The influence of sex, age, and handedness on corpus callosum morphology: A meta-analysis (original) (raw)

References

• Aboitz, F., Scheibel, A. B., Fisher, R. S., & Zaidel, E. (1992). Fiber composition of the human corpus callosum. Brain Research, 598, 143–153.
  Article Google Scholar
• Aboitz, F., Scheibel, A. B., & Zaidel, E. (1992). Morphometry of the Sylvian fissure and the corpus callosum with emphasis on sex differences. Brain, 115, 1521–1541.
  Article Google Scholar
• Allen, L. S., Richey, M. F., Chai, Y. M., & Gorski, R. A. (1991). Sex differences in the corpus callosum of the living human being. Journal of Neuroscience, 11, 933–942.
  PubMed Google Scholar
• Annett, M. (1972). The distribution of manual asymmetry. British Journal of Psychology, 63, 343–358.
  Article PubMed Google Scholar
• Ansari, K. A., & Loch, J. (1975). Decreased myelin basic protein content of the aged human brain. Neurology, 25, 1045–1050.
  Article PubMed Google Scholar
• Bean, R. B. (1906). Some racial peculiarities of the Negro brain. American Journal of Anatomy, 5, 353–432.
  Article Google Scholar
• Bryden, M. P. (1982). Laterality: Functional asymmetry in the intact brain. New York: Academic Press.
  Google Scholar
• Clarke, J. M., & Zaidel, E. (1994). Anatomical-behavioral relationships: Corpus callosum morphometry and hemispheric specialization. Behavioural Brain Research, 64, 195–202.
  Article Google Scholar
• Clarke, S., Kraftsik, R., Van der Loos, H., & Innocenti, G. (1989). Forms and measures of adult and developing human corpus callosum: Is there sexual dimorphism? Journal of Comparative Neurology, 280, 213–230.
  Article PubMed Google Scholar
• Cohen, J. (1977). Statistical power for the behavioral sciences. New York: Academic Press.
  Google Scholar
• Cohen, J., & Cohen, P. (1983). Applied multiple regression for the behavioral sciences (2nd ed.). Hillsdale, NJ: Erlbaum.
  Google Scholar
• De Lacoste-Utamsing, C., & Holloway, R. L. (1982, June 25). Sexual dimorphism in the human corpus callosum. Science, 216, 1431–1432.
  Article Google Scholar
• Dennis, M. (1976). Impaired sensory and motor differentiation with corpus callosum agenesis: A lack of callosal inhibition during ontogeny? Neuropsychologia, 14, 455–469.
  Article PubMed Google Scholar
• Glass, G. V., McGaw, B., & Smith, M. L. (1981). Meta-analysis in social research. Newbury Park, CA: Sage.
  Google Scholar
• Hauser, P., Dauphinais, I. D., Berrettini, W., DeLisi, L. E., Gelernter, J., & Post, R. M. (1989). Corpus callosum dimensions measured by magnetic resonance imaging in bipolar affective disorder and schizophrenia. Biological Psychiatry, 26, 659–668.
  Article PubMed Google Scholar
• Hedges, L. V., & Olkin, I. (1985). Statistical methods for meta-analysis. Orlando, FL: Academic Press.
  Google Scholar
• Hellige, J. B. (1993). Hemispheric asymmetry: What’s right and what’s left. Cambridge, MA: Harvard University Press.
  Google Scholar
• Holloway, R. L., & De Lacoste, C. (1986). Sexual dimorphism in the human corpus callosum: An extension and replication study. Human Neurobiology, 5, 87–91.
  PubMed Google Scholar
• Juraska, J. M., & Kopcik, J. R. (1988). Sex and environmental influences on the size and ultrastructure of the rat corpus callosum. Brain Research, 450, 1–8.
  Article PubMed Google Scholar
• Kemper, T. L. (1994). Neuroanatomical and neuropathological changes during aging and in dementia. In M. L. Albert & E. J. E. Knoepfel (Eds.), Clinical neurology of aging (2nd ed., pp. 3–67). New York: Oxford University Press.
  Google Scholar
• Kimura, D. (1987). Are men’s and women’s brains really different? Canadian Psychology, 28, 133–147.
  Article Google Scholar
• Kinsbourne, M. (1982). Hemispheric specialization and the growth of human understanding. American Psychologist, 37, 411–420.
  Article PubMed Google Scholar
• Kirkpatrick, J. B., & Hyman, L. A. (1987). White-matter lesions in MR imaging of clinically healthy brains of elderly subjects: Possible pathological basis. Radiology, 162, 509–511.
  PubMed Google Scholar
• LaMantia, A. S., & Rakic, P. (1990). Cytological and quantitative characteristics of four cerebral commissures in the rhesus monkey. Journal of Comparative Neurology, 291, 520–537.
