Juzer Shabbir | Liaquat college of medicine and dentistry (original) (raw)
Papers by Juzer Shabbir
Journal of Taibah University Medical Sciences
Journal of Functional Biomaterials
Application of intracanal medicaments may affect the physical properties of root dentine. Calcium... more Application of intracanal medicaments may affect the physical properties of root dentine. Calcium hydroxide (CH), a gold standard intracanal medicament, has proven to decrease root dentine microhardness. A natural extract, propolis, has been shown to be superior to CH in eradicating endodontic microbes, but its effect on the microhardness of root dentine is still not known. This investigation aims to evaluate the effect of propolis on root dentine microhardness compared to calcium hydroxide. Ninety root discs were randomly divided into three groups and treated with CH, propolis, and a control. A Vickers hardness indentation machine with a load of 200 g and dwell time of 15 s at 24 h, 3, and 7 days was used for microhardness testing. ANOVA and Tukey’s post hoc test were used for statistical analysis. A progressive decrease in microhardness values was observed in CH (p < 0.01), whereas a progressive increase was observed in the propolis group (p < 0.01). At 7 days, propolis demo...
Journal of Herbal Medicine
Journal of the Pakistan Dental Association, 2020
OBJECTIVE: To investigate the effect of nickel titanium rotary endodontic file immersion in hydro... more OBJECTIVE: To investigate the effect of nickel titanium rotary endodontic file immersion in hydrogen peroxide on cyclic fatigue resistance. METHODOLOGY: Twenty Six Protaper Universal (Dentsply Maillerfier) F1 files were randomly divided into two experimental groups. In Group I, Protaper universal variable taper F1 files were immersed in normal saline where as in Group II, the files were soaked in hydrogen peroxide (6% w/v) for 2 hours at 37°C. Cyclic fatigue of each file was checked by recording the number of rotations required to break a file in a 90°curve with a 5 mm radius. For statistical analysis of data, Two-way ANOVA was applied. A p value of <0.05 was considered significant. RESULT: Out of Twenty Six, Six files fractured spontaneously after immersion in hydrogen peroxide. Twenty files were subjected to fracture resistance testing. Statistically significant difference in cyclic fatigue resistace between the two groups was found (p=0.002). The files soaked in Group II requi...
Biomaterials in Endodontics, 2022
F1000Research, 2021
Optical coherence tomography (OCT) is a non-invasive investigative technique that is used to obta... more Optical coherence tomography (OCT) is a non-invasive investigative technique that is used to obtain high-resolution three-dimensional (3D) images of biological structures. This method is useful in diagnosing diseases of specific organs like the eye, where a direct biopsy cannot be conducted. Since its inception, significant advancements have been made in its technology. Apart from its initial application in ophthalmology for retinal imaging, substantial technological innovations in OCT brought by the research community have enabled its utilization beyond its original scope and allowed its application in many new clinical areas. This review presents a summary of the clinical applications of OCT in the field of medicine (ophthalmology, cardiology, otology, and dermatology) and dentistry (tissue imaging, detection of caries, analysis of dental polymer composite restorations, imaging of root canals, and diagnosis of oral cancer). In addition, potential advantages and disadvantages of OC...
An Illustrated Guide to Oral Histology, 2021
European Dental Research and Biomaterials Journal, 2020
Dental caries is the most prevalent disease in primary, mixed, and permanent dentition. Many prev... more Dental caries is the most prevalent disease in primary, mixed, and permanent dentition. Many preventive and treatment strategies were used in the last decades. Silver diamine fluoride (SDF) is a promising nontoxic material which proves to be a turning point concerning conservative dentistry if the patient and dental practitioners are adequately educated regarding it. Several advantages have been reported related to the use of SDF, including the procedure being pain-free and drill-free, patient- and doctor-friendly caries control strategy, and management of dentinal hypersensitivity.
International Endodontic Journal, 2020
Changes made as a result of publishing processes such as copy-editing, formatting and page number... more Changes made as a result of publishing processes such as copy-editing, formatting and page numbers may not be reflected in this version. For the definitive version of this publication, please refer to the published source. You are advised to consult the publisher's version if you wish to cite this paper.
