-minute mental arithmetic test to induce psychological stress after which they received a 1-hour session of TTM or bed rest. Psychological stress and HR V were measured at baseline and immediately after mental arithmetic test, and immediately after TTM or bed rest. The studyfound that psychological stress was signficantly increased (p<0.05) after mental arithmetic test in both groups. Comparison on these measures between immediately after mental arithmetic test and after TTM or bed rest revealed that psychological stress was significantly decreased (p<0.05) and HR Vwas significantly...

A new quality of life measure, apart of the National Health and Welfare 2003 survey, is a promisi... more A new quality of life measure, apart of the National Health and Welfare 2003 survey, is a promising tool for outcome evaluation of clinical practice due to its brevity, validity, reliability, and providing easy interpretation against general population norm-based scores. The measure consisting of 9-items, and so called 9-item Thai Health status Assessment Instrument (9-THAI) was used to assess its validity and reliability in patients on renal replacement therapy (RRT). Three hundred and two patients on RRT who visited Srinagarind Hospital from March to May 2005 were studied Convergent and divergent validity were assessed using SF-36 as the concurrent measure. Concurrent validity was also assessed using hematocrit level and hospitalization history in the last year as concurrent clinical measures. Test-retest reliability was studied by repeated measure within one 1 month. Responsiveness of 9-THAI was studied in patients who reported health improvement. Results of correlations between 9-THAI and SF-36 domains were as hypothesized 9-THAI scores were significantly correlated with hematocrit level and hospitalization history. The results confirmed the validity of 9-THAI for use as a quality of life measure. Intraclass correlation coefficients of 9-THAI scores in stable patients were satisfactory. Among patients on RRT who reported overall health improvement, 9-THAI scores significantly increased, thus adding further evidence of the responsiveness of 9-THAI. The 9-THAI is a valid and reliable generic health status measure that can be used as an ideal core in a battery of quality of life measures in clinical practice for patients on RRT.

ศรีนครินทร์เวชสาร, 2007

• aeƒµ'°√√¡ ‡™' ß ÿ ¢¿"ae¢Õß ¡"™'°Õß §å°√•ae∑¬å ‚√ßae¬"∫"≈»√' π §√' π∑√å π' aeπ∏å µâ π©∫-∫ • Orig... more • aeƒµ'°√√¡ ‡™' ß ÿ ¢¿"ae¢Õß ¡"™'°Õß §å°√•ae∑¬å ‚√ßae¬"∫"≈»√' π §√' π∑√å π' aeπ∏å µâ π©∫-∫ • Original Article aeƒµ'°√√¡ ‡™' ß ÿ ¢¿"ae¢Õß ¡"™'°Õß §å°√•ae∑¬å ‚√ßae¬"∫"≈»√' π §√' π∑√å §≥-•ae∑¬»" µ√å ¡À"«' ∑¬"≈-¬¢Õπ•°à π

Medical Science Monitor Basic Research, 2015

Departmental sources Background: Stress can cause psychological and physiological changes. Many s... more Departmental sources Background: Stress can cause psychological and physiological changes. Many studies revealed that massage can decrease stress. However, traditional Thai massage has not been well researched in this regard. The purpose of this study was to investigate the immediate effects of traditional Thai massage (TTM) on salivary alpha-amylase levels (sAA), heart rate variability (HRV), autonomic nervous system (ANS) function, and plasma renin activity (PRA). Material/Methods: Twenty-nine healthy participants were randomly allocated into either a traditional Thai massage (TTM) group or Control (C) group, after which they were switched to the other group with a 2-week wash-out period. Each of them was given a 10-minute mental arithmetic test to induce psychological stress before a 1-hour session of TTM or rest. Results: Within-groups comparison revealed that sAA was significantly decreased (p<0.05) in the TTM group but not in the C group. HRV and ANS function were significantly increased (p<0.05) and PRA was significantly decreased (p<0.05) in both groups. However, low frequency per high frequency ratio (LF/HF ratio) and ANS balance status were not changed. Only sAA was found to be significantly different between groups (p<0.05). Conclusions: We conclude that both TTM and rest can reduce psychological stress, as indicated by decreased sAA levels, increased parasympathetic activity, decreased sympathetic activity, and decreased PRA. However, TTM may have a modest effect on stress reduction as indicated by a reduced sAA.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet

Completeness of urine collection and food intake can influence urinary biochemical composition (U... more Completeness of urine collection and food intake can influence urinary biochemical composition (UC). These variables depend in part upon whether patients are ambulatory or in-patients. This study was conducted to see whether the change in the place of urine collection from village to hospital would affect UC. Six consecutive 24-hour urinary measurements for creatinine (cr), urea nitrogen (urea-N), calcium (Ca) and sodium (Na) were made in 8 normal male volunteers. The first three 24-hour urine specimens (UV) were collected at home and the last three when they were in the hospital. Food consumed while subjects were in their village was recorded and prepared in the same manner for the same subjects when they were at the hospital. Comparing the values between at the village and at the hospital, the urinary cr, urea-N, Ca and Na increased disproportionately with the average hospital/village ratio of 1.17, 1.20, 1.50 and 1.09 respectively. The median of relative rate of increase of urinary urea-N, Na and Ca compared to that of cr, being expressed as (hospital/village UV urea-N)/(hospital/village UV cr), (hospital/village UV Na)/(hospital/village UV cr) and (hospital/village UV Ca)/(hospital/village UV cr) respectively, were 1.00, 0.97 and 1.30 respectively. The data indicated that the change in urinary urea-N and Na when the subjects were at the hospital was mainly due to completeness of urine collection. In contrast, marked increment in UV Ca at the hospital was accounted for factor(s) by other than completeness of urine collection per se. The difference in dietary Ca intake between village and hospital might have been responsible in part for the changes.(ABSTRACT TRUNCATED AT 250 WORDS)

The American journal of physiology

ABSTRACT

Cancer Research

Renal carcinoma cells removed surgically from two patients (one primary tumor and one bone metast... more Renal carcinoma cells removed surgically from two patients (one primary tumor and one bone metastasis) were maintained in short-term culture. Media conditioned by these cells contained calcium oxalate monohydrate crystal growth inhibitor, a glycoprotein named nephrocalcin (NC). NC was also detected in both cell lines by an enzyme-linked immunosorbent assay using anti-NC antibody raised in rabbits. The glycoprotein was purified from the culture medium and found to have an amino acid composition similar to that of normal human urinary NC. However, NC from the renal carcinoma cells, isolated in multiple forms by DEAE-cellulose column chromatography, contained larger amounts of carbohydrate residues than normal NC. Purified NCs showed a dis sociation constant of 10 6to III *M toward calcium oxalate monohydrate crystal. Three renal carcinoma cell lines maintained in long-term culture failed to produce NC. Our study demonstrates that NC is produced by renal cell carcinoma cells (in vitro) from primary and metastatic tumors. Preliminary data suggest that urinary levels of NC corresponded with disease progression in patients with metastatic disease, suggesting that NC may be useful clinically as a tumor marker.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet

Objective: To evaluate patient and technique survival, and to analyze factors influencing surviva... more Objective: To evaluate patient and technique survival, and to analyze factors influencing survival in a large Thai CAPD program. Material and Method: A single center, retrospective, observational cohort study was carried out to examine the baseline factors affecting patient and technique survival. Results: From January 1995 to December 2005, 322 incident CAPD patients were recruited for study. One hundred and thirteen patients (35.1%) died during the study period of 7,706 patient-months. Median patient survival time was 46.4 months. The major cause of death was related to infection. In multivariate analysis, only age at enrollment and baseline serum albumin were strong risk factors of death. Median technique survival was 41.2 months. The major cause of technique failure was peritoneal dialysis related infection. History of peritonitis, baseline serum albumin, and dialysis commencement in recent era were technique failure predictors. A neutral effect of self and caregiver performer was observed in the present study. Conclusion: Patient survival in the presented institute is similar to that reported in Western countries. Age and baseline serum albumin were the strongest predictors of death.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2011

Universal coverage (UC) scheme is a reformed national healthcare insurance that has been set up s... more Universal coverage (UC) scheme is a reformed national healthcare insurance that has been set up since the year 2002 and covers more than 80% of Thai population who are self-employed and do not work as government employees. Initially, this scheme offered only basic and comprehensive healthcare while renal replacement therapy (RRT), the financial cost of which was high, was not included. Without the support from the government healthcare insurance, the patients and their families will become insolvency. The benefit of peritoneal dialysis (PD) over hemodialysis (HD) has been shown in terms of medical expenses and cost-effectiveness. The "PD First" policy in Thailand has been implemented on January 1st 2008 as a model of initial treatment of end stage renal disease (ESRD) patients under the UC scheme. During the year 2008-2011, 12,753 cases, 6,177 were male and 6,576 were female, registered in this modality. The technical survivals at 1, 2 and 3 years were 92, 85 and 80%, resp...

