An assessment of a collagen/vicryl composite membrane to repair defects of the urinary bladder in rabbits (original) (raw)

Summary

Collagen/vicryl (Polyglactin) composite membrane has been used to repair full-thickness defects in the urinary bladder of rabbits. The material has been shown to be biodegradable, prevent leakage of urine, and is readily replaced by collagenous scar tissue lined with a urothelium. Regeneration of smooth nuscle has been observed in the repair area of some animals. The results suggest that such a material may well be of use to urologists wishing to augment contracted bladders or in the repair of bladder fistulae in human subjects, thereby avoiding the use of bowel or other material e.g. omentum.

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References

1. Gorham SD, Monsour MJ, Scott R (1987) The in-vitro assessment of a collagen/vicryl (Polyglactin) composite film together with condidate suture materials for use in urinary tract surgery. I. Physical testing. Urol Res 15:53–59
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2. Mohammed R, Monsour MJ, Gorham SD, French DA, Scott R (1987) The use of a biodegradable collagen/vicryl composite membrane to repair partial nephrectomy in rabbits. Urol Res 15:239–242
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3. Tsuji I, Shiraishi Y, Kassai T, Kunishma K, Orikasa S, Abe N (1967) Further experimental investigations on bladder reconstruction without using the intestine. J Urol 97:1021
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Authors and Affiliations

1. Department of Urology, Glasgow Royal Infirmary, Alexander Parade, Glasgow, UK
   M. J. Monsour FRCS, R. Mohammed & R. Scott
2. Moodiesburn, Devro Ltd, Chryston, Glasgow, UK
   S. D. Gorham
3. Sighthill Industrial Estate, Ethicon Ltd, Bankhead Avenue, Edinburgh, UK
   D. A. French

Authors

1. M. J. Monsour FRCS
2. R. Mohammed
3. S. D. Gorham
4. D. A. French
5. R. Scott

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Monsour, M.J., Mohammed, R., Gorham, S.D. et al. An assessment of a collagen/vicryl composite membrane to repair defects of the urinary bladder in rabbits.Urol. Res. 15, 235–238 (1987). https://doi.org/10.1007/BF00262106

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• Accepted: 21 November 1986
• Issue date: August 1987
• DOI: https://doi.org/10.1007/BF00262106

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