Healthcare, 2020
The world is currently facing a pandemic crisis due to a novel coronavirus. For this purpose, acq... more The world is currently facing a pandemic crisis due to a novel coronavirus. For this purpose, acquiring updated knowledge regarding prevention and disinfection during the current pandemic is necessary for every dental practitioner. In our study, we aimed to evaluate globally the level of knowledge and the attitude of dental practitioners related to disinfection. A total of 385 participants out of 401 participants from 23 different countries across the world were included in the final analysis after the exclusion of incomplete responses. The majority of the dentists who responded were females (53.8%) and were practicing at private health institutes (36.4%). The mean knowledge score of the participants was estimated to be 4.19 ± 1.88 out of 12, reflecting insufficient knowledge, and the mean attitude score of the participants was estimated to be 12.24 ± 3.23 out of 15, which shows a positive attitude toward disinfection practices during coronavirus 2019 (COVID-19). Thus, the current s...
Pakistan Journal of Medicine and Dentistry, 2020
Background: The pulp tissue is confined within hard tissue boundaries and cannot be examined dire... more Background: The pulp tissue is confined within hard tissue boundaries and cannot be examined directly for health evaluation. Hence, its assessment is usually based on sensibility tests. Accurate diagnosis of the pulpal status requires evaluation with combination of sensibility tests. The objective of this study was to assess the mutual agreement between the electric pulp test and cold test in determining pulp vitality. Methods: Total 106 patients, aged 18 to 30 years, attending the dental OPD of Operative Dentistry/Endodontics department; Dr. Ishrat-ul-Ibad Institute of Oral Health Sciences, Karachi were selected for the study. The cold and electric pulp tests were used to determine the presence or absence of tingling sensation. Teeth were marked as vital in presence and non-vital in absence of any tingling or painful response. Agreement between these two tests was calculated using SPSS-18. To calculate the mean and standard deviation, descriptive statistics were applied for quantit...
International Journal of Environmental Research and Public Health, 2020
Propolis is a potent anti-microbial and natural anti-inflammatory by-product obtained from the be... more Propolis is a potent anti-microbial and natural anti-inflammatory by-product obtained from the beehive. Studies have demonstrated the superior biocompatibility and anti-microbial properties of propolis as compared to calcium hydroxide. However, its effect on postoperative endodontic pain is unknown. Therefore, this study aimed to investigate the impact of Chinese propolis paste as an intracanal medicament on postoperative endodontic pain intensities compared with calcium hydroxide (control) at different time intervals in necrotic teeth with periapical radiolucency. Eighty patients with single-rooted necrotic teeth with visible periapical radiolucency were recruited and randomly allocated to either the calcium hydroxide or propolis groups. After chemo-mechanical preparation and intracanal medicament insertion, patients were given the VAS (visual analogue scale) to record pain scores. Inter-group data were compared and analyzed using two-way repeated measure ANOVA (Bonferroni test). A...
Journal of the Pakistan Dental Association
OBJECTIVE: To determine and compare the frequency of endodontic emergencies (EE) with other denta... more OBJECTIVE: To determine and compare the frequency of endodontic emergencies (EE) with other dental conditions in patients attending Qamar Dental Hospital (QDH), Karachi during first wave of COVID-19 pandemic. METHODOLOGY:The dental records of all the dental patients (n= 1824) who attended the QDH during first wave of COVID-19 Pandemic peak were retrieved and divided into 3 groups based on diagnostic conditions:1) - non-emergency (NE), 2)- Emergency endodontic (EE), and 3) - Emergency non-endodontic (ENE). The age groups were also divided into 3 group of 0 to 25, 26 to 50, and >50. Categorical variables were reported as %. Chi-square test was used to find inter-group difference. p <0.05 was regarded as significant. RESULTS: Dental records of 1823/1824 patients were analysed. Results suggested that 54.6% of the patients were females and 50.1% of patients belonged to age range 0 to 25. Moreover, 1040 (57%) patients suffered with EE conditions, and 805 (77.4%) with symptomatic irr...
Several endodontic access cavity designs have been proposed in the past decade to access the root... more Several endodontic access cavity designs have been proposed in the past decade to access the root canal space in a minimally invasive manner. The rationale for this approach was derived from the assumption that preserving more tooth structure during access preparation will improving the tooth resistance to fracture and its long-term survivability. However, is this assumption valid? Also, can this approach compromise other treatment-related aspects? In this study, we classified the different endodontic access cavity preparations in anterior and posterior teeth. We also conducted a literature review using four online databases and classified the access cavity designs presented in each article according to our proposed classification. Through the literature search, we identified 49 articles that evaluated the effect of the access cavity design on eleven different treatment parameters. The majority of the studies failed to demonstrate clear benefits of the minimally invasive access desi...
