Anders Gade | University of Copenhagen (original) (raw)
Papers by Anders Gade
Psychopathology, Jan 11, 2015
The personality trait of neuroticism is strongly related to depression, but depression is etiolog... more The personality trait of neuroticism is strongly related to depression, but depression is etiologically heterogeneous. Late-onset depression (LOD) may be more closely related to vascular factors, and previous studies of neuroticism in LOD versus early-onset depression (EOD) have not been consistent. We examined neuroticism, extraversion and perceived stress in 88 fully remitted depressed patients with a mean age of 60 years and with a history of hospitalization for major depressive disorder. Patients were divided into those with onset after and those with onset before 50 years of age (LOD and EOD, respectively), and the two groups were compared both with each other and with matched control groups of healthy subjects. EOD patients showed increased levels of neuroticism in comparison with both LOD and matched controls, who did not differ. The association between age of onset and neuroticism was confirmed in analyses based on age of depression onset as a continuous variable. Neuroticis...
Ugeskrift for laeger
Progressive dementia has been described in AIDS patients as the most significant neurologic compl... more Progressive dementia has been described in AIDS patients as the most significant neurologic complication, related to HIV-1 infection directly rather than to opportunistic infections. As the virus seems to enter brain early in the course of infection, incipient dementia or subclinical cognitive impairment have been assumed to occur in otherwise asymptomatic HIV-1 seropositive individuals. A review of relevant neuropsychological studies indicates that this suspicion receives no support in large well-controlled studies. The natural history of AIDS dementia is still not clearly delineated, but encephalopathy seems to develop only with or after systemic immunosuppression.
... Litteratur: Crawford, JR, Parker, DM, and McKinlay, WW (Eds.).(1992). A handbook of neuropsyc... more ... Litteratur: Crawford, JR, Parker, DM, and McKinlay, WW (Eds.).(1992). A handbook of neuropsychological assessment. Hove: Erlbaum. Lezak, MD (1995). ... Cognitive neuropsychology: A clinical introduction. San Diego: Academic Press. Mortensen, EL, & Gade, A. (1993). ...
Neuropsykologiske opslag og temaer til "Gads psykologileksikon"... more Neuropsykologiske opslag og temaer til "Gads psykologileksikon" (redigeret af Jens Bjerg; udkommet på Gads Forlag 2004). ... Alzheimers sygdom er opkaldt efter den tyske neuropsykiaterAlois Alzheimer (1864-1915), som i 1907 beskrev dels forløbet hos en yngre patient med ...
Journal of Clinical and Experimental Neuropsychology, Aug 9, 2010
Stroop's test and the Verbal Fluency test are commonly argued to be measures of the integrity of ... more Stroop's test and the Verbal Fluency test are commonly argued to be measures of the integrity of the prefrontal cortex. This assumption has only to some degree been con®rmed by lesion studies. In the present study, Positron Emission Tomography (PET) with H 2
Neuropsychology, Jan 24, 2015
Emotion recognition has been widely studied in Huntington disease (HD), but only a few studies ha... more Emotion recognition has been widely studied in Huntington disease (HD), but only a few studies have investigated more complex social cognition and, when so, exclusively in manifest HD. The present study sought to investigate social-cognitive functions in a large, consecutive cohort of premanifest and manifest HD gene expansion carriers using tests assessing sarcasm detection, theory of mind (ToM), and emotion recognition. Fifty manifest, 50 premanifest HD gene expansion carriers, and 39 at risk gene expansion negative healthy controls were included. All participants were tested with sarcasm detection, ToM, and emotion recognition tasks. Between-group comparisons of test performances and correlation analyses of test performances and disease burden scores were made. Group comparisons showed significant differences in performances on the social-cognitive tests between manifest HD gene expansion carriers and healthy controls, but differences in performances between premanifest HD gene e...
Surgical neurology, 1982
All patients with ruptured aneurysms admitted to neurosurgical departments in Denmark after April... more All patients with ruptured aneurysms admitted to neurosurgical departments in Denmark after April, 1978, are the subjects in the prospective study that includes neuropsychological examinations. Data from 48 patients with aneurysms of the anterior communicating artery have been analyzed. Trapping of the aneurysm was done in 11 patients and resulted in an amnesic syndrome in 9. Thirty-seven patients were operated upon by ligation of the neck of the aneurysm or similar procedures, resulting in 6 cases of amnesia. Trapping invariably disrupts blood supply through newly described dorsal perforating branches from the anterior communicating artery. These perforating branches may supply areas of vital importance to memory function.