  Article PubMed Google Scholar
• Mall, F. P. (1909). On several anatomical characters of the human brain said to vary according to race and sex, with special reference to the frontal lobes. American Journal of Anatomy, 9, 1–32.
  Article Google Scholar
• Mathew, R. J., Partain, C. L., Prakash, R., Kulkarni, M. V., Logan, T. P., & Wilson, W. H. (1985). A study of the septum pellucidum and corpus callosum in schizophrenia with MR imaging. Acta Psychiatrica Scandinavica, 72, 414–421.
  Article PubMed Google Scholar
• McGlone, J. (1980). Sex differences in human brain asymmetry: A critical survey. Behavioral Brain Science, 3, 215–263.
  Article Google Scholar
• Pandya, D. N., & Seltzer, B. (1986). The topography of commissural fibers. In F. Lepore, M. Ptito, & H. H. Jasper (Eds.), Two hemispheres—One brain: Functions of the corpus callosum (pp. 47–73). New York: Alan R. Liss.
  Google Scholar
• Peters, M. (1988). The size of the corpus callosum in males and females: Implications of a lack of allometry. Canadian Journal of Psychology, 42, 313–324.
  Article PubMed Google Scholar
• Raz, N. (in press). Neuroanatomy of aging brain: Evidence from structural MRI. In E. D. Bigler (Ed.), Handbook of human brain function: Neuroimaging. San Diego, CA: Academic Press.
• Raz, N., Spencer, W., Torres, I. T., & Acker, J. D. (1990). Sex and age-related differences in midsaggital areas of the cerebral cortex and corpus callosum: An MRI investigation. Society for Neuroscience Abstracts, 16, 1160.
  Google Scholar
• Steinmetz, H., Jancke, L., Kleinschmidt, A., Schlaug, G., Volkmann, J., & Huang, Y. (1992). Sex but no hand differences in the isthmus of the corpus callosum. Neurology, 42, 749–752.
  Article PubMed Google Scholar
• Tukey, J. W. (1977). Exploratory data analysis. Reading, MA: Addison-Wesley.
  Google Scholar
• Uematsu, M., & Kaiya, H. (1988). The morphology of the corpus callosum in schizophrenia: An MRI study. Schizophrenia Research, 1, 391–398.
  Article PubMed Google Scholar
• Witelson, S. F. (1985, August 16). The brain connection: The corpus callosum is larger in left-handers. Science, 229, 665–668.
  Article PubMed Google Scholar
• Witelson, S. F. (1989). Hand and sex differences in the isthmus and genu of the human corpus callosum: A postmortem morphological study. Brain, 112, 799–835.
  Article PubMed Google Scholar
• Witelson, S. F. (1992). Cognitive neuroanatomy: A new era. Neurology, 42, 709–713.
  Article PubMed Google Scholar
• Woodruff, P. W., Pearlson, G. D., Geer, M. J., Barta, P. E., & Chilcoat, H. D. (1993). A computerized magnetic resonance imaging study of corpus callosum morphology in schizophrenia. Psychological Medicine, 23, 45–56.
  Article PubMed Google Scholar
• Zaidel, E., Clarke, J. M., & Suyenobu, B. (1990). Hemispheric independence: A paradigm case for cognitive neuroscience. In A. B. Scheibel & A. F. Wechsler (Eds.), Neurobiology of higher cognitive functions (pp. 297–355). New York: Guilford.
  Google Scholar

Studies Included in Meta-Analysis

• Aboitz, F., Scheibel, A. B., & Zaidel, E. (1992). Morphometry of the Sylvian fissure and the corpus callosum with emphasis on sex differences. Brain, 115, 1521–1541.
  Article Google Scholar
• Allen, L. S., Richey, M. F., Chai, Y. M., & Gorski, R. A. (1991). Sex differences in the corpus callosum of the living human being. Journal of Neuroscience, 11, 933–942.
  PubMed Google Scholar
• Bean, R. B. (1906). Some racial peculiarities of the Negro brain. American Journal of Anatomy, 5, 353–432.
  Article Google Scholar
• Burke, H. L., & Yeo, R. A. (1994). Systematic variations in callosal morphology: The effects of age, gender, hand preference and anatomic asymmetry. Neuropsychology, 8, 563–571.
  Article Google Scholar
• Byne, W., Bleier, R., & Houston, L. (1988). Variations in human corpus callosum do not predict gender: A study using magnetic resonance imaging. Behavioral Neuroscience, 102, 222–227.
  Article PubMed Google Scholar
• Clarke, J. M., & Zaidel, E. (1994). Anatomical-behavioral relationships: Corpus callosum morphometry and hemispheric specialization. Behavioural Brain Research, 64, 195–202.