Khon Kaen University Journal (Graduate Studies), 2013

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

Nephro-Urology Monthly

Background: Lupus nephritis (LN) is the most common etiology of secondary glomerulonephritis. Sev... more Background: Lupus nephritis (LN) is the most common etiology of secondary glomerulonephritis. Several studies have identified the risk of LN in SLE patients. However, clinical factors predictive of LN in patients who underwent kidney biopsy for the first time was limited if there was no previous history of SLE. Objectives: This study aimed to investigate the clinical factors predictive of LN by kidney biopsy regardless of SLE history. Methods: We conducted a retrospective study between January 2012 and May 2013. The inclusion criteria were adults over 18 years old who underwent the first kidney biopsy in their lives. Participants were divided into two groups according to renal pathology (LN and non-LN group). Predictors for LN in those without history of SLE were executed by using by logistic regression analysis. Results: In total, there were 205 patients included in the study. LN was defined in 68 patients (33.2%) and the other 137 patients (66.8%) were non-LN. The LN group had a significantly lower mean age (33.6 years vs. 44.2 years; P value < 0.01) and higher eGFR (79.0 vs. 62.3 mL/min; P value 0.05) than the non-LN group. After adjustment, only three factors were independently associated with LN, including eGFR, history of SLE, and RBC in urine > 10 cells/HP. Without history of SLE, ANA was the only independent factor in predicting LN with ORs (95% CI) of 14.5 (1.4, 150.8). Conclusions: ANA should be tested in all patients who underwent kidney biopsy regardless of previous history of SLE.

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

The peritoneal dialysis First (PD-First) policy means that PD is the first modality of dialysis c... more The peritoneal dialysis First (PD-First) policy means that PD is the first modality of dialysis chosen for patients with end-stage renal disease (ESRD), as put forth by the Universal Health Coverage (UHC) scheme. It was initiated in Thailand in 2008. Our aim is to analyze patient survival, technique survival, and associated factors. Data of PD patients from January 2008 to November 2016 were studied. We calculated patient and technique survival rates (censored for death and kidney transplantation). Factors associated with survival were analyzed by the Cox proportional hazard model. Patient and technique survival rates between 2008 - 2012 and 2013 - 2016 were compared. Our study included 11,477 patients. The mean (standard deviation [SD]) age at initiation of PD was 54.0 (14.4) years. The level of education in 85.2% of cases was illiterate or primary school. A total of 60.9% of patients developed ESRD secondary to diabetes. The 1- to 5-year patient survival rates were 82.6, 71.8, 64....

Nephrology Dialysis Transplantation

Nephrology Dialysis Transplantation, 2015

BMC nephrology, Nov 9, 2016

Experimental studies have linked peritubular capillary (PTC) loss with progression of chronic kid... more Experimental studies have linked peritubular capillary (PTC) loss with progression of chronic kidney disease. Minimal information on PTC in lupus nephritis (LN) has been reported. We therefore evaluated the PTC area in different classes of LN and determined if specific clinical characteristics correlated with PTC changes. Renal biopsies of 253 subjects with LN (categorized using the ISN/RPS 2003 classification) and 13 normal renal donors (the controls) were retrospectively evaluated for PTC morphology by staining for CD31 with immunohistochemistry method. The percent positive area of PTC (% PTC) was correlated with serum and urinary measures of renal function and renal pathology. Significant PTC loss was observed in all classes of LN compared to controls. The % PTC area was highest in controls (7.64±1.48 %) with levels of 1.95±1.50, 4.16±3.85, 4.19±4.45, 5.02±1.79, and 4.45±3.75 in classes II, III, IV, IV combined with V and V, respectively (all p values < 0.05). The lowest PTC d...

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015

The purpose of this study was to investigate the immediate effects of traditional Thai massage (T... more The purpose of this study was to investigate the immediate effects of traditional Thai massage (TTM) on psychological stress and heart rate variability (HRV). Thirty healthy participants were randomly allocated in two groups, a TTM group (n = 15) who received a 1-hour session with moderate pressure of whole body TTM or a control group (n=15) who rested on the bedfor 1 hour All ofthem were given a 10-minute mental arithmetic test to induce psychological stress after which they received a 1-hour session of TTM or bed rest. Psychological stress and HR V were measured at baseline and immediately after mental arithmetic test, and immediately after TTM or bed rest. The studyfound that psychological stress was signficantly increased (p<0.05) after mental arithmetic test in both groups. Comparison on these measures between immediately after mental arithmetic test and after TTM or bed rest revealed that psychological stress was significantly decreased (p<0.05) and HR Vwas significantly...