Psychopathology, Jan 11, 2015
The personality trait of neuroticism is strongly related to depression, but depression is etiolog... more The personality trait of neuroticism is strongly related to depression, but depression is etiologically heterogeneous. Late-onset depression (LOD) may be more closely related to vascular factors, and previous studies of neuroticism in LOD versus early-onset depression (EOD) have not been consistent. We examined neuroticism, extraversion and perceived stress in 88 fully remitted depressed patients with a mean age of 60 years and with a history of hospitalization for major depressive disorder. Patients were divided into those with onset after and those with onset before 50 years of age (LOD and EOD, respectively), and the two groups were compared both with each other and with matched control groups of healthy subjects. EOD patients showed increased levels of neuroticism in comparison with both LOD and matched controls, who did not differ. The association between age of onset and neuroticism was confirmed in analyses based on age of depression onset as a continuous variable. Neuroticis...
Ugeskrift for laeger
Progressive dementia has been described in AIDS patients as the most significant neurologic compl... more Progressive dementia has been described in AIDS patients as the most significant neurologic complication, related to HIV-1 infection directly rather than to opportunistic infections. As the virus seems to enter brain early in the course of infection, incipient dementia or subclinical cognitive impairment have been assumed to occur in otherwise asymptomatic HIV-1 seropositive individuals. A review of relevant neuropsychological studies indicates that this suspicion receives no support in large well-controlled studies. The natural history of AIDS dementia is still not clearly delineated, but encephalopathy seems to develop only with or after systemic immunosuppression.
... Litteratur: Crawford, JR, Parker, DM, and McKinlay, WW (Eds.).(1992). A handbook of neuropsyc... more ... Litteratur: Crawford, JR, Parker, DM, and McKinlay, WW (Eds.).(1992). A handbook of neuropsychological assessment. Hove: Erlbaum. Lezak, MD (1995). ... Cognitive neuropsychology: A clinical introduction. San Diego: Academic Press. Mortensen, EL, & Gade, A. (1993). ...
Neuropsykologiske opslag og temaer til "Gads psykologileksikon"... more Neuropsykologiske opslag og temaer til "Gads psykologileksikon" (redigeret af Jens Bjerg; udkommet på Gads Forlag 2004). ... Alzheimers sygdom er opkaldt efter den tyske neuropsykiaterAlois Alzheimer (1864-1915), som i 1907 beskrev dels forløbet hos en yngre patient med ...
Journal of Clinical and Experimental Neuropsychology, Aug 9, 2010
Stroop's test and the Verbal Fluency test are commonly argued to be measures of the integrity of ... more Stroop's test and the Verbal Fluency test are commonly argued to be measures of the integrity of the prefrontal cortex. This assumption has only to some degree been con®rmed by lesion studies. In the present study, Positron Emission Tomography (PET) with H 2
Neuropsychology, Jan 24, 2015
Emotion recognition has been widely studied in Huntington disease (HD), but only a few studies ha... more Emotion recognition has been widely studied in Huntington disease (HD), but only a few studies have investigated more complex social cognition and, when so, exclusively in manifest HD. The present study sought to investigate social-cognitive functions in a large, consecutive cohort of premanifest and manifest HD gene expansion carriers using tests assessing sarcasm detection, theory of mind (ToM), and emotion recognition. Fifty manifest, 50 premanifest HD gene expansion carriers, and 39 at risk gene expansion negative healthy controls were included. All participants were tested with sarcasm detection, ToM, and emotion recognition tasks. Between-group comparisons of test performances and correlation analyses of test performances and disease burden scores were made. Group comparisons showed significant differences in performances on the social-cognitive tests between manifest HD gene expansion carriers and healthy controls, but differences in performances between premanifest HD gene e...
Surgical neurology, 1982
All patients with ruptured aneurysms admitted to neurosurgical departments in Denmark after April... more All patients with ruptured aneurysms admitted to neurosurgical departments in Denmark after April, 1978, are the subjects in the prospective study that includes neuropsychological examinations. Data from 48 patients with aneurysms of the anterior communicating artery have been analyzed. Trapping of the aneurysm was done in 11 patients and resulted in an amnesic syndrome in 9. Thirty-seven patients were operated upon by ligation of the neck of the aneurysm or similar procedures, resulting in 6 cases of amnesia. Trapping invariably disrupts blood supply through newly described dorsal perforating branches from the anterior communicating artery. These perforating branches may supply areas of vital importance to memory function.