  Article Google Scholar
• Clarke, S., Kraftsik, R., Van der Loos, H., & Innocenti, G. (1989). Forms and measures of adult and developing human corpus callosum: Is there sexual dimorphism? Journal of Comparative Neurology, 280, 213–230.
  Article PubMed Google Scholar
• De Lacoste, M. C., Adesanya, T., & Woodward, D. J. (1990). Measures of gender differences in the human brain and their relationship to brain weight. Biological Psychiatry, 28, 931–942.
  Article PubMed Google Scholar
• De Lacoste-Utamsing, C., & Holloway, R. L. (1982, June 25). Sexual dimorphism in the human corpus callosum. Science, 216, 1431–1432.
  Article Google Scholar
• Demeter, S., Ringo, J. L., & Doty, R. W. (1988). Morphometric analysis of the human corpus callosum and anterior commissure. Human Neurobiology, 6, 219–226.
  PubMed Google Scholar
• Doraiswamy, P. M., Figiel, G. S., Husain, M. M., McDonald, W. M., Shah, S. A., Boyko, O. B., Ellinwood, E. H., & Krishnan, K. R. (1991). Aging of the human corpus callosum: Magnetic resonance imaging in normal volunteers. Journal of Neuropsychiatry & Clinical Neurosciences, 3, 392–397.
  Google Scholar
• Duara, R., Kushch, A., Gross-Glenn, K., Barker, W. W., Jallad, B., Pascal, S., Lowenstein, D.A., Sheldon, J., Rabin, M., Levin, B., & Lubs, H. (1991). Neuroanatomic differences between dyslexic and normal readers on magnetic resonance imaging scans. Archives of Neurology, 48, 410–416.
  Article PubMed Google Scholar
• Elster, A. D., DiPersio, D. A., & Moody, D. M. (1990). Sexual dimorphism of the human corpus callosum studied by magnetic resonance imaging: Fact, fallacy and statistical confidence. Brain Development, 12, 321–325.
  Article PubMed Google Scholar
• Emory, L. E., Williams, D. H., Cole, C. M., Amparo, E. G., & Meyer, W. J. (1991). Anatomic variation of the corpus callosum in persons with gender dysphoria. Archives of Sexual Behavior, 20, 409–417.
  Article PubMed Google Scholar
• Going, J. J., & Dixson, A. (1990). Morphometry of the adult human corpus callosum: Lack of sexual dimorphism. Journal of Anatomy, 171, 163–167.
  PubMed Google Scholar
• Gunther, W., Petsch, R., Steinberg, R., Moser, E., Streck, P., Heller, H., Kurtz, G., & Hippius, H. (1991). Brain dysfunction during motor activation and corpus callosum alterations in schizophrenia measured by cerebral blood flow and magnetic resonance imaging. Biological Psychiatry, 29, 535–555.
  Article PubMed Google Scholar
• Habib, M., Gayraud, D., Olivia, A., Regis, J., Salamon, G., & Khalil, R. (1991). Effects of handedness and sex on the morphology of the corpus callosum: A study with brain magnetic resonance imaging. Brain & Cognition, 16, 41–61.
  Article Google Scholar
• Hauser, P., Dauphinais, I. D., Berrettini, W., DeLisi, L. E., Gelernter, J., & Post, R. M. (1989). Corpus callosum dimensions measured by magnetic resonance imaging in bipolar affective disorder and schizophrenia. Biological Psychiatry, 26, 659–668.
  Article PubMed Google Scholar
• Hayakawa, K., Konishi, Y., Matsuda, T., Kuriyama, M., Konishi, K., Yamashita, K., Okumura, R., & Hamanaka, D. (1989). Development and aging of brain midline structures: Assessment with MR imaging. Radiology, 172, 171–177.
  PubMed Google Scholar
• Kertesz, A., Polk, M., Howell, T., & Black, S. E. (1987). Cerebral dominance, sex and callosal size in MRI. Neurology, 37, 1385–1388.
  Article PubMed Google Scholar
• Laissy, J. P., Patrux, B., Duchateau, C., Hannequin, D., Hugonet, P., Ait-Yahia, H., & Thiebot, J. (1993). Midsaggital MR measurements of the corpus callosum in healthy subjects and diseased patients: A prospective survey. American Journal of Neuroradiology, 14, 145–154.
  PubMed Google Scholar
• Lewine, R. R. J., Gulley, L. R., Risch, S. C., Jewart, R., & Houpt, J. L. (1990). Sexual dimorphism, brain morphology and schizophrenia. Schizophrenia Bulletin, 16, 195–203.