The role of inflammatory mediators in dental pulp is unique. The local environment of pulp respon... more The role of inflammatory mediators in dental pulp is unique. The local environment of pulp responds to any changes in the physiology that are highly fundamental, like odontoblast cell differentiation and other secretory activity. The aim of this review is to assess the role of cathelicidins based on their capacity to heal wounds, their immunomodulatory potential, and their ability to stimulate cytokine production and stimulate immune-inflammatory response in pulp and periapex. Accessible electronic databases were searched to find studies reporting the role of cathelicidins in pulpal inflammation and regeneration published between September 2010 and September 2020. The search was performed using the following databases: Medline, Scopus, Web of Science, SciELO and PubMed. The electronic search was performed using the combination of keywords "cathelicidins" and "dental pulp inflammation". On the basis of previous studies, it can be inferred that LL-37 plays an impor...
European Journal of Dentistry
Objectives The current study aimed to assess the impact of factors such as age, gender, and the t... more Objectives The current study aimed to assess the impact of factors such as age, gender, and the tooth type on postoperative endodontic pain in necrotic teeth with symptomatic periapical periodontitis and radiolucency dressed randomly with either calcium hydroxide or propolis paste. Materials and Methods The standard chemomechanical root canal preparation of 80 teeth was performed by the primary investigator. The intracanal medicaments were inserted by the secondary operator. Patients self-recorded their postoperative endodontic pain intensity with the help of visual analog scale at 4, 12, 24 (day 2), 48 (day 3), and 72 (day 4) hours. During analysis, patients (68/80) were grouped according to gender, age, and the tooth type. Statistical Analysis Mann–Whitney’s U test was applied for mean pain score comparison between genders and between tooth type. Kruskal–Wallis’ test was applied for mean pain score comparison between the age groups. Results No significant difference (p > 0.05) ...
European Journal of Dentistry
Objective The removal of residual pulpal debris (RPD) from the root canal walls, especially in ne... more Objective The removal of residual pulpal debris (RPD) from the root canal walls, especially in necrotic teeth is important for successful endodontic outcome. The aim of this study was to evaluate the RPD removal efficacy of handpiece mounted continuous irrigation with simultaneous root canal preparation from the apical third of root canals as compared to conventional syringe irrigation (SI). Materials and Methods Ninety extracted teeth were randomly divided into three groups: SI; handpiece mounted continuous irrigation (CI); and both syringe and continuous irrigation (CI+SI). After root canal preparation, roots were sectioned at 1 (a), 3 (b) and 5 (c) mm from apex and prepared for Hematoxylin-Eosin staining. Sections were microscopically examined for presence of RPD. Statistical Analysis Intergroup difference in average percentage of RPD at different root levels was calculated by using analysis of variance test (ANOVA). Tuckey test was used for pairwise comparison. Results ANOVA sho...
International Endodontic Journal, 2020
Azim AA, Shabbir J, Khurshid Z, Zafar MS, Ghabbani HM, Dummer PMH. Clinical endodontic management... more Azim AA, Shabbir J, Khurshid Z, Zafar MS, Ghabbani HM, Dummer PMH. Clinical endodontic management during the COVID-19 pandemic: a literature review and clinical recommendations. International Endodontic Journal.
Propolis is a potent anti-microbial and natural anti-inflammatory by-product obtained from the be... more Propolis is a potent anti-microbial and natural anti-inflammatory by-product obtained from the beehive. Studies have demonstrated the superior biocompatibility and anti-microbial properties of propolis as compared to calcium hydroxide. However, its effect on postoperative endodontic pain is unknown. Therefore, this study aimed to investigate the impact of Chinese propolis paste as an intracanal medicament on postoperative endodontic pain intensities compared with calcium hydroxide (control) at different time intervals in necrotic teeth with periapical radiolucency. Eighty patients with single-rooted necrotic teeth with visible periapical radiolucency were recruited and randomly allocated to either the calcium hydroxide or propolis groups. After chemo-mechanical preparation and intracanal medicament insertion, patients were given the VAS (visual analogue scale) to record pain scores. Inter-group data were compared and analyzed using two-way repeated measure ANOVA (Bonferroni test). A p-value of < 0.025 was considered significant. In total, >78% of the patients experienced no or only mild post-operative pain in both the groups at all time intervals, without any significant difference in pain scores between the two groups (p > 0.025). An overall flare-up rate of 14.8% was found. The results suggest that either of these medicaments can be used as an inter-appointment medication for the prevention of postoperative pain in necrotic cases.
