Effect of nicotinamide treatment on the residual insulin secretion in Type 1 (insulin-dependent) diabetic patients (original) (raw)
References
Eisenbarth GS (1986) Type I diabetes mellitus. A chronic autoimmune disease. N Engl J Med 314: 1360–1368 Google Scholar
Stauffacher W, Burr I, Gutzeit A, Beaven D, Velinsky J, Renold AE (1970) Streptozotocin diabetes: time course of irreversible B-cell damage; further observations on prevention by nicotinamide. Proc Soc Exp Biol Med 133: 194–200 Google Scholar
Yonemura Y, Takashima T, Miwa K, Miyazadi I, Yamamoto H, Okamoto H (1984) Amélioration of diabetes mellitus in partially depancreatized rats by poly (ADP-ribose) synthetase inhibitors. Evidence of islet B-cell regeneration. Diabetes 33: 401–404 Google Scholar
Yamada K, Nonaka K, Hanafusa T, Miyazaki A, Toyoshima H, Tarvis S (1982) Preventive and therapeutic effects of large dose nicotinamide injections on diabetes associated with insulitis. An observation in non obese diabetic (NOD) mice. Diabetes 31: 749–753 Google Scholar
Rossini AA, Like AA, Chick WL, Appel MC, Cahill GF (1977) Studies of streptozotocin-induced insulitis and diabetes. Proc Nat Acad Sci USA 74: 2485–2489 Google Scholar
Nomikos IN, Prowse SJ, Carotenuto P, Lafferty KJ (1986) Combined treatment with nicotinamide and desferrioxamine prevents islet allograft destruction in NOD mice. Diabetes 35: 1302–1304 Google Scholar
Hawkins DR (1968) Treatment of schizophrenia based on the medical model. J Schizophr 2: 3–10 Google Scholar
Hoffer A (1969) Safety, side effects and relative lack of toxicity of nicotinic acid and nicotinamide. Schizophrenia 1: 78–87 Google Scholar
The Coronary Drug Project Research Group (1975) Clofibrate and Niacin in coronary heart disease. J Am Med Assoc 231: 360–381 Google Scholar
Ma A, Medenica M (1983) Response of generalized granuloma annulare to high dose Nicotinamide. Arch Dermatol 119: 836–839 Google Scholar
Vague P, Vialettes B, Lassmann-Vague V, Vallo JJ (1987) Nicotinamide may extend remission phase in insulin-dependent diabetes. Lancet I: 619–620 Google Scholar
Mirouze J, Selam JL, Pham TL, Mendoza A, Orsetti A (1978) Sustained insulin induced remissions of juvenile diabetes by means of an artificial pancreas. Diabetologia 14: 223–227 Google Scholar
Vague P, Vialettes B, Lassmann V, Moulin JP, Mercier P (1985) Sustained initial remission induced by intensive insulin treatment in type I diabetes. Possible role of the genetic background. Acta Diabetol Lat 21: 295–304 Google Scholar
Mistura L, Beccaria L, Meschi F, Flores D'Arlais A, Pellini C, Puzzovio M, Chiumello G (1987) Prednisone treatment in newly diagnosed type I diabetes children: 1-year follow-up. Diabetes Care 10: 38–43 Google Scholar
Sochett EB, Daneman D, Clarson C, Ehrlich RM (1987) Factors affecting and patterns of residual insulin secretion during the first year of Type 1 (insulin-dependent) diabetes mellitus in children. Diabetologia 30: 453–459 Google Scholar
The DCCT Research Group (1987) Effects of age, duration and treatment of insulin-dependent diabetes mellitus on residual B-cell function: observation during eligibility testing for Diabetes control and complications trial (DCCT). J Clin Endocrinol Metab 65: 30–36 Google Scholar
Kaneto T (1974) Radioimmunoassay of human proinsulin C-peptide using synthetic human connecting peptide. Endocrinol Jpn 21: 141–150 Google Scholar
Irvine WJ, Mc Callum CJ, Gray RS, Campbell CJ, Duncan LJP, Farquhar JW, Vaughan EH, Morris PJ (1977) Pancreatic islet cell antibodies in diabetes mellitus correlated with the duration and type of diabetes, coexistent autoimmune disease and HLA type. Diabetes 26: 138–147 Google Scholar
Madsbad S, Faber OK, Binder C, McNair P, Christiansen C, Transbol I (1978) Prevalence of residual Beta-cell function in insulin dependent diabetics in relation to age at onset and duration of diabetes. Diabetes 27 [Suppl 1]: 262–264 Google Scholar
Madsbad S, Krarup T, Regeur L, Faber OK, Binder C (1981) Effect of strict blood glucose control on residual B-cell function in insulin-dependent diabetics. Diabetologia 20: 530–534 Google Scholar
Wallensteen M, Dahlquist G, Persson B, Landin-Olsson M, Lernmark Å, Sundkvist G, Thalme B (1988) Factors influencing the magnitude, duration and fall of B-cell function in Type 1 (insulin-dependent) diabetic children followed for two years from their clinical diagnosis. Diabetologia 31: 664–669 Google Scholar
Mandfield-Jones S, Jones SK, Peach RDG (1987) Nicotinamide treatment in diabetes. Br J Dermatol 116: 277 Google Scholar
Dulin WE, Wyse DM (1969) Studies on the ability of compounds to block the diabetogenic activity of streptozotocin. Diabetes 18: 458–466 Google Scholar
Pont A, Rubino JM, Bishop D, Peal R (1979) Diabetes mellitus and neuropathy following vacor ingestion in man. Arch Intern Med 139: 185–187 Google Scholar
Okamoto H (1981) Regulation of proinsulin synthesis in pancreatic islets and a new aspect to insulin dependent diabetes. Mol Cell Biochem 37: 43–61 Google Scholar
Uchigata Y, Yamamoto H, Nagai H, Okamoto H (1983) Effect of poly (ADP-ribose) synthetase inhibitor administration to rats before and after injection of alloxan and streptozotocin on islet proinsulin synthesis. Diabetes 32: 316–318 Google Scholar
Sandler S, Andersson A (1986) Long-term effects of exposure of pancreatic islets to nicotinamide in vitro on DNA synthesis, metabolism and B-cell function. Diabetologia 29: 199–202 Google Scholar
Sjöberg S, Gunnarson R, Gjötteberg M, Lefvert AK, Persson A, Östman J (1987) Residual insulin production, glycaemic control and prevalence of microvascular lesions and polyneuropathy in long-term Type 1 (insulin-dependent) diabetes mellitus. Diabetologia 30: 208–213 Google Scholar
Fukuda M, Tanaka A, Tamara Y, Ikegami H, Yamamoto Y, Kumamara Y, Smima K (1988) Correlation between minimal secretory capacity of pancreatic B-cells and stability of diabetic control. Diabetes 37: 81–88 Google Scholar
Winter SL, Boyer JL (1979) Hepatic toxicity from large doses of vitamin B 3 (Nicotinamide). N Engl J Med 283: 1180–1182 Google Scholar
Yamagami T, Miwa A, Takasawa S, Yamamoto H, Okamoto H (1985) Induction of rat pancreatic B-cell tumors by the combined administration of streptozotocin or alloxan and poly (ADP-ribose) synthetase inhibitors. Cancer Res 45: 1845–1849 Google Scholar