Dr. Sandhu G. Joseph | Kerala University Of Health Sciences (original) (raw)
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Papers by Dr. Sandhu G. Joseph
Jwara is the first and foremost among all somatic diseases. Although an independent disease, it i... more Jwara is the first and foremost among all somatic diseases. Although an independent disease, it is also seen manifested in the form of premonitory symptom, symptom and causative factor of various disorders. 2019-20 has witnessed a new pandemic identified as Corona virus (COVID-19) with adverse health issues. In proportion to the wide variety of diseases, viral vaccines are very few, that too with adverse effects. Hence there is an urgent need of most promising Indigenous drugs with antipyretic and anti-viral activity in the current scenario. A critical analysis is made to explore the Jwarahara Yogas of classics to unfold the Antiviral, Antipyretic, Antioxidant and Immunomodulatory potential of phytochemicals in formulations. An attempt has been made to explore the antiviral and antipyretic potential of Amrutotharam Kashayam, one of the most popular and widely used Jwarahara yoga in classics. The review will definitely give new insights on the synergistic actions of phytochemicals in formulations to revalidate the clinical evidences and will throw lime light on repurposing of the documented novel drugs and combinations in classics to offer unique preventive strategies and therapeutic solutions to the present pandemic and emerging viral infections.
International journal of research in ayurveda and pharmacy, 2021
Jwara is the first and foremost among all somatic diseases Although an independent disease, it is... more Jwara is the first and foremost among all somatic diseases Although an independent disease, it is also seen manifested in the form of premonitory symptom, symptom and causative factor of various disorders 2019-20 has witnessed a new pandemic identified as Corona virus (COVID-19) with adverse health issues In proportion to the wide variety of diseases, viral vaccines are very few, that too with adverse effects Hence there is an urgent need of most promising Indigenous drugs with antipyretic and anti-viral activity in the current scenario A critical analysis is made to explore the Jwarahara Yogas of classics to unfold the Antiviral, Antipyretic, Antioxidant and Immunomodulatory potential of phytochemicals in formulations An attempt has been made to explore the antiviral and antipyretic potential of Amrutotharam Kashayam, one of the most popular and widely used Jwarahara yoga in classics The review will definitely give new insights on the synergistic actions of phytochemicals in formul...
Journal of Ayurveda Medical Sciences, 2017
Introduction: Ficus religiosa Linn. (Moraceae) is a pharmacopoeial drug of Ayurveda, commonly kno... more Introduction: Ficus religiosa Linn. (Moraceae) is a pharmacopoeial drug of Ayurveda, commonly known as peepal in Hindi. This is a source drug for the plant Ashvattha in Ayurveda. The plant has a religious and ancient history found all over India. The tree is found to be sacred because of its religious rituals. It has also got the importance in medicinal science and hence used in different systems of medicine such as Ayurveda, Unani and Homeopathy. The drug is considered to be precious because of its wide therapeutic efficacy. The different parts of this plant like bark, leaves, tender shoots, fruit, seed, latex etc. are being used for different ailments since ages. Acharyas in samhita have mentioned the use of Ashvattha in various contexts. Vata rakta is one such disease where the bark kashaya of Ashvattha is used. One of the correlations for vata rakta in modern science is gout in which one of the parameters assessed is hyperurecemia. Here the pharmacological study is conducted as a preclinical study by using different experimental models. Methods: The experimental study was carried out in the Pharmacology department of SDM Centre for Research in Ayurveda and Allied Sciences, Udupi. The anti-hyperuricemic activity has been assessed by Potassium oxonate induced hyperuricemic model. Result: The experimental study had shown bark kashaya as extremely significant values in serum uric acid and urine uric acid parameters in anti-hyperuricemic activity. Conclusion: The experiment has shown Ashvattha bark to have potential antihyperuricemic activity.
IJRAP, 2021
Jwara is the first and foremost among all somatic diseases. Although an independent disease, it i... more Jwara is the first and foremost among all somatic diseases. Although an independent disease, it is also seen manifested in the form of premonitory symptom, symptom and causative factor of various disorders. 2019-20 has witnessed a new pandemic identified as Corona virus (COVID-19) with adverse health issues. In proportion to the wide variety of diseases, viral vaccines are very few, that too with adverse effects. Hence there is an urgent need of most promising Indigenous drugs with antipyretic and anti-viral activity in the current scenario. A critical analysis is made to explore the Jwarahara Yogas of classics to unfold the Antiviral, Antipyretic, Antioxidant and Immunomodulatory potential of phytochemicals in formulations. An attempt has been made to explore the antiviral and antipyretic potential of Amrutotharam Kashayam, one of the most popular and widely used Jwarahara yoga in classics. The review will definitely give new insights on the synergistic actions of phytochemicals in...