Journal of Taibah University Medical Sciences
Journal of Functional Biomaterials
Application of intracanal medicaments may affect the physical properties of root dentine. Calcium... more Application of intracanal medicaments may affect the physical properties of root dentine. Calcium hydroxide (CH), a gold standard intracanal medicament, has proven to decrease root dentine microhardness. A natural extract, propolis, has been shown to be superior to CH in eradicating endodontic microbes, but its effect on the microhardness of root dentine is still not known. This investigation aims to evaluate the effect of propolis on root dentine microhardness compared to calcium hydroxide. Ninety root discs were randomly divided into three groups and treated with CH, propolis, and a control. A Vickers hardness indentation machine with a load of 200 g and dwell time of 15 s at 24 h, 3, and 7 days was used for microhardness testing. ANOVA and Tukey’s post hoc test were used for statistical analysis. A progressive decrease in microhardness values was observed in CH (p < 0.01), whereas a progressive increase was observed in the propolis group (p < 0.01). At 7 days, propolis demo...
Journal of Herbal Medicine
Journal of the Pakistan Dental Association, 2020
OBJECTIVE: To investigate the effect of nickel titanium rotary endodontic file immersion in hydro... more OBJECTIVE: To investigate the effect of nickel titanium rotary endodontic file immersion in hydrogen peroxide on cyclic fatigue resistance. METHODOLOGY: Twenty Six Protaper Universal (Dentsply Maillerfier) F1 files were randomly divided into two experimental groups. In Group I, Protaper universal variable taper F1 files were immersed in normal saline where as in Group II, the files were soaked in hydrogen peroxide (6% w/v) for 2 hours at 37°C. Cyclic fatigue of each file was checked by recording the number of rotations required to break a file in a 90°curve with a 5 mm radius. For statistical analysis of data, Two-way ANOVA was applied. A p value of <0.05 was considered significant. RESULT: Out of Twenty Six, Six files fractured spontaneously after immersion in hydrogen peroxide. Twenty files were subjected to fracture resistance testing. Statistically significant difference in cyclic fatigue resistace between the two groups was found (p=0.002). The files soaked in Group II requi...
Biomaterials in Endodontics, 2022
F1000Research, 2021
Optical coherence tomography (OCT) is a non-invasive investigative technique that is used to obta... more Optical coherence tomography (OCT) is a non-invasive investigative technique that is used to obtain high-resolution three-dimensional (3D) images of biological structures. This method is useful in diagnosing diseases of specific organs like the eye, where a direct biopsy cannot be conducted. Since its inception, significant advancements have been made in its technology. Apart from its initial application in ophthalmology for retinal imaging, substantial technological innovations in OCT brought by the research community have enabled its utilization beyond its original scope and allowed its application in many new clinical areas. This review presents a summary of the clinical applications of OCT in the field of medicine (ophthalmology, cardiology, otology, and dermatology) and dentistry (tissue imaging, detection of caries, analysis of dental polymer composite restorations, imaging of root canals, and diagnosis of oral cancer). In addition, potential advantages and disadvantages of OC...
An Illustrated Guide to Oral Histology, 2021
European Dental Research and Biomaterials Journal, 2020
Dental caries is the most prevalent disease in primary, mixed, and permanent dentition. Many prev... more Dental caries is the most prevalent disease in primary, mixed, and permanent dentition. Many preventive and treatment strategies were used in the last decades. Silver diamine fluoride (SDF) is a promising nontoxic material which proves to be a turning point concerning conservative dentistry if the patient and dental practitioners are adequately educated regarding it. Several advantages have been reported related to the use of SDF, including the procedure being pain-free and drill-free, patient- and doctor-friendly caries control strategy, and management of dentinal hypersensitivity.
International Endodontic Journal, 2020
Changes made as a result of publishing processes such as copy-editing, formatting and page number... more Changes made as a result of publishing processes such as copy-editing, formatting and page numbers may not be reflected in this version. For the definitive version of this publication, please refer to the published source. You are advised to consult the publisher's version if you wish to cite this paper.
