Wayne Fletcher | University of Leeds (original) (raw)
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Papers by Wayne Fletcher
Drug and Alcohol Dependence, 2009
Individuals with substance abuse problems who are involved in the criminal justice system frequen... more Individuals with substance abuse problems who are involved in the criminal justice system frequently need community-based drug and alcohol abuse treatment and other services. To reduce the risk of relapse to illicit drugs and criminal recidivism, criminal justice agencies may need to establish collaborations with substance abuse treatment and other community-based service providers. Although there are many variations of interorganizational relationships, the nature of these interagency collaborations among justice agencies and treatment providers has received little systematic study. As a first step, we present an instrument to measure interagency collaboration and integration activities using items in the National Criminal Justice Treatment Practices Surveys conducted as part of the Criminal Justice Drug Abuse Treatment Studies (CJ-DATS). Collaboration and integration activities related to drug-involved offenders were examined between substance abuse treatment providers, correctional agencies, and the judiciary. The measurement scale reliably identified two levels of collaboration: less structured, informal networking and coordination and more structured and formalized levels of cooperation and collaboration. An illustration of the use of the systems integration tool is presented.
Human Molecular Genetics, 1999
Mouse genetic models for common human diseases have been studied for most of the 20th century. Al... more Mouse genetic models for common human diseases have been studied for most of the 20th century. Although many polygenic strain differences and spontaneous single gene mutants have been extensively characterized over the years, knowing their innermost secrets ultimately requires the identity of the mutated genes. One group of neurological mutants, detected initially due to cerebellar dysfunction, was identified as models for epilepsy when they were unexpectedly found to have spike-wave seizures associated with behavioral arrest, a central feature of absence or petit-mal epilepsy. A further surprise was that recently identified defective genes encode different subunits of voltage-gated Ca 2+ channels (VGCCs), implying common seizure mechanisms. In this review we first consider these spontaneous mutants with VGCC defects in the context of other mouse models for epilepsy. Then, from the new wave of genetic and functional studies of these mutants we discuss their prospects for yielding insight into the molecular mechanisms of epilepsy.
Psychology & Health, 1999
The relationship between self-reports of daily hassles and number of between-meal snacks consumed... more The relationship between self-reports of daily hassles and number of between-meal snacks consumed and the effect of moderating variables was investigated in a sample of 60 students. Respondents completed daily diaries for a period of 7 consecutive days reporting number and severity of daily hassles and number of snacks consumed. Questionnaire measures of emotional, external and restrained eating and gender wm also taken. Number of hassles was significantly correlated with number of snacks consumed (r = 0.312. p < 0.001). This relationship was moderated by an individual difference variable. external eating: those high on external eating show significant positive relationship between hassles and snacking, while those low on external eating show no significant relationship. We found no support for the role of average severity of hassle, emotional eating. restrained eating or gender as moderators of the hassles-snacks relationship. The results suggest the need to consider external eating in examining stress-eating relationships.
Drug and Alcohol Dependence, 2009
Individuals with substance abuse problems who are involved in the criminal justice system frequen... more Individuals with substance abuse problems who are involved in the criminal justice system frequently need community-based drug and alcohol abuse treatment and other services. To reduce the risk of relapse to illicit drugs and criminal recidivism, criminal justice agencies may need to establish collaborations with substance abuse treatment and other community-based service providers. Although there are many variations of interorganizational relationships, the nature of these interagency collaborations among justice agencies and treatment providers has received little systematic study. As a first step, we present an instrument to measure interagency collaboration and integration activities using items in the National Criminal Justice Treatment Practices Surveys conducted as part of the Criminal Justice Drug Abuse Treatment Studies (CJ-DATS). Collaboration and integration activities related to drug-involved offenders were examined between substance abuse treatment providers, correctional agencies, and the judiciary. The measurement scale reliably identified two levels of collaboration: less structured, informal networking and coordination and more structured and formalized levels of cooperation and collaboration. An illustration of the use of the systems integration tool is presented.
Human Molecular Genetics, 1999
Mouse genetic models for common human diseases have been studied for most of the 20th century. Al... more Mouse genetic models for common human diseases have been studied for most of the 20th century. Although many polygenic strain differences and spontaneous single gene mutants have been extensively characterized over the years, knowing their innermost secrets ultimately requires the identity of the mutated genes. One group of neurological mutants, detected initially due to cerebellar dysfunction, was identified as models for epilepsy when they were unexpectedly found to have spike-wave seizures associated with behavioral arrest, a central feature of absence or petit-mal epilepsy. A further surprise was that recently identified defective genes encode different subunits of voltage-gated Ca 2+ channels (VGCCs), implying common seizure mechanisms. In this review we first consider these spontaneous mutants with VGCC defects in the context of other mouse models for epilepsy. Then, from the new wave of genetic and functional studies of these mutants we discuss their prospects for yielding insight into the molecular mechanisms of epilepsy.
Psychology & Health, 1999
The relationship between self-reports of daily hassles and number of between-meal snacks consumed... more The relationship between self-reports of daily hassles and number of between-meal snacks consumed and the effect of moderating variables was investigated in a sample of 60 students. Respondents completed daily diaries for a period of 7 consecutive days reporting number and severity of daily hassles and number of snacks consumed. Questionnaire measures of emotional, external and restrained eating and gender wm also taken. Number of hassles was significantly correlated with number of snacks consumed (r = 0.312. p < 0.001). This relationship was moderated by an individual difference variable. external eating: those high on external eating show significant positive relationship between hassles and snacking, while those low on external eating show no significant relationship. We found no support for the role of average severity of hassle, emotional eating. restrained eating or gender as moderators of the hassles-snacks relationship. The results suggest the need to consider external eating in examining stress-eating relationships.