  Article PubMed Google Scholar
• Mall, F. P. (1909). On several anatomical characters of the human brain said to vary according to race and sex, with special reference to the frontal lobes. American Journal of Anatomy, 9, 1–32.
  Article Google Scholar
• Mathew, R. J., Partain, C. L., Prakash, R., Kulkarni, M. V., Logan, T. P., & Wilson, W. H. (1985). A study of the septum pellucidum and corpus callosum in schizophrenia with MR imaging. Acta Psychiatrica Scandinavica, 72, 414–421.
  Article PubMed Google Scholar
• Nasrallah, H. A., Andreassen, N. C., Coffman, J. A., Olson, S. C., Dunn, V. D., Erhardt, J. C., & Chapman, S. M. (1986). A controlled magnetic resonance imaging study of corpus callosum thickness in schizophrenia. Biological Psychiatry, 21, 274–282.
  Article PubMed Google Scholar
• Okamoto, K., Ito, J., & Tokiguchi, S. (1990). The MR findings of the corpus callosum in normal young volunteers. Nippon Igaku Hoshasen Gakkai Zasshi, 50, 954–963.
  PubMed Google Scholar
• O’Kusky, J., Strauss, E., Kosaka, B., Wada, J., Li, D., Druhan, M., & Petrie, J. (1988). The corpus callosum is larger with right-hemisphere cerebral speech dominance. Annals of Neurology, 24, 379–383.
  Article PubMed Google Scholar
• Raine, A., Harrison, G. N., Reynolds, G. P., Sheard, C., Cooper, E., & Medley, I. (1990). Structural and functional characteristics of the corpus callosum in schizophrenics, psychiatric controls, and normal controls. Archives of General Psychiatry, 47, 1060–1064.
  Article PubMed Google Scholar
• Raz, N. (1994). [Age-related differences in human corpus callosum]. Unpublished raw data.
• Raz, N., Spencer, W., Torres, I. T., & Acker, J. D. (1990). Sex and age-related differences in midsaggital areas of the cerebral cortex and corpus callosum: An MRI investigation. Society for Neuroscience Abstracts, 16, 1160.
  Google Scholar
• Simon, J. H., Schiffer, R. B., Rudick, R. A., & Herndon, R. M. (1987). Quantitative determination of MS-induced corpus callosum atrophy in vivo using MRI imaging. American Journal of Neuroradiology, 8, 599–604.
  PubMed Google Scholar
• Steinmetz, H., Jancke, L., Kleinschmidt, A., Schlaug, G., Volkmann, J., & Huang, Y. (1992). Sex but no hand differences in the isthmus of the corpus callosum. Neurology, 42, 749–752.
  Article PubMed Google Scholar
• Takeda, S., Yamada, S., Ono, S., & Matsuzawa, T. (1988). Age-related changes in the size of the CC. Nippon Ronen Igakkai Zasshi, 25, 292–295.
  Article PubMed Google Scholar
• Uematsu, M., & Kaiya, H. (1988). The morphology of the corpus callosum in schizophrenia: An MRI study. Schizophrenia Research, 1, 391–398.
  Article PubMed Google Scholar
• Weber, G., & Weis, S. (1986). Morphometric analysis of the human corpus callosum fails to reveal sex related differences. Journal für Hirnforschung, 27, 237–240.
  PubMed Google Scholar
• Weis, S., Kimbacher, M., Wenger, E., & Neuhold, A. (1993). Morphometric analysis of the corpus callosum using MR: Correlation of measurements with aging in healthy individuals. American Journal of Neuroradiology, 14, 637–645.
  PubMed Google Scholar
• Weis, S., Weber, G., Wenger, E., & Kimbacher, M. (1988). The human corpus callosum and the controversy about a sexual dimorphism. Psychobiology, 16, 411–415.
  Google Scholar
• Witelson, S. F. (1989). Hand and sex differences in the isthmus and genu of the human corpus callosum: A postmortem morphological study. Brain, 112, 799–835.
  Article PubMed Google Scholar
• Witelson, S. F. (1991). Sex differences in neuroanatomical changes with aging. New England Journal of Medicine, 325, 211–212.
  Article PubMed Google Scholar
• Woodruff, P. W., Pearlson, G. D., Geer, M. J., Barta, P. E., & Chilcoat, H. D. (1993). A computerized magnetic resonance imaging study of corpus callosum morphology in schizophrenia. Psychological Medicine, 23, 45–56.
  Article PubMed Google Scholar
• Yoshii, F., & Duara, R. (1989). Size of the corpus callosum in normal subjects and patients with Alzheimer’s disease. Magnetic resonance imaging study. Clinical Neurology, 29, 1–7.
  PubMed Google Scholar

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