Healthcare, 2020
The world is currently facing a pandemic crisis due to a novel coronavirus. For this purpose, acq... more The world is currently facing a pandemic crisis due to a novel coronavirus. For this purpose, acquiring updated knowledge regarding prevention and disinfection during the current pandemic is necessary for every dental practitioner. In our study, we aimed to evaluate globally the level of knowledge and the attitude of dental practitioners related to disinfection. A total of 385 participants out of 401 participants from 23 different countries across the world were included in the final analysis after the exclusion of incomplete responses. The majority of the dentists who responded were females (53.8%) and were practicing at private health institutes (36.4%). The mean knowledge score of the participants was estimated to be 4.19 ± 1.88 out of 12, reflecting insufficient knowledge, and the mean attitude score of the participants was estimated to be 12.24 ± 3.23 out of 15, which shows a positive attitude toward disinfection practices during coronavirus 2019 (COVID-19). Thus, the current s...
Pakistan Journal of Medicine and Dentistry, 2020
Background: The pulp tissue is confined within hard tissue boundaries and cannot be examined dire... more Background: The pulp tissue is confined within hard tissue boundaries and cannot be examined directly for health evaluation. Hence, its assessment is usually based on sensibility tests. Accurate diagnosis of the pulpal status requires evaluation with combination of sensibility tests. The objective of this study was to assess the mutual agreement between the electric pulp test and cold test in determining pulp vitality. Methods: Total 106 patients, aged 18 to 30 years, attending the dental OPD of Operative Dentistry/Endodontics department; Dr. Ishrat-ul-Ibad Institute of Oral Health Sciences, Karachi were selected for the study. The cold and electric pulp tests were used to determine the presence or absence of tingling sensation. Teeth were marked as vital in presence and non-vital in absence of any tingling or painful response. Agreement between these two tests was calculated using SPSS-18. To calculate the mean and standard deviation, descriptive statistics were applied for quantit...
International Journal of Environmental Research and Public Health, 2020
Propolis is a potent anti-microbial and natural anti-inflammatory by-product obtained from the be... more Propolis is a potent anti-microbial and natural anti-inflammatory by-product obtained from the beehive. Studies have demonstrated the superior biocompatibility and anti-microbial properties of propolis as compared to calcium hydroxide. However, its effect on postoperative endodontic pain is unknown. Therefore, this study aimed to investigate the impact of Chinese propolis paste as an intracanal medicament on postoperative endodontic pain intensities compared with calcium hydroxide (control) at different time intervals in necrotic teeth with periapical radiolucency. Eighty patients with single-rooted necrotic teeth with visible periapical radiolucency were recruited and randomly allocated to either the calcium hydroxide or propolis groups. After chemo-mechanical preparation and intracanal medicament insertion, patients were given the VAS (visual analogue scale) to record pain scores. Inter-group data were compared and analyzed using two-way repeated measure ANOVA (Bonferroni test). A...
Journal of the Pakistan Dental Association
OBJECTIVE: To determine and compare the frequency of endodontic emergencies (EE) with other denta... more OBJECTIVE: To determine and compare the frequency of endodontic emergencies (EE) with other dental conditions in patients attending Qamar Dental Hospital (QDH), Karachi during first wave of COVID-19 pandemic. METHODOLOGY:The dental records of all the dental patients (n= 1824) who attended the QDH during first wave of COVID-19 Pandemic peak were retrieved and divided into 3 groups based on diagnostic conditions:1) - non-emergency (NE), 2)- Emergency endodontic (EE), and 3) - Emergency non-endodontic (ENE). The age groups were also divided into 3 group of 0 to 25, 26 to 50, and >50. Categorical variables were reported as %. Chi-square test was used to find inter-group difference. p <0.05 was regarded as significant. RESULTS: Dental records of 1823/1824 patients were analysed. Results suggested that 54.6% of the patients were females and 50.1% of patients belonged to age range 0 to 25. Moreover, 1040 (57%) patients suffered with EE conditions, and 805 (77.4%) with symptomatic irr...
Several endodontic access cavity designs have been proposed in the past decade to access the root... more Several endodontic access cavity designs have been proposed in the past decade to access the root canal space in a minimally invasive manner. The rationale for this approach was derived from the assumption that preserving more tooth structure during access preparation will improving the tooth resistance to fracture and its long-term survivability. However, is this assumption valid? Also, can this approach compromise other treatment-related aspects? In this study, we classified the different endodontic access cavity preparations in anterior and posterior teeth. We also conducted a literature review using four online databases and classified the access cavity designs presented in each article according to our proposed classification. Through the literature search, we identified 49 articles that evaluated the effect of the access cavity design on eleven different treatment parameters. The majority of the studies failed to demonstrate clear benefits of the minimally invasive access desi...
