- Dunn TB: Morphology of mammary tumors in mice. In: Homburger F, Fisheman NH (eds) Physiopathology of cancer. New York, Karger, 1959, pp 38–84.
Google Scholar
- Foulds L: The histologic analysis of mammary tumors of mice. I. Scope of investigations and general principles of analysis. J Natl Cancer Inst (7): 701–712, 1956.
Google Scholar
- Foulds L: The histologic analysis of mammary tumors in mice. II. The histology of responsiveness and progression. The origins of tumors. J Natl Cancer Inst (17): 713–754, 1956.
Google Scholar
- Foulds L: The histologic analysis of mammary tumors of mice. III. Organoid tumors. J Natl Cancer Inst (17): 755–782, 1956.
Google Scholar
- Foulds L: The histologic analysis of mammary tumors of mice. IV. Secretion. J Natl Cancer Inst (17): 783–802, 1956.
Google Scholar
- Henderson JS, Rous P: The plating of tumor components on the subcutaneous expanses of young mice. J Exp Med (115): 1211–1230, 1962.
Google Scholar
- Prehn RT: Analysis of antigenic heterogeneity within individual 3-methylcholanthrene-induced mouse sarcomas. J Natl Cancer Inst (45): 1039–1044, 1970.
Google Scholar
- Byers WS, Johnston JO: Antigenic differences among osteogenic sarcoma tumor cells taken from different locations in human tumors. Cancer Res (37): 3173–3183, 1977.
Google Scholar
- Pimm MV, Baldwin RW: Antigenic heterogeneity of primary and metastatic tumors and its implications for immunotherapy. In: Grundmann E (ed) Metastatic tumor growth. Stuttgart, Gustav Fischer Verlag, 1980, pp 305.
Google Scholar
- Pimm MV, Embleton MJ, Baldwin RW: Multiple antigenic specificities within primary 3-methylcholanthrene-induced rat sarcomas and metastases. Int J Cancer (25): 621–629, 1980.
Google Scholar
- Kerbel RS: Implications of immunological heterogeneity of tumors. Nature (280): 358–360, 1979.
Google Scholar
- Albino AP, Lloyd KO, Houghton AN, Oettgen HF, Old LJ: Heterogeneity in surface antigen and glycoprotein expression of cell lines derived from different melanoma metastases of the same patient. J Exp Med (154): 1764–1778, 1981.
Google Scholar
- Miller FR, Heppner GH: Immunologic heterogeneity of tumor cell subpopulations from a single mouse mammary tumor. JNCI (63): 1457–1463, 1979.
Google Scholar
- Killion JJ, Kollmorgen GM: Isolation of immunogenic tumor cells by cell-affinity chromatography. Nature (259): 674–676, 1976.
Google Scholar
- Killion JJ: Immunotherapy with tumor subpopulations. I. Active, specific immunotherapy of L1210 leukemia. Cancer Immunol Immunother (4): 115–119, 1978.
Google Scholar
- Fogel M, Gorelik E, Segal S, Feldman M: Differences in cell surface antigens of tumor metastases and those of the local tumor. JNCI (62): 585–588, 1979.
Google Scholar
- Fuji H, Mihich E: Selection for high immunogenicity in drug resistant sublines of murine lymphomas demonstrated by plaque assay. Cancer Res (35): 946–952, 1975.
Google Scholar
- Schirrmacher V, Bosslet K, Shantz G, Clauer K, Hubsch D: Tumor metastases and cell-mediated immunity in a model system in DBA/2 mice. IV. Antigenic differences between a metastasizing variant, and the parental tumor line revealed by cytotoxic T lymphocytes. Int J Cancer (23): 245–252, 1979.
Google Scholar
- Fuji H, Mihich E, Pressman D: Differential tumor immunogenicity of L1210 and its sublines. J Immunol (119): 983–986, 1977.
Google Scholar
- Gorelick E, Fogel M, Segal S, Feldman M: Tumorassociated antigenic differences between the primary and distant metastatic tumor populations J Supramol Struct (12): 385–402, 1979.
Google Scholar
- Olsson L, Kiger N, Kronstrom H: Sensitivity of cloned high and low-metastatic murine Lewis lung tumor cells to lysis by cytotoxic autoreactive cells. Cancer Res (41): 4706–4709, 1981.
Google Scholar
- Nicolin A, Canti G, Marelli O, Veronese F, Goldin A: Chemotherapy and immunotherapy of L1210 leukemic mice with antigenic tumor sublines. Cancer Res (41): 1358–1362, 1981.
Google Scholar
- Bosslet K, Schirrmacher V: Escape of metastasizing clonal tumor cell variants from tumor-specific cytolytic T lymphocytes. J Exp Med (154): 557–562, 1981.
Google Scholar
- Bosslet K, Schirrmacher V: High-frequency generation of new immunoresistant tumor variants during metastasis of a cloned murine tumor line. Int J Cancer (29): 195–202, 1982.
Google Scholar
- Olsson L, Ebbesen P: Natural polyclonality of spontaneous AKR leukemia and its consequence for so-called specific immunotherapy. JNCI (62): 623–627, 1979.
Google Scholar
- McCune CS, Schapira DV, Henshaw EC: Specific immunotherapy of advanced renal carcinoma: evidence for the polyclonality of metastases. Cancer (47): 1984–1987, 1981.
Google Scholar
- Barranco SC, Haenelt BR, Gee EL: Differential sensitivities of five rat hepatoma cell lines to anticancer drugs. Cancer Res (38): 656–660, 1978.
Google Scholar
- Hakansson L, Trope C: On the presence within tumors of clones that differ in sensitivity to cytostatic drugs. Acta Pathol Microbiol Scand [A] (82): 35–40, 1974.
Google Scholar
- Hakansson L, Trope C: Cell clones with different sensitivity to cytostatic drugs in methylcholanthrene-induced mouse sarcomas. Acta Pathol Microbiol Scand [A] (82): 41–47, 1974.
Google Scholar
- Trope C: Different sensitivity to cytostatic drugs of primary tumor and metastasis of the Lewis lung carcinoma. Neoplasma (22): 171–180, 1975.
Google Scholar
- Lotan R, Nicolson GL: Heterogeneity in growth inhibition by β-_trans_-retinoic acid of metastatic B16 melanoma clones and in vivo selected cell variant lines. Cancer Res (39): 4767–4771, 1979.
Google Scholar
- Heppner GH, Dexter DL, DeNucci T, Miller FR, Calabresi P: Heterogeneity in drug sensitivity among tumor cell subpopulations of a single mammary tumor. Cancer Res (38): 3758–3763, 1978.
Google Scholar
- Barranco SC, Ho D, Derwinko B, Romsdahl MM, Humphrey RM: Differential sensitivities of human melanoma cells grown in vitro to arabinosylcytosine. Cancer Res (32): 2733–2736, 1972.
Google Scholar
- Barranco SC, Derwinko B, Humphrey RM: Differential response by human melanoma cells to 1,2-bis-(2-chloroethyl)-1-nitrosourea and bleomycin. Mutat Res (19): 277–280, 1973.
Google Scholar
- Lotan R: Different susceptibilites of human melanoma and breast carcinoma cell lines to retinoic acid-induced growth inhibition. Cancer Res (39): 1014–1019, 1979.
Google Scholar
- Trope C, Hakansson L, Dencker H: Heterogeneity of human adenocarcinomas of the colon and the stomach as regards sensitivity to cytostatic drugs. Neoplasma (22): 423–430, 1975.
Google Scholar
- Trope C: Different susceptibilities of tumor cell subpopulations to cytotoxic agents. In: Fidler IJ, White RJ (eds) Design of models for testing cancer chemotherapeutic agents. New York, D. Van Nostrand Co., 1982, pp 64–79.
Google Scholar
- Trope C, Aspergen K, Kullander S, Astredt B: Heterogeneous response of disseminated human ovarian cancers to cytostasis in vitro. Acta Obstet Gynecol Scand (58): 543–546, 1979.
Google Scholar
- Siracky J: An approach to the problem of heterogeneity of human tumor-cell populations. Br J Cancer (39): 570–577, 1979.
Google Scholar
- Baylin SB: Clonal selection and heterogeneity of human solid neoplasms. In: Fidler IJ, White RJ (eds) Design of models for testing cancer therapeutic agents. New York, D Van Nostrand Co, 1982, pp 50–63.
Google Scholar
- Biorklund A, Hakansson L, Stenstarn B, Trope C: Heterogeneity of non-Hodgkin's lymphomas as regards sensitivity to cytostatic drugs. Eur J Cancer (16): 654–657, 1980.
Google Scholar
- Baylin SB, Weisburger WR, Eggleston JC, Mendelshon G, Bearnen MA, Abeloff MD, Ettinger DS: Variable content of histaminase, L-dopa decarboxylase and calcitonin in small-cell carcinoma of the lung. Biologic and clinical implications. N Engl J Med (299): 105–110, 1978.
Google Scholar
- Tsuruo T, Fidler IJ: Differences in drug sensitivity among tumor cells from parental tumors, selected variants, and spontaneous metastases. Cancer Res (41): 3058–3064, 1981.
Google Scholar
- DeWys WD: Studies correlating the growth rate of a tumor and its metastases and providing evidence for tumor-related systemic growth-retarding factors. Cancer Res (32): 374–379, 1972.
Google Scholar
- Cifone MA, Kripke ML, Fidler IJ: Growth rate and chromosome number of tumor cell lines with different metastatic potential. J Supramol Struct (11): 467–476, 1979.
Google Scholar
- Cifone MA, Fidler IJ: Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma. Proc Natl Acad Sci USA (77): 1039–1043, 1980.
Google Scholar
- Miller BE, Miller FR, Leith J, Heppner GH: Growth interaction in vivo between tumor subpopulations derived from a single mouse mammary tumor. Cancer Res (40): 3977–3981, 1980.
Google Scholar
- Soule HB, Maloney T, McGrath CM: Phenotypic variance among cells isolated from spontaneous mouse mammary tumors in primary suspension culture. Cancer Res (41): 1154–1164, 1981.
Google Scholar
- Zupi G, Mauro F, Sacchi A: Cloning in vitro and in vivo of Lewis lung carcinoma: properties and characteristics. Br J Cancer (41): 309–310, 1981.
Google Scholar
- Talmadge JE, Starkey JR, Stanford DR: In vitro characteristics of metastatic variant subclones of restricted genetic origin. J Supramol Struct (15): 139–152, 1981.
Google Scholar
- Danielson KG, Anderson LW, Hosick HL: Selection and characterization in culture of mammary tumor cells with distinctive growth properties in vivo. Cancer Res (40): 1812–1819, 1980.
Google Scholar
- Rabotti G: Ploidy of primary and metastatic human tumours. Nature (183): 1276–1277, 1959.
Google Scholar
- Ito E, Moore GE: Characteristic differences in clones isolated from an S37 ascites tumor in vitro. Exp Cell Res (48): 440–447, 1967.
Google Scholar
- Mittleman F: The chromosomes of fifty primary Rous rat sarcomas. Hereditas (69): 155–186, 1971.
Google Scholar
- Ohno S: Genetic implication of karyological instability of malignant somatic cells. Physiol Rev (51): 496–526, 1971.
Google Scholar
- Bohm N, Sondritter W: DNA in human tumors: a cytophotometric study. Curr Top Pathol (60): 152–219, 1975.
Google Scholar
- Straus MJ: In: Straus MJ (ed) Lung cancer. New York, Grune and Stratton, 1977, pp 19–32.
Google Scholar
- Vindelov LV: Flow microfluorometric analysis of nuclear DNA in cells from solid tumors and cell suspensions. Cell Pathol (24): 227–242, 1977.
Google Scholar
- Shapiro JR, Yung W, Shapiro WR: Isolation, karyotype and clonal growth of heterogeneous subpopulations of human malignant gliomas. Cancer Res (41): 2349–2359, 1981.
Google Scholar
- Vindelov LV, Hansen HH, Christensen IJ, Spang-Thomsen M, Hirsch FR, Hansen M, Nissen NI: Clonal heterogeneity of small-cell anaplastic carcinoma of the lung demonstrated by flow cytometric DNA analysis. Cancer Res (40): 4295–4300, 1980.
Google Scholar
- Tilley WD, Keightley DD, Cant ELM: Intersite variation of α estrogen receptors in human breast cancer. Br J Cancer (38): 544–546, 1978.
Google Scholar
- Dexter DL, Kowalski HM, Blazer BA, Fligiel Z, Vogel R, Heppner GH: Heterogeneity of tumor cells from a single mouse mammary tumor. Cancer Res (38): 3174–3181, 1978.
Google Scholar
- Kusyk CJ, Seski JC, Medlin WV, Edwards CL: Progressive chromosome changes associated with different sites of one ovarian carcinoma. INCI (66): 1021–1025, 1981.
Google Scholar
- Fidler IJ, Gruys E, Cifone MA, Barnes Z, Bucana C: Demonstration of multiple phenotypic diversity in a murine melanoma of recent origin. JNCI (67): 947–956, 1981.
Google Scholar
- Niles RM, Makarski JS: Hormonal activation of adenylate cyclase in mouse melanoma metastatic variants. J Cell Physiol (96): 355–359, 1978.
Google Scholar
- Tao TW, Burger MM: Nonmetastasizing variants selected from metastasizing melanoma cells. Nature (270): 437–438, 1977.
Google Scholar
- Brunson KW, Nicolson GL: Selection and biologic properties of malignant variants of a murine lymphosarcoma. JNCI (61): 1499–1503, 1978.
Google Scholar
- Raz A, McLellan WE, Hart IR, Bucana CD, Hoyer LC, Sela BA, Dragsten P, Fidler IJ: Cell surface properties of B16 melanoma variants with differing metastatic potential. Cancer Res (40): 1645–1651, 1980.
Google Scholar
- Reading CL, Belloni DN, Nicolson GL: Selection and in vivo properties of lectin-attachment variants of malignant murine lymphosarcoma cell lines. JNCI (64): 1241–1249, 1980.
Google Scholar
- Franks LM, Estrogen-treated prostatic cancer. Cancer (13): 490–501, 1960.
Google Scholar
- Sluyser M, Evers SG, DeGoey CC: Sex hormone receptors in mammary tumours of GR mice. Nature (263): 386–389, 1976.
Google Scholar
- Sluyser M, Van Nie R: Estrogen receptor content and hormone-responsive growth of mouse mammary tumors. Cancer Res (34): 3252–3257, 1974.
Google Scholar
- Brennan MJ, Donegan WL, Appleby DE: The variability of estrogen receptors in metastatic breast cancer. Am J Surg (137): 260–262, 1979.
Google Scholar
- Isaacs JT, Wake N, Coffey DS, Sandberg AA: Genetic instability coupled to clonal selection as a mechanism for tumor progression in the Dunning R-3327 rat prostatic adenocarcinoma system. Cancer Res (42): 2353–2361, 1981.
Google Scholar
- Isaacs JR, Coffey DS: Adaptation versus selection as the mechanism responsible for the relapse of prostatic cancer to androgen ablation therapy as studied in the Dunning R-3327H adenocarcinoma. Cancer Res (41): 5070–5075, 1981.
Google Scholar
- Semple TV, Moore GE, Morgan RT, Woods LK, Quinn LA: Multiple cell lines from patients with malignant melanoma: morphology, karyology and biochemical analysis. JNCI (68): 365–371, 1982.
Google Scholar
- Kiricuta I, Mustea I, Rogozaw I, Simu G: Relations between tumor and metastases. I. Aspects of the crabtree effect. Cancer (68): 365–371, 1982.
Google Scholar
- Baylin SB, Abeloff MD, Wieman KC, Tomford JW, Ettinger DS: Elevated histaminase (diamine oxidase) activity in small-cell carcinoma of the lung. N Engl J Med (293): 1286–1290, 1975.
Google Scholar
- Lavner EH, Rutherford CL: Implementation of micromethods to resolve problems of human breast tumor heterogeneity in analysis of cyclic 3′: 5′ nucleotide phosphodieiterase. Cancer Res (42): 1661–1668, 1982.
Google Scholar
- Angello JC, Danielson KG, Anderson LW, Hosick HL: Glycosaminoglycan synthesis by subpopulations of epithelial cells from a mammary adenocarcinoma. Cancer Res (42): 2207–2210, 1982.
Google Scholar
- Willis RA: The mode of origin of tumours (fields of origin of epithelial tumours). In: Willis RA (ed) Pathology of tumors. London, Butterworth, 1960, p 108.
Google Scholar
- Foulds L: The experimental study of tumor progression: a review. Cancer Res (14): 327–339, 1954.
Google Scholar
- Reddy AL, Fialkow PJ: Multicellular origin of fibrosarcomas in mice induced by the chemical carcinogen 3-methylcholanthrene. J Exp Med (150): 878–886, 1980.
Google Scholar
- Tanouka H, Tanaka K: Evidence for single cell origin of 3-methylcholanthrene-induced fibrosarcomas in mice with cellular mosaicism. Cancer Res (42): 1856–1858, 1982.
Google Scholar
- Fialkow PJ: Use of genetic markers to study cellular origin and development of tumors in human females. Adv Cancer Res (15): 191–226, 1972.
Google Scholar
- Fialkow PJ: Clonal origin of human tumors. Biochim Biophys Acta (458): 283–310, 1976.
Google Scholar
- Nowell PS: The clonal evolution of tumor cell subpopulations. Science (194): 23–28, 1976.
Google Scholar
- Barrett CJ, Ts'o POP: Evidence for the progressive nature of neoplastic transformation in vitro. Proc Natl Acad Sci USA (75): 3761–3765, 1978.
Google Scholar
- Iannaccone PM, Gardner RL, Harris H: The cellular origin of chemically induced tumors. J Cell Sci (29): 249–255, 1978.
Google Scholar
- Rubin H: Is somatic mutation the major mechanism of malignant transformation? JNCI (64): 995–1000, 1980.
Google Scholar
- Klein E: Gradual transformation of solid into ascites tumors. Permanent difference between the original and the transformed sublines. Cancer Res (14): 482–485, 1954.
Google Scholar
- Klein E: Gradual transformation of solid into ascites tumors. Evidence favoring the mutation-selection theory. Exp Cell Res (8): 188–212, 1955.
Google Scholar
- Potter VR: Phenotypic diversity in experimental hepatomas: the concept of partially blocked ontogeny. Br J Cancer (1): 23–29, 1978.
Google Scholar
- Hager C, Miller FR, Heppner GH: Influence of serial transplantation on the immunological-clinical correlates of BALB/cf C3H mouse mammary tumors. Cancer Res (38): 2492–2498, 1978.
Google Scholar
- Hager JC, Russo J, Ceriani RL, Peterson JA, Fligiel S, Jolly G, Heppner GH: Epithelial characteristics of five subpopulations of a heterogeneous strain BALB/cf C3H mouse mammary tumor. Cancer Res (41): 1720–1730, 1981.
Google Scholar
- Loeb LA, Springate CG, Battula N: Errors in DNA replication as a basis of malignant changes. Cancer Res (34): 2311–2321, 1974.
Google Scholar
- Waren ST, Schultz RA, Chang C, Wade HJ, Trosko JE: Elevated spontaneous mutation rate in Bloom syndrome fibroblasts. Proc Natl Acad Sci USA (78): 3133–3137, 1981.
Google Scholar
- Cifone MA, Fidler IJ: Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms. Proc Natl Acad Sci USA (78): 6949–6952, 1981.
Google Scholar
- Fidler IJ, Hart IR: Biological and experimental consequences of the zonal composition of solid tumors. Cancer Res (41): 3266–3267, 1981.
Google Scholar
- Koch FE: Zur frage der metastazenbildung bei Limpftumoren. Z Krebsforsch (48): 495–499, 1939.
Google Scholar
- Fidler IJ: Selection of successive tumor lines for metastasis. Nature (242): 148–149, 1973.
Google Scholar
- Fidler IJ, Kripke ML: Metastasis results from preexisting variant cells within a malignant tumor. Science (197): 893–895, 1977.
Google Scholar
- Kripke ML, Fidler IJ: Enhanced experimental metastasis of ultraviolet light-induced fibrosarcomas in ultraviolet light-irradiated syngeneic mice. Cancer Res (40): 625–629, 1980.
Google Scholar
- Kripke ML, Gruys E, Fidler IJ: Metastatic heterogeneity of cells from an ultraviolet light-induced murine fibrosarcoma of recent origin. Cancer Res (38): 2962–2967, 1978.
Google Scholar
- Fidler IJ, Hart IR: The origin of metastatic heterogeneity in tumors. Eur J Cancer (17): 487–494, 1981.
Google Scholar
- Tarin D, Price JE: Metastatic colonization potential of primary tumour cells in mice. Br J Cancer (39): 740–754, 1979.
Google Scholar
- Schmitt M, Daynes RA: Heterogeneity of tumorigenicity phenotype in murine tumors. I. Characterization of regressor and progressor clones isolated from a nonmutagenized ultraviolet regressor tumor. J Exp Med (153): 1344–1359, 1981.
Google Scholar
- Dexter DL, Kowalski HM, Blazar BA, Fligiel Z, Vogel R, Heppner GH: Heterogeneity of tumor cells from a single mouse mammary tumor. Cancer Res (38): 3174–3181, 1978.
Google Scholar
- Brattain MG, Fine WD, Khaled FM, Thompson J, Brattain DE: Heterogeneity of malignant cells from a human colonic carcinoma. Cancer Res (41): 1751–1758, 1981.
Google Scholar
- Stackpole CW: Distinct lung-colonizing and lung-metastasizing cell populations in B16 mouse melanoma. Nature (289): 798–800, 1981.
Google Scholar
- Suzuki N, Withers R, Koehler MW: Heterogeneity and variability of artificial lung colony-forming ability among clones from mouse fibrosarcoma. Cancer Res (38): 3349–3351, 1978.
Google Scholar
- Poste G, Fidler IJ: The pathogenesis of cancer metastasis. Nature (283): 139–146, 1980.
Google Scholar
- Briles EB, Kornfeld S: Isolation and metastatic properties of detachment variants of B16 melanoma cells. JNCI (60): 1217–1222, 1978.
Google Scholar
- Poste GH, Doll J, Hart IR, Fidler IJ: Selection of variant lines with increased invasive capacities. Cancer Res (40): 1636–1644, 1980.
Google Scholar
- Hart IR: Selection and characterization of an invasive variant of the B16 melanoma. Am J Pathol (97): 587–600, 1979.
Google Scholar
- Fidler IJ, Bucana C: Mechanism of tumor cell resistance to lysis by syngeneic lymphocytes. Cancer Res (37): 3945–3956, 1977.
Google Scholar
- Schirrmacher V, Bosslet K: Tumor metastases and cell-mediated immunity in a model system in DBA/2 mice. X. Immunoselection of tumor variants differing in tumor antigen expression and metastatic capacity. Int J Cancer (25): 781–788, 1980.
Google Scholar
- Frost PH, Kerbel RS: Immunoselection in vitro of a nonmetastatic variant from a highly metastatic tumor. In J Cancer (27): 381–385, 1981.
Google Scholar
- Talmadge JE, Meyers KM, Prieur DJ, Starkey JR: Role of NK cells in tumour growth and metastasis in beige mice. Nature (284): 622–624, 1980.
Google Scholar
- Hanna N, Fidler IJ: Relationship between metastatic potential and resistance to NK cell-mediated cytotoxicity in three murine tumor systems. JNCI (66): 1183–1190, 1981.
Google Scholar
- Gorelik E, Feldman M, Segal S: Selection of 3LL tumor subline resistant to natural effector cells concomitantly selected for increased metastatic potency. Cancer Immunol Immunother (12): 105–109, 1982.
Google Scholar
- Talmadge JE, Starkey JR, Davis WC, Cohen A: Introduction of metastatic heterogeneity by short term in vivo passage of a cloned transformation cell line. J Supramol Struct (120): 227, 1979.
Google Scholar
- Shearman PJ, Longenecker BM: Selection for virulence and organ-specific metastasis of Herpes virus-transformed lymphoma cells. Int J Cancer (25): 363–369, 1980.
Google Scholar
- Enders JF, Diamondopoulos FT: A study of variation and progression in oncongenicity in an SV 40-transformed hamster heart cell line and its clones. Proc Soc Biol (171): 431–443, 1969.
Google Scholar
- Talmadge JE, Fidler IJ: Cancer metastasis is either selective or random depending on the parent tumour population. Nature (289): 301–303, 1981.
Google Scholar
- Talmadge JE, Fidler IJ: Enhanced metastatic potential of tumor cells harvested from spontaneous metastases of heterogeneous murine tumors. JNCI (69): 975–980, 1982.
Google Scholar
- Talmadge JE, Key ME, Hart IR: Characterization of a murine ovarian reticulum cell sarcoma of histiocytic origin. Cancer Res (41): 1271–1280, 1981.
Google Scholar
- Hart IR, Talmadge JE, Fidler IJ: Metastatic behavior of murine reticulum cell sarcoma exhibiting organ-specific growth. Cancer Res (41): 1281–1287, 1981.
Google Scholar
- Neri A, Welch D, Kawaguchi T, Nicolson GL: Development and biologic properties of malignant cell sublines and clones of a spontaneously metastasizing rat mammary adenocarcinoma. JNCI (68): 507–517, 1982.
Google Scholar
- Raz A, Hanna N, Fidler IJ: In vivo isolation of a metastatic tumor cell variant involving selective and nonadaptive processes. JNCI (66): 183–189, 1981.
Google Scholar
- Nicolson GL, Custead SE: Tumor metastasis is not due to adaptation of cells to a new organ environment. Science (215): 176–178, 1982.
Google Scholar
- Mantovani A, Giavazzi R, Alessandri G, Spreafico F, Garattini S: Characterization of tumor lines derived from spontaneous metastases of a transplantable murine sarcoma. Eur J Cancer (17): 71–76, 1981.
Google Scholar
- Giavazzi R, Alessandri G, Spreafico F, Garattini S, Mantovani A: Metastasizing capacity of tumour cells from spontaneous metastases of transplanted murine tumours. Br J Cancer (42): 432–442, 1980.
Google Scholar
- Talmadge JE, Wolman S, Fidler IJ: Evidence for the clonal origin of spontaneous metastases. Science (217): 361–363, 1982.
Google Scholar