Anaplastic (malignant) ganglioglioma arising from heterotopic grey matter nodules (original) (raw)

Summary

Anaplastic ganglioglioma is a rare malignant neoplasm. The short clinical course and the anaplastic histological features are characteristics of malignant ganglioglioma. Immunohistochemistry is necessary for the final diagnosis. The MRI appearances are described here for the first time in literature. Nodular grey matter heterotopias had been demonstrated and the patient developed an anaplastic ganglioglioma two years later, on the same place where the grey matter heteropias had been seen. This finding supports the hypothesis that these tumours may arise from grey matter nodules.

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Authors and Affiliations

  1. Department of Radiology, Leuven, Belgium
    Philippe Demaerell, Myriam Droessaert, Guy Wilms & Albert L. Baert
  2. Department of Neuropathology, Leuven, Belgium
    Martin Lammens
  3. Department of Oncology, Leuven, Belgium
    Johan Menten
  4. Department of Neurosurgery, Leuven, Belgium
    Bart Nuttin
  5. Laboratory for Medical Imaging Research, Leuven, Belgium
    Rudy Verbeecks
  6. University Hospitals K.U.L., Leuven, Belgium
    Martin Lammens

Authors

  1. Philippe Demaerell
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  2. Myriam Droessaert
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  3. Martin Lammens
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  4. Johan Menten
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  5. Bart Nuttin
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  6. Rudy Verbeecks
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  7. Guy Wilms
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  8. Albert L. Baert
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Demaerell, P., Droessaert, M., Lammens, M. et al. Anaplastic (malignant) ganglioglioma arising from heterotopic grey matter nodules.J Neuro-Oncol 30, 237–242 (1996). https://doi.org/10.1007/BF00177274

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