The role of inflammatory mediators in dental pulp is unique. The local environment of pulp respon... more The role of inflammatory mediators in dental pulp is unique. The local environment of pulp responds to any changes in the physiology that are highly fundamental, like odontoblast cell differentiation and other secretory activity. The aim of this review is to assess the role of cathelicidins based on their capacity to heal wounds, their immunomodulatory potential, and their ability to stimulate cytokine production and stimulate immune-inflammatory response in pulp and periapex. Accessible electronic databases were searched to find studies reporting the role of cathelicidins in pulpal inflammation and regeneration published between September 2010 and September 2020. The search was performed using the following databases: Medline, Scopus, Web of Science, SciELO and PubMed. The electronic search was performed using the combination of keywords "cathelicidins" and "dental pulp inflammation". On the basis of previous studies, it can be inferred that LL-37 plays an impor...
European Journal of Dentistry
Objectives The current study aimed to assess the impact of factors such as age, gender, and the t... more Objectives The current study aimed to assess the impact of factors such as age, gender, and the tooth type on postoperative endodontic pain in necrotic teeth with symptomatic periapical periodontitis and radiolucency dressed randomly with either calcium hydroxide or propolis paste. Materials and Methods The standard chemomechanical root canal preparation of 80 teeth was performed by the primary investigator. The intracanal medicaments were inserted by the secondary operator. Patients self-recorded their postoperative endodontic pain intensity with the help of visual analog scale at 4, 12, 24 (day 2), 48 (day 3), and 72 (day 4) hours. During analysis, patients (68/80) were grouped according to gender, age, and the tooth type. Statistical Analysis Mann–Whitney’s U test was applied for mean pain score comparison between genders and between tooth type. Kruskal–Wallis’ test was applied for mean pain score comparison between the age groups. Results No significant difference (p > 0.05) ...
European Journal of Dentistry
Objective The removal of residual pulpal debris (RPD) from the root canal walls, especially in ne... more Objective The removal of residual pulpal debris (RPD) from the root canal walls, especially in necrotic teeth is important for successful endodontic outcome. The aim of this study was to evaluate the RPD removal efficacy of handpiece mounted continuous irrigation with simultaneous root canal preparation from the apical third of root canals as compared to conventional syringe irrigation (SI). Materials and Methods Ninety extracted teeth were randomly divided into three groups: SI; handpiece mounted continuous irrigation (CI); and both syringe and continuous irrigation (CI+SI). After root canal preparation, roots were sectioned at 1 (a), 3 (b) and 5 (c) mm from apex and prepared for Hematoxylin-Eosin staining. Sections were microscopically examined for presence of RPD. Statistical Analysis Intergroup difference in average percentage of RPD at different root levels was calculated by using analysis of variance test (ANOVA). Tuckey test was used for pairwise comparison. Results ANOVA sho...
International Endodontic Journal, 2020
Azim AA, Shabbir J, Khurshid Z, Zafar MS, Ghabbani HM, Dummer PMH. Clinical endodontic management... more Azim AA, Shabbir J, Khurshid Z, Zafar MS, Ghabbani HM, Dummer PMH. Clinical endodontic management during the COVID-19 pandemic: a literature review and clinical recommendations. International Endodontic Journal.
Propolis is a potent anti-microbial and natural anti-inflammatory by-product obtained from the be... more Propolis is a potent anti-microbial and natural anti-inflammatory by-product obtained from the beehive. Studies have demonstrated the superior biocompatibility and anti-microbial properties of propolis as compared to calcium hydroxide. However, its effect on postoperative endodontic pain is unknown. Therefore, this study aimed to investigate the impact of Chinese propolis paste as an intracanal medicament on postoperative endodontic pain intensities compared with calcium hydroxide (control) at different time intervals in necrotic teeth with periapical radiolucency. Eighty patients with single-rooted necrotic teeth with visible periapical radiolucency were recruited and randomly allocated to either the calcium hydroxide or propolis groups. After chemo-mechanical preparation and intracanal medicament insertion, patients were given the VAS (visual analogue scale) to record pain scores. Inter-group data were compared and analyzed using two-way repeated measure ANOVA (Bonferroni test). A p-value of < 0.025 was considered significant. In total, >78% of the patients experienced no or only mild post-operative pain in both the groups at all time intervals, without any significant difference in pain scores between the two groups (p > 0.025). An overall flare-up rate of 14.8% was found. The results suggest that either of these medicaments can be used as an inter-appointment medication for the prevention of postoperative pain in necrotic cases.