Jwara is the first and foremost among all somatic diseases. Although an independent disease, it i... more Jwara is the first and foremost among all somatic diseases. Although an independent disease, it is also seen manifested in the form of premonitory symptom, symptom and causative factor of various disorders. 2019-20 has witnessed a new pandemic identified as Corona virus (COVID-19) with adverse health issues. In proportion to the wide variety of diseases, viral vaccines are very few, that too with adverse effects. Hence there is an urgent need of most promising Indigenous drugs with antipyretic and anti-viral activity in the current scenario. A critical analysis is made to explore the Jwarahara Yogas of classics to unfold the Antiviral, Antipyretic, Antioxidant and Immunomodulatory potential of phytochemicals in formulations. An attempt has been made to explore the antiviral and antipyretic potential of Amrutotharam Kashayam, one of the most popular and widely used Jwarahara yoga in classics. The review will definitely give new insights on the synergistic actions of phytochemicals in formulations to revalidate the clinical evidences and will throw lime light on repurposing of the documented novel drugs and combinations in classics to offer unique preventive strategies and therapeutic solutions to the present pandemic and emerging viral infections.
International journal of research in ayurveda and pharmacy, 2021
Jwara is the first and foremost among all somatic diseases Although an independent disease, it is... more Jwara is the first and foremost among all somatic diseases Although an independent disease, it is also seen manifested in the form of premonitory symptom, symptom and causative factor of various disorders 2019-20 has witnessed a new pandemic identified as Corona virus (COVID-19) with adverse health issues In proportion to the wide variety of diseases, viral vaccines are very few, that too with adverse effects Hence there is an urgent need of most promising Indigenous drugs with antipyretic and anti-viral activity in the current scenario A critical analysis is made to explore the Jwarahara Yogas of classics to unfold the Antiviral, Antipyretic, Antioxidant and Immunomodulatory potential of phytochemicals in formulations An attempt has been made to explore the antiviral and antipyretic potential of Amrutotharam Kashayam, one of the most popular and widely used Jwarahara yoga in classics The review will definitely give new insights on the synergistic actions of phytochemicals in formul...
Journal of Ayurveda Medical Sciences, 2017
Introduction: Ficus religiosa Linn. (Moraceae) is a pharmacopoeial drug of Ayurveda, commonly kno... more Introduction: Ficus religiosa Linn. (Moraceae) is a pharmacopoeial drug of Ayurveda, commonly known as peepal in Hindi. This is a source drug for the plant Ashvattha in Ayurveda. The plant has a religious and ancient history found all over India. The tree is found to be sacred because of its religious rituals. It has also got the importance in medicinal science and hence used in different systems of medicine such as Ayurveda, Unani and Homeopathy. The drug is considered to be precious because of its wide therapeutic efficacy. The different parts of this plant like bark, leaves, tender shoots, fruit, seed, latex etc. are being used for different ailments since ages. Acharyas in samhita have mentioned the use of Ashvattha in various contexts. Vata rakta is one such disease where the bark kashaya of Ashvattha is used. One of the correlations for vata rakta in modern science is gout in which one of the parameters assessed is hyperurecemia. Here the pharmacological study is conducted as a preclinical study by using different experimental models. Methods: The experimental study was carried out in the Pharmacology department of SDM Centre for Research in Ayurveda and Allied Sciences, Udupi. The anti-hyperuricemic activity has been assessed by Potassium oxonate induced hyperuricemic model. Result: The experimental study had shown bark kashaya as extremely significant values in serum uric acid and urine uric acid parameters in anti-hyperuricemic activity. Conclusion: The experiment has shown Ashvattha bark to have potential antihyperuricemic activity.
IJRAP, 2021
Jwara is the first and foremost among all somatic diseases. Although an independent disease, it i... more Jwara is the first and foremost among all somatic diseases. Although an independent disease, it is also seen manifested in the form of premonitory symptom, symptom and causative factor of various disorders. 2019-20 has witnessed a new pandemic identified as Corona virus (COVID-19) with adverse health issues. In proportion to the wide variety of diseases, viral vaccines are very few, that too with adverse effects. Hence there is an urgent need of most promising Indigenous drugs with antipyretic and anti-viral activity in the current scenario. A critical analysis is made to explore the Jwarahara Yogas of classics to unfold the Antiviral, Antipyretic, Antioxidant and Immunomodulatory potential of phytochemicals in formulations. An attempt has been made to explore the antiviral and antipyretic potential of Amrutotharam Kashayam, one of the most popular and widely used Jwarahara yoga in classics. The review will definitely give new insights on the synergistic actions of phytochemicals in...