Anaplastic (malignant) ganglioglioma arising from heterotopic grey matter nodules (original) (raw)
Summary
Anaplastic ganglioglioma is a rare malignant neoplasm. The short clinical course and the anaplastic histological features are characteristics of malignant ganglioglioma. Immunohistochemistry is necessary for the final diagnosis. The MRI appearances are described here for the first time in literature. Nodular grey matter heterotopias had been demonstrated and the patient developed an anaplastic ganglioglioma two years later, on the same place where the grey matter heteropias had been seen. This finding supports the hypothesis that these tumours may arise from grey matter nodules.
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Authors and Affiliations
- Department of Radiology, Leuven, Belgium
Philippe Demaerell, Myriam Droessaert, Guy Wilms & Albert L. Baert - Department of Neuropathology, Leuven, Belgium
Martin Lammens - Department of Oncology, Leuven, Belgium
Johan Menten - Department of Neurosurgery, Leuven, Belgium
Bart Nuttin - Laboratory for Medical Imaging Research, Leuven, Belgium
Rudy Verbeecks - University Hospitals K.U.L., Leuven, Belgium
Martin Lammens
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- Philippe Demaerell
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Demaerell, P., Droessaert, M., Lammens, M. et al. Anaplastic (malignant) ganglioglioma arising from heterotopic grey matter nodules.J Neuro-Oncol 30, 237–242 (1996). https://doi.org/10.1007/BF00177274
- Issue Date: December 1996
- DOI: https://doi.org/10.1007/BF00177274