A biochemical hallmark of apoptosis: Internucleosomal degradation of the genome (original) (raw)
References
Kerr JFR, Wyllie AH, Currie AR: A basic biological phenomenon with wide-ranging implication in tissue kinetics. Br J Cancer 26: 239–257, 1972 Google Scholar
Ijiri K, Potten CS: Further studies on the response of intestinal crypt cells of different hierarchical status to eighteen different cytotoxic agents. Br J Cancer 55: 113–123, 1987 Google Scholar
Hinchliffe JR, Ede DA: Cell death and the development of limb form and skeletal pattern in normal and wingless (ws) chick embryos. J Embryol Exp Morphol 30: 753–772, 1973 Google Scholar
Saunders JW: Death in embryonic systems. Science 154: 604–612, 1966 Google Scholar
Weber R: The tadpole tail as a model system for studies on the mechanism of hormone-dependent tissue involution. Gen Comp Endocrinol [Suppl 2]: 408–416, 1969
Lockshin RA, Beaulaton J: Programmed cell death. Cytochemical evidence for lysosomes during the normal breakdown of the intersegmental muscles. J Ultrastruct Res 46: 43–62, 1974 Google Scholar
Counis MF, Chaudun E, Allinquant B, Muel AS, Sanval M, Skidmore C, Courtois Y: The lens: A model for chromatin degradation studies in terminally differentiating cells. Int J Biochem 21: 235–242, 1989 Google Scholar
Rotello RJ, Hocker MB, Gerschenson E: Biochemical evidence for programmed cell death in rabbit uterine epithelium. Am J Physiol 134: 491–495, 1989 Google Scholar
Kyprianou N, Isaacs JT: Activation of programmed cell death in the rat ventral prostate after castration. Endocrinology 122: 552–562, 1988 Google Scholar
Wyllie AH, Kerr JFR, Macaskill IAM, Currie AR: Adrenocortical cell deletion: The role of ACTH. J Pathol 111: 85–94, 1973 Google Scholar
Walker NI, Bennett RE, Kerr JFR: Cell death by apoptosis during involution of the lactating breast in mice and rats. Am J Anat 185: 19–32, 1989 Google Scholar
Wyllie AH, Kerr JFR, Currie AR: Cell death: The significance of apoptosis. Int Rev Cytol 68: 251–306, 1980 Google Scholar
Compton MM, Cidlowski JA: Thymocyte apoptosis. A model of programmed cell death. Trends Endocrinol Met 3: 17–23, 1992 Google Scholar
Waring P, Kos FJ, Müllbacher A: Apoptosis or programmed cell death. Medicinal Res Rev 11: 219–236, 1991 Google Scholar
Arends MJ, Wyllie AH: Apoptosis: Mechanisms and roles in pathology. Int Rev Exptl Path 32: 223–254, 1991 Google Scholar
Wyllie AH: Cell death. Int Rev Cytol 17 [Suppl]: 755–785, 1987 Google Scholar
Trump BF, Goldblatt PJ, Stowell RE: Studies on necrosis of mouse liver in vitro. Ultrastructural alterations in mitochondria of hepatic parenchymal cell. Lab Invest 14: 343–371, 1965 Google Scholar
Compton MM, Gibbs PS, Swicegood LR: Glucocorticoid mediated activation of DNA degradation in avian lymphocytes. Gen Comp Endocrinol 80: 68–79, 1990 Google Scholar
Wyllie AH: Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555–556, 1980 Google Scholar
Compton MM, Johnson LR, Gibbs PS: Activation of thymocyte DNA degradation by endogenous glucocorticoids. Poul Sci 70: 521–529, 1991 Google Scholar
Arends MJ, Morris RG, Wyllie AH: Apoptosis: The role of the endonuclease. Am J Pathol 136: 593–608, 1990 Google Scholar
Alnemri ES, Litwack G: Activation of internucleosomal DNA cleavage in human CEM lymphocytes by glucocorticoid and novobiocin: Evidence for a non-Ca2+ requiring mechanism(s). J Biol Chem 265: 17323–17333, 1990 Google Scholar
Vanderbilt JN, Bloom KS, Anderson JN: Endogenous nuclease: Properties and effects on transcribed genes in chromatin. J Biol Chem 257: 13009–13027, 1982 Google Scholar
Wyllie AH, Morris RG, Smith AC, Dunlop D: Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis. J Pathol 142: 67–77, 1984 Google Scholar
Compton MM, Cidlowski JA: Rapid In vivo effects of glucocorticoids on the integrity of rat lymphocye genomic deoxyribonucleic acid. Endocrinology 118: 38–45, 1986 Google Scholar
Cohen JJ, Duke RC: Glucocorticoid activation of a calcium dependent endonuclease in thymocyte nuclei leads to cell death. J Immunol 132: 38–42, 1984 Google Scholar
McConkey DJ, Nicotera P, Hartzell P, Bellomo G, Wyllie AH, Orrenius S: Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration. Arch Biochem Biophys 269: 365–370, 1989 Google Scholar
Zheng LM, Zychlinsky A, Liu CC, Objcius DM, Young JD: Extracellular ATP as a trigger for apoptosis or programmed cell death. J Cell Biol 112: 279–288, 1991 Google Scholar
McConkey DJ, Hartzell P, Orrenius S: Rapid turnover of endogenous endonuclease activity in thymocytes: Effects of inhibitors of macromolecular synthesis. Arch Biochem Biophys 278: 284–287, 1990 Google Scholar
Gardner P, Alcover A, Kuno M, Weyand CM, Goronzy J, Reinherz EL: Triggering of T-lymphocytes via either T3-Ti or T11 surface structures opens a voltage-insensitive plasma membrane calcium-permeable channel: requirement for IL-2 gene function. J Biol Chem 264: 1068–1076, 1989 Google Scholar
McConkey DJ, Hartzell P, Jondal M, Orrenius S: Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C. J Biol Chem 264: 13399–13402, 1989 Google Scholar
Rodriguez-Tarducy G, Collins M, López-Rivas A: Regulation of apoptosis in interleukin-3-dependent hemopoietic cells by interleukin-3 and calcium ionophores. EMBO J 9: 2997–3002, 1990 Google Scholar
Alnemri ES, Litwack G: Glucocorticoid-induced lymphocytolysis is not mediated by an induced endonuclease. J Biol Chem 264: 4104–4111
McConkey DJ, Orrenius S, Jondal M: Agents that elevate cAMP stimulate DNA fragmentation in thymocytes. J Immunol 145: 1227–1230, 1990 Google Scholar
Suzuki K, Tadakuma T, Kizaki H: Modulation of thymocyte apoptosis by isoproterenol and prostaglandin E2. Cellular Immunol 134: 235–240, 1991 Google Scholar
Burton K: A study of the conditions and mechanism of the diphenylamine reaction for the estimation of deoxyribonucleic acid. Biochem J 62: 315–323, 1956 Google Scholar
Zeleznick AJ, Ihrig LL, Bassett SG: Developmental expression of Ca++/Mg++-dependent endonuclease activity in rat granulosa and luteal cells. Endocrinology 125: 2218–2220, 1989 Google Scholar
Koury MJ, Bondurant MC: Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells. Science 248: 378–381, 1991 Google Scholar
Masters JN, Finch CE, Sapolsky RM: Glucocorticoid endangerment of hippocampal neurons does not involve deoxyribonucleic acid cleavage. Endocrinology 124: 3083–3088, 1989 Google Scholar
Facchinetti A, Tessarollo L, Mazzocchi M, Kingston R, Collavo D, Viasi G: An improved method for the detection of DNA fragmentation. J Immunol Meth 136: 125–131, 1991 Google Scholar
Compton MM, Haskill JS, Cidlowski JA: Analysis of glucocorticoid actions on rat thymocyte DNA by fluorescence-activated flow cytometry. Endocrinology 122: 2158–2164, 1988 Google Scholar
Swat W, Ignatowicz L, Kisielow P: Detection of apoptosis of immature CD4+8+ thymocytes by flow cytometry. J Immol Meth 137: 79–87, 1991 Google Scholar
Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C: A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immol Meth 139: 271–279, 1991 Google Scholar
Rosenthal AL, Lacks SA: Nuclease detection in SDS-polyacrylamide gel electrophoresis. Anal Biochem 80: 76–90, 1977 Google Scholar
Compton MM, Cidlowski JA: Identification of a glucocorticoid-induced nuclease in thymocytes: A potential ‘lysi gene’ product. J Biol Chem 262: 8288–8292, 1987 Google Scholar
Van denBogert C, Bakker HM, Kuzela S, Melis TE, Kroon AM: Changes in nuclear protein pattern by glucocorticoid treatment of lymphoid cells. J Steroid Biochem 33: 955–963, 1989 Google Scholar
Baxter GD, Smith PJ, Lavin MF: Molecular changes associated with induction of cell death in a human T-cell leukemia line: Putative nuclease identified as histones. Biochem Biophys Res Commun 162: 30–37, 1989 Google Scholar
Gaido ML, Cidlowski JA: Identification, purification, and characterization of a calcium dependent endonuclease (NUC18) from apoptotic rat thymocytes: NUC18 is not histone H2B. J Biol Chem 266: 18580–18585, 1991 Google Scholar
Compton MM: Development of a apoptosis endonuclease assay. DNA and Cell Biol 10: 133–141, 1991 Google Scholar
Schwartzman RA, Cidlowski JA: Internucleosomal deoxyribonucleic acid cleavage activity in apoptotic thymocytes: Detection and endocrine regulation. Endocrinology 128: 1190–1197, 1991 Google Scholar
Telford DJ, Stewart BW: Micrococcal nuclease: Its specificity and use for chromatin analysis. Int J Biochem 21: 127–137, 1989 Google Scholar
Hewish DR, Burgoyne LA: The calcium dependent endonuclease activity of isolated nuclear preparations. Relationships between its occurrence and the occurrence of other classes of enzymes found in nuclear preparations. Biochem Biophys Res Commun 52: 475–481, 1973 Google Scholar
Ishida R, Akiyoshi H, Takahashi T: Isolation and purification of calcium and magnesium dependent endonuclease from rat liver nuclei. Biochem Biophys Res Commun 56: 703–710, 1974 Google Scholar
Nakamura M, Sakaki Y, Wantanabe N, Takagi Y: Purification and characterization of the Ca2+ plus Mg2+-dependent endodeoxyribonuclease from calf thymus chromatin. J Biochem 89: 143–152, 1981 Google Scholar
Sokolova IA, Khodarev NN, Aleksandrova SS, Votrin II: Isolation and investigation of Ca/Mg-dependent endonuclease from cell nuclei of human spleen lymphocytes. Biokhimiya 53: 1163–1173, 1988 Google Scholar
Nikonova LV, Zotova RN, Umanski SC: Isolation of Ca2+, Mg2+ dependent nuclease from calf thymus chromatin. Biokhimiya 54: 1709–1718, 1989 Google Scholar
Ucker DS: Cytotoxic T lymphocytes and glucocorticoids activate an endogenous suicide process in target cells. Nature 327: 62–64, 1987 Google Scholar
Franceschi C: Cell proliferation cell death and aging. Aging 1: 3–15, 1989 Google Scholar
Aaronson JA: Growth factors and cancer. Science 254: 1146–1153, 1991 Google Scholar