A new quality of life measure, apart of the National Health and Welfare 2003 survey, is a promisi... more A new quality of life measure, apart of the National Health and Welfare 2003 survey, is a promising tool for outcome evaluation of clinical practice due to its brevity, validity, reliability, and providing easy interpretation against general population norm-based scores. The measure consisting of 9-items, and so called 9-item Thai Health status Assessment Instrument (9-THAI) was used to assess its validity and reliability in patients on renal replacement therapy (RRT). Three hundred and two patients on RRT who visited Srinagarind Hospital from March to May 2005 were studied Convergent and divergent validity were assessed using SF-36 as the concurrent measure. Concurrent validity was also assessed using hematocrit level and hospitalization history in the last year as concurrent clinical measures. Test-retest reliability was studied by repeated measure within one 1 month. Responsiveness of 9-THAI was studied in patients who reported health improvement. Results of correlations between 9-THAI and SF-36 domains were as hypothesized 9-THAI scores were significantly correlated with hematocrit level and hospitalization history. The results confirmed the validity of 9-THAI for use as a quality of life measure. Intraclass correlation coefficients of 9-THAI scores in stable patients were satisfactory. Among patients on RRT who reported overall health improvement, 9-THAI scores significantly increased, thus adding further evidence of the responsiveness of 9-THAI. The 9-THAI is a valid and reliable generic health status measure that can be used as an ideal core in a battery of quality of life measures in clinical practice for patients on RRT.

ศรีนครินทร์เวชสาร, 2007

• aeƒµ'°√√¡ ‡™' ß ÿ ¢¿"ae¢Õß ¡"™'°Õß §å°√•ae∑¬å ‚√ßae¬"∫"≈»√' π §√' π∑√å π' aeπ∏å µâ π©∫-∫ • Orig... more • aeƒµ'°√√¡ ‡™' ß ÿ ¢¿"ae¢Õß ¡"™'°Õß §å°√•ae∑¬å ‚√ßae¬"∫"≈»√' π §√' π∑√å π' aeπ∏å µâ π©∫-∫ • Original Article aeƒµ'°√√¡ ‡™' ß ÿ ¢¿"ae¢Õß ¡"™'°Õß §å°√•ae∑¬å ‚√ßae¬"∫"≈»√' π §√' π∑√å §≥-•ae∑¬»" µ√å ¡À"«' ∑¬"≈-¬¢Õπ•°à π

Medical Science Monitor Basic Research, 2015

Departmental sources Background: Stress can cause psychological and physiological changes. Many s... more Departmental sources Background: Stress can cause psychological and physiological changes. Many studies revealed that massage can decrease stress. However, traditional Thai massage has not been well researched in this regard. The purpose of this study was to investigate the immediate effects of traditional Thai massage (TTM) on salivary alpha-amylase levels (sAA), heart rate variability (HRV), autonomic nervous system (ANS) function, and plasma renin activity (PRA). Material/Methods: Twenty-nine healthy participants were randomly allocated into either a traditional Thai massage (TTM) group or Control (C) group, after which they were switched to the other group with a 2-week wash-out period. Each of them was given a 10-minute mental arithmetic test to induce psychological stress before a 1-hour session of TTM or rest. Results: Within-groups comparison revealed that sAA was significantly decreased (p<0.05) in the TTM group but not in the C group. HRV and ANS function were significantly increased (p<0.05) and PRA was significantly decreased (p<0.05) in both groups. However, low frequency per high frequency ratio (LF/HF ratio) and ANS balance status were not changed. Only sAA was found to be significantly different between groups (p<0.05). Conclusions: We conclude that both TTM and rest can reduce psychological stress, as indicated by decreased sAA levels, increased parasympathetic activity, decreased sympathetic activity, and decreased PRA. However, TTM may have a modest effect on stress reduction as indicated by a reduced sAA.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet

Completeness of urine collection and food intake can influence urinary biochemical composition (U... more Completeness of urine collection and food intake can influence urinary biochemical composition (UC). These variables depend in part upon whether patients are ambulatory or in-patients. This study was conducted to see whether the change in the place of urine collection from village to hospital would affect UC. Six consecutive 24-hour urinary measurements for creatinine (cr), urea nitrogen (urea-N), calcium (Ca) and sodium (Na) were made in 8 normal male volunteers. The first three 24-hour urine specimens (UV) were collected at home and the last three when they were in the hospital. Food consumed while subjects were in their village was recorded and prepared in the same manner for the same subjects when they were at the hospital. Comparing the values between at the village and at the hospital, the urinary cr, urea-N, Ca and Na increased disproportionately with the average hospital/village ratio of 1.17, 1.20, 1.50 and 1.09 respectively. The median of relative rate of increase of urinary urea-N, Na and Ca compared to that of cr, being expressed as (hospital/village UV urea-N)/(hospital/village UV cr), (hospital/village UV Na)/(hospital/village UV cr) and (hospital/village UV Ca)/(hospital/village UV cr) respectively, were 1.00, 0.97 and 1.30 respectively. The data indicated that the change in urinary urea-N and Na when the subjects were at the hospital was mainly due to completeness of urine collection. In contrast, marked increment in UV Ca at the hospital was accounted for factor(s) by other than completeness of urine collection per se. The difference in dietary Ca intake between village and hospital might have been responsible in part for the changes.(ABSTRACT TRUNCATED AT 250 WORDS)

The American journal of physiology

ABSTRACT

Cancer Research

Renal carcinoma cells removed surgically from two patients (one primary tumor and one bone metast... more Renal carcinoma cells removed surgically from two patients (one primary tumor and one bone metastasis) were maintained in short-term culture. Media conditioned by these cells contained calcium oxalate monohydrate crystal growth inhibitor, a glycoprotein named nephrocalcin (NC). NC was also detected in both cell lines by an enzyme-linked immunosorbent assay using anti-NC antibody raised in rabbits. The glycoprotein was purified from the culture medium and found to have an amino acid composition similar to that of normal human urinary NC. However, NC from the renal carcinoma cells, isolated in multiple forms by DEAE-cellulose column chromatography, contained larger amounts of carbohydrate residues than normal NC. Purified NCs showed a dis sociation constant of 10 6to III *M toward calcium oxalate monohydrate crystal. Three renal carcinoma cell lines maintained in long-term culture failed to produce NC. Our study demonstrates that NC is produced by renal cell carcinoma cells (in vitro) from primary and metastatic tumors. Preliminary data suggest that urinary levels of NC corresponded with disease progression in patients with metastatic disease, suggesting that NC may be useful clinically as a tumor marker.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet

Objective: To evaluate patient and technique survival, and to analyze factors influencing surviva... more Objective: To evaluate patient and technique survival, and to analyze factors influencing survival in a large Thai CAPD program. Material and Method: A single center, retrospective, observational cohort study was carried out to examine the baseline factors affecting patient and technique survival. Results: From January 1995 to December 2005, 322 incident CAPD patients were recruited for study. One hundred and thirteen patients (35.1%) died during the study period of 7,706 patient-months. Median patient survival time was 46.4 months. The major cause of death was related to infection. In multivariate analysis, only age at enrollment and baseline serum albumin were strong risk factors of death. Median technique survival was 41.2 months. The major cause of technique failure was peritoneal dialysis related infection. History of peritonitis, baseline serum albumin, and dialysis commencement in recent era were technique failure predictors. A neutral effect of self and caregiver performer was observed in the present study. Conclusion: Patient survival in the presented institute is similar to that reported in Western countries. Age and baseline serum albumin were the strongest predictors of death.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2011

Universal coverage (UC) scheme is a reformed national healthcare insurance that has been set up s... more Universal coverage (UC) scheme is a reformed national healthcare insurance that has been set up since the year 2002 and covers more than 80% of Thai population who are self-employed and do not work as government employees. Initially, this scheme offered only basic and comprehensive healthcare while renal replacement therapy (RRT), the financial cost of which was high, was not included. Without the support from the government healthcare insurance, the patients and their families will become insolvency. The benefit of peritoneal dialysis (PD) over hemodialysis (HD) has been shown in terms of medical expenses and cost-effectiveness. The "PD First" policy in Thailand has been implemented on January 1st 2008 as a model of initial treatment of end stage renal disease (ESRD) patients under the UC scheme. During the year 2008-2011, 12,753 cases, 6,177 were male and 6,576 were female, registered in this modality. The technical survivals at 1, 2 and 3 years were 92, 85 and 80%, resp...

Khon Kaen University Journal (Graduate Studies), 2013

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis